Saccharomyces cerevisiae

40 known processes

TIM44 (YIL022W)

Tim44p

(Aliases: MPI1,MIM44,ISP45)

TIM44 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of protein localization to mitochondrion GO:0072655 63 1.000
protein import into mitochondrial matrix GO:0030150 20 1.000
protein localization to mitochondrion GO:0070585 63 1.000
protein targeting to mitochondrion GO:0006626 56 1.000
protein transmembrane transport GO:0071806 82 1.000
intracellular protein transmembrane transport GO:0065002 80 1.000
mitochondrial transport GO:0006839 76 0.999
protein import GO:0017038 122 0.998
transmembrane transport GO:0055085 349 0.998
intracellular protein transmembrane import GO:0044743 67 0.990
protein targeting GO:0006605 272 0.990
protein transport GO:0015031 345 0.978
intracellular protein transport GO:0006886 319 0.977
mitochondrion organization GO:0007005 261 0.969
establishment of protein localization to organelle GO:0072594 278 0.969
single organism cellular localization GO:1902580 375 0.968
establishment of protein localization GO:0045184 367 0.959
protein localization to organelle GO:0033365 337 0.906
electron transport chain GO:0022900 25 0.290
protein folding GO:0006457 94 0.281
mitochondrial genome maintenance GO:0000002 40 0.245
iron sulfur cluster assembly GO:0016226 22 0.239
purine ribonucleoside metabolic process GO:0046128 380 0.212
purine nucleoside metabolic process GO:0042278 380 0.208
negative regulation of cellular metabolic process GO:0031324 407 0.193
cell communication GO:0007154 345 0.164
metallo sulfur cluster assembly GO:0031163 22 0.162
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.156
ribonucleoside metabolic process GO:0009119 389 0.136
oxidation reduction process GO:0055114 353 0.126
cytoskeleton organization GO:0007010 230 0.114
regulation of molecular function GO:0065009 320 0.111
rna modification GO:0009451 99 0.105
nucleoside metabolic process GO:0009116 394 0.103
phosphorylation GO:0016310 291 0.101
macromolecule catabolic process GO:0009057 383 0.101
heterocycle catabolic process GO:0046700 494 0.100
oxidative phosphorylation GO:0006119 26 0.098
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.096
nucleobase containing small molecule metabolic process GO:0055086 491 0.096
aromatic compound catabolic process GO:0019439 491 0.095
glycosyl compound metabolic process GO:1901657 398 0.095
organic cyclic compound catabolic process GO:1901361 499 0.093
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.090
regulation of biological quality GO:0065008 391 0.089
ribonucleoside triphosphate metabolic process GO:0009199 356 0.084
organophosphate metabolic process GO:0019637 597 0.083
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.080
purine containing compound metabolic process GO:0072521 400 0.079
cellular macromolecule catabolic process GO:0044265 363 0.078
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.077
ribonucleotide metabolic process GO:0009259 377 0.077
homeostatic process GO:0042592 227 0.076
nucleoside triphosphate metabolic process GO:0009141 364 0.076
ribonucleoprotein complex assembly GO:0022618 143 0.075
atp synthesis coupled electron transport GO:0042773 25 0.075
purine nucleoside triphosphate metabolic process GO:0009144 356 0.074
protein complex assembly GO:0006461 302 0.073
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.072
cellular nitrogen compound catabolic process GO:0044270 494 0.071
regulation of catalytic activity GO:0050790 307 0.070
negative regulation of phosphorus metabolic process GO:0010563 49 0.068
mitochondrial membrane organization GO:0007006 48 0.068
negative regulation of gene expression GO:0010629 312 0.066
purine ribonucleotide metabolic process GO:0009150 372 0.064
protein complex biogenesis GO:0070271 314 0.064
ncrna processing GO:0034470 330 0.063
atp metabolic process GO:0046034 251 0.063
nuclear export GO:0051168 124 0.063
negative regulation of phosphate metabolic process GO:0045936 49 0.062
chemical homeostasis GO:0048878 137 0.062
cellular chemical homeostasis GO:0055082 123 0.062
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.061
regulation of cellular component biogenesis GO:0044087 112 0.059
negative regulation of cellular biosynthetic process GO:0031327 312 0.058
ribonucleoprotein complex subunit organization GO:0071826 152 0.058
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.057
generation of precursor metabolites and energy GO:0006091 147 0.056
rna phosphodiester bond hydrolysis GO:0090501 112 0.056
metal ion homeostasis GO:0055065 79 0.056
regulation of phosphorylation GO:0042325 86 0.055
purine nucleotide metabolic process GO:0006163 376 0.055
nucleobase containing compound catabolic process GO:0034655 479 0.054
regulation of dna metabolic process GO:0051052 100 0.053
protein export from nucleus GO:0006611 17 0.053
protein refolding GO:0042026 16 0.052
nucleocytoplasmic transport GO:0006913 163 0.051
regulation of protein complex assembly GO:0043254 77 0.051
response to nutrient levels GO:0031667 150 0.051
protein modification by small protein conjugation GO:0032446 144 0.051
glycerolipid metabolic process GO:0046486 108 0.051
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.051
rrna processing GO:0006364 227 0.050
nucleotide metabolic process GO:0009117 453 0.050
mitotic cell cycle GO:0000278 306 0.050
nucleoside monophosphate metabolic process GO:0009123 267 0.050
signal transduction GO:0007165 208 0.049
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.049
protein ubiquitination GO:0016567 118 0.049
response to extracellular stimulus GO:0009991 156 0.048
organelle assembly GO:0070925 118 0.048
nucleoside phosphate metabolic process GO:0006753 458 0.047
dna catabolic process GO:0006308 42 0.047
organelle localization GO:0051640 128 0.046
regulation of nucleoside metabolic process GO:0009118 106 0.046
ribonucleoside monophosphate metabolic process GO:0009161 265 0.046
nuclear transcribed mrna catabolic process GO:0000956 89 0.044
phospholipid biosynthetic process GO:0008654 89 0.044
ion transport GO:0006811 274 0.044
cellular protein complex assembly GO:0043623 209 0.044
single organism catabolic process GO:0044712 619 0.044
cation homeostasis GO:0055080 105 0.044
trna transport GO:0051031 19 0.044
negative regulation of nucleic acid templated transcription GO:1903507 260 0.044
cellular cation homeostasis GO:0030003 100 0.043
organic anion transport GO:0015711 114 0.043
regulation of phosphate metabolic process GO:0019220 230 0.043
cellular response to extracellular stimulus GO:0031668 150 0.043
cellular ion homeostasis GO:0006873 112 0.042
transition metal ion homeostasis GO:0055076 59 0.042
negative regulation of signal transduction GO:0009968 30 0.040
positive regulation of macromolecule metabolic process GO:0010604 394 0.040
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000479 47 0.040
endonucleolytic cleavage involved in rrna processing GO:0000478 47 0.039
anatomical structure development GO:0048856 160 0.039
response to chemical GO:0042221 390 0.039
cellular homeostasis GO:0019725 138 0.039
glycerolipid biosynthetic process GO:0045017 71 0.038
protein phosphorylation GO:0006468 197 0.037
cellular response to starvation GO:0009267 90 0.037
phospholipid metabolic process GO:0006644 125 0.037
ribosomal small subunit biogenesis GO:0042274 124 0.036
positive regulation of molecular function GO:0044093 185 0.035
regulation of cellular component organization GO:0051128 334 0.035
negative regulation of cellular component organization GO:0051129 109 0.035
proteolysis GO:0006508 268 0.035
glycerophospholipid biosynthetic process GO:0046474 68 0.035
cellular iron ion homeostasis GO:0006879 34 0.034
regulation of nucleotide metabolic process GO:0006140 110 0.034
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.034
negative regulation of biosynthetic process GO:0009890 312 0.034
regulation of lipid metabolic process GO:0019216 45 0.034
cellular transition metal ion homeostasis GO:0046916 59 0.034
regulation of cellular catabolic process GO:0031329 195 0.034
response to organic cyclic compound GO:0014070 1 0.033
organonitrogen compound biosynthetic process GO:1901566 314 0.033
positive regulation of hydrolase activity GO:0051345 112 0.033
single organism signaling GO:0044700 208 0.033
carboxylic acid transport GO:0046942 74 0.032
ion homeostasis GO:0050801 118 0.032
response to organic substance GO:0010033 182 0.032
lipid biosynthetic process GO:0008610 170 0.032
carbohydrate derivative metabolic process GO:1901135 549 0.032
trna processing GO:0008033 101 0.032
regulation of response to stimulus GO:0048583 157 0.032
cellular response to dna damage stimulus GO:0006974 287 0.032
nuclear transport GO:0051169 165 0.031
iron ion homeostasis GO:0055072 34 0.031
cellular response to organic substance GO:0071310 159 0.031
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.031
response to external stimulus GO:0009605 158 0.031
nitrogen compound transport GO:0071705 212 0.031
protein maturation GO:0051604 76 0.031
amino acid transport GO:0006865 45 0.030
cellular component morphogenesis GO:0032989 97 0.030
developmental process GO:0032502 261 0.030
mitotic cell cycle process GO:1903047 294 0.030
vesicle mediated transport GO:0016192 335 0.030
maturation of ssu rrna GO:0030490 105 0.030
regulation of signaling GO:0023051 119 0.030
cleavage involved in rrna processing GO:0000469 69 0.030
response to starvation GO:0042594 96 0.030
methylation GO:0032259 101 0.029
organic acid transport GO:0015849 77 0.029
negative regulation of macromolecule metabolic process GO:0010605 375 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.029
positive regulation of catabolic process GO:0009896 135 0.029
negative regulation of protein complex assembly GO:0031333 15 0.029
trna modification GO:0006400 75 0.029
endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000447 43 0.028
regulation of organelle organization GO:0033043 243 0.028
growth GO:0040007 157 0.028
rrna metabolic process GO:0016072 244 0.027
protein modification by small protein conjugation or removal GO:0070647 172 0.027
regulation of generation of precursor metabolites and energy GO:0043467 23 0.027
autophagy GO:0006914 106 0.027
regulation of hydrolase activity GO:0051336 133 0.026
glycerophospholipid metabolic process GO:0006650 98 0.026
ribosome assembly GO:0042255 57 0.026
trna metabolic process GO:0006399 151 0.026
negative regulation of rna biosynthetic process GO:1902679 260 0.026
negative regulation of cellular protein metabolic process GO:0032269 85 0.025
regulation of transferase activity GO:0051338 83 0.025
maturation of 5 8s rrna GO:0000460 80 0.025
nucleobase containing compound transport GO:0015931 124 0.025
single organism membrane organization GO:0044802 275 0.025
cellular response to chemical stimulus GO:0070887 315 0.025
rna localization GO:0006403 112 0.024
modification dependent protein catabolic process GO:0019941 181 0.023
peptidyl amino acid modification GO:0018193 116 0.023
organic acid biosynthetic process GO:0016053 152 0.023
trna wobble base modification GO:0002097 27 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
membrane lipid biosynthetic process GO:0046467 54 0.023
regulation of catabolic process GO:0009894 199 0.023
positive regulation of rna metabolic process GO:0051254 294 0.022
cell cycle phase transition GO:0044770 144 0.022
microtubule cytoskeleton organization GO:0000226 109 0.022
cell cycle checkpoint GO:0000075 82 0.022
signaling GO:0023052 208 0.022
sphingolipid metabolic process GO:0006665 41 0.022
lipid metabolic process GO:0006629 269 0.022
cation transport GO:0006812 166 0.022
positive regulation of rna biosynthetic process GO:1902680 286 0.022
aerobic respiration GO:0009060 55 0.021
negative regulation of rna metabolic process GO:0051253 262 0.021
mrna catabolic process GO:0006402 93 0.021
mitotic cell cycle phase transition GO:0044772 141 0.021
anion transport GO:0006820 145 0.021
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 96 0.021
translation GO:0006412 230 0.021
ubiquitin dependent protein catabolic process GO:0006511 181 0.021
cell wall organization or biogenesis GO:0071554 190 0.021
cellular developmental process GO:0048869 191 0.021
single organism developmental process GO:0044767 258 0.020
sexual reproduction GO:0019953 216 0.020
negative regulation of transcription dna templated GO:0045892 258 0.019
fungal type cell wall organization or biogenesis GO:0071852 169 0.019
regulation of protein metabolic process GO:0051246 237 0.019
nucleic acid transport GO:0050657 94 0.019
ribosome biogenesis GO:0042254 335 0.019
rrna modification GO:0000154 19 0.019
rna transport GO:0050658 92 0.019
coenzyme metabolic process GO:0006732 104 0.019
regulation of translation GO:0006417 89 0.019
cellular lipid metabolic process GO:0044255 229 0.019
regulation of signal transduction GO:0009966 114 0.019
positive regulation of transcription dna templated GO:0045893 286 0.019
anatomical structure morphogenesis GO:0009653 160 0.019
regulation of kinase activity GO:0043549 71 0.018
membrane lipid metabolic process GO:0006643 67 0.018
hydrogen transport GO:0006818 61 0.018
endosomal transport GO:0016197 86 0.018
cellular ketone metabolic process GO:0042180 63 0.018
response to toxic substance GO:0009636 9 0.018
membrane organization GO:0061024 276 0.018
peptidyl lysine modification GO:0018205 77 0.018
positive regulation of programmed cell death GO:0043068 3 0.018
protein import into mitochondrial intermembrane space GO:0045041 7 0.018
cell division GO:0051301 205 0.017
vacuole organization GO:0007033 75 0.017
organophosphate biosynthetic process GO:0090407 182 0.017
spindle organization GO:0007051 37 0.017
cytokinetic process GO:0032506 78 0.017
regulation of cellular protein metabolic process GO:0032268 232 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.017
pseudouridine synthesis GO:0001522 13 0.017
cell surface receptor signaling pathway GO:0007166 38 0.017
rrna pseudouridine synthesis GO:0031118 4 0.017
chromatin organization GO:0006325 242 0.017
response to oxidative stress GO:0006979 99 0.017
amine metabolic process GO:0009308 51 0.017
developmental growth GO:0048589 3 0.017
reproductive process GO:0022414 248 0.017
trna wobble uridine modification GO:0002098 26 0.017
negative regulation of response to stimulus GO:0048585 40 0.017
regulation of protein modification process GO:0031399 110 0.017
monocarboxylic acid transport GO:0015718 24 0.016
proteasomal protein catabolic process GO:0010498 141 0.016
negative regulation of molecular function GO:0044092 68 0.016
ketone biosynthetic process GO:0042181 13 0.016
cellular amino acid metabolic process GO:0006520 225 0.016
positive regulation of biosynthetic process GO:0009891 336 0.016
ncrna 5 end processing GO:0034471 32 0.016
organophosphate catabolic process GO:0046434 338 0.016
serine family amino acid metabolic process GO:0009069 25 0.016
dna dependent dna replication GO:0006261 115 0.016
positive regulation of cell death GO:0010942 3 0.016
rna catabolic process GO:0006401 118 0.016
dna integrity checkpoint GO:0031570 41 0.015
establishment of rna localization GO:0051236 92 0.015
protein insertion into membrane from inner side GO:0032978 6 0.015
positive regulation of nucleic acid templated transcription GO:1903508 286 0.015
actin filament based process GO:0030029 104 0.015
positive regulation of apoptotic process GO:0043065 3 0.015
endomembrane system organization GO:0010256 74 0.015
rrna methylation GO:0031167 13 0.015
cellular component disassembly GO:0022411 86 0.015
regulation of cell cycle GO:0051726 195 0.015
protein import into mitochondrial outer membrane GO:0045040 9 0.015
purine nucleotide catabolic process GO:0006195 328 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.015
mitotic cytokinesis GO:0000281 58 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.015
rrna 5 end processing GO:0000967 32 0.015
regulation of protein kinase activity GO:0045859 67 0.015
purine ribonucleotide catabolic process GO:0009154 327 0.014
mitochondrion localization GO:0051646 29 0.014
g1 s transition of mitotic cell cycle GO:0000082 64 0.014
cellular amine metabolic process GO:0044106 51 0.014
multi organism reproductive process GO:0044703 216 0.014
cytoskeleton dependent cytokinesis GO:0061640 65 0.014
regulation of phosphorus metabolic process GO:0051174 230 0.014
alpha amino acid catabolic process GO:1901606 28 0.014
cellular modified amino acid metabolic process GO:0006575 51 0.014
positive regulation of phosphate metabolic process GO:0045937 147 0.014
positive regulation of dna metabolic process GO:0051054 26 0.014
organonitrogen compound catabolic process GO:1901565 404 0.014
rna splicing via transesterification reactions with guanosine as nucleophile GO:0000376 10 0.014
dna repair GO:0006281 236 0.014
regulation of cellular amino acid metabolic process GO:0006521 16 0.014
coenzyme biosynthetic process GO:0009108 66 0.014
negative regulation of transferase activity GO:0051348 31 0.013
gtp catabolic process GO:0006184 107 0.013
chromatin modification GO:0016568 200 0.013
iron ion transport GO:0006826 18 0.013
carboxylic acid biosynthetic process GO:0046394 152 0.013
regulation of mitotic cell cycle GO:0007346 107 0.013
organophosphate ester transport GO:0015748 45 0.013
rna 5 end processing GO:0000966 33 0.013
protein dephosphorylation GO:0006470 40 0.013
dephosphorylation GO:0016311 127 0.013
mitotic spindle organization GO:0007052 30 0.013
post golgi vesicle mediated transport GO:0006892 72 0.013
protein localization to membrane GO:0072657 102 0.013
microtubule based process GO:0007017 117 0.013
tetrapyrrole metabolic process GO:0033013 15 0.013
programmed cell death GO:0012501 30 0.013
negative regulation of signaling GO:0023057 30 0.013
nucleotide catabolic process GO:0009166 330 0.013
ribose phosphate metabolic process GO:0019693 384 0.013
telomere organization GO:0032200 75 0.013
conjugation with cellular fusion GO:0000747 106 0.013
negative regulation of organelle organization GO:0010639 103 0.012
negative regulation of cell communication GO:0010648 33 0.012
external encapsulating structure organization GO:0045229 146 0.012
regulation of protein phosphorylation GO:0001932 75 0.012
nucleoside catabolic process GO:0009164 335 0.012
aging GO:0007568 71 0.012
monocarboxylic acid metabolic process GO:0032787 122 0.012
negative regulation of cell cycle phase transition GO:1901988 59 0.012
regulation of cellular amine metabolic process GO:0033238 21 0.012
pyrimidine containing compound metabolic process GO:0072527 37 0.012
vacuolar transport GO:0007034 145 0.012
mitochondrial respiratory chain complex iv assembly GO:0033617 18 0.012
protein insertion into membrane GO:0051205 13 0.012
recombinational repair GO:0000725 64 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
negative regulation of intracellular signal transduction GO:1902532 27 0.012
negative regulation of cell cycle process GO:0010948 86 0.012
ribosomal large subunit assembly GO:0000027 35 0.011
establishment or maintenance of cell polarity GO:0007163 96 0.011
regulation of cell cycle phase transition GO:1901987 70 0.011
positive regulation of nucleoside metabolic process GO:0045979 97 0.011
actin filament organization GO:0007015 56 0.011
positive regulation of catalytic activity GO:0043085 178 0.011
regulation of transmembrane transporter activity GO:0022898 1 0.011
proton transport GO:0015992 61 0.011
dna strand elongation GO:0022616 29 0.011
response to topologically incorrect protein GO:0035966 38 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.011
peptidyl lysine acetylation GO:0018394 52 0.011
positive regulation of phosphorus metabolic process GO:0010562 147 0.011
protein dna complex assembly GO:0065004 105 0.011
purine nucleoside triphosphate catabolic process GO:0009146 329 0.011
positive regulation of cellular catabolic process GO:0031331 128 0.011
negative regulation of catabolic process GO:0009895 43 0.011
protein acetylation GO:0006473 59 0.011
chromosome segregation GO:0007059 159 0.011
negative regulation of catalytic activity GO:0043086 60 0.011
translational elongation GO:0006414 32 0.011
cytokinesis site selection GO:0007105 40 0.011
ribonucleoprotein complex localization GO:0071166 46 0.011
alpha amino acid biosynthetic process GO:1901607 91 0.011
establishment of ribosome localization GO:0033753 46 0.011
regulation of translational elongation GO:0006448 25 0.011
protein alkylation GO:0008213 48 0.011
regulation of cell division GO:0051302 113 0.011
internal peptidyl lysine acetylation GO:0018393 52 0.011
negative regulation of protein modification process GO:0031400 37 0.011
negative regulation of protein processing GO:0010955 33 0.011
regulation of metal ion transport GO:0010959 2 0.011
replicative cell aging GO:0001302 46 0.011
anatomical structure homeostasis GO:0060249 74 0.011
rna export from nucleus GO:0006405 88 0.011
nucleoside triphosphate catabolic process GO:0009143 329 0.011
positive regulation of protein metabolic process GO:0051247 93 0.011
meiotic cell cycle process GO:1903046 229 0.010
threonylcarbamoyladenosine metabolic process GO:0070525 9 0.010
pyridine containing compound metabolic process GO:0072524 53 0.010
cellular response to nutrient levels GO:0031669 144 0.010
ncrna 3 end processing GO:0043628 44 0.010
carbohydrate catabolic process GO:0016052 77 0.010
cellular biogenic amine metabolic process GO:0006576 37 0.010
response to abiotic stimulus GO:0009628 159 0.010
dna strand elongation involved in dna replication GO:0006271 26 0.010
positive regulation of gtp catabolic process GO:0033126 80 0.010
cellular amino acid catabolic process GO:0009063 48 0.010
negative regulation of phosphorylation GO:0042326 28 0.010
regulation of mitotic cell cycle phase transition GO:1901990 68 0.010
cellular metal ion homeostasis GO:0006875 78 0.010
pyridine nucleotide metabolic process GO:0019362 45 0.010
stress activated protein kinase signaling cascade GO:0031098 4 0.010
positive regulation of nucleotide metabolic process GO:0045981 101 0.010
protein n linked glycosylation GO:0006487 34 0.010
mrna metabolic process GO:0016071 269 0.010

TIM44 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016