Saccharomyces cerevisiae

42 known processes

CLN1 (YMR199W)

Cln1p

CLN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein serine threonine kinase activity GO:0071900 41 0.935
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 19 0.923
regulation of protein kinase activity GO:0045859 67 0.921
cell cycle g1 s phase transition GO:0044843 64 0.827
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.624
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 27 0.619
g1 s transition of mitotic cell cycle GO:0000082 64 0.569
cell cycle phase transition GO:0044770 144 0.562
regulation of phosphorylation GO:0042325 86 0.535
spindle pole body organization GO:0051300 33 0.530
regulation of transferase activity GO:0051338 83 0.510
regulation of kinase activity GO:0043549 71 0.505
regulation of protein phosphorylation GO:0001932 75 0.496
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.478
regulation of phosphorus metabolic process GO:0051174 230 0.456
mitotic cell cycle phase transition GO:0044772 141 0.447
negative regulation of gene expression GO:0010629 312 0.443
regulation of cell cycle GO:0051726 195 0.426
protein phosphorylation GO:0006468 197 0.415
regulation of phosphate metabolic process GO:0019220 230 0.406
chromatin organization GO:0006325 242 0.385
regulation of cellular protein metabolic process GO:0032268 232 0.380
regulation of protein modification process GO:0031399 110 0.370
positive regulation of gene expression GO:0010628 321 0.366
phosphorylation GO:0016310 291 0.366
mitotic cell cycle process GO:1903047 294 0.366
chromatin modification GO:0016568 200 0.364
negative regulation of macromolecule metabolic process GO:0010605 375 0.354
positive regulation of cellular biosynthetic process GO:0031328 336 0.311
negative regulation of cellular metabolic process GO:0031324 407 0.285
positive regulation of rna metabolic process GO:0051254 294 0.274
cytoskeleton organization GO:0007010 230 0.268
negative regulation of nucleic acid templated transcription GO:1903507 260 0.243
positive regulation of nucleic acid templated transcription GO:1903508 286 0.241
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.232
negative regulation of rna biosynthetic process GO:1902679 260 0.229
adaptation of signaling pathway GO:0023058 23 0.221
negative regulation of cellular biosynthetic process GO:0031327 312 0.221
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.218
negative regulation of rna metabolic process GO:0051253 262 0.217
cellular response to nutrient levels GO:0031669 144 0.212
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.206
protein complex assembly GO:0006461 302 0.197
positive regulation of transcription dna templated GO:0045893 286 0.195
regulation of response to nutrient levels GO:0032107 20 0.185
autophagy GO:0006914 106 0.181
small molecule biosynthetic process GO:0044283 258 0.175
regulation of cytoskeleton organization GO:0051493 63 0.171
mrna processing GO:0006397 185 0.170
g2 m transition of mitotic cell cycle GO:0000086 38 0.169
protein complex biogenesis GO:0070271 314 0.168
mitotic cell cycle GO:0000278 306 0.165
negative regulation of transcription dna templated GO:0045892 258 0.165
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.163
positive regulation of spindle pole body separation GO:0010696 7 0.158
cell division GO:0051301 205 0.157
regulation of molecular function GO:0065009 320 0.157
single organism carbohydrate metabolic process GO:0044723 237 0.153
regulation of protein metabolic process GO:0051246 237 0.153
regulation of chromatin modification GO:1903308 23 0.152
negative regulation of biosynthetic process GO:0009890 312 0.147
cellular response to extracellular stimulus GO:0031668 150 0.146
macroautophagy GO:0016236 55 0.144
developmental process GO:0032502 261 0.143
regulation of response to external stimulus GO:0032101 20 0.141
regulation of spindle pole body separation GO:0010695 9 0.140
mrna metabolic process GO:0016071 269 0.139
adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion GO:0000754 23 0.136
reproduction of a single celled organism GO:0032505 191 0.136
response to nutrient levels GO:0031667 150 0.135
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.134
cellular amino acid biosynthetic process GO:0008652 118 0.132
microtubule cytoskeleton organization GO:0000226 109 0.129
chromosome condensation GO:0030261 19 0.127
dna replication GO:0006260 147 0.125
growth GO:0040007 157 0.124
cellular response to chemical stimulus GO:0070887 315 0.124
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.123
mrna 3 end processing GO:0031124 54 0.123
regulation of response to stimulus GO:0048583 157 0.117
positive regulation of phosphorus metabolic process GO:0010562 147 0.113
cellular response to external stimulus GO:0071496 150 0.107
regulation of dna metabolic process GO:0051052 100 0.105
response to chemical GO:0042221 390 0.104
cellular amino acid metabolic process GO:0006520 225 0.103
regulation of catalytic activity GO:0050790 307 0.100
cytoskeleton dependent cytokinesis GO:0061640 65 0.100
establishment or maintenance of cell polarity GO:0007163 96 0.100
negative regulation of protein phosphorylation GO:0001933 24 0.099
reproductive process GO:0022414 248 0.099
asexual reproduction GO:0019954 48 0.099
response to starvation GO:0042594 96 0.096
single organism developmental process GO:0044767 258 0.096
positive regulation of macromolecule metabolic process GO:0010604 394 0.094
maintenance of protein location in cell GO:0032507 50 0.092
response to organic substance GO:0010033 182 0.091
nucleoside phosphate biosynthetic process GO:1901293 80 0.090
positive regulation of cytoskeleton organization GO:0051495 39 0.084
cell fate commitment GO:0045165 32 0.084
cell cycle g2 m phase transition GO:0044839 39 0.083
regulation of chromosome condensation GO:0060623 2 0.082
response to abiotic stimulus GO:0009628 159 0.081
response to extracellular stimulus GO:0009991 156 0.081
chromatin remodeling GO:0006338 80 0.080
purine containing compound metabolic process GO:0072521 400 0.078
organic acid biosynthetic process GO:0016053 152 0.078
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 7 0.076
maintenance of location in cell GO:0051651 58 0.073
establishment of organelle localization GO:0051656 96 0.073
regulation of cell cycle process GO:0010564 150 0.072
attachment of spindle microtubules to kinetochore GO:0008608 25 0.071
microtubule polymerization or depolymerization GO:0031109 36 0.070
positive regulation of rna biosynthetic process GO:1902680 286 0.069
regulation of mitotic cell cycle GO:0007346 107 0.069
meiotic g2 mi transition GO:0008315 1 0.068
mitotic cell cycle checkpoint GO:0007093 56 0.068
single organism catabolic process GO:0044712 619 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.067
cytokinesis GO:0000910 92 0.066
microtubule anchoring GO:0034453 25 0.066
oxoacid metabolic process GO:0043436 351 0.066
mitochondrion organization GO:0007005 261 0.066
regulation of organelle organization GO:0033043 243 0.066
cell communication GO:0007154 345 0.065
cellular response to organic substance GO:0071310 159 0.064
maintenance of protein location GO:0045185 53 0.063
regulation of signal transduction GO:0009966 114 0.063
dna conformation change GO:0071103 98 0.063
reproductive process in single celled organism GO:0022413 145 0.061
regulation of biological quality GO:0065008 391 0.059
regulation of macroautophagy GO:0016241 15 0.059
mitotic nuclear division GO:0007067 131 0.058
meiotic cell cycle phase transition GO:0044771 1 0.057
mitotic cytokinesis GO:0000281 58 0.057
rna 3 end processing GO:0031123 88 0.057
negative regulation of phosphate metabolic process GO:0045936 49 0.057
mitotic sister chromatid segregation GO:0000070 85 0.057
response to transition metal nanoparticle GO:1990267 16 0.054
multi organism cellular process GO:0044764 120 0.054
cellular response to dna damage stimulus GO:0006974 287 0.054
alpha amino acid biosynthetic process GO:1901607 91 0.053
regulation of cellular component organization GO:0051128 334 0.052
regulation of dna replication GO:0006275 51 0.050
negative regulation of cell cycle phase transition GO:1901988 59 0.050
negative regulation of phosphorylation GO:0042326 28 0.048
carbohydrate metabolic process GO:0005975 252 0.048
rna localization GO:0006403 112 0.046
septin cytoskeleton organization GO:0032185 27 0.046
alpha amino acid metabolic process GO:1901605 124 0.046
protein localization to organelle GO:0033365 337 0.046
sexual reproduction GO:0019953 216 0.045
response to external stimulus GO:0009605 158 0.045
septin ring organization GO:0031106 26 0.045
positive regulation of dna metabolic process GO:0051054 26 0.045
regulation of protein dephosphorylation GO:0035304 4 0.044
cellular response to oxidative stress GO:0034599 94 0.044
regulation of autophagy GO:0010506 18 0.043
positive regulation of biosynthetic process GO:0009891 336 0.043
signal transduction GO:0007165 208 0.043
chromosome localization GO:0050000 20 0.042
meiotic cell cycle process GO:1903046 229 0.041
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.041
regulation of chromatin organization GO:1902275 23 0.041
response to inorganic substance GO:0010035 47 0.041
spindle assembly GO:0051225 9 0.040
spindle pole body separation GO:0000073 13 0.040
negative regulation of cell cycle process GO:0010948 86 0.040
regulation of histone modification GO:0031056 18 0.040
positive regulation of cellular component organization GO:0051130 116 0.039
organophosphate metabolic process GO:0019637 597 0.039
dna packaging GO:0006323 55 0.039
positive regulation of organelle organization GO:0010638 85 0.039
regulation of cell communication GO:0010646 124 0.038
microtubule organizing center organization GO:0031023 33 0.038
nuclear division GO:0000280 263 0.038
regulation of dephosphorylation GO:0035303 18 0.037
signaling GO:0023052 208 0.037
regulation of mitotic spindle organization GO:0060236 8 0.037
regulation of cellular response to stress GO:0080135 50 0.037
positive regulation of phosphate metabolic process GO:0045937 147 0.037
negative regulation of protein dephosphorylation GO:0035308 2 0.037
positive regulation of cellular catabolic process GO:0031331 128 0.036
organelle fission GO:0048285 272 0.036
conjugation GO:0000746 107 0.036
nucleoside phosphate metabolic process GO:0006753 458 0.035
regulation of chromosome organization GO:0033044 66 0.034
organic acid metabolic process GO:0006082 352 0.034
cellular developmental process GO:0048869 191 0.034
carbohydrate derivative biosynthetic process GO:1901137 181 0.033
meiosis i GO:0007127 92 0.033
dephosphorylation GO:0016311 127 0.033
response to osmotic stress GO:0006970 83 0.033
protein dephosphorylation GO:0006470 40 0.033
negative regulation of phosphorus metabolic process GO:0010563 49 0.033
organelle localization GO:0051640 128 0.033
regulation of catabolic process GO:0009894 199 0.033
regulation of mitotic cell cycle phase transition GO:1901990 68 0.033
response to hypoxia GO:0001666 4 0.032
mating type switching GO:0007533 28 0.032
cellular protein complex assembly GO:0043623 209 0.032
microtubule based process GO:0007017 117 0.032
pigment biosynthetic process GO:0046148 22 0.031
response to toxic substance GO:0009636 9 0.031
cellular homeostasis GO:0019725 138 0.030
regulation of cellular catabolic process GO:0031329 195 0.030
cell cycle dna replication GO:0044786 36 0.030
regulation of cell cycle phase transition GO:1901987 70 0.030
response to acid chemical GO:0001101 19 0.030
protein complex disassembly GO:0043241 70 0.030
organelle assembly GO:0070925 118 0.029
regulation of meiosis GO:0040020 42 0.029
cellular response to iron ion GO:0071281 3 0.029
response to organic cyclic compound GO:0014070 1 0.029
pigment metabolic process GO:0042440 23 0.029
cytokinetic process GO:0032506 78 0.028
positive regulation of response to stimulus GO:0048584 37 0.028
dna dependent dna replication GO:0006261 115 0.028
cell cycle checkpoint GO:0000075 82 0.028
regulation of cell division GO:0051302 113 0.028
carboxylic acid metabolic process GO:0019752 338 0.028
regulation of spindle organization GO:0090224 8 0.028
carbohydrate derivative metabolic process GO:1901135 549 0.028
single organism signaling GO:0044700 208 0.028
chromosome segregation GO:0007059 159 0.028
negative regulation of protein metabolic process GO:0051248 85 0.028
nuclear export GO:0051168 124 0.027
positive regulation of protein metabolic process GO:0051247 93 0.027
cellular carbohydrate metabolic process GO:0044262 135 0.027
multi organism reproductive process GO:0044703 216 0.027
homeostatic process GO:0042592 227 0.027
multi organism process GO:0051704 233 0.026
positive regulation of mitotic cell cycle GO:0045931 16 0.026
response to pheromone GO:0019236 92 0.026
cell budding GO:0007114 48 0.026
anatomical structure development GO:0048856 160 0.026
regulation of chromosome segregation GO:0051983 44 0.026
cellular glucan metabolic process GO:0006073 44 0.026
carbohydrate biosynthetic process GO:0016051 82 0.025
hexose metabolic process GO:0019318 78 0.025
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.025
carbohydrate catabolic process GO:0016052 77 0.025
regulation of mitotic spindle elongation GO:0032888 3 0.025
positive regulation of catabolic process GO:0009896 135 0.025
nucleobase biosynthetic process GO:0046112 17 0.025
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.024
chromatin silencing at silent mating type cassette GO:0030466 53 0.024
positive regulation of molecular function GO:0044093 185 0.024
maintenance of location GO:0051235 66 0.023
cell differentiation GO:0030154 161 0.023
protein modification by small protein conjugation or removal GO:0070647 172 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.023
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.023
translation GO:0006412 230 0.022
fungal type cell wall biogenesis GO:0009272 80 0.022
organophosphate biosynthetic process GO:0090407 182 0.022
cellular response to pheromone GO:0071444 88 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.022
organic anion transport GO:0015711 114 0.022
aromatic compound catabolic process GO:0019439 491 0.022
meiotic nuclear division GO:0007126 163 0.022
nucleocytoplasmic transport GO:0006913 163 0.022
regulation of microtubule cytoskeleton organization GO:0070507 32 0.021
histone modification GO:0016570 119 0.021
meiotic cell cycle GO:0051321 272 0.021
regulation of nuclear division GO:0051783 103 0.021
negative regulation of mitotic cell cycle GO:0045930 63 0.021
negative regulation of chromatin silencing GO:0031936 25 0.021
nucleotide biosynthetic process GO:0009165 79 0.021
glycogen metabolic process GO:0005977 30 0.020
microtubule polymerization GO:0046785 30 0.020
carboxylic acid biosynthetic process GO:0046394 152 0.020
cellular response to oxygen containing compound GO:1901701 43 0.020
cellular component morphogenesis GO:0032989 97 0.020
maturation of 5 8s rrna GO:0000460 80 0.020
nuclear transport GO:0051169 165 0.020
cell aging GO:0007569 70 0.020
response to oxidative stress GO:0006979 99 0.020
budding cell bud growth GO:0007117 29 0.020
cellular response to hypoxia GO:0071456 4 0.020
positive regulation of intracellular transport GO:0032388 4 0.020
regulation of spindle elongation GO:0032887 3 0.020
cellular response to starvation GO:0009267 90 0.019
re entry into mitotic cell cycle after pheromone arrest GO:0000321 9 0.019
generation of precursor metabolites and energy GO:0006091 147 0.019
single organism reproductive process GO:0044702 159 0.019
positive regulation of cell cycle process GO:0090068 31 0.019
ion homeostasis GO:0050801 118 0.019
glucose metabolic process GO:0006006 65 0.019
macromolecule methylation GO:0043414 85 0.019
ras protein signal transduction GO:0007265 29 0.019
positive regulation of intracellular protein transport GO:0090316 3 0.018
regulation of meiotic cell cycle GO:0051445 43 0.018
mating type determination GO:0007531 32 0.018
organic cyclic compound catabolic process GO:1901361 499 0.018
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.018
positive regulation of dna replication GO:0045740 11 0.018
nucleotide metabolic process GO:0009117 453 0.018
developmental process involved in reproduction GO:0003006 159 0.018
negative regulation of cytoskeleton organization GO:0051494 24 0.018
nitrogen compound transport GO:0071705 212 0.018
nuclear dna replication GO:0033260 27 0.017
nucleoside triphosphate metabolic process GO:0009141 364 0.017
purine nucleobase metabolic process GO:0006144 11 0.017
response to iron ion GO:0010039 3 0.017
oxidation reduction process GO:0055114 353 0.017
positive regulation of cellular protein metabolic process GO:0032270 89 0.017
positive regulation of cell cycle GO:0045787 32 0.017
rna phosphodiester bond hydrolysis GO:0090501 112 0.017
dna templated transcription termination GO:0006353 42 0.017
regulation of gene expression epigenetic GO:0040029 147 0.017
dna recombination GO:0006310 172 0.017
response to oxygen containing compound GO:1901700 61 0.017
cell wall biogenesis GO:0042546 93 0.017
energy reserve metabolic process GO:0006112 32 0.016
chromatin silencing GO:0006342 147 0.016
pyrimidine containing compound metabolic process GO:0072527 37 0.016
regulation of generation of precursor metabolites and energy GO:0043467 23 0.016
trna metabolic process GO:0006399 151 0.016
developmental growth GO:0048589 3 0.016
regulation of signaling GO:0023051 119 0.016
amino sugar biosynthetic process GO:0046349 17 0.016
positive regulation of protein modification process GO:0031401 49 0.015
cellular chemical homeostasis GO:0055082 123 0.015
posttranscriptional regulation of gene expression GO:0010608 115 0.015
regulation of microtubule based process GO:0032886 32 0.015
regulation of metal ion transport GO:0010959 2 0.015
cell wall organization or biogenesis GO:0071554 190 0.015
covalent chromatin modification GO:0016569 119 0.015
mitotic cytokinetic process GO:1902410 45 0.015
nucleobase containing small molecule metabolic process GO:0055086 491 0.015
regulation of gene silencing GO:0060968 41 0.015
negative regulation of organelle organization GO:0010639 103 0.015
positive regulation of response to nutrient levels GO:0032109 12 0.015
regulation of dna recombination GO:0000018 24 0.015
vacuole organization GO:0007033 75 0.015
gene silencing GO:0016458 151 0.015
metal ion homeostasis GO:0055065 79 0.014
regulation of translation GO:0006417 89 0.014
cytokinesis site selection GO:0007105 40 0.014
polysaccharide biosynthetic process GO:0000271 39 0.014
response to drug GO:0042493 41 0.014
regulation of dna templated transcription in response to stress GO:0043620 51 0.014
sex determination GO:0007530 32 0.014
regulation of ras protein signal transduction GO:0046578 47 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.014
regulation of cell differentiation GO:0045595 12 0.014
negative regulation of protein modification process GO:0031400 37 0.014
negative regulation of pseudohyphal growth GO:2000221 8 0.014
cellular metal ion homeostasis GO:0006875 78 0.014
methylation GO:0032259 101 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.014
cellular lipid metabolic process GO:0044255 229 0.014
cellular protein complex disassembly GO:0043624 42 0.014
regulation of cellular component biogenesis GO:0044087 112 0.013
response to metal ion GO:0010038 24 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.013
positive regulation of cytoplasmic transport GO:1903651 4 0.013
regulation of lipid catabolic process GO:0050994 4 0.013
carboxylic acid catabolic process GO:0046395 71 0.013
organonitrogen compound catabolic process GO:1901565 404 0.013
cation homeostasis GO:0055080 105 0.013
positive regulation of mrna processing GO:0050685 3 0.013
nucleoside phosphate catabolic process GO:1901292 331 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.013
peptidyl amino acid modification GO:0018193 116 0.013
histidine biosynthetic process GO:0000105 8 0.013
glucan metabolic process GO:0044042 44 0.013
regulation of localization GO:0032879 127 0.013
purine containing compound biosynthetic process GO:0072522 53 0.013
nucleobase metabolic process GO:0009112 22 0.013
protein modification by small protein conjugation GO:0032446 144 0.012
reciprocal meiotic recombination GO:0007131 54 0.012
amine metabolic process GO:0009308 51 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.012
cellular polysaccharide biosynthetic process GO:0033692 38 0.012
maintenance of dna repeat elements GO:0043570 20 0.012
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.012
non recombinational repair GO:0000726 33 0.012
positive regulation of cell communication GO:0010647 28 0.012
regulation of pseudohyphal growth GO:2000220 18 0.012
histone phosphorylation GO:0016572 3 0.012
nucleoside monophosphate metabolic process GO:0009123 267 0.012
cellular response to osmotic stress GO:0071470 50 0.012
cellular response to heat GO:0034605 53 0.012
cellular response to inorganic substance GO:0071241 11 0.012
dna replication initiation GO:0006270 48 0.012
cellular amine metabolic process GO:0044106 51 0.012
lipid catabolic process GO:0016042 33 0.012
regulation of cellular amino acid metabolic process GO:0006521 16 0.012
monosaccharide metabolic process GO:0005996 83 0.012
cellular carbohydrate biosynthetic process GO:0034637 49 0.011
protein polymerization GO:0051258 51 0.011
negative regulation of cell division GO:0051782 66 0.011
metaphase plate congression GO:0051310 8 0.011
negative regulation of growth of unicellular organism as a thread of attached cells GO:0070785 11 0.011
positive regulation of translation GO:0045727 34 0.011
positive regulation of lipid catabolic process GO:0050996 4 0.011
establishment of cell polarity GO:0030010 64 0.011
mitotic spindle elongation GO:0000022 14 0.011
ribosome biogenesis GO:0042254 335 0.011
lipid localization GO:0010876 60 0.011
negative regulation of chromatin silencing at silent mating type cassette GO:0061186 11 0.011
rrna processing GO:0006364 227 0.011
regulation of ribosomal protein gene transcription from rna polymerase ii promoter GO:0060962 10 0.011
mitotic spindle organization GO:0007052 30 0.011
positive regulation of mrna metabolic process GO:1903313 7 0.011
regulation of response to stress GO:0080134 57 0.011
positive regulation of cell death GO:0010942 3 0.011
establishment of protein localization GO:0045184 367 0.010
protein depolymerization GO:0051261 21 0.010
fungal type cell wall organization or biogenesis GO:0071852 169 0.010
filamentous growth GO:0030447 124 0.010
cellular polysaccharide metabolic process GO:0044264 55 0.010
aging GO:0007568 71 0.010
cellular bud site selection GO:0000282 35 0.010
synaptonemal complex assembly GO:0007130 12 0.010
polysaccharide metabolic process GO:0005976 60 0.010
macromolecular complex disassembly GO:0032984 80 0.010
regulation of protein depolymerization GO:1901879 12 0.010
regulation of fatty acid beta oxidation GO:0031998 3 0.010

CLN1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012