Saccharomyces cerevisiae

76 known processes

CHK1 (YBR274W)

Chk1p

CHK1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of biosynthetic process GO:0009891 336 0.271
Yeast
cell communication GO:0007154 345 0.254
Yeast
nuclear division GO:0000280 263 0.235
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.177
Yeast
nucleoside phosphate biosynthetic process GO:1901293 80 0.174
organelle fission GO:0048285 272 0.170
regulation of phosphate metabolic process GO:0019220 230 0.164
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.156
Yeast
dna repair GO:0006281 236 0.151
regulation of catalytic activity GO:0050790 307 0.145
cellular response to dna damage stimulus GO:0006974 287 0.141
organophosphate biosynthetic process GO:0090407 182 0.138
nucleotide biosynthetic process GO:0009165 79 0.137
actin filament based process GO:0030029 104 0.136
regulation of phosphorus metabolic process GO:0051174 230 0.135
telomere maintenance GO:0000723 74 0.133
positive regulation of cellular biosynthetic process GO:0031328 336 0.131
Yeast
single organism developmental process GO:0044767 258 0.130
mitotic cell cycle process GO:1903047 294 0.126
Yeast
negative regulation of cellular catabolic process GO:0031330 43 0.124
Yeast
phosphorylation GO:0016310 291 0.121
cellular developmental process GO:0048869 191 0.119
cell differentiation GO:0030154 161 0.118
carbohydrate derivative metabolic process GO:1901135 549 0.112
mitotic cell cycle GO:0000278 306 0.109
Yeast
response to abiotic stimulus GO:0009628 159 0.108
nucleoside phosphate metabolic process GO:0006753 458 0.104
response to chemical GO:0042221 390 0.104
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.104
Yeast
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.103
Yeast
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.100
Yeast
developmental process GO:0032502 261 0.098
dna recombination GO:0006310 172 0.097
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.094
cell cycle phase transition GO:0044770 144 0.091
Yeast
single organism signaling GO:0044700 208 0.091
Yeast
signal transduction GO:0007165 208 0.084
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.083
Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.079
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.073
organonitrogen compound biosynthetic process GO:1901566 314 0.072
Yeast
macromolecule catabolic process GO:0009057 383 0.071
double strand break repair GO:0006302 105 0.067
intracellular signal transduction GO:0035556 112 0.066
Yeast
gene silencing GO:0016458 151 0.066
chemical homeostasis GO:0048878 137 0.066
Yeast
positive regulation of phosphorus metabolic process GO:0010562 147 0.065
negative regulation of biosynthetic process GO:0009890 312 0.063
cellular response to chemical stimulus GO:0070887 315 0.061
Yeast
regulation of molecular function GO:0065009 320 0.060
Yeast
regulation of mitosis GO:0007088 65 0.059
cytoskeleton organization GO:0007010 230 0.059
organophosphate metabolic process GO:0019637 597 0.058
negative regulation of macromolecule metabolic process GO:0010605 375 0.057
filamentous growth GO:0030447 124 0.057
Yeast
negative regulation of cellular metabolic process GO:0031324 407 0.056
mitotic cell cycle phase transition GO:0044772 141 0.056
Yeast
growth GO:0040007 157 0.054
Yeast
regulation of signal transduction GO:0009966 114 0.053
exit from mitosis GO:0010458 37 0.053
regulation of signaling GO:0023051 119 0.051
single organism catabolic process GO:0044712 619 0.051
Yeast
positive regulation of rna metabolic process GO:0051254 294 0.050
Yeast
nucleobase containing compound catabolic process GO:0034655 479 0.049
positive regulation of phosphate metabolic process GO:0045937 147 0.049
ribonucleoside triphosphate metabolic process GO:0009199 356 0.048
homeostatic process GO:0042592 227 0.047
Yeast
regulation of catabolic process GO:0009894 199 0.047
Yeast
nitrogen compound transport GO:0071705 212 0.047
Yeast
chromatin organization GO:0006325 242 0.046
meiosis i GO:0007127 92 0.045
regulation of cell cycle process GO:0010564 150 0.045
meiotic cell cycle process GO:1903046 229 0.045
cellular response to osmotic stress GO:0071470 50 0.045
cellular macromolecule catabolic process GO:0044265 363 0.044
dna damage checkpoint GO:0000077 29 0.044
negative regulation of transcription dna templated GO:0045892 258 0.044
Yeast
dna conformation change GO:0071103 98 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.043
regulation of localization GO:0032879 127 0.043
Yeast
telomere organization GO:0032200 75 0.042
carbohydrate derivative biosynthetic process GO:1901137 181 0.041
chromatin silencing GO:0006342 147 0.041
positive regulation of rna biosynthetic process GO:1902680 286 0.041
Yeast
ribose phosphate metabolic process GO:0019693 384 0.040
cell cycle g2 m phase transition GO:0044839 39 0.040
positive regulation of transcription dna templated GO:0045893 286 0.040
Yeast
aging GO:0007568 71 0.039
protein phosphorylation GO:0006468 197 0.039
cellular response to organic substance GO:0071310 159 0.039
Yeast
protein processing GO:0016485 64 0.038
regulation of gene expression epigenetic GO:0040029 147 0.037
organic acid metabolic process GO:0006082 352 0.037
purine ribonucleotide metabolic process GO:0009150 372 0.037
mitotic nuclear division GO:0007067 131 0.036
proteolysis GO:0006508 268 0.035
Yeast
regulation of biological quality GO:0065008 391 0.034
Yeast
positive regulation of molecular function GO:0044093 185 0.034
endocytosis GO:0006897 90 0.034
Yeast
regulation of protein processing GO:0070613 34 0.034
negative regulation of protein maturation GO:1903318 33 0.033
response to external stimulus GO:0009605 158 0.033
Yeast
aromatic compound catabolic process GO:0019439 491 0.032
negative regulation of catabolic process GO:0009895 43 0.032
Yeast
transcription from rna polymerase i promoter GO:0006360 63 0.032
regulation of cellular component organization GO:0051128 334 0.032
Yeast
rrna transcription GO:0009303 31 0.032
regulation of transport GO:0051049 85 0.031
Yeast
anatomical structure homeostasis GO:0060249 74 0.031
negative regulation of protein processing GO:0010955 33 0.031
purine ribonucleoside metabolic process GO:0046128 380 0.031
regulation of cellular protein metabolic process GO:0032268 232 0.031
dna integrity checkpoint GO:0031570 41 0.030
chromatin modification GO:0016568 200 0.030
nuclear export GO:0051168 124 0.030
actin cytoskeleton organization GO:0030036 100 0.028
sporulation GO:0043934 132 0.028
single organism carbohydrate metabolic process GO:0044723 237 0.028
cell aging GO:0007569 70 0.028
positive regulation of cell cycle process GO:0090068 31 0.028
regulation of protein maturation GO:1903317 34 0.028
regulation of organelle organization GO:0033043 243 0.027
cellular response to external stimulus GO:0071496 150 0.027
Yeast
nucleus organization GO:0006997 62 0.027
recombinational repair GO:0000725 64 0.027
nucleoside triphosphate metabolic process GO:0009141 364 0.026
meiotic cell cycle GO:0051321 272 0.026
protein autophosphorylation GO:0046777 15 0.026
regulation of dna replication GO:0006275 51 0.026
protein maturation GO:0051604 76 0.026
purine nucleotide metabolic process GO:0006163 376 0.026
cellular carbohydrate metabolic process GO:0044262 135 0.025
negative regulation of cellular component organization GO:0051129 109 0.025
Yeast
reproductive process GO:0022414 248 0.025
Yeast
regulation of hydrolase activity GO:0051336 133 0.024
positive regulation of gene expression GO:0010628 321 0.024
Yeast
regulation of response to stimulus GO:0048583 157 0.023
Yeast
regulation of cell communication GO:0010646 124 0.023
Yeast
cellular response to oxidative stress GO:0034599 94 0.023
hexose metabolic process GO:0019318 78 0.023
nucleoside metabolic process GO:0009116 394 0.023
response to osmotic stress GO:0006970 83 0.022
ribonucleoside catabolic process GO:0042454 332 0.022
anatomical structure development GO:0048856 160 0.022
mating type determination GO:0007531 32 0.022
negative regulation of phosphate metabolic process GO:0045936 49 0.022
regulation of cell cycle GO:0051726 195 0.022
purine nucleoside triphosphate metabolic process GO:0009144 356 0.022
positive regulation of nucleic acid templated transcription GO:1903508 286 0.022
Yeast
single organism reproductive process GO:0044702 159 0.022
dna packaging GO:0006323 55 0.021
nucleobase containing small molecule metabolic process GO:0055086 491 0.021
anatomical structure morphogenesis GO:0009653 160 0.021
regulation of cell division GO:0051302 113 0.021
rna transport GO:0050658 92 0.021
negative regulation of phosphorus metabolic process GO:0010563 49 0.021
positive regulation of catalytic activity GO:0043085 178 0.020
regulation of cellular catabolic process GO:0031329 195 0.020
Yeast
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.020
protein complex assembly GO:0006461 302 0.020
negative regulation of organelle organization GO:0010639 103 0.020
filamentous growth of a population of unicellular organisms GO:0044182 109 0.020
Yeast
regulation of response to stress GO:0080134 57 0.020
Yeast
negative regulation of cellular biosynthetic process GO:0031327 312 0.020
nucleotide metabolic process GO:0009117 453 0.020
mitotic cell cycle checkpoint GO:0007093 56 0.019
regulation of purine nucleotide metabolic process GO:1900542 109 0.019
positive regulation of kinase activity GO:0033674 24 0.019
posttranscriptional regulation of gene expression GO:0010608 115 0.019
response to uv GO:0009411 4 0.019
cell cycle checkpoint GO:0000075 82 0.019
regulation of phosphorylation GO:0042325 86 0.019
negative regulation of gene expression GO:0010629 312 0.018
Yeast
protein complex biogenesis GO:0070271 314 0.018
glycosyl compound metabolic process GO:1901657 398 0.018
ribose phosphate biosynthetic process GO:0046390 50 0.018
positive regulation of intracellular transport GO:0032388 4 0.018
heterocycle catabolic process GO:0046700 494 0.018
mitotic spindle checkpoint GO:0071174 34 0.018
rrna metabolic process GO:0016072 244 0.018
regulation of cellular response to stress GO:0080135 50 0.018
Yeast
organic cyclic compound catabolic process GO:1901361 499 0.018
purine containing compound biosynthetic process GO:0072522 53 0.018
dna biosynthetic process GO:0071897 33 0.018
positive regulation of macromolecule metabolic process GO:0010604 394 0.017
Yeast
oxoacid metabolic process GO:0043436 351 0.017
negative regulation of mitosis GO:0045839 39 0.017
nucleoside triphosphate biosynthetic process GO:0009142 22 0.017
negative regulation of nucleic acid templated transcription GO:1903507 260 0.017
Yeast
cellular polysaccharide metabolic process GO:0044264 55 0.017
negative regulation of chromosome organization GO:2001251 39 0.017
carboxylic acid biosynthetic process GO:0046394 152 0.017
signaling GO:0023052 208 0.017
Yeast
transcription of nuclear large rrna transcript from rna polymerase i promoter GO:0042790 19 0.017
microtubule based process GO:0007017 117 0.016
oxidation reduction process GO:0055114 353 0.016
response to organic cyclic compound GO:0014070 1 0.016
organophosphate catabolic process GO:0046434 338 0.016
positive regulation of apoptotic process GO:0043065 3 0.016
lipid biosynthetic process GO:0008610 170 0.016
Yeast
mating type switching GO:0007533 28 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.016
Yeast
negative regulation of cell cycle process GO:0010948 86 0.016
negative regulation of catalytic activity GO:0043086 60 0.016
purine nucleoside metabolic process GO:0042278 380 0.016
regulation of kinase activity GO:0043549 71 0.016
organonitrogen compound catabolic process GO:1901565 404 0.016
positive regulation of hydrolase activity GO:0051345 112 0.015
macromolecule methylation GO:0043414 85 0.015
positive regulation of intracellular protein transport GO:0090316 3 0.015
regulation of mitotic cell cycle GO:0007346 107 0.015
regulation of cell cycle phase transition GO:1901987 70 0.015
positive regulation of cell death GO:0010942 3 0.015
cellular ketone metabolic process GO:0042180 63 0.015
chromatin silencing at rdna GO:0000183 32 0.015
vesicle mediated transport GO:0016192 335 0.015
Yeast
dna dependent dna replication GO:0006261 115 0.015
dephosphorylation GO:0016311 127 0.015
Yeast
reproduction of a single celled organism GO:0032505 191 0.015
ribosomal large subunit biogenesis GO:0042273 98 0.015
negative regulation of proteolysis GO:0045861 33 0.014
cellular response to abiotic stimulus GO:0071214 62 0.014
nucleotide catabolic process GO:0009166 330 0.014
positive regulation of protein metabolic process GO:0051247 93 0.014
negative regulation of molecular function GO:0044092 68 0.014
negative regulation of rna metabolic process GO:0051253 262 0.014
Yeast
dna replication GO:0006260 147 0.014
response to organic substance GO:0010033 182 0.014
Yeast
purine ribonucleotide biosynthetic process GO:0009152 39 0.014
protein dephosphorylation GO:0006470 40 0.014
Yeast
purine nucleotide catabolic process GO:0006195 328 0.014
purine containing compound catabolic process GO:0072523 332 0.014
regulation of nucleoside metabolic process GO:0009118 106 0.014
carbohydrate derivative catabolic process GO:1901136 339 0.014
cell development GO:0048468 107 0.014
cell fate commitment GO:0045165 32 0.013
regulation of transferase activity GO:0051338 83 0.013
organelle assembly GO:0070925 118 0.013
glucose metabolic process GO:0006006 65 0.013
cellular response to starvation GO:0009267 90 0.013
Yeast
fungal type cell wall organization GO:0031505 145 0.013
covalent chromatin modification GO:0016569 119 0.013
non recombinational repair GO:0000726 33 0.013
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.013
nucleoside monophosphate metabolic process GO:0009123 267 0.013
negative regulation of cell cycle phase transition GO:1901988 59 0.013
regulation of dna metabolic process GO:0051052 100 0.013
regulation of intracellular signal transduction GO:1902531 78 0.013
cellular protein complex assembly GO:0043623 209 0.013
cell division GO:0051301 205 0.013
rna localization GO:0006403 112 0.013
positive regulation of catabolic process GO:0009896 135 0.013
negative regulation of cell cycle GO:0045786 91 0.013
purine ribonucleoside catabolic process GO:0046130 330 0.013
cell cycle g1 s phase transition GO:0044843 64 0.013
Yeast
regulation of protein localization GO:0032880 62 0.013
cellular amino acid metabolic process GO:0006520 225 0.013
g2 m transition of mitotic cell cycle GO:0000086 38 0.013
negative regulation of gene expression epigenetic GO:0045814 147 0.013
regulation of nuclear division GO:0051783 103 0.012
invasive growth in response to glucose limitation GO:0001403 61 0.012
g1 s transition of mitotic cell cycle GO:0000082 64 0.012
Yeast
positive regulation of cytoplasmic transport GO:1903651 4 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.012
invasive filamentous growth GO:0036267 65 0.012
death GO:0016265 30 0.012
microtubule cytoskeleton organization GO:0000226 109 0.012
modification dependent macromolecule catabolic process GO:0043632 203 0.012
gtp catabolic process GO:0006184 107 0.012
methylation GO:0032259 101 0.012
peptidyl amino acid modification GO:0018193 116 0.011
glycosyl compound catabolic process GO:1901658 335 0.011
autophagy GO:0006914 106 0.011
Yeast
cellular response to oxygen containing compound GO:1901701 43 0.011
glycoprotein biosynthetic process GO:0009101 61 0.011
double strand break repair via homologous recombination GO:0000724 54 0.011
nucleoside phosphate catabolic process GO:1901292 331 0.011
purine containing compound metabolic process GO:0072521 400 0.011
regulation of protein catabolic process GO:0042176 40 0.011
generation of precursor metabolites and energy GO:0006091 147 0.011
ribonucleoside metabolic process GO:0009119 389 0.011
response to drug GO:0042493 41 0.011
cellular response to heat GO:0034605 53 0.011
nucleobase containing compound transport GO:0015931 124 0.011
mitochondrion organization GO:0007005 261 0.011
regulation of intracellular transport GO:0032386 26 0.011
replicative cell aging GO:0001302 46 0.011
anatomical structure formation involved in morphogenesis GO:0048646 136 0.011
regulation of mitotic cell cycle phase transition GO:1901990 68 0.011
negative regulation of cell division GO:0051782 66 0.011
regulation of protein modification process GO:0031399 110 0.011
rrna processing GO:0006364 227 0.011
response to nutrient levels GO:0031667 150 0.011
Yeast
cellular response to topologically incorrect protein GO:0035967 32 0.011
regulation of protein phosphorylation GO:0001932 75 0.011
intracellular protein transport GO:0006886 319 0.011
spindle assembly checkpoint GO:0071173 23 0.011
ribonucleoside triphosphate catabolic process GO:0009203 327 0.011
purine nucleoside catabolic process GO:0006152 330 0.010
positive regulation of phosphorylation GO:0042327 33 0.010
regulation of protein metabolic process GO:0051246 237 0.010
cellular homeostasis GO:0019725 138 0.010
Yeast
negative regulation of mitotic cell cycle GO:0045930 63 0.010
chromosome condensation GO:0030261 19 0.010
er nucleus signaling pathway GO:0006984 23 0.010
response to heat GO:0009408 69 0.010
cell death GO:0008219 30 0.010
negative regulation of phosphorylation GO:0042326 28 0.010
nucleocytoplasmic transport GO:0006913 163 0.010

CHK1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020