Saccharomyces cerevisiae

20 known processes

SUL1 (YBR294W)

Sul1p

(Aliases: SFP2)

SUL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 352 0.417
oxoacid metabolic process GO:0043436 351 0.237
carboxylic acid metabolic process GO:0019752 338 0.157
serine family amino acid metabolic process GO:0009069 25 0.150
anion transport GO:0006820 145 0.135
small molecule biosynthetic process GO:0044283 258 0.125
transmembrane transport GO:0055085 349 0.120
ion transport GO:0006811 274 0.119
monocarboxylic acid metabolic process GO:0032787 122 0.115
vesicle mediated transport GO:0016192 335 0.100
cellular amino acid metabolic process GO:0006520 225 0.098
single organism catabolic process GO:0044712 619 0.096
cellular amino acid catabolic process GO:0009063 48 0.094
alpha amino acid biosynthetic process GO:1901607 91 0.093
alpha amino acid metabolic process GO:1901605 124 0.087
organonitrogen compound catabolic process GO:1901565 404 0.086
small molecule catabolic process GO:0044282 88 0.083
organic acid catabolic process GO:0016054 71 0.082
sulfur compound transport GO:0072348 19 0.070
cellular modified amino acid metabolic process GO:0006575 51 0.068
aspartate family amino acid biosynthetic process GO:0009067 29 0.064
carbohydrate metabolic process GO:0005975 252 0.061
carboxylic acid catabolic process GO:0046395 71 0.060
cellular lipid metabolic process GO:0044255 229 0.060
carbohydrate derivative metabolic process GO:1901135 549 0.056
methionine metabolic process GO:0006555 19 0.054
regulation of biological quality GO:0065008 391 0.050
Fly
single organism carbohydrate metabolic process GO:0044723 237 0.050
carboxylic acid biosynthetic process GO:0046394 152 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.046
regulation of cell cycle GO:0051726 195 0.045
sulfur compound metabolic process GO:0006790 95 0.043
alpha amino acid catabolic process GO:1901606 28 0.041
ribosome biogenesis GO:0042254 335 0.040
response to chemical GO:0042221 390 0.039
negative regulation of cellular metabolic process GO:0031324 407 0.039
positive regulation of macromolecule metabolic process GO:0010604 394 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.037
multi organism process GO:0051704 233 0.037
Fly
positive regulation of cellular biosynthetic process GO:0031328 336 0.037
lipid metabolic process GO:0006629 269 0.036
cellular amino acid biosynthetic process GO:0008652 118 0.036
sulfur amino acid metabolic process GO:0000096 34 0.035
nuclear division GO:0000280 263 0.035
organic acid transport GO:0015849 77 0.035
organelle fission GO:0048285 272 0.035
regulation of organelle organization GO:0033043 243 0.035
regulation of cell cycle process GO:0010564 150 0.034
organic cyclic compound catabolic process GO:1901361 499 0.033
response to organic substance GO:0010033 182 0.033
positive regulation of nucleic acid templated transcription GO:1903508 286 0.033
positive regulation of gene expression GO:0010628 321 0.033
negative regulation of macromolecule metabolic process GO:0010605 375 0.033
glycerolipid metabolic process GO:0046486 108 0.032
macromolecule catabolic process GO:0009057 383 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.032
positive regulation of biosynthetic process GO:0009891 336 0.032
carboxylic acid transport GO:0046942 74 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.031
negative regulation of biosynthetic process GO:0009890 312 0.031
organophosphate metabolic process GO:0019637 597 0.031
cellular macromolecule catabolic process GO:0044265 363 0.031
positive regulation of transcription dna templated GO:0045893 286 0.031
regulation of protein metabolic process GO:0051246 237 0.031
mitotic cell cycle GO:0000278 306 0.030
anatomical structure morphogenesis GO:0009653 160 0.030
rrna processing GO:0006364 227 0.030
single organism developmental process GO:0044767 258 0.030
cellular response to chemical stimulus GO:0070887 315 0.030
translation GO:0006412 230 0.030
cation transport GO:0006812 166 0.030
organic anion transport GO:0015711 114 0.030
rrna metabolic process GO:0016072 244 0.030
regulation of cellular component organization GO:0051128 334 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.030
nucleobase containing small molecule metabolic process GO:0055086 491 0.029
protein transport GO:0015031 345 0.029
organonitrogen compound biosynthetic process GO:1901566 314 0.029
reproductive process GO:0022414 248 0.029
Fly
sulfur compound biosynthetic process GO:0044272 53 0.029
cellular nitrogen compound catabolic process GO:0044270 494 0.029
homeostatic process GO:0042592 227 0.028
hexose metabolic process GO:0019318 78 0.028
aromatic compound catabolic process GO:0019439 491 0.028
purine containing compound metabolic process GO:0072521 400 0.028
establishment of protein localization to organelle GO:0072594 278 0.028
dna recombination GO:0006310 172 0.028
ion transmembrane transport GO:0034220 200 0.028
meiotic nuclear division GO:0007126 163 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.027
heterocycle catabolic process GO:0046700 494 0.027
ncrna processing GO:0034470 330 0.027
negative regulation of transcription dna templated GO:0045892 258 0.027
regulation of cellular protein metabolic process GO:0032268 232 0.027
detection of carbohydrate stimulus GO:0009730 3 0.027
monosaccharide metabolic process GO:0005996 83 0.027
nucleobase containing compound catabolic process GO:0034655 479 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.026
cell differentiation GO:0030154 161 0.026
negative regulation of cell cycle process GO:0010948 86 0.026
developmental process GO:0032502 261 0.026
protein complex assembly GO:0006461 302 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.025
meiotic cell cycle process GO:1903046 229 0.025
oxidation reduction process GO:0055114 353 0.025
regulation of phosphate metabolic process GO:0019220 230 0.025
meiotic cell cycle GO:0051321 272 0.025
mitotic cell cycle process GO:1903047 294 0.025
ribonucleoprotein complex assembly GO:0022618 143 0.025
sexual reproduction GO:0019953 216 0.024
Fly
negative regulation of rna biosynthetic process GO:1902679 260 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.024
protein localization to organelle GO:0033365 337 0.024
establishment of protein localization GO:0045184 367 0.024
regulation of nuclear division GO:0051783 103 0.024
cell communication GO:0007154 345 0.024
protein complex biogenesis GO:0070271 314 0.024
multi organism reproductive process GO:0044703 216 0.024
Fly
organelle localization GO:0051640 128 0.024
phosphorylation GO:0016310 291 0.023
cofactor metabolic process GO:0051186 126 0.023
regulation of catalytic activity GO:0050790 307 0.023
purine nucleoside metabolic process GO:0042278 380 0.023
glycosyl compound metabolic process GO:1901657 398 0.022
developmental process involved in reproduction GO:0003006 159 0.022
positive regulation of rna biosynthetic process GO:1902680 286 0.022
negative regulation of cellular biosynthetic process GO:0031327 312 0.022
cell division GO:0051301 205 0.022
anion transmembrane transport GO:0098656 79 0.022
regulation of molecular function GO:0065009 320 0.022
ribosomal small subunit biogenesis GO:0042274 124 0.022
macromolecule methylation GO:0043414 85 0.021
detection of monosaccharide stimulus GO:0034287 3 0.021
reproductive process in single celled organism GO:0022413 145 0.021
positive regulation of rna metabolic process GO:0051254 294 0.021
chemical homeostasis GO:0048878 137 0.021
nucleoside phosphate metabolic process GO:0006753 458 0.021
cell wall organization or biogenesis GO:0071554 190 0.021
nitrogen compound transport GO:0071705 212 0.021
regulation of protein modification process GO:0031399 110 0.021
cofactor biosynthetic process GO:0051188 80 0.020
single organism reproductive process GO:0044702 159 0.020
positive regulation of molecular function GO:0044093 185 0.020
ribonucleoprotein complex subunit organization GO:0071826 152 0.020
cellular amine metabolic process GO:0044106 51 0.020
regulation of cell division GO:0051302 113 0.020
anatomical structure development GO:0048856 160 0.020
mitochondrion organization GO:0007005 261 0.020
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.020
phospholipid metabolic process GO:0006644 125 0.020
negative regulation of nucleic acid templated transcription GO:1903507 260 0.020
negative regulation of cell cycle GO:0045786 91 0.020
nucleoside metabolic process GO:0009116 394 0.020
negative regulation of gene expression GO:0010629 312 0.020
detection of chemical stimulus GO:0009593 3 0.019
establishment of protein localization to vacuole GO:0072666 91 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.019
organelle assembly GO:0070925 118 0.019
cellular respiration GO:0045333 82 0.019
response to osmotic stress GO:0006970 83 0.019
detection of stimulus GO:0051606 4 0.019
response to organic cyclic compound GO:0014070 1 0.019
organic acid biosynthetic process GO:0016053 152 0.019
detection of glucose GO:0051594 3 0.019
vacuolar transport GO:0007034 145 0.019
coenzyme metabolic process GO:0006732 104 0.019
rna methylation GO:0001510 39 0.019
mrna metabolic process GO:0016071 269 0.018
purine nucleotide metabolic process GO:0006163 376 0.018
fungal type cell wall organization GO:0031505 145 0.018
nucleoside triphosphate metabolic process GO:0009141 364 0.018
cell development GO:0048468 107 0.018
chromosome segregation GO:0007059 159 0.018
positive regulation of protein metabolic process GO:0051247 93 0.018
endocytosis GO:0006897 90 0.018
glycerophospholipid metabolic process GO:0006650 98 0.018
cellular developmental process GO:0048869 191 0.018
sulfur compound catabolic process GO:0044273 12 0.018
response to extracellular stimulus GO:0009991 156 0.018
protein phosphorylation GO:0006468 197 0.018
purine ribonucleotide metabolic process GO:0009150 372 0.017
methylation GO:0032259 101 0.017
negative regulation of organelle organization GO:0010639 103 0.017
protein modification by small protein conjugation or removal GO:0070647 172 0.017
cellular component morphogenesis GO:0032989 97 0.017
carbohydrate biosynthetic process GO:0016051 82 0.017
nucleotide metabolic process GO:0009117 453 0.017
nuclear export GO:0051168 124 0.017
cell cycle phase transition GO:0044770 144 0.017
rna modification GO:0009451 99 0.017
organic hydroxy compound metabolic process GO:1901615 125 0.017
amine metabolic process GO:0009308 51 0.017
purine ribonucleoside metabolic process GO:0046128 380 0.017
ribonucleoside metabolic process GO:0009119 389 0.017
single organism cellular localization GO:1902580 375 0.017
cellular homeostasis GO:0019725 138 0.017
generation of precursor metabolites and energy GO:0006091 147 0.017
reproduction of a single celled organism GO:0032505 191 0.017
negative regulation of cellular component organization GO:0051129 109 0.017
dna replication GO:0006260 147 0.017
protein localization to vacuole GO:0072665 92 0.017
cell wall organization GO:0071555 146 0.017
glycosyl compound catabolic process GO:1901658 335 0.017
cellular response to dna damage stimulus GO:0006974 287 0.016
ribose phosphate metabolic process GO:0019693 384 0.016
positive regulation of apoptotic process GO:0043065 3 0.016
positive regulation of secretion GO:0051047 2 0.016
regulation of mitotic cell cycle GO:0007346 107 0.016
carbohydrate derivative biosynthetic process GO:1901137 181 0.016
regulation of catabolic process GO:0009894 199 0.016
signaling GO:0023052 208 0.016
regulation of phosphorus metabolic process GO:0051174 230 0.016
dephosphorylation GO:0016311 127 0.016
mitotic cell cycle phase transition GO:0044772 141 0.016
posttranscriptional regulation of gene expression GO:0010608 115 0.016
vacuole organization GO:0007033 75 0.016
purine containing compound catabolic process GO:0072523 332 0.016
positive regulation of catalytic activity GO:0043085 178 0.016
regulation of cellular ketone metabolic process GO:0010565 42 0.016
ribonucleotide catabolic process GO:0009261 327 0.016
negative regulation of rna metabolic process GO:0051253 262 0.016
positive regulation of cellular component organization GO:0051130 116 0.015
fatty acid metabolic process GO:0006631 51 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.015
regulation of translation GO:0006417 89 0.015
nucleocytoplasmic transport GO:0006913 163 0.015
organophosphate catabolic process GO:0046434 338 0.015
positive regulation of cell death GO:0010942 3 0.015
cellular response to organic substance GO:0071310 159 0.015
secretion GO:0046903 50 0.015
chromatin silencing GO:0006342 147 0.015
positive regulation of programmed cell death GO:0043068 3 0.015
sulfur amino acid biosynthetic process GO:0000097 19 0.015
single organism membrane organization GO:0044802 275 0.015
protein ubiquitination GO:0016567 118 0.015
dna dependent dna replication GO:0006261 115 0.015
anatomical structure formation involved in morphogenesis GO:0048646 136 0.015
regulation of response to stimulus GO:0048583 157 0.015
regulation of cellular component biogenesis GO:0044087 112 0.015
regulation of gene expression epigenetic GO:0040029 147 0.015
ribonucleoside catabolic process GO:0042454 332 0.015
single organism signaling GO:0044700 208 0.015
chromatin organization GO:0006325 242 0.015
conjugation with cellular fusion GO:0000747 106 0.015
membrane organization GO:0061024 276 0.015
carbohydrate derivative catabolic process GO:1901136 339 0.015
nucleotide catabolic process GO:0009166 330 0.015
cellular carbohydrate metabolic process GO:0044262 135 0.015
nucleoside phosphate catabolic process GO:1901292 331 0.015
protein modification by small protein conjugation GO:0032446 144 0.015
cellular protein catabolic process GO:0044257 213 0.015
regulation of meiosis GO:0040020 42 0.015
conjugation GO:0000746 107 0.014
dna conformation change GO:0071103 98 0.014
protein dna complex subunit organization GO:0071824 153 0.014
sexual sporulation GO:0034293 113 0.014
rna localization GO:0006403 112 0.014
regulation of meiotic cell cycle GO:0051445 43 0.014
cellular protein complex assembly GO:0043623 209 0.014
aerobic respiration GO:0009060 55 0.014
methionine biosynthetic process GO:0009086 16 0.014
regulation of dna metabolic process GO:0051052 100 0.014
nucleobase containing compound transport GO:0015931 124 0.014
signal transduction GO:0007165 208 0.014
sporulation resulting in formation of a cellular spore GO:0030435 129 0.014
negative regulation of nuclear division GO:0051784 62 0.014
positive regulation of secretion by cell GO:1903532 2 0.014
purine nucleoside catabolic process GO:0006152 330 0.014
external encapsulating structure organization GO:0045229 146 0.014
nuclear transport GO:0051169 165 0.014
carbohydrate catabolic process GO:0016052 77 0.014
detection of hexose stimulus GO:0009732 3 0.014
dna repair GO:0006281 236 0.014
response to abiotic stimulus GO:0009628 159 0.014
positive regulation of intracellular transport GO:0032388 4 0.014
nucleoside monophosphate metabolic process GO:0009123 267 0.014
establishment of organelle localization GO:0051656 96 0.014
purine ribonucleotide catabolic process GO:0009154 327 0.014
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.014
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 46 0.014
protein targeting to vacuole GO:0006623 91 0.013
regulation of cellular amine metabolic process GO:0033238 21 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.013
purine nucleoside monophosphate metabolic process GO:0009126 262 0.013
proteolysis GO:0006508 268 0.013
chromatin modification GO:0016568 200 0.013
regulation of cellular amino acid metabolic process GO:0006521 16 0.013
golgi vesicle transport GO:0048193 188 0.013
nucleoside triphosphate catabolic process GO:0009143 329 0.013
purine nucleoside triphosphate catabolic process GO:0009146 329 0.013
cellular component disassembly GO:0022411 86 0.013
spore wall assembly GO:0042244 52 0.013
glycosylation GO:0070085 66 0.013
ribonucleoside triphosphate metabolic process GO:0009199 356 0.013
intracellular protein transport GO:0006886 319 0.013
purine nucleotide catabolic process GO:0006195 328 0.013
regulation of protein complex assembly GO:0043254 77 0.013
reciprocal meiotic recombination GO:0007131 54 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.013
ribonucleoside triphosphate catabolic process GO:0009203 327 0.013
positive regulation of cellular protein metabolic process GO:0032270 89 0.013
mitotic nuclear division GO:0007067 131 0.013
ribonucleoprotein complex export from nucleus GO:0071426 46 0.013
organic hydroxy compound transport GO:0015850 41 0.013
energy derivation by oxidation of organic compounds GO:0015980 125 0.013
ribosome assembly GO:0042255 57 0.013
nucleoside catabolic process GO:0009164 335 0.013
ribonucleotide metabolic process GO:0009259 377 0.013
modification dependent protein catabolic process GO:0019941 181 0.013
response to nutrient levels GO:0031667 150 0.013
regulation of cell cycle phase transition GO:1901987 70 0.013
positive regulation of organelle organization GO:0010638 85 0.013
regulation of metal ion transport GO:0010959 2 0.013
alcohol metabolic process GO:0006066 112 0.013
organic hydroxy compound biosynthetic process GO:1901617 81 0.013
organophosphate biosynthetic process GO:0090407 182 0.013
regulation of signaling GO:0023051 119 0.013
regulation of cellular catabolic process GO:0031329 195 0.013
modification dependent macromolecule catabolic process GO:0043632 203 0.012
protein complex disassembly GO:0043241 70 0.012
inorganic anion transport GO:0015698 30 0.012
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.012
purine ribonucleoside catabolic process GO:0046130 330 0.012
regulation of mitotic cell cycle phase transition GO:1901990 68 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
rrna modification GO:0000154 19 0.012
protein targeting GO:0006605 272 0.012
amino acid transport GO:0006865 45 0.012
ion homeostasis GO:0050801 118 0.012
maintenance of location GO:0051235 66 0.012
establishment of ribosome localization GO:0033753 46 0.012
negative regulation of meiosis GO:0045835 23 0.012
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.012
chromosome organization involved in meiosis GO:0070192 32 0.012
cytoskeleton organization GO:0007010 230 0.012
response to hypoxia GO:0001666 4 0.012
phospholipid biosynthetic process GO:0008654 89 0.012
lipid transport GO:0006869 58 0.012
purine nucleoside triphosphate metabolic process GO:0009144 356 0.012
atp metabolic process GO:0046034 251 0.012
organelle inheritance GO:0048308 51 0.012
ribosomal subunit export from nucleus GO:0000054 46 0.012
sporulation GO:0043934 132 0.012
regulation of cellular component size GO:0032535 50 0.012
mannose transport GO:0015761 11 0.012
positive regulation of protein modification process GO:0031401 49 0.012
positive regulation of cytoplasmic transport GO:1903651 4 0.012
rna phosphodiester bond hydrolysis GO:0090501 112 0.012
ribonucleoside monophosphate metabolic process GO:0009161 265 0.012
mitochondrial translation GO:0032543 52 0.012
glycoprotein biosynthetic process GO:0009101 61 0.012
ribonucleoprotein complex localization GO:0071166 46 0.012
negative regulation of meiotic cell cycle GO:0051447 24 0.012
cellular ketone metabolic process GO:0042180 63 0.012
lipid biosynthetic process GO:0008610 170 0.012
trna processing GO:0008033 101 0.012
multi organism cellular process GO:0044764 120 0.012
regulation of sodium ion transport GO:0002028 1 0.012
telomere organization GO:0032200 75 0.012
trna metabolic process GO:0006399 151 0.012
maturation of 5 8s rrna GO:0000460 80 0.012
maturation of ssu rrna GO:0030490 105 0.012
cellular chemical homeostasis GO:0055082 123 0.012
cellular cation homeostasis GO:0030003 100 0.011
gene silencing GO:0016458 151 0.011
cellular response to abiotic stimulus GO:0071214 62 0.011
sister chromatid segregation GO:0000819 93 0.011
rna catabolic process GO:0006401 118 0.011
endosomal transport GO:0016197 86 0.011
plasma membrane selenite transport GO:0097080 3 0.011
regulation of localization GO:0032879 127 0.011
g1 s transition of mitotic cell cycle GO:0000082 64 0.011
translational initiation GO:0006413 56 0.011
protein maturation GO:0051604 76 0.011
fungal type cell wall assembly GO:0071940 53 0.011
regulation of hydrolase activity GO:0051336 133 0.011
growth GO:0040007 157 0.011
rrna methylation GO:0031167 13 0.011
macromolecule glycosylation GO:0043413 57 0.011
peptidyl amino acid modification GO:0018193 116 0.011
purine nucleoside monophosphate catabolic process GO:0009128 224 0.011
regulation of signal transduction GO:0009966 114 0.011
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 96 0.011
response to heat GO:0009408 69 0.011
regulation of dna templated transcription in response to stress GO:0043620 51 0.011
cell cycle checkpoint GO:0000075 82 0.011
ascospore formation GO:0030437 107 0.011
fungal type cell wall organization or biogenesis GO:0071852 169 0.011
mitotic recombination GO:0006312 55 0.011
aspartate family amino acid metabolic process GO:0009066 40 0.011
meiosis i GO:0007127 92 0.011
response to uv GO:0009411 4 0.011
cellular response to nutrient levels GO:0031669 144 0.011
macromolecular complex disassembly GO:0032984 80 0.011
glycerolipid biosynthetic process GO:0045017 71 0.011
positive regulation of phosphate metabolic process GO:0045937 147 0.011
oligosaccharide metabolic process GO:0009311 35 0.011
cell growth GO:0016049 89 0.011
protein folding GO:0006457 94 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
single organism carbohydrate catabolic process GO:0044724 73 0.011
negative regulation of gene expression epigenetic GO:0045814 147 0.011
protein localization to membrane GO:0072657 102 0.011
cytoplasmic translation GO:0002181 65 0.011
rna export from nucleus GO:0006405 88 0.011
post golgi vesicle mediated transport GO:0006892 72 0.011
atp catabolic process GO:0006200 224 0.011
ribosome localization GO:0033750 46 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.011
response to oxidative stress GO:0006979 99 0.011
regulation of growth GO:0040008 50 0.011
secretion by cell GO:0032940 50 0.011
regulation of transferase activity GO:0051338 83 0.010
positive regulation of intracellular protein transport GO:0090316 3 0.010
protein dna complex assembly GO:0065004 105 0.010
microtubule based process GO:0007017 117 0.010
cellular response to oxidative stress GO:0034599 94 0.010
response to external stimulus GO:0009605 158 0.010
translational elongation GO:0006414 32 0.010
cation homeostasis GO:0055080 105 0.010
cellular response to external stimulus GO:0071496 150 0.010
protein catabolic process GO:0030163 221 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
cellular response to zinc ion starvation GO:0034224 3 0.010
ascospore wall assembly GO:0030476 52 0.010

SUL1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020