Saccharomyces cerevisiae

20 known processes

MDH1 (YKL085W)

Mdh1p

MDH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
energy derivation by oxidation of organic compounds GO:0015980 125 0.964
coenzyme metabolic process GO:0006732 104 0.768
oxidation reduction process GO:0055114 353 0.673
cofactor metabolic process GO:0051186 126 0.650
nucleotide metabolic process GO:0009117 453 0.615
generation of precursor metabolites and energy GO:0006091 147 0.600
organophosphate metabolic process GO:0019637 597 0.556
cellular protein complex assembly GO:0043623 209 0.444
mitochondrial electron transport ubiquinol to cytochrome c GO:0006122 11 0.431
aerobic respiration GO:0009060 55 0.421
nucleoside phosphate metabolic process GO:0006753 458 0.357
nicotinamide nucleotide metabolic process GO:0046496 44 0.315
oxidoreduction coenzyme metabolic process GO:0006733 58 0.272
cellular respiration GO:0045333 82 0.271
atp synthesis coupled electron transport GO:0042773 25 0.256
tricarboxylic acid metabolic process GO:0072350 3 0.233
cytochrome complex assembly GO:0017004 29 0.229
nadh metabolic process GO:0006734 12 0.204
nucleobase containing small molecule metabolic process GO:0055086 491 0.191
monocarboxylic acid metabolic process GO:0032787 122 0.185
pyridine nucleotide metabolic process GO:0019362 45 0.183
purine ribonucleoside triphosphate biosynthetic process GO:0009206 17 0.181
protein complex assembly GO:0006461 302 0.178
mitochondrial atp synthesis coupled electron transport GO:0042775 25 0.177
translation GO:0006412 230 0.159
nucleoside triphosphate metabolic process GO:0009141 364 0.150
ribonucleoside metabolic process GO:0009119 389 0.147
dicarboxylic acid metabolic process GO:0043648 20 0.145
glycosyl compound metabolic process GO:1901657 398 0.144
oxoacid metabolic process GO:0043436 351 0.143
nucleoside monophosphate metabolic process GO:0009123 267 0.142
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.136
tricarboxylic acid cycle GO:0006099 6 0.133
purine ribonucleotide metabolic process GO:0009150 372 0.129
carbohydrate derivative metabolic process GO:1901135 549 0.128
organic acid metabolic process GO:0006082 352 0.124
acyl coa metabolic process GO:0006637 13 0.115
ribonucleotide metabolic process GO:0009259 377 0.114
detection of glucose GO:0051594 3 0.111
response to organic cyclic compound GO:0014070 1 0.111
regulation of cellular component organization GO:0051128 334 0.106
cellular nitrogen compound catabolic process GO:0044270 494 0.105
electron transport chain GO:0022900 25 0.105
transmembrane transport GO:0055085 349 0.100
developmental process GO:0032502 261 0.099
cell aging GO:0007569 70 0.089
purine ribonucleoside metabolic process GO:0046128 380 0.082
protein complex biogenesis GO:0070271 314 0.079
regulation of phosphate metabolic process GO:0019220 230 0.075
cellular amine metabolic process GO:0044106 51 0.075
mitochondrial translation GO:0032543 52 0.074
hydrogen ion transmembrane transport GO:1902600 49 0.073
ribose phosphate metabolic process GO:0019693 384 0.072
nucleotide biosynthetic process GO:0009165 79 0.072
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.069
single organism catabolic process GO:0044712 619 0.067
regulation of meiotic cell cycle GO:0051445 43 0.066
aromatic compound catabolic process GO:0019439 491 0.066
nucleoside triphosphate catabolic process GO:0009143 329 0.066
respiratory electron transport chain GO:0022904 25 0.066
thioester metabolic process GO:0035383 13 0.065
negative regulation of protein metabolic process GO:0051248 85 0.065
cellular response to chemical stimulus GO:0070887 315 0.064
regulation of cellular amine metabolic process GO:0033238 21 0.064
single organism membrane organization GO:0044802 275 0.063
heterocycle catabolic process GO:0046700 494 0.062
amine metabolic process GO:0009308 51 0.062
purine nucleoside triphosphate metabolic process GO:0009144 356 0.061
protein transmembrane transport GO:0071806 82 0.061
purine nucleoside monophosphate metabolic process GO:0009126 262 0.060
negative regulation of cellular protein metabolic process GO:0032269 85 0.059
pyridine containing compound metabolic process GO:0072524 53 0.058
response to chemical GO:0042221 390 0.058
organophosphate biosynthetic process GO:0090407 182 0.057
regulation of phosphorus metabolic process GO:0051174 230 0.057
regulation of translation GO:0006417 89 0.055
branched chain amino acid metabolic process GO:0009081 16 0.054
nad metabolic process GO:0019674 25 0.054
response to organic substance GO:0010033 182 0.053
ribonucleotide catabolic process GO:0009261 327 0.053
gtp metabolic process GO:0046039 107 0.053
purine nucleotide metabolic process GO:0006163 376 0.052
mitochondrial genome maintenance GO:0000002 40 0.052
protein transport GO:0015031 345 0.051
detection of hexose stimulus GO:0009732 3 0.049
negative regulation of organelle organization GO:0010639 103 0.049
single organism developmental process GO:0044767 258 0.048
carbohydrate metabolic process GO:0005975 252 0.047
protein dna complex subunit organization GO:0071824 153 0.047
purine nucleotide catabolic process GO:0006195 328 0.045
nucleotide catabolic process GO:0009166 330 0.045
ribonucleoside triphosphate catabolic process GO:0009203 327 0.045
regulation of cellular protein metabolic process GO:0032268 232 0.044
ribonucleoside triphosphate metabolic process GO:0009199 356 0.043
glucose metabolic process GO:0006006 65 0.043
nucleobase containing compound catabolic process GO:0034655 479 0.042
energy coupled proton transport down electrochemical gradient GO:0015985 17 0.042
phosphorylation GO:0016310 291 0.042
cofactor biosynthetic process GO:0051188 80 0.042
purine ribonucleoside catabolic process GO:0046130 330 0.042
positive regulation of apoptotic process GO:0043065 3 0.041
small molecule biosynthetic process GO:0044283 258 0.040
establishment of protein localization GO:0045184 367 0.040
developmental process involved in reproduction GO:0003006 159 0.039
mitochondrion organization GO:0007005 261 0.039
organonitrogen compound biosynthetic process GO:1901566 314 0.039
nucleoside catabolic process GO:0009164 335 0.037
purine nucleoside metabolic process GO:0042278 380 0.037
purine ribonucleotide catabolic process GO:0009154 327 0.037
organonitrogen compound catabolic process GO:1901565 404 0.037
reproductive process GO:0022414 248 0.037
carboxylic acid metabolic process GO:0019752 338 0.037
cellular amino acid biosynthetic process GO:0008652 118 0.036
purine containing compound catabolic process GO:0072523 332 0.036
chromatin silencing at rdna GO:0000183 32 0.036
ribonucleoside monophosphate metabolic process GO:0009161 265 0.035
detection of monosaccharide stimulus GO:0034287 3 0.035
negative regulation of macromolecule metabolic process GO:0010605 375 0.035
cellular developmental process GO:0048869 191 0.034
atp metabolic process GO:0046034 251 0.034
cytoplasmic translation GO:0002181 65 0.034
inorganic ion transmembrane transport GO:0098660 109 0.034
nucleoside metabolic process GO:0009116 394 0.033
purine containing compound metabolic process GO:0072521 400 0.033
macromolecular complex disassembly GO:0032984 80 0.033
nucleoside phosphate biosynthetic process GO:1901293 80 0.033
regulation of molecular function GO:0065009 320 0.032
purine nucleoside catabolic process GO:0006152 330 0.032
organic cyclic compound catabolic process GO:1901361 499 0.032
aging GO:0007568 71 0.031
negative regulation of cellular component organization GO:0051129 109 0.031
negative regulation of cell cycle GO:0045786 91 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.031
purine nucleotide biosynthetic process GO:0006164 41 0.030
purine ribonucleoside monophosphate biosynthetic process GO:0009168 28 0.029
carbohydrate derivative catabolic process GO:1901136 339 0.028
organophosphate catabolic process GO:0046434 338 0.027
regulation of catalytic activity GO:0050790 307 0.027
sulfur compound metabolic process GO:0006790 95 0.027
negative regulation of cell cycle process GO:0010948 86 0.027
negative regulation of protein modification process GO:0031400 37 0.026
ribonucleoside catabolic process GO:0042454 332 0.026
cellular response to organic substance GO:0071310 159 0.026
regulation of generation of precursor metabolites and energy GO:0043467 23 0.025
regulation of protein metabolic process GO:0051246 237 0.025
cell differentiation GO:0030154 161 0.025
nuclear export GO:0051168 124 0.025
mitochondrial respiratory chain complex assembly GO:0033108 36 0.025
carbon catabolite activation of transcription GO:0045991 26 0.024
cellular ketone metabolic process GO:0042180 63 0.023
glycosyl compound catabolic process GO:1901658 335 0.023
regulation of signaling GO:0023051 119 0.023
regulation of dna replication GO:0006275 51 0.023
purine containing compound biosynthetic process GO:0072522 53 0.022
regulation of cell cycle process GO:0010564 150 0.022
response to extracellular stimulus GO:0009991 156 0.022
carboxylic acid biosynthetic process GO:0046394 152 0.021
positive regulation of cellular component organization GO:0051130 116 0.021
response to external stimulus GO:0009605 158 0.021
alcohol biosynthetic process GO:0046165 75 0.021
positive regulation of phosphorus metabolic process GO:0010562 147 0.020
positive regulation of rna metabolic process GO:0051254 294 0.020
single organism cellular localization GO:1902580 375 0.020
regulation of catabolic process GO:0009894 199 0.020
nucleoside triphosphate biosynthetic process GO:0009142 22 0.020
carbon catabolite regulation of transcription GO:0045990 39 0.020
tetrapyrrole biosynthetic process GO:0033014 14 0.020
mitochondrial respiratory chain complex iv biogenesis GO:0097034 26 0.020
phospholipid metabolic process GO:0006644 125 0.020
cellular amino acid metabolic process GO:0006520 225 0.019
intracellular protein transmembrane import GO:0044743 67 0.019
organelle localization GO:0051640 128 0.019
purine ribonucleotide biosynthetic process GO:0009152 39 0.018
inorganic cation transmembrane transport GO:0098662 98 0.018
covalent chromatin modification GO:0016569 119 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.018
regulation of protein modification process GO:0031399 110 0.017
regulation of transferase activity GO:0051338 83 0.017
protein maturation GO:0051604 76 0.017
mitochondrial respiratory chain complex iv assembly GO:0033617 18 0.017
negative regulation of biosynthetic process GO:0009890 312 0.017
posttranscriptional regulation of gene expression GO:0010608 115 0.017
glycerolipid metabolic process GO:0046486 108 0.017
tetrapyrrole metabolic process GO:0033013 15 0.017
regulation of meiosis GO:0040020 42 0.017
positive regulation of organelle organization GO:0010638 85 0.016
regulation of phosphorylation GO:0042325 86 0.016
regulation of nuclear division GO:0051783 103 0.016
cell morphogenesis GO:0000902 30 0.016
purine nucleoside monophosphate biosynthetic process GO:0009127 28 0.016
regulation of cellular catabolic process GO:0031329 195 0.016
establishment of protein localization to mitochondrion GO:0072655 63 0.016
chromatin organization GO:0006325 242 0.016
coenzyme biosynthetic process GO:0009108 66 0.016
positive regulation of protein metabolic process GO:0051247 93 0.015
organic hydroxy compound metabolic process GO:1901615 125 0.015
positive regulation of nucleotide metabolic process GO:0045981 101 0.015
regulation of organelle organization GO:0033043 243 0.015
negative regulation of phosphorus metabolic process GO:0010563 49 0.015
protein phosphorylation GO:0006468 197 0.015
nucleoside phosphate catabolic process GO:1901292 331 0.015
regulation of nucleotide metabolic process GO:0006140 110 0.015
regulation of cellular amino acid metabolic process GO:0006521 16 0.015
positive regulation of cellular amine metabolic process GO:0033240 10 0.014
mitotic cell cycle process GO:1903047 294 0.014
ribonucleoprotein complex subunit organization GO:0071826 152 0.014
mitochondrial respiratory chain complex iii biogenesis GO:0097033 11 0.014
positive regulation of cell death GO:0010942 3 0.014
monosaccharide metabolic process GO:0005996 83 0.014
guanosine containing compound catabolic process GO:1901069 109 0.014
protein localization to plasma membrane GO:0072659 18 0.014
carbohydrate biosynthetic process GO:0016051 82 0.014
regulation of protein phosphorylation GO:0001932 75 0.014
nucleoside monophosphate biosynthetic process GO:0009124 33 0.014
regulation of cell cycle GO:0051726 195 0.014
cellular response to nutrient levels GO:0031669 144 0.014
cellular cation homeostasis GO:0030003 100 0.014
regulation of purine nucleotide metabolic process GO:1900542 109 0.014
regulation of nucleoside metabolic process GO:0009118 106 0.014
single organism reproductive process GO:0044702 159 0.014
anatomical structure homeostasis GO:0060249 74 0.013
cell cycle checkpoint GO:0000075 82 0.013
regulation of phosphatidylcholine biosynthetic process GO:2001245 7 0.013
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.013
ribonucleotide biosynthetic process GO:0009260 44 0.013
intracellular protein transport GO:0006886 319 0.013
rna transport GO:0050658 92 0.013
positive regulation of biosynthetic process GO:0009891 336 0.013
detection of chemical stimulus GO:0009593 3 0.013
cellular biogenic amine metabolic process GO:0006576 37 0.013
ribose phosphate biosynthetic process GO:0046390 50 0.013
positive regulation of molecular function GO:0044093 185 0.013
signal transduction GO:0007165 208 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.013
single organism carbohydrate metabolic process GO:0044723 237 0.013
protein localization to membrane GO:0072657 102 0.013
respiratory chain complex iv assembly GO:0008535 18 0.013
meiotic nuclear division GO:0007126 163 0.013
negative regulation of cellular metabolic process GO:0031324 407 0.013
positive regulation of programmed cell death GO:0043068 3 0.013
positive regulation of intracellular protein transport GO:0090316 3 0.012
atp catabolic process GO:0006200 224 0.012
establishment of rna localization GO:0051236 92 0.012
positive regulation of secretion GO:0051047 2 0.012
nucleoside biosynthetic process GO:0009163 38 0.012
hexose metabolic process GO:0019318 78 0.012
negative regulation of transferase activity GO:0051348 31 0.012
divalent inorganic cation homeostasis GO:0072507 21 0.012
monovalent inorganic cation transport GO:0015672 78 0.012
pigment biosynthetic process GO:0046148 22 0.012
positive regulation of cellular biosynthetic process GO:0031328 336 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.012
positive regulation of gene expression GO:0010628 321 0.012
purine nucleoside triphosphate biosynthetic process GO:0009145 17 0.012
intracellular protein transmembrane transport GO:0065002 80 0.012
autophagy GO:0006914 106 0.012
protein localization to mitochondrion GO:0070585 63 0.012
leucine metabolic process GO:0006551 8 0.012
regulation of nucleotide catabolic process GO:0030811 106 0.012
response to oxidative stress GO:0006979 99 0.012
regulation of hydrolase activity GO:0051336 133 0.011
multi organism process GO:0051704 233 0.011
histone modification GO:0016570 119 0.011
rna localization GO:0006403 112 0.011
protein folding GO:0006457 94 0.011
regulation of mitochondrion organization GO:0010821 20 0.011
regulation of cell cycle phase transition GO:1901987 70 0.011
response to starvation GO:0042594 96 0.011
cellular homeostasis GO:0019725 138 0.011
regulation of cell division GO:0051302 113 0.011
replicative cell aging GO:0001302 46 0.011
homeostatic process GO:0042592 227 0.011
positive regulation of cellular protein metabolic process GO:0032270 89 0.011
alpha amino acid metabolic process GO:1901605 124 0.011
regulation of mitochondrial translation GO:0070129 15 0.011
phospholipid biosynthetic process GO:0008654 89 0.010
negative regulation of nuclear division GO:0051784 62 0.010
regulation of cellular respiration GO:0043457 7 0.010
cell communication GO:0007154 345 0.010
ribonucleoside monophosphate biosynthetic process GO:0009156 31 0.010
response to endogenous stimulus GO:0009719 26 0.010
anatomical structure development GO:0048856 160 0.010
positive regulation of cellular catabolic process GO:0031331 128 0.010
organic acid biosynthetic process GO:0016053 152 0.010

MDH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.026
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
disease of anatomical entity DOID:7 0 0.014
inherited metabolic disorder DOID:655 0 0.010
disease of metabolism DOID:0014667 0 0.010