Saccharomyces cerevisiae

135 known processes

HDA1 (YNL021W)

Hda1p

HDA1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription dna templated GO:0045892 258 0.994
negative regulation of rna metabolic process GO:0051253 262 0.988
negative regulation of rna biosynthetic process GO:1902679 260 0.982
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.976
negative regulation of cellular biosynthetic process GO:0031327 312 0.973
negative regulation of gene expression GO:0010629 312 0.967
chromatin organization GO:0006325 242 0.966
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.959
negative regulation of nucleic acid templated transcription GO:1903507 260 0.959
negative regulation of biosynthetic process GO:0009890 312 0.957
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.953
histone modification GO:0016570 119 0.952
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.952
gene silencing GO:0016458 151 0.951
chromatin silencing GO:0006342 147 0.926
chromatin modification GO:0016568 200 0.924
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.917
negative regulation of macromolecule metabolic process GO:0010605 375 0.902
negative regulation of cellular metabolic process GO:0031324 407 0.881
covalent chromatin modification GO:0016569 119 0.860
protein deacetylation GO:0006476 26 0.845
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.748
negative regulation of gene expression epigenetic GO:0045814 147 0.707
regulation of gene expression epigenetic GO:0040029 147 0.677
macromolecule deacylation GO:0098732 27 0.636
positive regulation of cellular biosynthetic process GO:0031328 336 0.502
chromatin silencing at silent mating type cassette GO:0030466 53 0.496
dna repair GO:0006281 236 0.492
positive regulation of rna biosynthetic process GO:1902680 286 0.487
cell communication GO:0007154 345 0.442
macromolecule methylation GO:0043414 85 0.432
histone deacetylation GO:0016575 26 0.395
protein deacylation GO:0035601 27 0.322
chromatin silencing at telomere GO:0006348 84 0.319
cellular response to dna damage stimulus GO:0006974 287 0.297
positive regulation of transcription dna templated GO:0045893 286 0.273
positive regulation of gene expression GO:0010628 321 0.260
mitotic cell cycle process GO:1903047 294 0.238
positive regulation of macromolecule metabolic process GO:0010604 394 0.228
chromosome segregation GO:0007059 159 0.226
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.214
carboxylic acid metabolic process GO:0019752 338 0.209
double strand break repair GO:0006302 105 0.196
cell cycle phase transition GO:0044770 144 0.182
oxoacid metabolic process GO:0043436 351 0.171
positive regulation of nucleic acid templated transcription GO:1903508 286 0.160
peptidyl lysine modification GO:0018205 77 0.160
regulation of response to stimulus GO:0048583 157 0.157
mitotic cell cycle GO:0000278 306 0.144
dna replication GO:0006260 147 0.134
methylation GO:0032259 101 0.130
carboxylic acid biosynthetic process GO:0046394 152 0.129
positive regulation of rna metabolic process GO:0051254 294 0.127
mitotic cell cycle phase transition GO:0044772 141 0.122
single organism developmental process GO:0044767 258 0.113
response to abiotic stimulus GO:0009628 159 0.113
developmental process GO:0032502 261 0.112
regulation of biological quality GO:0065008 391 0.112
homeostatic process GO:0042592 227 0.108
nucleosome organization GO:0034728 63 0.108
response to external stimulus GO:0009605 158 0.108
cellular response to nutrient GO:0031670 50 0.107
single organism membrane organization GO:0044802 275 0.107
cellular chemical homeostasis GO:0055082 123 0.105
peptidyl amino acid modification GO:0018193 116 0.101
organelle fission GO:0048285 272 0.095
regulation of cellular ketone metabolic process GO:0010565 42 0.087
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.086
response to chemical GO:0042221 390 0.082
mating type determination GO:0007531 32 0.081
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.081
chromatin remodeling GO:0006338 80 0.079
developmental process involved in reproduction GO:0003006 159 0.079
cell cycle g1 s phase transition GO:0044843 64 0.078
response to nutrient levels GO:0031667 150 0.077
aromatic compound catabolic process GO:0019439 491 0.076
cellular response to extracellular stimulus GO:0031668 150 0.075
cell aging GO:0007569 70 0.074
regulation of chromosome organization GO:0033044 66 0.073
regulation of lipid metabolic process GO:0019216 45 0.073
carbohydrate metabolic process GO:0005975 252 0.071
regulation of catabolic process GO:0009894 199 0.070
signal transduction GO:0007165 208 0.069
organic anion transport GO:0015711 114 0.067
filamentous growth GO:0030447 124 0.065
carbohydrate derivative metabolic process GO:1901135 549 0.064
organic acid metabolic process GO:0006082 352 0.064
ion transport GO:0006811 274 0.063
sex determination GO:0007530 32 0.062
aging GO:0007568 71 0.061
intracellular signal transduction GO:0035556 112 0.060
mrna processing GO:0006397 185 0.059
small molecule biosynthetic process GO:0044283 258 0.057
ribose phosphate metabolic process GO:0019693 384 0.057
growth GO:0040007 157 0.056
negative regulation of cell cycle GO:0045786 91 0.056
invasive filamentous growth GO:0036267 65 0.056
chromatin assembly or disassembly GO:0006333 60 0.056
nucleobase containing compound catabolic process GO:0034655 479 0.056
single organism reproductive process GO:0044702 159 0.055
regulation of cell communication GO:0010646 124 0.055
negative regulation of mitotic cell cycle GO:0045930 63 0.055
regulation of molecular function GO:0065009 320 0.055
g1 s transition of mitotic cell cycle GO:0000082 64 0.054
filamentous growth of a population of unicellular organisms GO:0044182 109 0.054
protein methylation GO:0006479 48 0.054
reproduction of a single celled organism GO:0032505 191 0.054
positive regulation of biosynthetic process GO:0009891 336 0.053
regulation of protein metabolic process GO:0051246 237 0.052
regulation of signal transduction GO:0009966 114 0.051
regulation of cell cycle phase transition GO:1901987 70 0.051
organic acid biosynthetic process GO:0016053 152 0.051
lipid metabolic process GO:0006629 269 0.050
response to heat GO:0009408 69 0.050
organic cyclic compound catabolic process GO:1901361 499 0.049
cellular lipid metabolic process GO:0044255 229 0.048
organophosphate metabolic process GO:0019637 597 0.048
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.047
gene silencing by rna GO:0031047 3 0.046
cellular metal ion homeostasis GO:0006875 78 0.045
carbohydrate biosynthetic process GO:0016051 82 0.045
regulation of growth GO:0040008 50 0.045
mitotic nuclear division GO:0007067 131 0.044
cellular response to organic substance GO:0071310 159 0.043
cellular response to chemical stimulus GO:0070887 315 0.043
cellular ketone metabolic process GO:0042180 63 0.042
ribonucleoprotein complex assembly GO:0022618 143 0.042
lipid biosynthetic process GO:0008610 170 0.042
regulation of dna metabolic process GO:0051052 100 0.042
cellular nitrogen compound catabolic process GO:0044270 494 0.042
membrane organization GO:0061024 276 0.042
positive regulation of catalytic activity GO:0043085 178 0.039
regulation of chromatin silencing GO:0031935 39 0.038
mrna metabolic process GO:0016071 269 0.038
metal ion homeostasis GO:0055065 79 0.038
nuclear division GO:0000280 263 0.038
dna templated transcription termination GO:0006353 42 0.037
anion transport GO:0006820 145 0.037
protein maturation GO:0051604 76 0.037
regulation of dna dependent dna replication initiation GO:0030174 21 0.037
cellular amine metabolic process GO:0044106 51 0.037
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.037
cellular response to nutrient levels GO:0031669 144 0.037
purine ribonucleoside catabolic process GO:0046130 330 0.036
regulation of cellular response to stress GO:0080135 50 0.036
purine nucleoside catabolic process GO:0006152 330 0.036
single organism cellular localization GO:1902580 375 0.036
dna replication initiation GO:0006270 48 0.036
regulation of cellular catabolic process GO:0031329 195 0.035
regulation of response to dna damage stimulus GO:2001020 17 0.035
cell wall biogenesis GO:0042546 93 0.035
histone methylation GO:0016571 28 0.035
regulation of carbohydrate biosynthetic process GO:0043255 31 0.034
response to extracellular stimulus GO:0009991 156 0.033
purine ribonucleotide catabolic process GO:0009154 327 0.033
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.032
protein alkylation GO:0008213 48 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.032
protein targeting GO:0006605 272 0.032
dna dependent dna replication GO:0006261 115 0.032
regulation of mitotic cell cycle GO:0007346 107 0.032
cellular macromolecule catabolic process GO:0044265 363 0.032
regulation of lipid biosynthetic process GO:0046890 32 0.032
ncrna processing GO:0034470 330 0.031
protein modification by small protein conjugation GO:0032446 144 0.031
nucleoside triphosphate catabolic process GO:0009143 329 0.031
protein processing GO:0016485 64 0.030
single organism carbohydrate metabolic process GO:0044723 237 0.030
purine nucleotide catabolic process GO:0006195 328 0.030
purine containing compound catabolic process GO:0072523 332 0.030
response to organic substance GO:0010033 182 0.029
regulation of carbohydrate metabolic process GO:0006109 43 0.029
single organism catabolic process GO:0044712 619 0.028
mitotic sister chromatid segregation GO:0000070 85 0.027
regulation of hydrolase activity GO:0051336 133 0.027
invasive growth in response to glucose limitation GO:0001403 61 0.027
purine nucleoside triphosphate catabolic process GO:0009146 329 0.027
regulation of chromatin organization GO:1902275 23 0.027
inorganic ion transmembrane transport GO:0098660 109 0.027
regulation of phosphate metabolic process GO:0019220 230 0.027
regulation of cell cycle GO:0051726 195 0.027
cellular developmental process GO:0048869 191 0.027
posttranscriptional regulation of gene expression GO:0010608 115 0.026
mrna splicing via spliceosome GO:0000398 108 0.026
ribonucleoside catabolic process GO:0042454 332 0.026
negative regulation of organelle organization GO:0010639 103 0.026
regulation of dna dependent dna replication GO:0090329 37 0.026
ribonucleotide catabolic process GO:0009261 327 0.026
amide transport GO:0042886 22 0.025
cellular response to oxygen containing compound GO:1901701 43 0.025
regulation of filamentous growth of a population of unicellular organisms GO:1900428 36 0.025
protein acylation GO:0043543 66 0.025
reproductive process GO:0022414 248 0.025
glycosyl compound catabolic process GO:1901658 335 0.025
autophagy GO:0006914 106 0.025
internal protein amino acid acetylation GO:0006475 52 0.024
positive regulation of molecular function GO:0044093 185 0.024
regulation of transport GO:0051049 85 0.024
cellular carbohydrate metabolic process GO:0044262 135 0.024
chromatin silencing at rdna GO:0000183 32 0.024
multi organism process GO:0051704 233 0.024
protein localization to organelle GO:0033365 337 0.024
nucleoside catabolic process GO:0009164 335 0.024
regulation of cell cycle process GO:0010564 150 0.024
dna packaging GO:0006323 55 0.024
cellular amino acid biosynthetic process GO:0008652 118 0.023
nucleotide catabolic process GO:0009166 330 0.023
heterocycle catabolic process GO:0046700 494 0.023
regulation of filamentous growth GO:0010570 38 0.023
dna conformation change GO:0071103 98 0.022
cellular amino acid metabolic process GO:0006520 225 0.022
dna integrity checkpoint GO:0031570 41 0.022
cellular homeostasis GO:0019725 138 0.022
carbohydrate derivative biosynthetic process GO:1901137 181 0.022
response to temperature stimulus GO:0009266 74 0.022
regulation of catalytic activity GO:0050790 307 0.022
cell fate commitment GO:0045165 32 0.021
regulation of localization GO:0032879 127 0.021
fungal type cell wall biogenesis GO:0009272 80 0.021
carbohydrate derivative catabolic process GO:1901136 339 0.021
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.021
amine metabolic process GO:0009308 51 0.021
cellular polysaccharide metabolic process GO:0044264 55 0.021
cellular response to oxidative stress GO:0034599 94 0.021
multi organism reproductive process GO:0044703 216 0.021
maintenance of location in cell GO:0051651 58 0.021
regulation of response to stress GO:0080134 57 0.021
nucleobase containing small molecule metabolic process GO:0055086 491 0.021
histone lysine methylation GO:0034968 26 0.020
nitrogen compound transport GO:0071705 212 0.020
cellular response to external stimulus GO:0071496 150 0.020
regulation of cellular component organization GO:0051128 334 0.020
ribonucleoside monophosphate catabolic process GO:0009158 224 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.020
organophosphate catabolic process GO:0046434 338 0.020
ribonucleoprotein complex subunit organization GO:0071826 152 0.020
negative regulation of cell cycle process GO:0010948 86 0.020
mrna 3 end processing GO:0031124 54 0.020
purine ribonucleotide metabolic process GO:0009150 372 0.019
protein acetylation GO:0006473 59 0.019
ascospore formation GO:0030437 107 0.019
regulation of dna replication GO:0006275 51 0.019
regulation of phosphorus metabolic process GO:0051174 230 0.019
atp metabolic process GO:0046034 251 0.019
glycosyl compound metabolic process GO:1901657 398 0.019
glycoprotein biosynthetic process GO:0009101 61 0.019
sexual sporulation GO:0034293 113 0.018
negative regulation of dna metabolic process GO:0051053 36 0.018
meiotic cell cycle GO:0051321 272 0.018
maintenance of protein location in cell GO:0032507 50 0.018
single organism signaling GO:0044700 208 0.018
dna damage checkpoint GO:0000077 29 0.018
negative regulation of cell cycle phase transition GO:1901988 59 0.017
multi organism cellular process GO:0044764 120 0.017
atp catabolic process GO:0006200 224 0.017
regulation of signaling GO:0023051 119 0.017
maintenance of location GO:0051235 66 0.017
ribonucleoside triphosphate catabolic process GO:0009203 327 0.017
organonitrogen compound biosynthetic process GO:1901566 314 0.017
regulation of nuclear division GO:0051783 103 0.017
double strand break repair via nonhomologous end joining GO:0006303 27 0.017
vesicle mediated transport GO:0016192 335 0.017
cell differentiation GO:0030154 161 0.017
negative regulation of cell division GO:0051782 66 0.016
cellular ion homeostasis GO:0006873 112 0.016
death GO:0016265 30 0.016
protein ubiquitination GO:0016567 118 0.016
ribonucleoside triphosphate metabolic process GO:0009199 356 0.016
protein localization to nucleus GO:0034504 74 0.016
organonitrogen compound catabolic process GO:1901565 404 0.016
alcohol biosynthetic process GO:0046165 75 0.015
response to inorganic substance GO:0010035 47 0.015
negative regulation of nuclear division GO:0051784 62 0.015
organic acid transport GO:0015849 77 0.015
telomere organization GO:0032200 75 0.015
transfer rna gene mediated silencing GO:0061587 14 0.014
rna splicing GO:0008380 131 0.014
regulation of dna recombination GO:0000018 24 0.014
regulation of cellular amine metabolic process GO:0033238 21 0.014
nucleoside phosphate catabolic process GO:1901292 331 0.014
reproductive process in single celled organism GO:0022413 145 0.014
regulation of mitotic cell cycle phase transition GO:1901990 68 0.014
regulation of cellular amino acid metabolic process GO:0006521 16 0.014
proteolysis GO:0006508 268 0.014
transmembrane transport GO:0055085 349 0.014
establishment of protein localization to membrane GO:0090150 99 0.014
regulation of organelle organization GO:0033043 243 0.014
generation of precursor metabolites and energy GO:0006091 147 0.014
positive regulation of secretion GO:0051047 2 0.013
response to starvation GO:0042594 96 0.013
oxidation reduction process GO:0055114 353 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.013
regulation of histone modification GO:0031056 18 0.013
protein dna complex subunit organization GO:0071824 153 0.013
response to oxygen containing compound GO:1901700 61 0.013
response to organic cyclic compound GO:0014070 1 0.013
establishment of protein localization to organelle GO:0072594 278 0.013
positive regulation of catabolic process GO:0009896 135 0.012
cellular response to reactive oxygen species GO:0034614 16 0.012
monocarboxylic acid biosynthetic process GO:0072330 35 0.012
negative regulation of cellular component organization GO:0051129 109 0.012
nucleoside triphosphate metabolic process GO:0009141 364 0.012
nucleobase containing compound transport GO:0015931 124 0.012
ribosome biogenesis GO:0042254 335 0.012
ribonucleoside metabolic process GO:0009119 389 0.012
atp dependent chromatin remodeling GO:0043044 36 0.012
trna processing GO:0008033 101 0.012
positive regulation of cellular catabolic process GO:0031331 128 0.012
cellular transition metal ion homeostasis GO:0046916 59 0.012
sulfur compound metabolic process GO:0006790 95 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.012
ribosomal small subunit biogenesis GO:0042274 124 0.012
peptide transport GO:0015833 14 0.012
snorna processing GO:0043144 34 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
cell growth GO:0016049 89 0.011
peptidyl lysine acetylation GO:0018394 52 0.011
organophosphate ester transport GO:0015748 45 0.011
carbohydrate catabolic process GO:0016052 77 0.011
positive regulation of cellular amine metabolic process GO:0033240 10 0.011
purine nucleoside triphosphate metabolic process GO:0009144 356 0.011
internal peptidyl lysine acetylation GO:0018393 52 0.011
trna modification GO:0006400 75 0.011
positive regulation of hydrolase activity GO:0051345 112 0.011
monocarboxylic acid metabolic process GO:0032787 122 0.011
positive regulation of secretion by cell GO:1903532 2 0.011
meiotic nuclear division GO:0007126 163 0.011
regulation of rna splicing GO:0043484 3 0.011
signaling GO:0023052 208 0.011
response to oxidative stress GO:0006979 99 0.011
cellular component disassembly GO:0022411 86 0.011
fatty acid biosynthetic process GO:0006633 22 0.011
negative regulation of cellular catabolic process GO:0031330 43 0.011
regulation of cellular localization GO:0060341 50 0.011
nuclear export GO:0051168 124 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.010
ribonucleotide metabolic process GO:0009259 377 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.010
cellular modified amino acid metabolic process GO:0006575 51 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.010
purine nucleoside monophosphate catabolic process GO:0009128 224 0.010
regulation of translation GO:0006417 89 0.010
exit from mitosis GO:0010458 37 0.010
response to endogenous stimulus GO:0009719 26 0.010
regulation of cell growth GO:0001558 29 0.010

HDA1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017