Saccharomyces cerevisiae

70 known processes

PIL1 (YGR086C)

Pil1p

PIL1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein kinase activity GO:0045859 67 0.977
regulation of kinase activity GO:0043549 71 0.965
regulation of transferase activity GO:0051338 83 0.961
protein phosphorylation GO:0006468 197 0.959
negative regulation of protein phosphorylation GO:0001933 24 0.937
negative regulation of phosphorylation GO:0042326 28 0.919
regulation of protein modification process GO:0031399 110 0.903
negative regulation of macromolecule metabolic process GO:0010605 375 0.884
regulation of cellular protein metabolic process GO:0032268 232 0.839
cellular response to dna damage stimulus GO:0006974 287 0.696
single organism cellular localization GO:1902580 375 0.687
negative regulation of molecular function GO:0044092 68 0.664
regulation of protein metabolic process GO:0051246 237 0.610
regulation of protein phosphorylation GO:0001932 75 0.588
regulation of phosphorus metabolic process GO:0051174 230 0.569
single organism membrane organization GO:0044802 275 0.554
negative regulation of cellular metabolic process GO:0031324 407 0.552
regulation of response to stimulus GO:0048583 157 0.537
negative regulation of transferase activity GO:0051348 31 0.523
anatomical structure development GO:0048856 160 0.521
phosphorylation GO:0016310 291 0.492
sporulation GO:0043934 132 0.492
dna recombination GO:0006310 172 0.477
negative regulation of cellular protein metabolic process GO:0032269 85 0.472
regulation of response to stress GO:0080134 57 0.470
regulation of phosphate metabolic process GO:0019220 230 0.441
dna repair GO:0006281 236 0.436
negative regulation of protein kinase activity GO:0006469 23 0.416
regulation of protein serine threonine kinase activity GO:0071900 41 0.381
negative regulation of cellular component organization GO:0051129 109 0.371
signal transduction GO:0007165 208 0.361
response to abiotic stimulus GO:0009628 159 0.353
protein transport GO:0015031 345 0.300
chromatin modification GO:0016568 200 0.296
developmental process GO:0032502 261 0.296
regulation of phosphorylation GO:0042325 86 0.287
membrane organization GO:0061024 276 0.284
single organism developmental process GO:0044767 258 0.272
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.268
response to chemical GO:0042221 390 0.262
meiotic cell cycle GO:0051321 272 0.246
intracellular signal transduction GO:0035556 112 0.244
regulation of molecular function GO:0065009 320 0.240
mapk cascade GO:0000165 30 0.236
cellular response to chemical stimulus GO:0070887 315 0.235
establishment of protein localization GO:0045184 367 0.224
anatomical structure morphogenesis GO:0009653 160 0.224
regulation of cellular component organization GO:0051128 334 0.218
mitotic cell cycle process GO:1903047 294 0.205
negative regulation of gene expression GO:0010629 312 0.200
cellular lipid metabolic process GO:0044255 229 0.196
multi organism cellular process GO:0044764 120 0.196
negative regulation of phosphate metabolic process GO:0045936 49 0.193
protein complex assembly GO:0006461 302 0.192
cellular developmental process GO:0048869 191 0.191
signaling GO:0023052 208 0.189
cell communication GO:0007154 345 0.188
secretion GO:0046903 50 0.183
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.170
peptidyl amino acid modification GO:0018193 116 0.166
positive regulation of cellular component organization GO:0051130 116 0.165
sexual reproduction GO:0019953 216 0.165
double strand break repair GO:0006302 105 0.163
signal transduction by phosphorylation GO:0023014 31 0.161
negative regulation of dna metabolic process GO:0051053 36 0.161
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.159
multi organism reproductive process GO:0044703 216 0.151
cell aging GO:0007569 70 0.145
vesicle mediated transport GO:0016192 335 0.142
actin filament based process GO:0030029 104 0.141
negative regulation of kinase activity GO:0033673 24 0.139
conjugation with cellular fusion GO:0000747 106 0.132
organelle fission GO:0048285 272 0.131
anatomical structure formation involved in morphogenesis GO:0048646 136 0.130
regulation of cellular component biogenesis GO:0044087 112 0.126
carbohydrate biosynthetic process GO:0016051 82 0.125
negative regulation of phosphorus metabolic process GO:0010563 49 0.123
regulation of catalytic activity GO:0050790 307 0.111
regulation of cell cycle GO:0051726 195 0.111
cell wall biogenesis GO:0042546 93 0.111
negative regulation of organelle organization GO:0010639 103 0.109
reproductive process GO:0022414 248 0.109
endosomal transport GO:0016197 86 0.108
negative regulation of protein modification process GO:0031400 37 0.108
protein targeting GO:0006605 272 0.107
cellular carbohydrate biosynthetic process GO:0034637 49 0.106
regulation of biological quality GO:0065008 391 0.103
negative regulation of intracellular signal transduction GO:1902532 27 0.103
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.102
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.100
lipid metabolic process GO:0006629 269 0.098
regulation of localization GO:0032879 127 0.098
actin cytoskeleton organization GO:0030036 100 0.096
regulation of intracellular signal transduction GO:1902531 78 0.095
organonitrogen compound biosynthetic process GO:1901566 314 0.095
positive regulation of protein phosphorylation GO:0001934 28 0.094
ion transport GO:0006811 274 0.091
chromatin organization GO:0006325 242 0.086
negative regulation of transcription dna templated GO:0045892 258 0.084
negative regulation of cellular biosynthetic process GO:0031327 312 0.084
regulation of signal transduction GO:0009966 114 0.083
mrna processing GO:0006397 185 0.081
cytoskeleton organization GO:0007010 230 0.080
nucleobase containing small molecule metabolic process GO:0055086 491 0.080
regulation of dna metabolic process GO:0051052 100 0.079
external encapsulating structure organization GO:0045229 146 0.077
secretion by cell GO:0032940 50 0.076
lipid catabolic process GO:0016042 33 0.076
regulation of protein localization GO:0032880 62 0.074
cell differentiation GO:0030154 161 0.073
regulation of mitotic cell cycle GO:0007346 107 0.071
mrna catabolic process GO:0006402 93 0.070
regulation of cellular component size GO:0032535 50 0.070
aging GO:0007568 71 0.067
regulation of cellular response to stress GO:0080135 50 0.066
cell cycle dna replication GO:0044786 36 0.066
regulation of meiotic cell cycle GO:0051445 43 0.064
cell cycle g1 s phase transition GO:0044843 64 0.063
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.061
intracellular protein transport GO:0006886 319 0.061
regulation of protein polymerization GO:0032271 33 0.060
programmed cell death GO:0012501 30 0.059
establishment of protein localization to organelle GO:0072594 278 0.058
death GO:0016265 30 0.057
cellular component movement GO:0006928 20 0.057
meiotic cell cycle process GO:1903046 229 0.055
negative regulation of response to stimulus GO:0048585 40 0.055
regulation of transport GO:0051049 85 0.055
cellular response to organic substance GO:0071310 159 0.054
maintenance of location GO:0051235 66 0.052
regulation of organelle organization GO:0033043 243 0.051
nucleoside phosphate metabolic process GO:0006753 458 0.051
response to pheromone GO:0019236 92 0.050
mitotic cell cycle GO:0000278 306 0.050
mrna 3 end processing GO:0031124 54 0.050
cellular macromolecule catabolic process GO:0044265 363 0.050
negative regulation of catalytic activity GO:0043086 60 0.050
ascospore formation GO:0030437 107 0.048
sporulation resulting in formation of a cellular spore GO:0030435 129 0.047
cell wall organization or biogenesis GO:0071554 190 0.046
transmembrane transport GO:0055085 349 0.046
actin filament organization GO:0007015 56 0.046
organophosphate metabolic process GO:0019637 597 0.046
regulation of cellular catabolic process GO:0031329 195 0.045
cellular nitrogen compound catabolic process GO:0044270 494 0.044
carboxylic acid biosynthetic process GO:0046394 152 0.043
cellular response to oxygen containing compound GO:1901701 43 0.043
filamentous growth of a population of unicellular organisms GO:0044182 109 0.042
negative regulation of protein metabolic process GO:0051248 85 0.042
positive regulation of phosphorylation GO:0042327 33 0.041
positive regulation of intracellular transport GO:0032388 4 0.040
cellular component disassembly GO:0022411 86 0.040
positive regulation of cellular protein metabolic process GO:0032270 89 0.039
endocytosis GO:0006897 90 0.037
cellular response to oxidative stress GO:0034599 94 0.037
purine nucleoside triphosphate catabolic process GO:0009146 329 0.035
cell growth GO:0016049 89 0.035
cell cycle phase transition GO:0044770 144 0.035
establishment of organelle localization GO:0051656 96 0.034
positive regulation of protein modification process GO:0031401 49 0.034
cell death GO:0008219 30 0.034
histone modification GO:0016570 119 0.033
microtubule based process GO:0007017 117 0.032
cellular component morphogenesis GO:0032989 97 0.032
macromolecular complex disassembly GO:0032984 80 0.032
nuclear division GO:0000280 263 0.031
response to osmotic stress GO:0006970 83 0.031
anatomical structure homeostasis GO:0060249 74 0.031
apoptotic process GO:0006915 30 0.030
response to organic substance GO:0010033 182 0.030
response to heat GO:0009408 69 0.030
single organism catabolic process GO:0044712 619 0.029
mitochondrion organization GO:0007005 261 0.029
positive regulation of phosphorus metabolic process GO:0010562 147 0.028
maintenance of protein location GO:0045185 53 0.028
dna conformation change GO:0071103 98 0.028
lipid biosynthetic process GO:0008610 170 0.028
purine ribonucleotide metabolic process GO:0009150 372 0.026
positive regulation of organelle organization GO:0010638 85 0.025
organelle assembly GO:0070925 118 0.025
filamentous growth GO:0030447 124 0.025
positive regulation of cell death GO:0010942 3 0.025
aromatic compound catabolic process GO:0019439 491 0.024
reproductive process in single celled organism GO:0022413 145 0.024
dna dependent dna replication GO:0006261 115 0.024
sexual sporulation GO:0034293 113 0.024
chromatin remodeling GO:0006338 80 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.024
negative regulation of nucleic acid templated transcription GO:1903507 260 0.024
protein complex biogenesis GO:0070271 314 0.024
protein localization to organelle GO:0033365 337 0.023
positive regulation of cytoplasmic transport GO:1903651 4 0.023
carbohydrate derivative metabolic process GO:1901135 549 0.023
organelle localization GO:0051640 128 0.023
regulation of protein complex assembly GO:0043254 77 0.023
positive regulation of programmed cell death GO:0043068 3 0.023
positive regulation of protein kinase activity GO:0045860 22 0.023
cellular lipid catabolic process GO:0044242 33 0.023
fungal type cell wall organization GO:0031505 145 0.023
positive regulation of transport GO:0051050 32 0.023
response to drug GO:0042493 41 0.023
negative regulation of rna biosynthetic process GO:1902679 260 0.023
multi organism process GO:0051704 233 0.023
regulation of cell cycle process GO:0010564 150 0.023
regulation of cellular localization GO:0060341 50 0.023
nucleoside phosphate catabolic process GO:1901292 331 0.023
homeostatic process GO:0042592 227 0.023
regulation of vesicle mediated transport GO:0060627 39 0.022
organonitrogen compound catabolic process GO:1901565 404 0.022
autophagy GO:0006914 106 0.022
eisosome assembly GO:0070941 8 0.022
ribonucleoside metabolic process GO:0009119 389 0.022
purine nucleotide metabolic process GO:0006163 376 0.022
protein polymerization GO:0051258 51 0.021
cell morphogenesis GO:0000902 30 0.021
positive regulation of intracellular protein transport GO:0090316 3 0.021
negative regulation of rna metabolic process GO:0051253 262 0.021
meiotic nuclear division GO:0007126 163 0.021
positive regulation of molecular function GO:0044093 185 0.021
cellular protein catabolic process GO:0044257 213 0.020
maintenance of location in cell GO:0051651 58 0.020
nuclear transport GO:0051169 165 0.020
negative regulation of cell cycle GO:0045786 91 0.020
ras protein signal transduction GO:0007265 29 0.020
biological adhesion GO:0022610 14 0.020
regulation of cell communication GO:0010646 124 0.020
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.020
purine ribonucleotide catabolic process GO:0009154 327 0.019
nucleoside triphosphate metabolic process GO:0009141 364 0.019
nucleotide catabolic process GO:0009166 330 0.019
negative regulation of protein depolymerization GO:1901880 12 0.019
cell division GO:0051301 205 0.019
organic cyclic compound catabolic process GO:1901361 499 0.019
ribonucleoprotein complex assembly GO:0022618 143 0.019
reproduction of a single celled organism GO:0032505 191 0.019
rna 3 end processing GO:0031123 88 0.019
protein complex disassembly GO:0043241 70 0.018
negative regulation of biosynthetic process GO:0009890 312 0.018
negative regulation of gene expression epigenetic GO:0045814 147 0.018
response to oxidative stress GO:0006979 99 0.018
conjugation GO:0000746 107 0.018
regulation of intracellular transport GO:0032386 26 0.018
positive regulation of protein metabolic process GO:0051247 93 0.017
positive regulation of catabolic process GO:0009896 135 0.017
recombinational repair GO:0000725 64 0.017
positive regulation of catalytic activity GO:0043085 178 0.017
ribose phosphate metabolic process GO:0019693 384 0.017
growth GO:0040007 157 0.016
dna integrity checkpoint GO:0031570 41 0.016
protein import GO:0017038 122 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.015
negative regulation of cell communication GO:0010648 33 0.015
phospholipid metabolic process GO:0006644 125 0.015
regulation of anatomical structure size GO:0090066 50 0.015
nucleoside monophosphate metabolic process GO:0009123 267 0.015
protein localization to membrane GO:0072657 102 0.015
organophosphate biosynthetic process GO:0090407 182 0.015
metal ion transport GO:0030001 75 0.014
positive regulation of kinase activity GO:0033674 24 0.014
maintenance of protein location in cell GO:0032507 50 0.014
regulation of establishment of protein localization GO:0070201 17 0.014
negative regulation of signaling GO:0023057 30 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.013
organic hydroxy compound biosynthetic process GO:1901617 81 0.013
single organism membrane fusion GO:0044801 71 0.013
macromolecule catabolic process GO:0009057 383 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.013
ribonucleoside catabolic process GO:0042454 332 0.013
response to temperature stimulus GO:0009266 74 0.013
positive regulation of cell cycle GO:0045787 32 0.013
cellular response to endogenous stimulus GO:0071495 22 0.013
dna damage checkpoint GO:0000077 29 0.013
cell adhesion GO:0007155 14 0.013
reactive oxygen species metabolic process GO:0072593 10 0.013
ribonucleoside triphosphate metabolic process GO:0009199 356 0.013
oxoacid metabolic process GO:0043436 351 0.013
cellular response to starvation GO:0009267 90 0.013
response to organic cyclic compound GO:0014070 1 0.013
nucleoside triphosphate catabolic process GO:0009143 329 0.013
carbohydrate derivative catabolic process GO:1901136 339 0.013
lipid modification GO:0030258 37 0.012
positive regulation of transferase activity GO:0051347 28 0.012
developmental process involved in reproduction GO:0003006 159 0.012
replicative cell aging GO:0001302 46 0.012
mrna metabolic process GO:0016071 269 0.012
negative regulation of cell cycle process GO:0010948 86 0.012
alcohol metabolic process GO:0006066 112 0.012
regulation of catabolic process GO:0009894 199 0.012
regulation of developmental process GO:0050793 30 0.012
regulation of programmed cell death GO:0043067 8 0.012
endomembrane system organization GO:0010256 74 0.012
purine ribonucleoside metabolic process GO:0046128 380 0.012
ribonucleoprotein complex subunit organization GO:0071826 152 0.012
chromatin silencing GO:0006342 147 0.012
cell development GO:0048468 107 0.012
positive regulation of phosphate metabolic process GO:0045937 147 0.012
nucleoside monophosphate catabolic process GO:0009125 224 0.012
regulation of cytoplasmic transport GO:1903649 24 0.011
regulation of lipid metabolic process GO:0019216 45 0.011
mitotic cell cycle phase transition GO:0044772 141 0.011
positive regulation of cellular component biogenesis GO:0044089 45 0.011
cation homeostasis GO:0055080 105 0.011
small molecule biosynthetic process GO:0044283 258 0.011
purine containing compound catabolic process GO:0072523 332 0.011
nucleoside metabolic process GO:0009116 394 0.011
positive regulation of cellular catabolic process GO:0031331 128 0.011
establishment or maintenance of cell polarity GO:0007163 96 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
single organism reproductive process GO:0044702 159 0.010
nucleus organization GO:0006997 62 0.010
regulation of gene expression epigenetic GO:0040029 147 0.010
nucleotide metabolic process GO:0009117 453 0.010
ribonucleoside monophosphate catabolic process GO:0009158 224 0.010
amine metabolic process GO:0009308 51 0.010

PIL1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org