Saccharomyces cerevisiae

44 known processes

NHX1 (YDR456W)

Nhx1p

(Aliases: VPS44,NHA2,VPL27)

NHX1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 166 0.937
cation homeostasis GO:0055080 105 0.857
cellular cation homeostasis GO:0030003 100 0.841
metal ion homeostasis GO:0055065 79 0.821
ion transport GO:0006811 274 0.783
ion homeostasis GO:0050801 118 0.744
inorganic cation transmembrane transport GO:0098662 98 0.656
cellular homeostasis GO:0019725 138 0.631
ion transmembrane transport GO:0034220 200 0.570
cellular metal ion homeostasis GO:0006875 78 0.549
transmembrane transport GO:0055085 349 0.498
transition metal ion transport GO:0000041 45 0.494
metal ion transport GO:0030001 75 0.481
chemical homeostasis GO:0048878 137 0.459
cellular chemical homeostasis GO:0055082 123 0.454
cellular ion homeostasis GO:0006873 112 0.404
cellular divalent inorganic cation homeostasis GO:0072503 21 0.358
membrane lipid metabolic process GO:0006643 67 0.328
cellular transition metal ion homeostasis GO:0046916 59 0.304
regulation of biological quality GO:0065008 391 0.254
inorganic ion transmembrane transport GO:0098660 109 0.210
generation of precursor metabolites and energy GO:0006091 147 0.208
vacuolar transport GO:0007034 145 0.191
divalent inorganic cation homeostasis GO:0072507 21 0.180
cation transmembrane transport GO:0098655 135 0.163
liposaccharide metabolic process GO:1903509 31 0.143
homeostatic process GO:0042592 227 0.120
monovalent inorganic cation homeostasis GO:0055067 32 0.116
divalent metal ion transport GO:0070838 17 0.114
cellular iron ion homeostasis GO:0006879 34 0.112
anion transport GO:0006820 145 0.107
carbohydrate transport GO:0008643 33 0.099
energy derivation by oxidation of organic compounds GO:0015980 125 0.098
anion transmembrane transport GO:0098656 79 0.097
monovalent inorganic cation transport GO:0015672 78 0.096
proteolysis GO:0006508 268 0.090
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.086
positive regulation of nucleic acid templated transcription GO:1903508 286 0.085
organic acid transport GO:0015849 77 0.082
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.082
divalent inorganic cation transport GO:0072511 26 0.081
cellular monovalent inorganic cation homeostasis GO:0030004 27 0.081
positive regulation of transcription dna templated GO:0045893 286 0.079
regulation of protein metabolic process GO:0051246 237 0.079
organic acid metabolic process GO:0006082 352 0.075
glycolipid metabolic process GO:0006664 31 0.073
single organism catabolic process GO:0044712 619 0.070
phospholipid metabolic process GO:0006644 125 0.070
organophosphate metabolic process GO:0019637 597 0.067
modification dependent macromolecule catabolic process GO:0043632 203 0.065
cellular response to starvation GO:0009267 90 0.064
alcohol metabolic process GO:0006066 112 0.063
regulation of molecular function GO:0065009 320 0.059
carbohydrate derivative metabolic process GO:1901135 549 0.058
iron ion homeostasis GO:0055072 34 0.057
regulation of phosphorus metabolic process GO:0051174 230 0.052
glycerophospholipid metabolic process GO:0006650 98 0.050
regulation of catalytic activity GO:0050790 307 0.050
developmental process GO:0032502 261 0.048
alpha amino acid metabolic process GO:1901605 124 0.048
cellular amino acid metabolic process GO:0006520 225 0.048
amino acid transport GO:0006865 45 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.048
detection of stimulus GO:0051606 4 0.047
cofactor biosynthetic process GO:0051188 80 0.046
modification dependent protein catabolic process GO:0019941 181 0.046
regulation of response to stimulus GO:0048583 157 0.045
carbohydrate metabolic process GO:0005975 252 0.045
response to organic cyclic compound GO:0014070 1 0.044
regulation of cellular protein metabolic process GO:0032268 232 0.044
positive regulation of macromolecule metabolic process GO:0010604 394 0.043
lipoprotein biosynthetic process GO:0042158 40 0.042
lipid biosynthetic process GO:0008610 170 0.041
positive regulation of cellular biosynthetic process GO:0031328 336 0.041
lipoprotein metabolic process GO:0042157 40 0.041
cellular response to nutrient levels GO:0031669 144 0.040
response to nutrient levels GO:0031667 150 0.040
heterocycle catabolic process GO:0046700 494 0.040
regulation of cell communication GO:0010646 124 0.039
response to inorganic substance GO:0010035 47 0.039
cellular response to extracellular stimulus GO:0031668 150 0.038
proteasomal protein catabolic process GO:0010498 141 0.037
protein lipidation GO:0006497 40 0.037
response to oxidative stress GO:0006979 99 0.036
gpi anchor biosynthetic process GO:0006506 26 0.034
actin filament based process GO:0030029 104 0.033
purine containing compound catabolic process GO:0072523 332 0.033
regulation of phosphate metabolic process GO:0019220 230 0.033
response to extracellular stimulus GO:0009991 156 0.033
regulation of phosphorylation GO:0042325 86 0.032
membrane lipid biosynthetic process GO:0046467 54 0.031
signal transduction GO:0007165 208 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.030
sulfur compound metabolic process GO:0006790 95 0.030
positive regulation of gene expression GO:0010628 321 0.030
vesicle mediated transport GO:0016192 335 0.029
hydrogen transport GO:0006818 61 0.028
cellular response to external stimulus GO:0071496 150 0.027
copper ion import GO:0015677 8 0.027
endosomal transport GO:0016197 86 0.027
response to external stimulus GO:0009605 158 0.027
actin cytoskeleton organization GO:0030036 100 0.027
sphingolipid metabolic process GO:0006665 41 0.027
negative regulation of organelle organization GO:0010639 103 0.026
response to ph GO:0009268 18 0.026
nucleoside triphosphate metabolic process GO:0009141 364 0.026
cellular developmental process GO:0048869 191 0.026
developmental process involved in reproduction GO:0003006 159 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.026
purine nucleotide metabolic process GO:0006163 376 0.026
regulation of dna replication GO:0006275 51 0.026
protein maturation GO:0051604 76 0.026
nitrogen compound transport GO:0071705 212 0.026
positive regulation of catalytic activity GO:0043085 178 0.026
nucleobase containing small molecule metabolic process GO:0055086 491 0.025
growth GO:0040007 157 0.025
regulation of organelle organization GO:0033043 243 0.025
positive regulation of biosynthetic process GO:0009891 336 0.025
intracellular protein transport GO:0006886 319 0.025
positive regulation of rna metabolic process GO:0051254 294 0.025
sphingolipid biosynthetic process GO:0030148 29 0.025
organic cyclic compound catabolic process GO:1901361 499 0.025
regulation of ph GO:0006885 21 0.024
regulation of signal transduction GO:0009966 114 0.024
ribonucleotide metabolic process GO:0009259 377 0.024
cellular lipid metabolic process GO:0044255 229 0.024
oxidation reduction process GO:0055114 353 0.024
protein processing GO:0016485 64 0.024
positive regulation of apoptotic process GO:0043065 3 0.024
reproductive process in single celled organism GO:0022413 145 0.024
regulation of cellular component organization GO:0051128 334 0.023
mitochondrion organization GO:0007005 261 0.023
sporulation GO:0043934 132 0.023
response to starvation GO:0042594 96 0.023
oxoacid metabolic process GO:0043436 351 0.023
ribonucleoside metabolic process GO:0009119 389 0.023
alpha amino acid biosynthetic process GO:1901607 91 0.023
anatomical structure morphogenesis GO:0009653 160 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.022
sulfur compound transport GO:0072348 19 0.022
macroautophagy GO:0016236 55 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.022
single organism carbohydrate metabolic process GO:0044723 237 0.022
cytoskeleton organization GO:0007010 230 0.022
calcium ion homeostasis GO:0055074 9 0.022
macromolecule catabolic process GO:0009057 383 0.022
organophosphate catabolic process GO:0046434 338 0.022
aromatic compound catabolic process GO:0019439 491 0.021
coenzyme biosynthetic process GO:0009108 66 0.021
organonitrogen compound biosynthetic process GO:1901566 314 0.021
signaling GO:0023052 208 0.021
positive regulation of cell death GO:0010942 3 0.021
cellular protein catabolic process GO:0044257 213 0.021
positive regulation of rna biosynthetic process GO:1902680 286 0.020
dna replication GO:0006260 147 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
autophagy GO:0006914 106 0.020
regulation of catabolic process GO:0009894 199 0.020
glycosyl compound catabolic process GO:1901658 335 0.020
aging GO:0007568 71 0.020
cellular macromolecule catabolic process GO:0044265 363 0.019
response to chemical GO:0042221 390 0.019
cellular respiration GO:0045333 82 0.019
establishment or maintenance of cell polarity GO:0007163 96 0.019
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.019
inorganic anion transport GO:0015698 30 0.019
negative regulation of cell communication GO:0010648 33 0.019
nucleoside metabolic process GO:0009116 394 0.019
ribonucleoside catabolic process GO:0042454 332 0.019
ascospore wall biogenesis GO:0070591 52 0.019
single organism cellular localization GO:1902580 375 0.019
positive regulation of programmed cell death GO:0043068 3 0.019
late endosome to vacuole transport GO:0045324 42 0.019
single organism developmental process GO:0044767 258 0.018
carboxylic acid transport GO:0046942 74 0.018
regulation of cellular catabolic process GO:0031329 195 0.018
purine nucleoside triphosphate catabolic process GO:0009146 329 0.018
negative regulation of macromolecule metabolic process GO:0010605 375 0.018
hexose transport GO:0008645 24 0.018
anatomical structure development GO:0048856 160 0.018
response to abiotic stimulus GO:0009628 159 0.018
meiotic cell cycle GO:0051321 272 0.018
response to hypoxia GO:0001666 4 0.018
positive regulation of molecular function GO:0044093 185 0.018
purine ribonucleoside catabolic process GO:0046130 330 0.018
phospholipid biosynthetic process GO:0008654 89 0.018
organonitrogen compound catabolic process GO:1901565 404 0.017
intracellular signal transduction GO:0035556 112 0.017
negative regulation of cellular metabolic process GO:0031324 407 0.017
response to metal ion GO:0010038 24 0.017
phosphorylation GO:0016310 291 0.017
sulfur compound biosynthetic process GO:0044272 53 0.017
nucleotide metabolic process GO:0009117 453 0.017
regulation of signaling GO:0023051 119 0.016
nucleoside phosphate metabolic process GO:0006753 458 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.016
cellular carbohydrate metabolic process GO:0044262 135 0.016
positive regulation of protein metabolic process GO:0051247 93 0.016
carbohydrate derivative biosynthetic process GO:1901137 181 0.016
cellular response to oxidative stress GO:0034599 94 0.016
glycerolipid biosynthetic process GO:0045017 71 0.015
ncrna processing GO:0034470 330 0.015
regulation of hydrolase activity GO:0051336 133 0.015
ribonucleoside triphosphate catabolic process GO:0009203 327 0.015
aerobic respiration GO:0009060 55 0.015
regulation of localization GO:0032879 127 0.015
small molecule catabolic process GO:0044282 88 0.015
cellular carbohydrate catabolic process GO:0044275 33 0.014
ribose phosphate metabolic process GO:0019693 384 0.014
single organism membrane fusion GO:0044801 71 0.014
negative regulation of cellular component organization GO:0051129 109 0.014
negative regulation of protein modification process GO:0031400 37 0.014
negative regulation of catabolic process GO:0009895 43 0.014
cell wall assembly GO:0070726 54 0.014
anatomical structure formation involved in morphogenesis GO:0048646 136 0.014
membrane organization GO:0061024 276 0.014
reproductive process GO:0022414 248 0.014
glycolipid biosynthetic process GO:0009247 28 0.014
cellular amine metabolic process GO:0044106 51 0.014
sodium ion transport GO:0006814 9 0.014
nucleotide catabolic process GO:0009166 330 0.014
transition metal ion homeostasis GO:0055076 59 0.014
negative regulation of response to stimulus GO:0048585 40 0.014
peptidyl amino acid modification GO:0018193 116 0.014
protein ubiquitination GO:0016567 118 0.013
cellular response to acidic ph GO:0071468 4 0.013
glucose transport GO:0015758 23 0.013
ubiquitin dependent protein catabolic process GO:0006511 181 0.013
copper ion transport GO:0006825 16 0.013
multi organism process GO:0051704 233 0.013
protein transport GO:0015031 345 0.013
cell communication GO:0007154 345 0.013
purine nucleoside metabolic process GO:0042278 380 0.013
polyol metabolic process GO:0019751 22 0.013
sporulation resulting in formation of a cellular spore GO:0030435 129 0.013
protein targeting GO:0006605 272 0.013
reactive oxygen species metabolic process GO:0072593 10 0.013
phosphatidylinositol biosynthetic process GO:0006661 39 0.012
ribonucleoside triphosphate metabolic process GO:0009199 356 0.012
single organism reproductive process GO:0044702 159 0.012
organelle inheritance GO:0048308 51 0.012
purine ribonucleotide metabolic process GO:0009150 372 0.012
purine ribonucleoside metabolic process GO:0046128 380 0.012
positive regulation of transcription from rna polymerase ii promoter in response to acidic ph GO:0061402 4 0.012
cell aging GO:0007569 70 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.012
regulation of purine nucleotide metabolic process GO:1900542 109 0.012
glycosyl compound metabolic process GO:1901657 398 0.012
sexual reproduction GO:0019953 216 0.012
trna metabolic process GO:0006399 151 0.011
protein phosphorylation GO:0006468 197 0.011
cellular amide metabolic process GO:0043603 59 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.011
regulation of cellular component biogenesis GO:0044087 112 0.011
dna repair GO:0006281 236 0.011
meiotic nuclear division GO:0007126 163 0.011
nucleoside catabolic process GO:0009164 335 0.011
protein localization to organelle GO:0033365 337 0.011
nucleobase containing compound catabolic process GO:0034655 479 0.011
positive regulation of phosphorus metabolic process GO:0010562 147 0.011
detection of chemical stimulus GO:0009593 3 0.011
regulation of generation of precursor metabolites and energy GO:0043467 23 0.011
regulation of cellular ph GO:0030641 17 0.011
nucleoside monophosphate catabolic process GO:0009125 224 0.011
regulation of response to external stimulus GO:0032101 20 0.011
single organism signaling GO:0044700 208 0.011
carbohydrate derivative catabolic process GO:1901136 339 0.011
regulation of nucleoside metabolic process GO:0009118 106 0.011
negative regulation of signal transduction GO:0009968 30 0.010
spore wall assembly GO:0042244 52 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
establishment of protein localization to organelle GO:0072594 278 0.010
regulation of protein modification process GO:0031399 110 0.010

NHX1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011