Saccharomyces cerevisiae

79 known processes

IRE1 (YHR079C)

Ire1p

(Aliases: ERN1)

IRE1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of macromolecule metabolic process GO:0010605 375 0.774
Human
signal transduction GO:0007165 208 0.687
single organism signaling GO:0044700 208 0.537
nuclear division GO:0000280 263 0.521
cell communication GO:0007154 345 0.484
negative regulation of cellular metabolic process GO:0031324 407 0.478
Human
organelle fission GO:0048285 272 0.430
mitotic cell cycle process GO:1903047 294 0.422
lipid metabolic process GO:0006629 269 0.419
negative regulation of biosynthetic process GO:0009890 312 0.373
Human
cellular response to chemical stimulus GO:0070887 315 0.357
regulation of cell cycle process GO:0010564 150 0.349
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.346
Human
response to chemical GO:0042221 390 0.343
fungal type cell wall organization or biogenesis GO:0071852 169 0.341
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.331
Human
regulation of cell cycle GO:0051726 195 0.258
Mouse
meiotic cell cycle GO:0051321 272 0.254
mitotic cell cycle phase transition GO:0044772 141 0.240
negative regulation of cellular biosynthetic process GO:0031327 312 0.216
Human
cell division GO:0051301 205 0.212
single organism carbohydrate metabolic process GO:0044723 237 0.211
lipid biosynthetic process GO:0008610 170 0.210
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.203
Human
chromatin modification GO:0016568 200 0.192
protein complex assembly GO:0006461 302 0.191
regulation of cell division GO:0051302 113 0.187
cellular response to organic substance GO:0071310 159 0.165
cellular macromolecule catabolic process GO:0044265 363 0.157
Human
negative regulation of transcription dna templated GO:0045892 258 0.154
Human
negative regulation of cell division GO:0051782 66 0.145
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.141
Human
regulation of cellular component organization GO:0051128 334 0.132
regulation of organelle organization GO:0033043 243 0.129
positive regulation of gene expression GO:0010628 321 0.123
Human
negative regulation of gene expression GO:0010629 312 0.122
Human
reproductive process GO:0022414 248 0.119
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.119
regulation of mitotic cell cycle phase transition GO:1901990 68 0.106
meiotic nuclear division GO:0007126 163 0.105
chromatin organization GO:0006325 242 0.104
signaling GO:0023052 208 0.103
mitotic cell cycle GO:0000278 306 0.101
sexual reproduction GO:0019953 216 0.100
cell wall organization GO:0071555 146 0.099
regulation of cellular protein metabolic process GO:0032268 232 0.095
Human
negative regulation of cell cycle process GO:0010948 86 0.091
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.088
Human
regulation of nuclear division GO:0051783 103 0.088
cellular lipid metabolic process GO:0044255 229 0.086
regulation of mitotic cell cycle GO:0007346 107 0.086
cell wall organization or biogenesis GO:0071554 190 0.085
negative regulation of nucleic acid templated transcription GO:1903507 260 0.084
Human
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.081
Human
organophosphate metabolic process GO:0019637 597 0.079
positive regulation of nucleic acid templated transcription GO:1903508 286 0.072
carbohydrate derivative metabolic process GO:1901135 549 0.071
regulation of catalytic activity GO:0050790 307 0.067
Human
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.067
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.065
positive regulation of catalytic activity GO:0043085 178 0.065
Human
carbohydrate metabolic process GO:0005975 252 0.065
positive regulation of transcription dna templated GO:0045893 286 0.063
cell cycle phase transition GO:0044770 144 0.062
regulation of molecular function GO:0065009 320 0.060
Human
cellular nitrogen compound catabolic process GO:0044270 494 0.059
Human
negative regulation of rna biosynthetic process GO:1902679 260 0.059
Human
organophosphate biosynthetic process GO:0090407 182 0.058
regulation of phosphorus metabolic process GO:0051174 230 0.056
Human
regulation of cellular catabolic process GO:0031329 195 0.056
positive regulation of rna biosynthetic process GO:1902680 286 0.055
positive regulation of macromolecule metabolic process GO:0010604 394 0.055
Human
organic cyclic compound catabolic process GO:1901361 499 0.054
Human
covalent chromatin modification GO:0016569 119 0.053
macromolecule catabolic process GO:0009057 383 0.053
Human
negative regulation of organelle organization GO:0010639 103 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.050
glycerolipid biosynthetic process GO:0045017 71 0.050
positive regulation of phosphate metabolic process GO:0045937 147 0.049
Human
response to organic substance GO:0010033 182 0.048
heterocycle catabolic process GO:0046700 494 0.046
Human
regulation of cell cycle phase transition GO:1901987 70 0.046
cellular component disassembly GO:0022411 86 0.046
Human
regulation of protein modification process GO:0031399 110 0.044
Human
glycerophospholipid metabolic process GO:0006650 98 0.044
phospholipid metabolic process GO:0006644 125 0.043
multi organism process GO:0051704 233 0.043
regulation of catabolic process GO:0009894 199 0.042
negative regulation of cellular protein metabolic process GO:0032269 85 0.041
cellular response to topologically incorrect protein GO:0035967 32 0.040
phosphorylation GO:0016310 291 0.040
protein complex biogenesis GO:0070271 314 0.040
negative regulation of protein metabolic process GO:0051248 85 0.040
glycerolipid metabolic process GO:0046486 108 0.039
regulation of chromosome organization GO:0033044 66 0.039
response to abiotic stimulus GO:0009628 159 0.037
regulation of protein metabolic process GO:0051246 237 0.037
Human
response to temperature stimulus GO:0009266 74 0.033
mitotic nuclear division GO:0007067 131 0.033
modification dependent protein catabolic process GO:0019941 181 0.032
protein phosphorylation GO:0006468 197 0.031
fungal type cell wall organization GO:0031505 145 0.031
gene silencing GO:0016458 151 0.031
multi organism cellular process GO:0044764 120 0.030
response to nutrient levels GO:0031667 150 0.030
regulation of phosphate metabolic process GO:0019220 230 0.030
Human
rna catabolic process GO:0006401 118 0.029
Human
multi organism reproductive process GO:0044703 216 0.029
cell surface receptor signaling pathway GO:0007166 38 0.029
sporulation GO:0043934 132 0.029
sporulation resulting in formation of a cellular spore GO:0030435 129 0.029
single organism catabolic process GO:0044712 619 0.029
regulation of gene expression epigenetic GO:0040029 147 0.028
organic hydroxy compound metabolic process GO:1901615 125 0.028
nucleobase containing compound catabolic process GO:0034655 479 0.027
Human
nucleobase containing small molecule metabolic process GO:0055086 491 0.027
response to osmotic stress GO:0006970 83 0.027
ncrna processing GO:0034470 330 0.027
g1 s transition of mitotic cell cycle GO:0000082 64 0.027
conjugation with cellular fusion GO:0000747 106 0.027
carboxylic acid metabolic process GO:0019752 338 0.027
anatomical structure formation involved in morphogenesis GO:0048646 136 0.026
protein catabolic process GO:0030163 221 0.026
response to external stimulus GO:0009605 158 0.026
positive regulation of cellular biosynthetic process GO:0031328 336 0.026
positive regulation of rna metabolic process GO:0051254 294 0.026
Human
cell cycle g1 s phase transition GO:0044843 64 0.026
histone modification GO:0016570 119 0.026
positive regulation of molecular function GO:0044093 185 0.026
Human
alcohol metabolic process GO:0006066 112 0.025
negative regulation of rna metabolic process GO:0051253 262 0.025
Human
external encapsulating structure organization GO:0045229 146 0.025
cellular protein catabolic process GO:0044257 213 0.025
carbohydrate derivative biosynthetic process GO:1901137 181 0.025
single organism membrane organization GO:0044802 275 0.025
phosphatidylinositol metabolic process GO:0046488 62 0.025
single organism developmental process GO:0044767 258 0.022
macromolecular complex disassembly GO:0032984 80 0.022
cellular protein complex assembly GO:0043623 209 0.022
regulation of signal transduction GO:0009966 114 0.022
Human
peptidyl amino acid modification GO:0018193 116 0.021
regulation of biological quality GO:0065008 391 0.020
cellular ketone metabolic process GO:0042180 63 0.020
regulation of meiosis GO:0040020 42 0.020
response to endoplasmic reticulum stress GO:0034976 23 0.020
response to topologically incorrect protein GO:0035966 38 0.020
phospholipid biosynthetic process GO:0008654 89 0.019
chromatin silencing GO:0006342 147 0.019
protein localization to organelle GO:0033365 337 0.019
nitrogen compound transport GO:0071705 212 0.019
cellular response to external stimulus GO:0071496 150 0.019
aromatic compound catabolic process GO:0019439 491 0.019
Human
response to heat GO:0009408 69 0.019
developmental process involved in reproduction GO:0003006 159 0.019
cellular response to dna damage stimulus GO:0006974 287 0.019
membrane organization GO:0061024 276 0.018
proteasomal protein catabolic process GO:0010498 141 0.018
negative regulation of cellular component organization GO:0051129 109 0.018
negative regulation of cell cycle GO:0045786 91 0.018
Mouse
cellular developmental process GO:0048869 191 0.017
cell development GO:0048468 107 0.017
cellular response to nutrient levels GO:0031669 144 0.017
polysaccharide biosynthetic process GO:0000271 39 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.017
negative regulation of chromosome organization GO:2001251 39 0.017
glycoprotein metabolic process GO:0009100 62 0.017
positive regulation of phosphorus metabolic process GO:0010562 147 0.016
Human
fatty acid metabolic process GO:0006631 51 0.016
mrna metabolic process GO:0016071 269 0.016
Human
protein maturation GO:0051604 76 0.016
membrane lipid metabolic process GO:0006643 67 0.016
cellular response to unfolded protein GO:0034620 23 0.016
polysaccharide metabolic process GO:0005976 60 0.016
regulation of cellular protein catabolic process GO:1903362 36 0.015
developmental process GO:0032502 261 0.015
regulation of protein complex assembly GO:0043254 77 0.015
nucleoside phosphate catabolic process GO:1901292 331 0.015
regulation of dna replication GO:0006275 51 0.015
negative regulation of dna metabolic process GO:0051053 36 0.015
posttranscriptional regulation of gene expression GO:0010608 115 0.015
nucleotide metabolic process GO:0009117 453 0.015
cellular response to extracellular stimulus GO:0031668 150 0.015
organic acid biosynthetic process GO:0016053 152 0.015
chromosome segregation GO:0007059 159 0.015
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.015
protein targeting to membrane GO:0006612 52 0.015
ubiquitin dependent protein catabolic process GO:0006511 181 0.014
small molecule biosynthetic process GO:0044283 258 0.014
establishment of protein localization to membrane GO:0090150 99 0.014
growth GO:0040007 157 0.014
regulation of response to stimulus GO:0048583 157 0.014
Human
regulation of dna templated transcription in response to stress GO:0043620 51 0.014
protein glycosylation GO:0006486 57 0.013
cytoskeleton organization GO:0007010 230 0.013
purine ribonucleoside catabolic process GO:0046130 330 0.013
conjugation GO:0000746 107 0.013
endoplasmic reticulum unfolded protein response GO:0030968 23 0.013
ribonucleotide metabolic process GO:0009259 377 0.013
regulation of meiotic cell cycle GO:0051445 43 0.013
cellular response to osmotic stress GO:0071470 50 0.013
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.013
dna templated transcription termination GO:0006353 42 0.013
purine nucleoside catabolic process GO:0006152 330 0.013
vesicle mediated transport GO:0016192 335 0.013
organophosphate catabolic process GO:0046434 338 0.013
membrane lipid biosynthetic process GO:0046467 54 0.012
negative regulation of nuclear division GO:0051784 62 0.012
dephosphorylation GO:0016311 127 0.012
regulation of mitosis GO:0007088 65 0.012
positive regulation of biosynthetic process GO:0009891 336 0.012
nucleotide catabolic process GO:0009166 330 0.012
positive regulation of mitotic cell cycle GO:0045931 16 0.012
positive regulation of protein metabolic process GO:0051247 93 0.012
Human
protein modification by small protein conjugation or removal GO:0070647 172 0.012
reproduction of a single celled organism GO:0032505 191 0.011
g protein coupled receptor signaling pathway GO:0007186 37 0.011
purine containing compound catabolic process GO:0072523 332 0.011
negative regulation of molecular function GO:0044092 68 0.011
protein complex disassembly GO:0043241 70 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.011
amine metabolic process GO:0009308 51 0.011
glycosyl compound catabolic process GO:1901658 335 0.011
glycerophospholipid biosynthetic process GO:0046474 68 0.011
septin ring organization GO:0031106 26 0.011
carbohydrate derivative catabolic process GO:1901136 339 0.011
generation of precursor metabolites and energy GO:0006091 147 0.011
ras protein signal transduction GO:0007265 29 0.011
cell cycle checkpoint GO:0000075 82 0.011
response to unfolded protein GO:0006986 29 0.010
ascospore formation GO:0030437 107 0.010
regulation of hydrolase activity GO:0051336 133 0.010
Human
response to organic cyclic compound GO:0014070 1 0.010
meiotic cell cycle process GO:1903046 229 0.010
protein transport GO:0015031 345 0.010
oxoacid metabolic process GO:0043436 351 0.010
regulation of purine nucleotide metabolic process GO:1900542 109 0.010
cellular carbohydrate metabolic process GO:0044262 135 0.010
positive regulation of cellular catabolic process GO:0031331 128 0.010
negative regulation of phosphate metabolic process GO:0045936 49 0.010

IRE1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org