|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
137 |
1.000
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
203 |
1.000
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
181 |
1.000
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
198 |
1.000
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
46 |
1.000
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
141 |
1.000
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
181 |
1.000
|
|
|
cellular protein catabolic process
|
GO:0044257 |
213 |
1.000
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.999
|
|
|
proteolysis
|
GO:0006508 |
268 |
0.999
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
363 |
0.998
|
|
|
macromolecule catabolic process
|
GO:0009057 |
383 |
0.964
|
|
|
rrna catabolic process
|
GO:0016075 |
31 |
0.941
|
|
|
ncrna catabolic process
|
GO:0034661 |
33 |
0.889
|
|
|
retrograde protein transport er to cytosol
|
GO:0030970 |
8 |
0.888
|
|
|
single organism catabolic process
|
GO:0044712 |
619 |
0.814
|
|
|
ribosome associated ubiquitin dependent protein catabolic process
|
GO:1990116 |
7 |
0.804
|
|
|
response to organic substance
|
GO:0010033 |
182 |
0.784
|
|
|
misfolded or incompletely synthesized protein catabolic process
|
GO:0006515 |
21 |
0.640
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
144 |
0.561
|
|
|
response to misfolded protein
|
GO:0051788 |
11 |
0.554
|
|
|
organelle fission
|
GO:0048285 |
272 |
0.549
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
172 |
0.497
|
|
|
intracellular protein transport
|
GO:0006886 |
319 |
0.493
|
|
|
rna catabolic process
|
GO:0006401 |
118 |
0.488
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
479 |
0.452
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
376 |
0.430
|
|
|
cell cycle phase transition
|
GO:0044770 |
144 |
0.427
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
32 |
0.424
|
|
|
protein ubiquitination
|
GO:0016567 |
118 |
0.418
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
107 |
0.404
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
38 |
0.397
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
315 |
0.349
|
|
|
positive regulation of gene expression
|
GO:0010628 |
321 |
0.344
|
|
|
single organism membrane organization
|
GO:0044802 |
275 |
0.343
|
|
|
heterocycle catabolic process
|
GO:0046700 |
494 |
0.314
|
|
|
regulation of catalytic activity
|
GO:0050790 |
307 |
0.288
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
499 |
0.281
|
|
|
cellular response to organic substance
|
GO:0071310 |
159 |
0.277
|
|
|
cytoplasm associated proteasomal ubiquitin dependent protein catabolic process
|
GO:0071629 |
5 |
0.269
|
|
|
regulation of molecular function
|
GO:0065009 |
320 |
0.239
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
356 |
0.217
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
178 |
0.212
|
Human Mouse |
|
microtubule based process
|
GO:0007017 |
117 |
0.204
|
|
|
regulation of cellular component organization
|
GO:0051128 |
334 |
0.202
|
|
|
meiotic cell cycle
|
GO:0051321 |
272 |
0.198
|
Worm |
|
cell communication
|
GO:0007154 |
345 |
0.197
|
|
|
protein complex biogenesis
|
GO:0070271 |
314 |
0.196
|
Human Rat |
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
364 |
0.190
|
|
|
chromosome segregation
|
GO:0007059 |
159 |
0.181
|
|
|
single organism signaling
|
GO:0044700 |
208 |
0.178
|
Worm |
|
response to chemical
|
GO:0042221 |
390 |
0.176
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
267 |
0.156
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
332 |
0.155
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
336 |
0.154
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
327 |
0.152
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
491 |
0.151
|
|
|
protein transport
|
GO:0015031 |
345 |
0.149
|
|
|
nucleoside catabolic process
|
GO:0009164 |
335 |
0.146
|
|
|
signaling
|
GO:0023052 |
208 |
0.143
|
Worm |
|
nonfunctional rrna decay
|
GO:0070651 |
12 |
0.143
|
|
|
autophagy
|
GO:0006914 |
106 |
0.141
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
7 |
0.137
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
112 |
0.135
|
Human |
|
mitotic cell cycle
|
GO:0000278 |
306 |
0.132
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
372 |
0.130
|
|
|
regulation of cell cycle
|
GO:0051726 |
195 |
0.124
|
|
|
establishment of organelle localization
|
GO:0051656 |
96 |
0.121
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
109 |
0.118
|
|
|
cytoskeleton organization
|
GO:0007010 |
230 |
0.115
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
494 |
0.115
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
325 |
0.109
|
|
|
nucleotide catabolic process
|
GO:0009166 |
330 |
0.109
|
|
|
protein complex assembly
|
GO:0006461 |
302 |
0.108
|
Human Rat |
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
286 |
0.107
|
|
|
organelle assembly
|
GO:0070925 |
118 |
0.107
|
|
|
nuclear division
|
GO:0000280 |
263 |
0.106
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
45 |
0.104
|
Human |
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
265 |
0.103
|
|
|
establishment of protein localization
|
GO:0045184 |
367 |
0.100
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
50 |
0.098
|
|
|
nucleoside metabolic process
|
GO:0009116 |
394 |
0.095
|
|
|
regulation of protein localization
|
GO:0032880 |
62 |
0.091
|
|
|
membrane organization
|
GO:0061024 |
276 |
0.091
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
116 |
0.086
|
|
|
chromosome localization
|
GO:0050000 |
20 |
0.086
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
286 |
0.084
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
314 |
0.081
|
|
|
spindle organization
|
GO:0007051 |
37 |
0.080
|
|
|
mitotic nuclear division
|
GO:0007067 |
131 |
0.079
|
|
|
translation
|
GO:0006412 |
230 |
0.078
|
|
|
signal transduction
|
GO:0007165 |
208 |
0.078
|
Worm |
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
262 |
0.077
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
377 |
0.077
|
|
|
rrna metabolic process
|
GO:0016072 |
244 |
0.075
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
384 |
0.075
|
|
|
organelle disassembly
|
GO:1903008 |
13 |
0.073
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
327 |
0.073
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
356 |
0.070
|
|
|
piecemeal microautophagy of nucleus
|
GO:0034727 |
33 |
0.069
|
|
|
regulation of cell division
|
GO:0051302 |
113 |
0.064
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
336 |
0.064
|
|
|
organophosphate catabolic process
|
GO:0046434 |
338 |
0.063
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
262 |
0.063
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
224 |
0.062
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
331 |
0.062
|
|
|
maintenance of location
|
GO:0051235 |
66 |
0.060
|
|
|
cellular response to starvation
|
GO:0009267 |
90 |
0.060
|
|
|
maintenance of protein location
|
GO:0045185 |
53 |
0.059
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
141 |
0.059
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
224 |
0.059
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
330 |
0.058
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
394 |
0.058
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
412 |
0.056
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
39 |
0.055
|
Human |
|
sister chromatid segregation
|
GO:0000819 |
93 |
0.055
|
|
|
macroautophagy
|
GO:0016236 |
55 |
0.055
|
|
|
nucleophagy
|
GO:0044804 |
34 |
0.054
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
68 |
0.052
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
332 |
0.051
|
|
|
atp catabolic process
|
GO:0006200 |
224 |
0.050
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
195 |
0.049
|
Human Zebrafish Rat |
|
sexual reproduction
|
GO:0019953 |
216 |
0.049
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
404 |
0.049
|
|
|
cellular protein complex assembly
|
GO:0043623 |
209 |
0.049
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
328 |
0.048
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
327 |
0.047
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
380 |
0.047
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
144 |
0.047
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
112 |
0.046
|
Human Mouse |
|
purine ribonucleotide catabolic process
|
GO:0009154 |
327 |
0.045
|
|
|
fungal type cell wall organization or biogenesis
|
GO:0071852 |
169 |
0.044
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
224 |
0.044
|
|
|
glutamine family amino acid metabolic process
|
GO:0009064 |
31 |
0.043
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
335 |
0.043
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
400 |
0.041
|
|
|
protein localization to nucleus
|
GO:0034504 |
74 |
0.040
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
329 |
0.040
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
329 |
0.040
|
|
|
regulation of dna replication
|
GO:0006275 |
51 |
0.038
|
|
|
multi organism reproductive process
|
GO:0044703 |
216 |
0.037
|
|
|
death
|
GO:0016265 |
30 |
0.036
|
Mouse |
|
regulation of protein metabolic process
|
GO:0051246 |
237 |
0.035
|
|
|
protein localization to organelle
|
GO:0033365 |
337 |
0.035
|
|
|
atp metabolic process
|
GO:0046034 |
251 |
0.034
|
|
|
microtubule anchoring
|
GO:0034453 |
25 |
0.033
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
339 |
0.033
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
55 |
0.032
|
|
|
sister chromatid biorientation
|
GO:0031134 |
8 |
0.032
|
|
|
membrane invagination
|
GO:0010324 |
43 |
0.031
|
|
|
regulation of organelle organization
|
GO:0033043 |
243 |
0.031
|
|
|
nucleotide metabolic process
|
GO:0009117 |
453 |
0.031
|
|
|
glutamine family amino acid biosynthetic process
|
GO:0009084 |
18 |
0.030
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
458 |
0.030
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
28 |
0.030
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
30 |
0.029
|
Human Rat |
|
telomere organization
|
GO:0032200 |
75 |
0.029
|
|
|
regulation of cellular localization
|
GO:0060341 |
50 |
0.029
|
|
|
autophagic vacuole assembly
|
GO:0000045 |
16 |
0.029
|
|
|
cell cycle checkpoint
|
GO:0000075 |
82 |
0.027
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.026
|
|
|
peptide metabolic process
|
GO:0006518 |
28 |
0.025
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
25 |
0.025
|
|
|
mrna processing
|
GO:0006397 |
185 |
0.025
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
25 |
0.024
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
27 |
0.024
|
|
|
cellular amino acid catabolic process
|
GO:0009063 |
48 |
0.024
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
43 |
0.024
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
13 |
0.023
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
287 |
0.023
|
Human |
|
oxoacid metabolic process
|
GO:0043436 |
351 |
0.023
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
409 |
0.022
|
|
|
cellular component disassembly
|
GO:0022411 |
86 |
0.021
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
294 |
0.021
|
|
|
response to extracellular stimulus
|
GO:0009991 |
156 |
0.021
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
232 |
0.021
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
147 |
0.021
|
|
|
protein complex disassembly
|
GO:0043241 |
70 |
0.020
|
|
|
regulation of protein processing
|
GO:0070613 |
34 |
0.020
|
|
|
response to organic cyclic compound
|
GO:0014070 |
1 |
0.020
|
|
|
regulation of catabolic process
|
GO:0009894 |
199 |
0.019
|
Human Zebrafish Rat |
|
single organism developmental process
|
GO:0044767 |
258 |
0.019
|
Zebrafish Worm |
|
mitochondrion organization
|
GO:0007005 |
261 |
0.019
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
39 |
0.019
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
135 |
0.019
|
Human Rat |
|
gene silencing by rna
|
GO:0031047 |
3 |
0.019
|
|
|
inclusion body assembly
|
GO:0070841 |
1 |
0.018
|
Mouse |
|
ergosterol metabolic process
|
GO:0008204 |
31 |
0.018
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
147 |
0.018
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
375 |
0.018
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
86 |
0.018
|
|
|
regulation of cell cycle process
|
GO:0010564 |
150 |
0.017
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
354 |
0.017
|
|
|
multi organism process
|
GO:0051704 |
233 |
0.017
|
|
|
developmental process
|
GO:0032502 |
261 |
0.016
|
Zebrafish Worm |
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.016
|
Worm |
|
reproductive process
|
GO:0022414 |
248 |
0.016
|
Worm |
|
mitotic metaphase plate congression
|
GO:0007080 |
8 |
0.016
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
133 |
0.016
|
Human Mouse |
|
purine nucleoside catabolic process
|
GO:0006152 |
330 |
0.016
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
80 |
0.016
|
|
|
cell development
|
GO:0048468 |
107 |
0.015
|
|
|
cell wall organization
|
GO:0071555 |
146 |
0.015
|
|
|
regulation of phosphorylation
|
GO:0042325 |
86 |
0.015
|
|
|
regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060260 |
19 |
0.015
|
|
|
regulation of biological quality
|
GO:0065008 |
391 |
0.015
|
|
|
response to unfolded protein
|
GO:0006986 |
29 |
0.015
|
Worm |
|
glycogen metabolic process
|
GO:0005977 |
30 |
0.015
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
20 |
0.015
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
389 |
0.014
|
|
|
cellular amide metabolic process
|
GO:0043603 |
59 |
0.014
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
97 |
0.014
|
|
|
programmed cell death
|
GO:0012501 |
30 |
0.014
|
Mouse |
|
maintenance of location in cell
|
GO:0051651 |
58 |
0.014
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
380 |
0.014
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
47 |
0.014
|
|
|
positive regulation of molecular function
|
GO:0044093 |
185 |
0.014
|
Human Mouse |
|
cellular modified amino acid metabolic process
|
GO:0006575 |
51 |
0.014
|
|
|
spindle pole body organization
|
GO:0051300 |
33 |
0.014
|
|
|
aging
|
GO:0007568 |
71 |
0.014
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
224 |
0.013
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
16 |
0.013
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
70 |
0.013
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
150 |
0.013
|
|
|
vacuole organization
|
GO:0007033 |
75 |
0.013
|
|
|
protein deubiquitination
|
GO:0016579 |
17 |
0.012
|
Human |
|
regulation of nuclear division
|
GO:0051783 |
103 |
0.012
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
398 |
0.012
|
|
|
chromatin organization
|
GO:0006325 |
242 |
0.012
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.012
|
|
|
protein folding
|
GO:0006457 |
94 |
0.011
|
|
|
external encapsulating structure organization
|
GO:0045229 |
146 |
0.011
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
160 |
0.011
|
|
|
sporulation resulting in formation of a cellular spore
|
GO:0030435 |
129 |
0.011
|
|
|
glutathione metabolic process
|
GO:0006749 |
16 |
0.011
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
97 |
0.011
|
|
|
cell death
|
GO:0008219 |
30 |
0.010
|
Mouse |
|
chromatin modification
|
GO:0016568 |
200 |
0.010
|
|
|
metaphase plate congression
|
GO:0051310 |
8 |
0.010
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
60 |
0.010
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
54 |
0.010
|
|
|
negative regulation of gene expression
|
GO:0010629 |
312 |
0.010
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
74 |
0.010
|
|
|
negative regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032435 |
24 |
0.010
|
|
|
regulation of chromosome organization
|
GO:0033044 |
66 |
0.010
|
|