Saccharomyces cerevisiae

34 known processes

SMC6 (YLR383W)

Smc6p

(Aliases: RHC18)

SMC6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 236 0.996
cellular response to dna damage stimulus GO:0006974 287 0.995
double strand break repair GO:0006302 105 0.972
recombinational repair GO:0000725 64 0.961
telomere maintenance via recombination GO:0000722 32 0.832
Human
double strand break repair via homologous recombination GO:0000724 54 0.809
dna dependent dna replication GO:0006261 115 0.764
telomere maintenance GO:0000723 74 0.753
Human
mitotic recombination GO:0006312 55 0.719
Human
negative regulation of cellular metabolic process GO:0031324 407 0.643
anatomical structure homeostasis GO:0060249 74 0.637
Human
macromolecule catabolic process GO:0009057 383 0.578
cellular macromolecule catabolic process GO:0044265 363 0.535
homeostatic process GO:0042592 227 0.384
Human
chromosome segregation GO:0007059 159 0.364
telomere organization GO:0032200 75 0.362
Human
negative regulation of biosynthetic process GO:0009890 312 0.332
negative regulation of macromolecule metabolic process GO:0010605 375 0.326
mitotic cell cycle process GO:1903047 294 0.319
nucleobase containing small molecule metabolic process GO:0055086 491 0.303
mitotic cell cycle GO:0000278 306 0.291
mitotic cell cycle phase transition GO:0044772 141 0.261
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.259
postreplication repair GO:0006301 24 0.240
nucleobase containing compound catabolic process GO:0034655 479 0.229
dna recombination GO:0006310 172 0.226
dna replication GO:0006260 147 0.218
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.212
cell cycle phase transition GO:0044770 144 0.205
single organism catabolic process GO:0044712 619 0.178
modification dependent macromolecule catabolic process GO:0043632 203 0.177
ubiquitin dependent protein catabolic process GO:0006511 181 0.163
mitotic sister chromatid separation GO:0051306 26 0.157
nuclear division GO:0000280 263 0.154
mitotic sister chromatid cohesion GO:0007064 38 0.152
rna dependent dna replication GO:0006278 25 0.150
negative regulation of nuclear division GO:0051784 62 0.149
proteasomal protein catabolic process GO:0010498 141 0.142
telomere maintenance via telomerase GO:0007004 21 0.137
reciprocal dna recombination GO:0035825 54 0.136
metaphase anaphase transition of cell cycle GO:0044784 28 0.135
nucleoside triphosphate metabolic process GO:0009141 364 0.123
protein catabolic process GO:0030163 221 0.119
sister chromatid segregation GO:0000819 93 0.118
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.118
double strand break repair via break induced replication GO:0000727 25 0.115
regulation of mitotic sister chromatid separation GO:0010965 29 0.111
organophosphate metabolic process GO:0019637 597 0.106
negative regulation of cellular biosynthetic process GO:0031327 312 0.106
aromatic compound catabolic process GO:0019439 491 0.105
nucleoside metabolic process GO:0009116 394 0.105
modification dependent protein catabolic process GO:0019941 181 0.100
purine containing compound metabolic process GO:0072521 400 0.098
dna geometric change GO:0032392 43 0.096
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.096
meiosis i GO:0007127 92 0.095
cellular nitrogen compound catabolic process GO:0044270 494 0.094
regulation of cellular protein metabolic process GO:0032268 232 0.092
purine ribonucleotide metabolic process GO:0009150 372 0.092
regulation of cell cycle phase transition GO:1901987 70 0.091
meiotic cell cycle process GO:1903046 229 0.091
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.089
regulation of mitotic sister chromatid segregation GO:0033047 30 0.088
cellular protein catabolic process GO:0044257 213 0.088
regulation of dna metabolic process GO:0051052 100 0.087
regulation of chromosome organization GO:0033044 66 0.086
atp metabolic process GO:0046034 251 0.085
regulation of mitotic metaphase anaphase transition GO:0030071 27 0.085
cell communication GO:0007154 345 0.084
purine nucleoside monophosphate metabolic process GO:0009126 262 0.083
dna biosynthetic process GO:0071897 33 0.083
nucleoside monophosphate metabolic process GO:0009123 267 0.083
negative regulation of rna metabolic process GO:0051253 262 0.083
mitotic sister chromatid segregation GO:0000070 85 0.076
carbohydrate derivative metabolic process GO:1901135 549 0.072
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.071
nucleotide metabolic process GO:0009117 453 0.071
glycosyl compound metabolic process GO:1901657 398 0.069
purine containing compound catabolic process GO:0072523 332 0.068
non recombinational repair GO:0000726 33 0.067
regulation of metaphase anaphase transition of cell cycle GO:1902099 27 0.066
ribonucleoside monophosphate metabolic process GO:0009161 265 0.065
purine ribonucleoside metabolic process GO:0046128 380 0.064
chromosome condensation GO:0030261 19 0.064
meiotic mismatch repair GO:0000710 9 0.063
cell aging GO:0007569 70 0.062
Human
organelle assembly GO:0070925 118 0.061
telomere maintenance via telomere lengthening GO:0010833 22 0.061
regulation of cellular component organization GO:0051128 334 0.061
regulation of mitotic cell cycle phase transition GO:1901990 68 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.060
protein dna complex subunit organization GO:0071824 153 0.059
protein dna complex assembly GO:0065004 105 0.059
positive regulation of macromolecule metabolic process GO:0010604 394 0.057
organic cyclic compound catabolic process GO:1901361 499 0.057
reproduction of a single celled organism GO:0032505 191 0.056
heterocycle catabolic process GO:0046700 494 0.055
regulation of catabolic process GO:0009894 199 0.055
response to abiotic stimulus GO:0009628 159 0.055
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 23 0.054
negative regulation of cell division GO:0051782 66 0.054
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.052
regulation of biological quality GO:0065008 391 0.051
Human
ribose phosphate metabolic process GO:0019693 384 0.049
cell cycle checkpoint GO:0000075 82 0.049
dna conformation change GO:0071103 98 0.049
regulation of nuclear division GO:0051783 103 0.047
mitotic spindle assembly checkpoint GO:0007094 23 0.046
positive regulation of biosynthetic process GO:0009891 336 0.046
purine nucleoside catabolic process GO:0006152 330 0.046
positive regulation of gene expression GO:0010628 321 0.045
negative regulation of mitotic metaphase anaphase transition GO:0045841 23 0.044
positive regulation of cellular biosynthetic process GO:0031328 336 0.043
negative regulation of cell cycle process GO:0010948 86 0.043
negative regulation of mitotic sister chromatid separation GO:2000816 23 0.043
aging GO:0007568 71 0.042
Human
mismatch repair GO:0006298 14 0.042
nucleotide catabolic process GO:0009166 330 0.042
nucleoside catabolic process GO:0009164 335 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.042
developmental process GO:0032502 261 0.041
Human
negative regulation of dna metabolic process GO:0051053 36 0.041
glycosyl compound catabolic process GO:1901658 335 0.040
nucleoside phosphate metabolic process GO:0006753 458 0.040
nucleoside triphosphate catabolic process GO:0009143 329 0.039
organelle fission GO:0048285 272 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.039
nucleotide excision repair GO:0006289 50 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.038
purine nucleotide metabolic process GO:0006163 376 0.038
purine nucleoside monophosphate catabolic process GO:0009128 224 0.037
atp catabolic process GO:0006200 224 0.034
negative regulation of gene expression GO:0010629 312 0.033
negative regulation of nucleic acid templated transcription GO:1903507 260 0.033
dna strand elongation GO:0022616 29 0.033
hexose metabolic process GO:0019318 78 0.033
chromatin silencing GO:0006342 147 0.033
translesion synthesis GO:0019985 16 0.032
regulation of dna replication GO:0006275 51 0.032
dna replication removal of rna primer GO:0043137 5 0.032
single organism signaling GO:0044700 208 0.032
purine nucleoside metabolic process GO:0042278 380 0.032
organonitrogen compound catabolic process GO:1901565 404 0.031
negative regulation of cellular component organization GO:0051129 109 0.030
signal transduction GO:0007165 208 0.030
ribonucleoside catabolic process GO:0042454 332 0.030
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.030
developmental process involved in reproduction GO:0003006 159 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.030
ribonucleoside triphosphate catabolic process GO:0009203 327 0.029
regulation of cellular catabolic process GO:0031329 195 0.029
transposition GO:0032196 20 0.029
ribonucleoside monophosphate catabolic process GO:0009158 224 0.029
purine nucleoside triphosphate catabolic process GO:0009146 329 0.029
negative regulation of cell cycle phase transition GO:1901988 59 0.029
mitotic cell cycle checkpoint GO:0007093 56 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.028
dna catabolic process GO:0006308 42 0.028
regulation of dna dependent dna replication GO:0090329 37 0.028
carbohydrate derivative catabolic process GO:1901136 339 0.028
mitotic nuclear division GO:0007067 131 0.028
reciprocal meiotic recombination GO:0007131 54 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.028
positive regulation of protein metabolic process GO:0051247 93 0.026
regulation of sister chromatid segregation GO:0033045 30 0.026
organophosphate biosynthetic process GO:0090407 182 0.026
dna replication okazaki fragment processing GO:0033567 7 0.026
dna packaging GO:0006323 55 0.026
ribonucleoside metabolic process GO:0009119 389 0.025
chromatin organization GO:0006325 242 0.025
positive regulation of catabolic process GO:0009896 135 0.025
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.025
cell cycle g2 m phase transition GO:0044839 39 0.025
single organism reproductive process GO:0044702 159 0.024
rdna condensation GO:0070550 9 0.024
positive regulation of nucleic acid templated transcription GO:1903508 286 0.024
nucleoside phosphate catabolic process GO:1901292 331 0.024
regulation of hydrolase activity GO:0051336 133 0.023
purine ribonucleoside catabolic process GO:0046130 330 0.023
regulation of molecular function GO:0065009 320 0.023
double strand break repair via nonhomologous end joining GO:0006303 27 0.023
dna strand elongation involved in dna replication GO:0006271 26 0.022
regulation of cell division GO:0051302 113 0.022
regulation of mitotic cell cycle GO:0007346 107 0.022
sex determination GO:0007530 32 0.022
meiotic chromosome segregation GO:0045132 31 0.022
dna duplex unwinding GO:0032508 42 0.022
purine nucleotide catabolic process GO:0006195 328 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.022
nucleoside monophosphate catabolic process GO:0009125 224 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.021
purine ribonucleotide catabolic process GO:0009154 327 0.021
signaling GO:0023052 208 0.021
regulation of transposition GO:0010528 16 0.021
pseudohyphal growth GO:0007124 75 0.021
ribonucleotide metabolic process GO:0009259 377 0.021
reproductive process in single celled organism GO:0022413 145 0.020
regulation of cell cycle process GO:0010564 150 0.020
maintenance of dna repeat elements GO:0043570 20 0.019
purine nucleoside triphosphate metabolic process GO:0009144 356 0.019
regulation of organelle organization GO:0033043 243 0.019
meiotic nuclear division GO:0007126 163 0.019
protein localization to organelle GO:0033365 337 0.019
protein phosphorylation GO:0006468 197 0.019
cell division GO:0051301 205 0.019
ribonucleotide catabolic process GO:0009261 327 0.019
gene conversion GO:0035822 14 0.018
cell differentiation GO:0030154 161 0.018
mating type switching GO:0007533 28 0.018
organophosphate catabolic process GO:0046434 338 0.018
heterochromatin organization GO:0070828 11 0.018
chromosome separation GO:0051304 33 0.018
positive regulation of apoptotic process GO:0043065 3 0.018
proteolysis GO:0006508 268 0.018
gene conversion at mating type locus GO:0007534 11 0.018
phospholipid biosynthetic process GO:0008654 89 0.018
single organism developmental process GO:0044767 258 0.018
Human
dna double strand break processing GO:0000729 8 0.018
chromosome organization involved in meiosis GO:0070192 32 0.018
error prone translesion synthesis GO:0042276 11 0.018
organelle localization GO:0051640 128 0.017
organonitrogen compound biosynthetic process GO:1901566 314 0.017
nucleocytoplasmic transport GO:0006913 163 0.017
negative regulation of rna biosynthetic process GO:1902679 260 0.017
base excision repair GO:0006284 14 0.017
positive regulation of transcription dna templated GO:0045893 286 0.017
regulation of proteolysis GO:0030162 44 0.017
regulation of cell cycle GO:0051726 195 0.016
positive regulation of rna biosynthetic process GO:1902680 286 0.016
glycerophospholipid metabolic process GO:0006650 98 0.016
nuclear dna replication GO:0033260 27 0.016
sister chromatid cohesion GO:0007062 49 0.015
protein complex localization GO:0031503 32 0.015
cellular response to chemical stimulus GO:0070887 315 0.015
meiotic cell cycle GO:0051321 272 0.015
transposition rna mediated GO:0032197 17 0.015
anatomical structure morphogenesis GO:0009653 160 0.015
phosphorylation GO:0016310 291 0.015
negative regulation of organelle organization GO:0010639 103 0.015
negative regulation of mitotic sister chromatid segregation GO:0033048 24 0.015
negative regulation of chromosome segregation GO:0051985 25 0.015
error free translesion synthesis GO:0070987 9 0.015
negative regulation of dna replication GO:0008156 15 0.015
dna unwinding involved in dna replication GO:0006268 13 0.014
ribonucleoside triphosphate metabolic process GO:0009199 356 0.014
response to chemical GO:0042221 390 0.014
phospholipid metabolic process GO:0006644 125 0.014
regulation of protein processing GO:0070613 34 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.014
protein ubiquitination GO:0016567 118 0.014
single organism cellular localization GO:1902580 375 0.013
positive regulation of cytoplasmic transport GO:1903651 4 0.013
anatomical structure development GO:0048856 160 0.013
nucleoside phosphate biosynthetic process GO:1901293 80 0.013
protein modification by small protein conjugation GO:0032446 144 0.013
establishment of protein localization to organelle GO:0072594 278 0.013
protein modification by small protein conjugation or removal GO:0070647 172 0.013
regulation of phosphorus metabolic process GO:0051174 230 0.013
negative regulation of phosphorus metabolic process GO:0010563 49 0.013
regulation of phosphate metabolic process GO:0019220 230 0.012
ascospore formation GO:0030437 107 0.012
chromatin silencing at silent mating type cassette GO:0030466 53 0.012
mitotic chromosome condensation GO:0007076 11 0.012
negative regulation of protein catabolic process GO:0042177 27 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
cellular developmental process GO:0048869 191 0.012
dna topological change GO:0006265 10 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
lagging strand elongation GO:0006273 10 0.012
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.011
peptidyl amino acid modification GO:0018193 116 0.011
positive regulation of intracellular protein transport GO:0090316 3 0.011
chromatin remodeling GO:0006338 80 0.011
regulation of dna recombination GO:0000018 24 0.011
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.011
maintenance of sister chromatid cohesion GO:0034086 4 0.011
intracellular signal transduction GO:0035556 112 0.011
positive regulation of intracellular transport GO:0032388 4 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.011
negative regulation of protein modification process GO:0031400 37 0.011
negative regulation of cell cycle GO:0045786 91 0.010
negative regulation of dna dependent dna replication GO:2000104 8 0.010
apoptotic process GO:0006915 30 0.010
response to uv GO:0009411 4 0.010
protein maturation GO:0051604 76 0.010
intracellular protein transport GO:0006886 319 0.010
negative regulation of meiosis GO:0045835 23 0.010

SMC6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.012
cancer DOID:162 0 0.012