Saccharomyces cerevisiae

14 known processes

PDI1 (YCL043C)

Pdi1p

(Aliases: TRG1,MFP1)

PDI1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein folding GO:0006457 94 0.565
protein transport GO:0015031 345 0.307
establishment of protein localization GO:0045184 367 0.299
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.270
carbohydrate metabolic process GO:0005975 252 0.260
protein catabolic process GO:0030163 221 0.203
positive regulation of macromolecule metabolic process GO:0010604 394 0.202
intracellular protein transport GO:0006886 319 0.193
glucose metabolic process GO:0006006 65 0.185
anatomical structure development GO:0048856 160 0.175
Worm
single organism developmental process GO:0044767 258 0.160
Worm
establishment of protein localization to organelle GO:0072594 278 0.139
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.127
developmental process GO:0032502 261 0.127
Worm
cellular macromolecule catabolic process GO:0044265 363 0.122
positive regulation of rna metabolic process GO:0051254 294 0.116
meiotic cell cycle GO:0051321 272 0.112
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.111
macromolecule catabolic process GO:0009057 383 0.108
negative regulation of cellular metabolic process GO:0031324 407 0.099
cellular protein catabolic process GO:0044257 213 0.099
hexose metabolic process GO:0019318 78 0.098
growth GO:0040007 157 0.097
proteolysis GO:0006508 268 0.096
single organism carbohydrate metabolic process GO:0044723 237 0.094
single organism signaling GO:0044700 208 0.094
Worm
anatomical structure morphogenesis GO:0009653 160 0.087
Worm
cellular developmental process GO:0048869 191 0.087
positive regulation of biosynthetic process GO:0009891 336 0.084
negative regulation of rna metabolic process GO:0051253 262 0.084
cell communication GO:0007154 345 0.083
Worm
response to starvation GO:0042594 96 0.082
protein import GO:0017038 122 0.080
signal transduction GO:0007165 208 0.077
Worm
cell differentiation GO:0030154 161 0.077
response to chemical GO:0042221 390 0.075
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.075
cellular response to organic substance GO:0071310 159 0.075
Worm
cellular response to chemical stimulus GO:0070887 315 0.074
Worm
negative regulation of nucleic acid templated transcription GO:1903507 260 0.073
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.071
single organism cellular localization GO:1902580 375 0.069
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.068
filamentous growth GO:0030447 124 0.066
filamentous growth of a population of unicellular organisms GO:0044182 109 0.066
modification dependent protein catabolic process GO:0019941 181 0.065
nuclear division GO:0000280 263 0.063
negative regulation of gene expression GO:0010629 312 0.061
negative regulation of rna biosynthetic process GO:1902679 260 0.061
mitochondrion organization GO:0007005 261 0.060
protein targeting GO:0006605 272 0.060
pyridine nucleotide metabolic process GO:0019362 45 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.055
positive regulation of cellular biosynthetic process GO:0031328 336 0.055
cellular nitrogen compound catabolic process GO:0044270 494 0.054
negative regulation of macromolecule metabolic process GO:0010605 375 0.053
single organism catabolic process GO:0044712 619 0.053
regulation of cellular protein metabolic process GO:0032268 232 0.053
cellular response to dna damage stimulus GO:0006974 287 0.051
regulation of biological quality GO:0065008 391 0.050
cellular response to external stimulus GO:0071496 150 0.049
sexual reproduction GO:0019953 216 0.048
positive regulation of gene expression GO:0010628 321 0.047
negative regulation of cellular biosynthetic process GO:0031327 312 0.047
cofactor metabolic process GO:0051186 126 0.047
reproductive process GO:0022414 248 0.047
regulation of phosphorus metabolic process GO:0051174 230 0.047
negative regulation of transcription dna templated GO:0045892 258 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.045
hexose biosynthetic process GO:0019319 30 0.044
regulation of transport GO:0051049 85 0.044
protein localization to organelle GO:0033365 337 0.041
cellular response to extracellular stimulus GO:0031668 150 0.040
positive regulation of rna biosynthetic process GO:1902680 286 0.040
cellular response to starvation GO:0009267 90 0.038
multi organism process GO:0051704 233 0.038
positive regulation of nucleic acid templated transcription GO:1903508 286 0.038
sporulation GO:0043934 132 0.037
cellular chemical homeostasis GO:0055082 123 0.037
gluconeogenesis GO:0006094 30 0.037
reproduction of a single celled organism GO:0032505 191 0.037
response to extracellular stimulus GO:0009991 156 0.036
ubiquitin dependent protein catabolic process GO:0006511 181 0.036
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.035
glucose catabolic process GO:0006007 17 0.035
dna replication GO:0006260 147 0.035
response to unfolded protein GO:0006986 29 0.035
Worm
protein phosphorylation GO:0006468 197 0.034
proteasomal protein catabolic process GO:0010498 141 0.034
phosphorylation GO:0016310 291 0.034
heterocycle catabolic process GO:0046700 494 0.034
organonitrogen compound catabolic process GO:1901565 404 0.034
dna repair GO:0006281 236 0.033
nadp metabolic process GO:0006739 16 0.033
protein modification by small protein conjugation GO:0032446 144 0.033
porphyrin containing compound metabolic process GO:0006778 15 0.033
nucleotide metabolic process GO:0009117 453 0.032
meiotic nuclear division GO:0007126 163 0.032
regulation of phosphorylation GO:0042325 86 0.032
ascospore formation GO:0030437 107 0.032
nadph regeneration GO:0006740 13 0.031
meiotic cell cycle process GO:1903046 229 0.031
organophosphate metabolic process GO:0019637 597 0.031
coenzyme metabolic process GO:0006732 104 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.030
carbohydrate catabolic process GO:0016052 77 0.030
regulation of localization GO:0032879 127 0.029
protein transmembrane transport GO:0071806 82 0.029
nucleoside phosphate metabolic process GO:0006753 458 0.029
response to topologically incorrect protein GO:0035966 38 0.029
Worm
sporulation resulting in formation of a cellular spore GO:0030435 129 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.028
dna integrity checkpoint GO:0031570 41 0.028
regulation of response to stimulus GO:0048583 157 0.028
signaling GO:0023052 208 0.028
Worm
response to external stimulus GO:0009605 158 0.028
positive regulation of transcription dna templated GO:0045893 286 0.028
rrna metabolic process GO:0016072 244 0.028
regulation of protein modification process GO:0031399 110 0.028
response to nutrient levels GO:0031667 150 0.027
single organism reproductive process GO:0044702 159 0.027
monosaccharide biosynthetic process GO:0046364 31 0.027
pentose phosphate shunt GO:0006098 10 0.027
aspartate family amino acid biosynthetic process GO:0009067 29 0.026
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.026
monosaccharide catabolic process GO:0046365 28 0.026
developmental process involved in reproduction GO:0003006 159 0.026
anatomical structure formation involved in morphogenesis GO:0048646 136 0.026
translation GO:0006412 230 0.026
protein modification by small protein conjugation or removal GO:0070647 172 0.026
oxidation reduction process GO:0055114 353 0.026
aromatic compound catabolic process GO:0019439 491 0.025
oxidoreduction coenzyme metabolic process GO:0006733 58 0.025
cell cycle checkpoint GO:0000075 82 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.025
sulfur compound biosynthetic process GO:0044272 53 0.025
regulation of protein metabolic process GO:0051246 237 0.025
protein complex assembly GO:0006461 302 0.024
positive regulation of programmed cell death GO:0043068 3 0.023
pigment biosynthetic process GO:0046148 22 0.023
nucleobase containing compound catabolic process GO:0034655 479 0.023
reproductive process in single celled organism GO:0022413 145 0.023
cellular homeostasis GO:0019725 138 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.023
membrane organization GO:0061024 276 0.023
heme metabolic process GO:0042168 15 0.023
modification dependent macromolecule catabolic process GO:0043632 203 0.023
posttranscriptional regulation of gene expression GO:0010608 115 0.022
regulation of catabolic process GO:0009894 199 0.022
regulation of molecular function GO:0065009 320 0.022
mitotic cell cycle process GO:1903047 294 0.022
cellular component morphogenesis GO:0032989 97 0.022
monosaccharide metabolic process GO:0005996 83 0.022
protein ubiquitination GO:0016567 118 0.022
intracellular protein transmembrane import GO:0044743 67 0.022
heme biosynthetic process GO:0006783 14 0.022
conjugation GO:0000746 107 0.021
sexual sporulation GO:0034293 113 0.021
rrna processing GO:0006364 227 0.021
homeostatic process GO:0042592 227 0.021
response to abiotic stimulus GO:0009628 159 0.021
carboxylic acid metabolic process GO:0019752 338 0.021
Worm
organic cyclic compound catabolic process GO:1901361 499 0.021
cell development GO:0048468 107 0.021
tetrapyrrole biosynthetic process GO:0033014 14 0.021
protein targeting to membrane GO:0006612 52 0.021
cell wall organization or biogenesis GO:0071554 190 0.020
ribonucleotide catabolic process GO:0009261 327 0.020
peptidyl amino acid modification GO:0018193 116 0.020
Worm
positive regulation of cellular protein metabolic process GO:0032270 89 0.019
positive regulation of protein metabolic process GO:0051247 93 0.019
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.019
single organism carbohydrate catabolic process GO:0044724 73 0.019
positive regulation of phosphorylation GO:0042327 33 0.019
generation of precursor metabolites and energy GO:0006091 147 0.019
positive regulation of protein modification process GO:0031401 49 0.019
aspartate family amino acid metabolic process GO:0009066 40 0.019
er to golgi vesicle mediated transport GO:0006888 86 0.018
positive regulation of phosphorus metabolic process GO:0010562 147 0.018
transmembrane transport GO:0055085 349 0.018
protein localization to nucleus GO:0034504 74 0.018
regulation of phosphate metabolic process GO:0019220 230 0.018
regulation of protein localization GO:0032880 62 0.018
response to endoplasmic reticulum stress GO:0034976 23 0.017
Worm
mitotic cell cycle GO:0000278 306 0.017
dna dependent dna replication GO:0006261 115 0.017
cellular ion homeostasis GO:0006873 112 0.017
cellular protein complex assembly GO:0043623 209 0.017
multi organism cellular process GO:0044764 120 0.017
regulation of cellular catabolic process GO:0031329 195 0.017
multi organism reproductive process GO:0044703 216 0.017
negative regulation of biosynthetic process GO:0009890 312 0.017
regulation of cellular component biogenesis GO:0044087 112 0.016
regulation of nuclear division GO:0051783 103 0.016
vesicle mediated transport GO:0016192 335 0.016
mapk cascade GO:0000165 30 0.016
small molecule catabolic process GO:0044282 88 0.016
ribonucleoside catabolic process GO:0042454 332 0.016
protein folding in endoplasmic reticulum GO:0034975 13 0.016
gene silencing GO:0016458 151 0.016
pseudohyphal growth GO:0007124 75 0.016
protein complex biogenesis GO:0070271 314 0.016
regulation of cellular component organization GO:0051128 334 0.015
cell growth GO:0016049 89 0.015
cell division GO:0051301 205 0.015
nucleoside triphosphate metabolic process GO:0009141 364 0.015
nucleoside triphosphate catabolic process GO:0009143 329 0.015
cell wall organization GO:0071555 146 0.015
organonitrogen compound biosynthetic process GO:1901566 314 0.015
conjugation with cellular fusion GO:0000747 106 0.015
reactive oxygen species metabolic process GO:0072593 10 0.015
nucleocytoplasmic transport GO:0006913 163 0.015
nucleobase containing small molecule metabolic process GO:0055086 491 0.014
regulation of signal transduction GO:0009966 114 0.014
pyruvate metabolic process GO:0006090 37 0.014
regulation of response to stress GO:0080134 57 0.014
protein maturation GO:0051604 76 0.014
regulation of catalytic activity GO:0050790 307 0.014
dna replication initiation GO:0006270 48 0.014
carbohydrate derivative metabolic process GO:1901135 549 0.014
glycosyl compound catabolic process GO:1901658 335 0.014
apoptotic process GO:0006915 30 0.013
nucleic acid transport GO:0050657 94 0.013
positive regulation of apoptotic process GO:0043065 3 0.013
response to organic cyclic compound GO:0014070 1 0.013
nicotinamide nucleotide metabolic process GO:0046496 44 0.013
dna damage checkpoint GO:0000077 29 0.013
purine nucleotide catabolic process GO:0006195 328 0.013
cell morphogenesis GO:0000902 30 0.013
positive regulation of cell death GO:0010942 3 0.013
regulation of translation GO:0006417 89 0.013
rna catabolic process GO:0006401 118 0.013
maintenance of protein location in cell GO:0032507 50 0.013
nuclear transport GO:0051169 165 0.013
aging GO:0007568 71 0.013
sulfur compound metabolic process GO:0006790 95 0.013
positive regulation of intracellular transport GO:0032388 4 0.013
cellular response to topologically incorrect protein GO:0035967 32 0.012
Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.012
cell aging GO:0007569 70 0.012
carbohydrate derivative catabolic process GO:1901136 339 0.012
fungal type cell wall organization GO:0031505 145 0.012
regulation of dna metabolic process GO:0051052 100 0.012
regulation of protein ubiquitination GO:0031396 20 0.012
pigment metabolic process GO:0042440 23 0.012
nucleoside monophosphate catabolic process GO:0009125 224 0.012
oxoacid metabolic process GO:0043436 351 0.012
Worm
negative regulation of cellular component organization GO:0051129 109 0.012
response to organic substance GO:0010033 182 0.012
Worm
negative regulation of transferase activity GO:0051348 31 0.012
single organism nuclear import GO:1902593 56 0.012
carbohydrate biosynthetic process GO:0016051 82 0.012
fungal type cell wall biogenesis GO:0009272 80 0.011
regulation of cell cycle GO:0051726 195 0.011
maintenance of location GO:0051235 66 0.011
er nucleus signaling pathway GO:0006984 23 0.011
Worm
purine nucleoside monophosphate catabolic process GO:0009128 224 0.011
establishment of protein localization to membrane GO:0090150 99 0.011
tetrapyrrole metabolic process GO:0033013 15 0.011
protein localization to membrane GO:0072657 102 0.011
positive regulation of intracellular protein transport GO:0090316 3 0.011
regulation of anatomical structure size GO:0090066 50 0.011
cell death GO:0008219 30 0.011
stress activated protein kinase signaling cascade GO:0031098 4 0.011
negative regulation of cell cycle GO:0045786 91 0.011
positive regulation of cellular component organization GO:0051130 116 0.011
response to heat GO:0009408 69 0.011
death GO:0016265 30 0.011
regulation of dna templated transcription in response to stress GO:0043620 51 0.011
establishment of protein localization to mitochondrion GO:0072655 63 0.011
polysaccharide metabolic process GO:0005976 60 0.011
amine metabolic process GO:0009308 51 0.011
cation transport GO:0006812 166 0.011
nucleotide catabolic process GO:0009166 330 0.011
glycoprotein metabolic process GO:0009100 62 0.011
ribonucleoside triphosphate catabolic process GO:0009203 327 0.010
endoplasmic reticulum organization GO:0007029 30 0.010
nuclear import GO:0051170 57 0.010
regulation of metal ion transport GO:0010959 2 0.010
maintenance of protein location GO:0045185 53 0.010
positive regulation of cytoplasmic transport GO:1903651 4 0.010
spore wall assembly GO:0042244 52 0.010

PDI1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017