Saccharomyces cerevisiae

135 known processes

MAD2 (YJL030W)

Mad2p

MAD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.987
regulation of mitotic sister chromatid separation GO:0010965 29 0.979
regulation of chromosome segregation GO:0051983 44 0.975
regulation of sister chromatid segregation GO:0033045 30 0.959
mitotic spindle assembly checkpoint GO:0007094 23 0.959
ubiquitin dependent protein catabolic process GO:0006511 181 0.955
regulation of mitotic metaphase anaphase transition GO:0030071 27 0.954
regulation of mitotic sister chromatid segregation GO:0033047 30 0.952
modification dependent protein catabolic process GO:0019941 181 0.948
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.944
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 24 0.944
negative regulation of mitotic sister chromatid separation GO:2000816 23 0.941
mitotic sister chromatid separation GO:0051306 26 0.940
sister chromatid segregation GO:0000819 93 0.936
regulation of metaphase anaphase transition of cell cycle GO:1902099 27 0.934
negative regulation of mitotic metaphase anaphase transition GO:0045841 23 0.927
metaphase anaphase transition of cell cycle GO:0044784 28 0.917
mitotic sister chromatid segregation GO:0000070 85 0.915
negative regulation of sister chromatid segregation GO:0033046 24 0.908
modification dependent macromolecule catabolic process GO:0043632 203 0.901
regulation of mitosis GO:0007088 65 0.900
negative regulation of chromosome segregation GO:0051985 25 0.890
negative regulation of mitotic sister chromatid segregation GO:0033048 24 0.885
macromolecule catabolic process GO:0009057 383 0.857
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.850
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.848
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.845
chromosome separation GO:0051304 33 0.844
protein catabolic process GO:0030163 221 0.841
chromosome segregation GO:0007059 159 0.837
mitotic cell cycle checkpoint GO:0007093 56 0.831
spindle checkpoint GO:0031577 35 0.813
negative regulation of mitosis GO:0045839 39 0.801
proteasomal protein catabolic process GO:0010498 141 0.796
cellular protein catabolic process GO:0044257 213 0.769
negative regulation of protein maturation GO:1903318 33 0.763
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.702
cellular macromolecule catabolic process GO:0044265 363 0.698
negative regulation of cellular catabolic process GO:0031330 43 0.693
regulation of chromosome organization GO:0033044 66 0.691
proteolysis GO:0006508 268 0.649
regulation of proteasomal protein catabolic process GO:0061136 34 0.645
negative regulation of cellular protein catabolic process GO:1903363 27 0.641
regulation of protein catabolic process GO:0042176 40 0.637
negative regulation of catabolic process GO:0009895 43 0.598
mitotic spindle checkpoint GO:0071174 34 0.580
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.569
spindle assembly checkpoint GO:0071173 23 0.562
regulation of protein maturation GO:1903317 34 0.553
regulation of cellular protein catabolic process GO:1903362 36 0.546
negative regulation of protein catabolic process GO:0042177 27 0.526
mitotic nuclear division GO:0007067 131 0.516
microtubule cytoskeleton organization GO:0000226 109 0.488
protein processing GO:0016485 64 0.482
negative regulation of proteolysis GO:0045861 33 0.481
regulation of mitotic cell cycle phase transition GO:1901990 68 0.481
cell cycle phase transition GO:0044770 144 0.476
regulation of cell cycle phase transition GO:1901987 70 0.460
mitotic cell cycle GO:0000278 306 0.450
meiotic chromosome segregation GO:0045132 31 0.422
cell cycle checkpoint GO:0000075 82 0.421
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 23 0.420
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.406
regulation of nuclear division GO:0051783 103 0.402
negative regulation of protein processing GO:0010955 33 0.401
regulation of protein metabolic process GO:0051246 237 0.399
organelle fission GO:0048285 272 0.393
mitotic cell cycle process GO:1903047 294 0.384
regulation of cellular component organization GO:0051128 334 0.379
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.362
negative regulation of chromosome organization GO:2001251 39 0.362
negative regulation of protein metabolic process GO:0051248 85 0.332
cell division GO:0051301 205 0.326
regulation of cell cycle GO:0051726 195 0.324
cytoskeleton organization GO:0007010 230 0.322
microtubule based process GO:0007017 117 0.311
negative regulation of cell cycle phase transition GO:1901988 59 0.299
regulation of cell cycle process GO:0010564 150 0.276
negative regulation of mitotic cell cycle GO:0045930 63 0.267
regulation of protein processing GO:0070613 34 0.267
mitotic cell cycle phase transition GO:0044772 141 0.263
regulation of cellular protein metabolic process GO:0032268 232 0.260
negative regulation of cellular metabolic process GO:0031324 407 0.246
regulation of cell division GO:0051302 113 0.244
negative regulation of cellular protein metabolic process GO:0032269 85 0.243
single organism catabolic process GO:0044712 619 0.230
negative regulation of nuclear division GO:0051784 62 0.218
nuclear division GO:0000280 263 0.204
regulation of proteolysis GO:0030162 44 0.203
regulation of cellular catabolic process GO:0031329 195 0.199
meiosis i GO:0007127 92 0.199
negative regulation of organelle organization GO:0010639 103 0.191
meiotic cell cycle process GO:1903046 229 0.187
negative regulation of cell division GO:0051782 66 0.186
protein maturation GO:0051604 76 0.177
negative regulation of macromolecule metabolic process GO:0010605 375 0.169
protein localization to organelle GO:0033365 337 0.165
protein dna complex assembly GO:0065004 105 0.157
meiotic cell cycle GO:0051321 272 0.147
regulation of organelle organization GO:0033043 243 0.144
negative regulation of cell cycle process GO:0010948 86 0.133
regulation of catabolic process GO:0009894 199 0.122
regulation of mitotic cell cycle GO:0007346 107 0.120
negative regulation of gene expression GO:0010629 312 0.119
meiotic nuclear division GO:0007126 163 0.116
protein dna complex subunit organization GO:0071824 153 0.111
protein complex biogenesis GO:0070271 314 0.109
single organism membrane organization GO:0044802 275 0.101
attachment of spindle microtubules to kinetochore GO:0008608 25 0.084
establishment of protein localization to organelle GO:0072594 278 0.079
protein targeting GO:0006605 272 0.079
membrane organization GO:0061024 276 0.077
protein transport GO:0015031 345 0.075
dna integrity checkpoint GO:0031570 41 0.074
intracellular protein transport GO:0006886 319 0.074
single organism cellular localization GO:1902580 375 0.068
mitotic metaphase plate congression GO:0007080 8 0.068
regulation of meiotic cell cycle GO:0051445 43 0.065
sexual reproduction GO:0019953 216 0.058
mitotic dna integrity checkpoint GO:0044774 18 0.057
regulation of biological quality GO:0065008 391 0.057
negative regulation of cellular component organization GO:0051129 109 0.055
response to chemical GO:0042221 390 0.055
chromosome organization involved in meiosis GO:0070192 32 0.054
cellular protein complex assembly GO:0043623 209 0.052
organelle localization GO:0051640 128 0.049
establishment of organelle localization GO:0051656 96 0.045
positive regulation of cell cycle process GO:0090068 31 0.045
Human
protein ubiquitination GO:0016567 118 0.045
Human
negative regulation of cell cycle GO:0045786 91 0.044
aromatic compound catabolic process GO:0019439 491 0.043
protein complex disassembly GO:0043241 70 0.042
sister chromatid cohesion GO:0007062 49 0.042
maintenance of location in cell GO:0051651 58 0.041
nucleobase containing compound catabolic process GO:0034655 479 0.040
regulation of microtubule based process GO:0032886 32 0.039
positive regulation of cellular component organization GO:0051130 116 0.037
single organism reproductive process GO:0044702 159 0.036
response to organic cyclic compound GO:0014070 1 0.034
cell differentiation GO:0030154 161 0.033
cellular glucan metabolic process GO:0006073 44 0.032
regulation of molecular function GO:0065009 320 0.032
Human
mitotic sister chromatid cohesion GO:0007064 38 0.032
macromolecular complex disassembly GO:0032984 80 0.032
negative regulation of biosynthetic process GO:0009890 312 0.032
g2 m transition of mitotic cell cycle GO:0000086 38 0.031
posttranscriptional regulation of gene expression GO:0010608 115 0.031
positive regulation of cell cycle GO:0045787 32 0.030
Human
autophagy GO:0006914 106 0.030
establishment of protein localization GO:0045184 367 0.030
microtubule anchoring GO:0034453 25 0.027
cell cycle g2 m phase transition GO:0044839 39 0.027
heterocycle catabolic process GO:0046700 494 0.026
sporulation resulting in formation of a cellular spore GO:0030435 129 0.026
protein complex assembly GO:0006461 302 0.025
centromere complex assembly GO:0034508 8 0.025
cellular nitrogen compound catabolic process GO:0044270 494 0.025
maintenance of protein location in cell GO:0032507 50 0.025
protein modification by small protein conjugation or removal GO:0070647 172 0.025
Human
purine containing compound catabolic process GO:0072523 332 0.024
spindle organization GO:0007051 37 0.023
maintenance of location GO:0051235 66 0.023
reciprocal meiotic recombination GO:0007131 54 0.023
response to abiotic stimulus GO:0009628 159 0.023
chromosome localization GO:0050000 20 0.022
phosphorylation GO:0016310 291 0.022
positive regulation of organelle organization GO:0010638 85 0.021
cellular response to chemical stimulus GO:0070887 315 0.021
cellular component disassembly GO:0022411 86 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.020
Human
protein targeting to nucleus GO:0044744 57 0.020
mitotic spindle organization GO:0007052 30 0.020
developmental process GO:0032502 261 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 13 0.020
positive regulation of catabolic process GO:0009896 135 0.020
single organism developmental process GO:0044767 258 0.020
ascospore formation GO:0030437 107 0.020
developmental process involved in reproduction GO:0003006 159 0.019
establishment of sister chromatid cohesion GO:0034085 17 0.019
positive regulation of protein metabolic process GO:0051247 93 0.019
organic cyclic compound catabolic process GO:1901361 499 0.019
protein modification by small protein conjugation GO:0032446 144 0.018
Human
regulation of protein localization GO:0032880 62 0.017
mrna processing GO:0006397 185 0.017
dna replication GO:0006260 147 0.017
maintenance of protein location GO:0045185 53 0.017
response to organic substance GO:0010033 182 0.017
regulation of catalytic activity GO:0050790 307 0.016
Human
positive regulation of mitotic cell cycle GO:0045931 16 0.016
Human
spindle assembly GO:0051225 9 0.016
regulation of microtubule cytoskeleton organization GO:0070507 32 0.016
microtubule organizing center organization GO:0031023 33 0.016
glucan metabolic process GO:0044042 44 0.016
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.015
cellular response to dna damage stimulus GO:0006974 287 0.015
carbohydrate derivative metabolic process GO:1901135 549 0.015
regulation of dna replication GO:0006275 51 0.015
chromatin remodeling GO:0006338 80 0.015
protein import into nucleus GO:0006606 55 0.015
homeostatic process GO:0042592 227 0.014
mrna 3 end processing GO:0031124 54 0.014
positive regulation of dna templated transcription elongation GO:0032786 42 0.014
negative regulation of protein depolymerization GO:1901880 12 0.014
protein localization to chromosome GO:0034502 28 0.013
protein import GO:0017038 122 0.013
dna dependent dna replication GO:0006261 115 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.013
attachment of mitotic spindle microtubules to kinetochore GO:0051315 9 0.013
protein folding GO:0006457 94 0.013
establishment of mitotic sister chromatid cohesion GO:0034087 15 0.013
positive regulation of protein complex assembly GO:0031334 39 0.012
positive regulation of cellular protein metabolic process GO:0032270 89 0.012
reciprocal dna recombination GO:0035825 54 0.012
regulation of phosphate metabolic process GO:0019220 230 0.012
cellular response to external stimulus GO:0071496 150 0.012
regulation of intracellular transport GO:0032386 26 0.012
regulation of transferase activity GO:0051338 83 0.012
Human
purine nucleoside catabolic process GO:0006152 330 0.012
microtubule based movement GO:0007018 18 0.012
protein localization to chromosome centromeric region GO:0071459 14 0.012
regulation of protein modification process GO:0031399 110 0.012
Human
chemical homeostasis GO:0048878 137 0.011
purine nucleoside triphosphate metabolic process GO:0009144 356 0.011
cell communication GO:0007154 345 0.011
positive regulation of intracellular transport GO:0032388 4 0.011
positive regulation of chromosome organization GO:2001252 20 0.011
mrna metabolic process GO:0016071 269 0.011
regulation of ubiquitin protein transferase activity GO:0051438 8 0.011
Human
cellular response to oxidative stress GO:0034599 94 0.011
positive regulation of catalytic activity GO:0043085 178 0.011
double strand break repair via break induced replication GO:0000727 25 0.011
regulation of cytoskeleton organization GO:0051493 63 0.011
establishment of protein localization to vacuole GO:0072666 91 0.010
dephosphorylation GO:0016311 127 0.010
rna localization GO:0006403 112 0.010
negative regulation of phosphorus metabolic process GO:0010563 49 0.010
regulation of protein localization to nucleus GO:1900180 16 0.010
negative regulation of meiotic cell cycle GO:0051447 24 0.010
vacuolar transport GO:0007034 145 0.010
cellular response to extracellular stimulus GO:0031668 150 0.010
regulation of protein targeting GO:1903533 10 0.010
glycosyl compound metabolic process GO:1901657 398 0.010
cell death GO:0008219 30 0.010
Human

MAD2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org