Saccharomyces cerevisiae

179 known processes

MSH2 (YOL090W)

Msh2p

(Aliases: PMS5)

MSH2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 236 0.994
cellular response to dna damage stimulus GO:0006974 287 0.970
meiotic mismatch repair GO:0000710 9 0.796
double strand break repair GO:0006302 105 0.778
Mouse
meiosis i GO:0007127 92 0.749
mitotic recombination GO:0006312 55 0.747
mismatch repair GO:0006298 14 0.631
dna catabolic process endonucleolytic GO:0000737 31 0.602
dna recombination GO:0006310 172 0.598
nuclear division GO:0000280 263 0.549
nucleotide excision repair GO:0006289 50 0.445
dna catabolic process GO:0006308 42 0.417
organic cyclic compound catabolic process GO:1901361 499 0.415
organelle fission GO:0048285 272 0.415
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.408
negative regulation of macromolecule metabolic process GO:0010605 375 0.389
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.380
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.372
meiotic nuclear division GO:0007126 163 0.354
meiotic cell cycle GO:0051321 272 0.346
heterocycle catabolic process GO:0046700 494 0.267
cell communication GO:0007154 345 0.262
Mouse Worm
mating type determination GO:0007531 32 0.251
mating type switching GO:0007533 28 0.246
organonitrogen compound biosynthetic process GO:1901566 314 0.240
maintenance of dna repeat elements GO:0043570 20 0.239
Human Zebrafish Worm
cellular macromolecule catabolic process GO:0044265 363 0.225
negative regulation of rna biosynthetic process GO:1902679 260 0.224
gene conversion at mating type locus GO:0007534 11 0.220
nucleobase containing compound catabolic process GO:0034655 479 0.220
regulation of dna metabolic process GO:0051052 100 0.214
Human Mouse
negative regulation of cellular metabolic process GO:0031324 407 0.195
regulation of biological quality GO:0065008 391 0.190
negative regulation of biosynthetic process GO:0009890 312 0.183
chromatin organization GO:0006325 242 0.181
aromatic compound catabolic process GO:0019439 491 0.179
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.176
organophosphate metabolic process GO:0019637 597 0.168
meiotic cell cycle process GO:1903046 229 0.166
single organism catabolic process GO:0044712 619 0.165
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.161
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.161
sex determination GO:0007530 32 0.145
cellular lipid metabolic process GO:0044255 229 0.142
positive regulation of macromolecule metabolic process GO:0010604 394 0.137
intracellular signal transduction GO:0035556 112 0.134
Mouse Worm
dna biosynthetic process GO:0071897 33 0.132
positive regulation of hydrolase activity GO:0051345 112 0.128
Human
ion homeostasis GO:0050801 118 0.127
reproduction of a single celled organism GO:0032505 191 0.125
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.122
developmental process involved in reproduction GO:0003006 159 0.121
cellular nitrogen compound catabolic process GO:0044270 494 0.119
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.113
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.113
regulation of response to stimulus GO:0048583 157 0.105
programmed cell death GO:0012501 30 0.103
Mouse Worm
death GO:0016265 30 0.099
Mouse Worm
regulation of protein metabolic process GO:0051246 237 0.097
signal transduction GO:0007165 208 0.095
Mouse Worm
reproductive process GO:0022414 248 0.094
nucleoside catabolic process GO:0009164 335 0.094
regulation of phosphate metabolic process GO:0019220 230 0.091
macromolecule catabolic process GO:0009057 383 0.087
non recombinational repair GO:0000726 33 0.085
carbohydrate metabolic process GO:0005975 252 0.082
positive regulation of molecular function GO:0044093 185 0.074
Human
positive regulation of catalytic activity GO:0043085 178 0.074
Human
carbohydrate derivative metabolic process GO:1901135 549 0.074
signaling GO:0023052 208 0.071
Mouse Worm
negative regulation of rna metabolic process GO:0051253 262 0.064
regulation of cellular catabolic process GO:0031329 195 0.064
response to abiotic stimulus GO:0009628 159 0.063
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 260 0.062
regulation of dna recombination GO:0000018 24 0.062
Human Mouse
purine nucleoside monophosphate metabolic process GO:0009126 262 0.062
negative regulation of cellular biosynthetic process GO:0031327 312 0.061
ribonucleoside monophosphate metabolic process GO:0009161 265 0.061
purine ribonucleoside metabolic process GO:0046128 380 0.060
single organism signaling GO:0044700 208 0.059
Mouse Worm
nucleoside phosphate metabolic process GO:0006753 458 0.059
mitotic cell cycle GO:0000278 306 0.059
Mouse
reciprocal meiotic recombination GO:0007131 54 0.056
negative regulation of gene expression GO:0010629 312 0.054
ion transport GO:0006811 274 0.052
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.051
apoptotic process GO:0006915 30 0.050
Mouse Worm
response to chemical GO:0042221 390 0.048
homeostatic process GO:0042592 227 0.048
gene silencing by rna GO:0031047 3 0.048
dna conformation change GO:0071103 98 0.048
regulation of molecular function GO:0065009 320 0.046
Human
regulation of hydrolase activity GO:0051336 133 0.045
Human
ribose phosphate metabolic process GO:0019693 384 0.044
nucleoside triphosphate metabolic process GO:0009141 364 0.044
cellular response to chemical stimulus GO:0070887 315 0.043
chromosome segregation GO:0007059 159 0.043
organophosphate catabolic process GO:0046434 338 0.042
regulation of transport GO:0051049 85 0.041
reciprocal dna recombination GO:0035825 54 0.041
negative regulation of transcription dna templated GO:0045892 258 0.038
glycosyl compound metabolic process GO:1901657 398 0.037
reproductive process in single celled organism GO:0022413 145 0.037
atp metabolic process GO:0046034 251 0.037
positive regulation of phosphorus metabolic process GO:0010562 147 0.036
mitotic cell cycle process GO:1903047 294 0.036
Mouse
nucleotide catabolic process GO:0009166 330 0.036
organic acid metabolic process GO:0006082 352 0.036
purine nucleotide metabolic process GO:0006163 376 0.035
lagging strand elongation GO:0006273 10 0.034
regulation of signal transduction GO:0009966 114 0.034
dna strand elongation GO:0022616 29 0.034
ribonucleoside metabolic process GO:0009119 389 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.033
purine nucleoside triphosphate metabolic process GO:0009144 356 0.033
regulation of localization GO:0032879 127 0.033
regulation of catalytic activity GO:0050790 307 0.032
Human
dna dependent dna replication GO:0006261 115 0.032
response to nutrient levels GO:0031667 150 0.031
gene conversion GO:0035822 14 0.029
purine nucleoside triphosphate catabolic process GO:0009146 329 0.029
response to external stimulus GO:0009605 158 0.028
purine nucleoside metabolic process GO:0042278 380 0.028
protein complex biogenesis GO:0070271 314 0.028
chemical homeostasis GO:0048878 137 0.027
dna replication GO:0006260 147 0.027
cellular amino acid metabolic process GO:0006520 225 0.026
regulation of organelle organization GO:0033043 243 0.026
cell differentiation GO:0030154 161 0.026
purine ribonucleoside catabolic process GO:0046130 330 0.025
cellular amine metabolic process GO:0044106 51 0.025
cellular homeostasis GO:0019725 138 0.024
posttranscriptional regulation of gene expression GO:0010608 115 0.024
translation GO:0006412 230 0.024
single organism developmental process GO:0044767 258 0.024
ribonucleotide metabolic process GO:0009259 377 0.023
cellular response to extracellular stimulus GO:0031668 150 0.023
ribonucleoside triphosphate metabolic process GO:0009199 356 0.023
regulation of cell communication GO:0010646 124 0.022
protein complex assembly GO:0006461 302 0.022
anatomical structure morphogenesis GO:0009653 160 0.022
regulation of cellular protein metabolic process GO:0032268 232 0.022
positive regulation of biosynthetic process GO:0009891 336 0.022
gene silencing GO:0016458 151 0.022
regulation of catabolic process GO:0009894 199 0.022
purine containing compound catabolic process GO:0072523 332 0.021
nucleoside monophosphate metabolic process GO:0009123 267 0.021
autophagy GO:0006914 106 0.021
nucleotide metabolic process GO:0009117 453 0.021
organonitrogen compound catabolic process GO:1901565 404 0.021
developmental process GO:0032502 261 0.019
organic anion transport GO:0015711 114 0.019
positive regulation of rna biosynthetic process GO:1902680 286 0.019
nucleobase containing small molecule metabolic process GO:0055086 491 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.019
positive regulation of catabolic process GO:0009896 135 0.018
small molecule biosynthetic process GO:0044283 258 0.018
protein modification by small protein conjugation or removal GO:0070647 172 0.018
atp catabolic process GO:0006200 224 0.017
response to oxygen containing compound GO:1901700 61 0.017
regulation of phosphorylation GO:0042325 86 0.017
cellular response to organic substance GO:0071310 159 0.017
establishment of organelle localization GO:0051656 96 0.016
regulation of phosphorus metabolic process GO:0051174 230 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.016
establishment of protein localization GO:0045184 367 0.016
regulation of intracellular signal transduction GO:1902531 78 0.016
cellular biogenic amine metabolic process GO:0006576 37 0.016
glycosyl compound catabolic process GO:1901658 335 0.015
purine containing compound metabolic process GO:0072521 400 0.015
purine ribonucleotide metabolic process GO:0009150 372 0.015
nucleoside triphosphate catabolic process GO:0009143 329 0.015
regulation of gene expression epigenetic GO:0040029 147 0.015
cellular response to external stimulus GO:0071496 150 0.015
phosphorylation GO:0016310 291 0.015
Mouse
dna replication okazaki fragment processing GO:0033567 7 0.015
positive regulation of apoptotic process GO:0043065 3 0.015
vesicle mediated transport GO:0016192 335 0.015
purine nucleoside monophosphate catabolic process GO:0009128 224 0.014
base excision repair GO:0006284 14 0.014
cellular protein complex assembly GO:0043623 209 0.014
cellular response to oxygen containing compound GO:1901701 43 0.014
covalent chromatin modification GO:0016569 119 0.014
positive regulation of dna metabolic process GO:0051054 26 0.013
response to uv GO:0009411 4 0.013
Mouse
positive regulation of rna metabolic process GO:0051254 294 0.013
response to oxidative stress GO:0006979 99 0.013
ribonucleotide catabolic process GO:0009261 327 0.013
positive regulation of cellular component organization GO:0051130 116 0.013
positive regulation of gene expression GO:0010628 321 0.013
telomere maintenance via recombination GO:0000722 32 0.013
nucleobase containing compound transport GO:0015931 124 0.013
dna packaging GO:0006323 55 0.013
ribonucleoside catabolic process GO:0042454 332 0.012
purine nucleotide catabolic process GO:0006195 328 0.012
regulation of signaling GO:0023051 119 0.012
cellular response to starvation GO:0009267 90 0.012
cell fate commitment GO:0045165 32 0.012
positive regulation of cellular catabolic process GO:0031331 128 0.012
regulation of protein modification process GO:0031399 110 0.011
purine ribonucleotide catabolic process GO:0009154 327 0.011
protein dna complex assembly GO:0065004 105 0.011
purine nucleoside catabolic process GO:0006152 330 0.011
metal ion homeostasis GO:0055065 79 0.011
response to extracellular stimulus GO:0009991 156 0.011
positive regulation of cellular biosynthetic process GO:0031328 336 0.011
regulation of cellular component biogenesis GO:0044087 112 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.011
positive regulation of nucleic acid templated transcription GO:1903508 286 0.011
chromatin modification GO:0016568 200 0.011
chromatin remodeling GO:0006338 80 0.010
positive regulation of protein modification process GO:0031401 49 0.010
cell wall organization or biogenesis GO:0071554 190 0.010

MSH2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.026