Saccharomyces cerevisiae

28 known processes

SIS2 (YKR072C)

Sis2p

(Aliases: HAL3)

SIS2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.468
carbohydrate derivative metabolic process GO:1901135 549 0.367
Yeast
homeostatic process GO:0042592 227 0.320
Yeast
cellular ion homeostasis GO:0006873 112 0.310
Yeast
ribonucleoside metabolic process GO:0009119 389 0.303
Yeast
cellular cation homeostasis GO:0030003 100 0.295
Yeast
monovalent inorganic cation homeostasis GO:0055067 32 0.268
Yeast
cellular homeostasis GO:0019725 138 0.261
Yeast
mitotic cell cycle process GO:1903047 294 0.260
cellular monovalent inorganic cation homeostasis GO:0030004 27 0.226
Yeast
cellular chemical homeostasis GO:0055082 123 0.225
Yeast
regulation of biological quality GO:0065008 391 0.221
Yeast
ion homeostasis GO:0050801 118 0.221
Yeast
nucleobase containing small molecule metabolic process GO:0055086 491 0.216
Yeast
chemical homeostasis GO:0048878 137 0.214
Yeast
organonitrogen compound biosynthetic process GO:1901566 314 0.200
Yeast
negative regulation of rna metabolic process GO:0051253 262 0.197
cofactor metabolic process GO:0051186 126 0.190
Yeast
response to osmotic stress GO:0006970 83 0.187
positive regulation of rna metabolic process GO:0051254 294 0.182
organophosphate metabolic process GO:0019637 597 0.176
Yeast
coenzyme metabolic process GO:0006732 104 0.174
Yeast
ribonucleotide metabolic process GO:0009259 377 0.173
Yeast
regulation of mitotic cell cycle GO:0007346 107 0.166
glycosyl compound metabolic process GO:1901657 398 0.163
Yeast
negative regulation of cellular catabolic process GO:0031330 43 0.162
trna processing GO:0008033 101 0.154
cellular macromolecule catabolic process GO:0044265 363 0.154
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.150
purine nucleotide metabolic process GO:0006163 376 0.149
Yeast
negative regulation of rna biosynthetic process GO:1902679 260 0.141
positive regulation of biosynthetic process GO:0009891 336 0.140
proteolysis GO:0006508 268 0.138
modification dependent macromolecule catabolic process GO:0043632 203 0.136
positive regulation of macromolecule metabolic process GO:0010604 394 0.133
protein localization to organelle GO:0033365 337 0.132
cellular protein catabolic process GO:0044257 213 0.131
nucleoside metabolic process GO:0009116 394 0.130
Yeast
purine nucleoside metabolic process GO:0042278 380 0.126
Yeast
purine ribonucleotide metabolic process GO:0009150 372 0.124
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.118
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.118
positive regulation of transcription dna templated GO:0045893 286 0.117
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.117
macromolecule catabolic process GO:0009057 383 0.113
nucleoside phosphate metabolic process GO:0006753 458 0.110
Yeast
positive regulation of cellular biosynthetic process GO:0031328 336 0.109
oxoacid metabolic process GO:0043436 351 0.108
modification dependent protein catabolic process GO:0019941 181 0.108
purine containing compound metabolic process GO:0072521 400 0.104
Yeast
purine ribonucleoside metabolic process GO:0046128 380 0.102
Yeast
gene silencing GO:0016458 151 0.096
mitotic cell cycle GO:0000278 306 0.096
nucleoside biosynthetic process GO:0009163 38 0.094
Yeast
cell cycle phase transition GO:0044770 144 0.080
trna modification GO:0006400 75 0.080
ribose phosphate metabolic process GO:0019693 384 0.080
Yeast
cellular response to chemical stimulus GO:0070887 315 0.079
sexual reproduction GO:0019953 216 0.079
phosphorylation GO:0016310 291 0.077
ribosome biogenesis GO:0042254 335 0.077
carbohydrate derivative catabolic process GO:1901136 339 0.077
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.075
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.074
multi organism reproductive process GO:0044703 216 0.072
negative regulation of cellular metabolic process GO:0031324 407 0.071
vesicle mediated transport GO:0016192 335 0.070
reproductive process GO:0022414 248 0.070
negative regulation of cellular biosynthetic process GO:0031327 312 0.068
conjugation GO:0000746 107 0.068
cofactor biosynthetic process GO:0051188 80 0.068
Yeast
dna replication GO:0006260 147 0.066
protein targeting GO:0006605 272 0.066
single organism catabolic process GO:0044712 619 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.065
nucleotide biosynthetic process GO:0009165 79 0.064
Yeast
generation of precursor metabolites and energy GO:0006091 147 0.064
protein dephosphorylation GO:0006470 40 0.064
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.061
negative regulation of gene expression GO:0010629 312 0.060
regulation of cellular catabolic process GO:0031329 195 0.060
purine ribonucleotide biosynthetic process GO:0009152 39 0.060
Yeast
response to salt stress GO:0009651 34 0.059
regulation of molecular function GO:0065009 320 0.059
positive regulation of rna biosynthetic process GO:1902680 286 0.058
small molecule biosynthetic process GO:0044283 258 0.057
purine nucleoside biosynthetic process GO:0042451 31 0.053
Yeast
ribose phosphate biosynthetic process GO:0046390 50 0.053
Yeast
ubiquitin dependent protein catabolic process GO:0006511 181 0.052
carbohydrate metabolic process GO:0005975 252 0.051
glycosyl compound biosynthetic process GO:1901659 42 0.050
Yeast
alpha amino acid biosynthetic process GO:1901607 91 0.050
negative regulation of macromolecule metabolic process GO:0010605 375 0.049
purine nucleotide biosynthetic process GO:0006164 41 0.049
Yeast
signal transduction GO:0007165 208 0.048
carbohydrate derivative biosynthetic process GO:1901137 181 0.048
Yeast
signaling GO:0023052 208 0.047
protein import GO:0017038 122 0.047
dephosphorylation GO:0016311 127 0.046
energy derivation by oxidation of organic compounds GO:0015980 125 0.046
cation homeostasis GO:0055080 105 0.045
Yeast
positive regulation of gene expression GO:0010628 321 0.044
response to abiotic stimulus GO:0009628 159 0.044
regulation of catalytic activity GO:0050790 307 0.043
protein catabolic process GO:0030163 221 0.043
single organism signaling GO:0044700 208 0.043
conjugation with cellular fusion GO:0000747 106 0.042
negative regulation of transcription dna templated GO:0045892 258 0.042
response to chemical GO:0042221 390 0.042
nitrogen compound transport GO:0071705 212 0.041
organophosphate biosynthetic process GO:0090407 182 0.041
Yeast
multi organism process GO:0051704 233 0.041
nucleoside phosphate biosynthetic process GO:1901293 80 0.041
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 286 0.041
negative regulation of catabolic process GO:0009895 43 0.041
protein localization to nucleus GO:0034504 74 0.039
nucleotide metabolic process GO:0009117 453 0.039
Yeast
mrna metabolic process GO:0016071 269 0.038
alcohol metabolic process GO:0006066 112 0.037
regulation of gene expression epigenetic GO:0040029 147 0.037
regulation of phosphate metabolic process GO:0019220 230 0.036
regulation of protein modification process GO:0031399 110 0.036
single organism cellular localization GO:1902580 375 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.036
negative regulation of nucleic acid templated transcription GO:1903507 260 0.035
purine ribonucleoside biosynthetic process GO:0046129 31 0.035
Yeast
protein processing GO:0016485 64 0.035
glycoprotein metabolic process GO:0009100 62 0.034
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.034
actin cytoskeleton organization GO:0030036 100 0.034
glycosyl compound catabolic process GO:1901658 335 0.034
negative regulation of biosynthetic process GO:0009890 312 0.034
negative regulation of cell communication GO:0010648 33 0.033
nuclear division GO:0000280 263 0.033
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.033
single organism nuclear import GO:1902593 56 0.033
reproductive process in single celled organism GO:0022413 145 0.033
nuclear transport GO:0051169 165 0.032
oxidation reduction process GO:0055114 353 0.031
dna catabolic process GO:0006308 42 0.031
mrna processing GO:0006397 185 0.030
aging GO:0007568 71 0.030
ncrna processing GO:0034470 330 0.029
chromatin silencing GO:0006342 147 0.029
regulation of transferase activity GO:0051338 83 0.029
meiotic cell cycle process GO:1903046 229 0.029
coenzyme biosynthetic process GO:0009108 66 0.029
Yeast
aromatic compound catabolic process GO:0019439 491 0.028
cellular amino acid metabolic process GO:0006520 225 0.028
regulation of catabolic process GO:0009894 199 0.028
carboxylic acid metabolic process GO:0019752 338 0.028
chromatin remodeling GO:0006338 80 0.027
purine ribonucleotide catabolic process GO:0009154 327 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.027
cellular potassium ion homeostasis GO:0030007 6 0.027
mitotic cell cycle phase transition GO:0044772 141 0.027
carboxylic acid biosynthetic process GO:0046394 152 0.027
positive regulation of molecular function GO:0044093 185 0.026
regulation of cellular protein metabolic process GO:0032268 232 0.026
regulation of translation GO:0006417 89 0.026
organelle fission GO:0048285 272 0.026
organic acid biosynthetic process GO:0016053 152 0.026
ion transport GO:0006811 274 0.026
intracellular signal transduction GO:0035556 112 0.025
regulation of cell communication GO:0010646 124 0.025
cellular amino acid biosynthetic process GO:0008652 118 0.025
protein dna complex subunit organization GO:0071824 153 0.025
cellular developmental process GO:0048869 191 0.025
alpha amino acid metabolic process GO:1901605 124 0.025
organic cyclic compound catabolic process GO:1901361 499 0.025
nuclear transcribed mrna catabolic process GO:0000956 89 0.025
carbohydrate catabolic process GO:0016052 77 0.025
organophosphate catabolic process GO:0046434 338 0.024
protein maturation GO:0051604 76 0.024
guanosine containing compound metabolic process GO:1901068 111 0.024
regulation of cell cycle GO:0051726 195 0.024
single organism developmental process GO:0044767 258 0.024
positive regulation of transcription from rna polymerase ii promoter in response to calcium ion GO:0061400 1 0.024
glutamine family amino acid metabolic process GO:0009064 31 0.023
regulation of protein metabolic process GO:0051246 237 0.023
meiotic cell cycle GO:0051321 272 0.022
dna dependent dna replication GO:0006261 115 0.022
regulation of phosphorus metabolic process GO:0051174 230 0.022
g1 s transition of mitotic cell cycle GO:0000082 64 0.022
microtubule polymerization GO:0046785 30 0.022
rna modification GO:0009451 99 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.022
regulation of signaling GO:0023051 119 0.021
protein modification by small protein conjugation or removal GO:0070647 172 0.021
cell cycle g1 s phase transition GO:0044843 64 0.021
purine containing compound biosynthetic process GO:0072522 53 0.021
Yeast
response to organic cyclic compound GO:0014070 1 0.021
actin filament based process GO:0030029 104 0.021
cellular lipid metabolic process GO:0044255 229 0.021
regulation of dna metabolic process GO:0051052 100 0.021
regulation of pseudohyphal growth GO:2000220 18 0.020
coenzyme a biosynthetic process GO:0015937 5 0.020
Yeast
membrane organization GO:0061024 276 0.020
regulation of cellular component organization GO:0051128 334 0.020
anatomical structure morphogenesis GO:0009653 160 0.020
negative regulation of signaling GO:0023057 30 0.019
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.019
sporulation GO:0043934 132 0.019
regulation of mitosis GO:0007088 65 0.019
spindle pole body organization GO:0051300 33 0.019
rna 3 end processing GO:0031123 88 0.019
cellular response to organic substance GO:0071310 159 0.019
cytoskeleton organization GO:0007010 230 0.019
mitotic cytokinesis GO:0000281 58 0.019
lipid biosynthetic process GO:0008610 170 0.019
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 46 0.018
negative regulation of response to stimulus GO:0048585 40 0.018
positive regulation of catabolic process GO:0009896 135 0.018
organic acid catabolic process GO:0016054 71 0.018
regulation of mitotic sister chromatid separation GO:0010965 29 0.018
monocarboxylic acid metabolic process GO:0032787 122 0.018
single organism reproductive process GO:0044702 159 0.018
protein polymerization GO:0051258 51 0.018
purine ribonucleoside catabolic process GO:0046130 330 0.018
regulation of kinase activity GO:0043549 71 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.018
chromatin organization GO:0006325 242 0.018
regulation of dna templated transcription elongation GO:0032784 44 0.018
regulation of mitotic sister chromatid segregation GO:0033047 30 0.017
metaphase anaphase transition of cell cycle GO:0044784 28 0.017
regulation of dna dependent dna replication initiation GO:0030174 21 0.017
ribonucleoside catabolic process GO:0042454 332 0.017
mitotic spindle assembly checkpoint GO:0007094 23 0.017
protein import into nucleus GO:0006606 55 0.017
negative regulation of growth of unicellular organism as a thread of attached cells GO:0070785 11 0.017
regulation of dna replication GO:0006275 51 0.017
negative regulation of protein catabolic process GO:0042177 27 0.017
ribonucleoprotein complex export from nucleus GO:0071426 46 0.017
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 23 0.017
multi organism cellular process GO:0044764 120 0.016
cell communication GO:0007154 345 0.016
pseudohyphal growth GO:0007124 75 0.016
ribonucleoside triphosphate metabolic process GO:0009199 356 0.016
trna metabolic process GO:0006399 151 0.016
negative regulation of gene expression epigenetic GO:0045814 147 0.016
reproduction of a single celled organism GO:0032505 191 0.016
nucleoside phosphate catabolic process GO:1901292 331 0.016
regulation of metaphase anaphase transition of cell cycle GO:1902099 27 0.016
reciprocal meiotic recombination GO:0007131 54 0.016
single organism membrane organization GO:0044802 275 0.016
cellular response to external stimulus GO:0071496 150 0.016
negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from rna polymerase ii promoter GO:1900460 3 0.016
cellular carbohydrate metabolic process GO:0044262 135 0.016
negative regulation of mitotic metaphase anaphase transition GO:0045841 23 0.015
ribonucleoside triphosphate catabolic process GO:0009203 327 0.015
positive regulation of protein metabolic process GO:0051247 93 0.015
posttranscriptional regulation of gene expression GO:0010608 115 0.015
regulation of mitotic metaphase anaphase transition GO:0030071 27 0.015
purine nucleoside triphosphate catabolic process GO:0009146 329 0.015
cell wall organization or biogenesis GO:0071554 190 0.015
establishment of protein localization to organelle GO:0072594 278 0.015
negative regulation of reproductive process GO:2000242 7 0.015
mitotic nuclear division GO:0007067 131 0.015
regulation of multi organism process GO:0043900 20 0.015
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.015
regulation of metal ion transport GO:0010959 2 0.015
negative regulation of mitotic sister chromatid separation GO:2000816 23 0.015
negative regulation of mitotic cell cycle GO:0045930 63 0.015
cell aging GO:0007569 70 0.015
cellular amino acid catabolic process GO:0009063 48 0.014
regulation of conjugation with cellular fusion GO:0031137 16 0.014
nucleosome organization GO:0034728 63 0.014
nucleoside triphosphate catabolic process GO:0009143 329 0.014
negative regulation of molecular function GO:0044092 68 0.014
cell cycle checkpoint GO:0000075 82 0.014
nitrogen utilization GO:0019740 21 0.014
coenzyme a metabolic process GO:0015936 5 0.014
Yeast
dna repair GO:0006281 236 0.014
positive regulation of translation GO:0045727 34 0.014
ribonucleoside bisphosphate biosynthetic process GO:0034030 5 0.014
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 68 0.014
regulation of response to stimulus GO:0048583 157 0.014
mating type determination GO:0007531 32 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
regulation of response to drug GO:2001023 3 0.014
mrna catabolic process GO:0006402 93 0.014
establishment of protein localization GO:0045184 367 0.014
nucleocytoplasmic transport GO:0006913 163 0.014
protein targeting to nucleus GO:0044744 57 0.014
mitotic cell cycle checkpoint GO:0007093 56 0.014
nucleotide catabolic process GO:0009166 330 0.014
peptide metabolic process GO:0006518 28 0.014
nuclear export GO:0051168 124 0.014
negative regulation of cell cycle phase transition GO:1901988 59 0.014
organelle assembly GO:0070925 118 0.013
organic acid metabolic process GO:0006082 352 0.013
translation GO:0006412 230 0.013
regulation of conjugation GO:0046999 16 0.013
ribonucleotide biosynthetic process GO:0009260 44 0.013
Yeast
alcohol biosynthetic process GO:0046165 75 0.013
protein localization to membrane GO:0072657 102 0.013
cellular response to topologically incorrect protein GO:0035967 32 0.013
meiotic nuclear division GO:0007126 163 0.013
response to carbohydrate GO:0009743 14 0.013
regulation of protein processing GO:0070613 34 0.013
cellular component morphogenesis GO:0032989 97 0.013
positive regulation of hydrolase activity GO:0051345 112 0.013
rna localization GO:0006403 112 0.013
response to freezing GO:0050826 4 0.013
regulation of carbohydrate metabolic process GO:0006109 43 0.013
ribonucleoprotein complex localization GO:0071166 46 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.013
response to organic substance GO:0010033 182 0.013
regulation of dna recombination GO:0000018 24 0.013
negative regulation of chromosome segregation GO:0051985 25 0.013
regulation of generation of precursor metabolites and energy GO:0043467 23 0.012
cellular response to anoxia GO:0071454 3 0.012
anion transport GO:0006820 145 0.012
microtubule organizing center organization GO:0031023 33 0.012
mapk cascade GO:0000165 30 0.012
regulation of dna templated transcription in response to stress GO:0043620 51 0.012
negative regulation of sister chromatid segregation GO:0033046 24 0.012
negative regulation of mitotic sister chromatid segregation GO:0033048 24 0.012
single organism carbohydrate catabolic process GO:0044724 73 0.012
regulation of reproductive process GO:2000241 24 0.012
cell differentiation GO:0030154 161 0.012
cellular component disassembly GO:0022411 86 0.012
dna templated transcription termination GO:0006353 42 0.012
rrna metabolic process GO:0016072 244 0.012
nucleobase containing compound catabolic process GO:0034655 479 0.012
acetate biosynthetic process GO:0019413 4 0.012
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 26 0.012
ergosterol biosynthetic process GO:0006696 29 0.012
lipid metabolic process GO:0006629 269 0.012
metal ion homeostasis GO:0055065 79 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
regulation of protein catabolic process GO:0042176 40 0.012
positive regulation of sulfite transport GO:1900072 1 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.012
negative regulation of multi organism process GO:0043901 6 0.012
cellular hypotonic response GO:0071476 2 0.012
heterocycle catabolic process GO:0046700 494 0.012
chromatin modification GO:0016568 200 0.012
response to blue light GO:0009637 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 147 0.012
negative regulation of catalytic activity GO:0043086 60 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.011
ribonucleoprotein complex assembly GO:0022618 143 0.011
regulation of cell division GO:0051302 113 0.011
mitotic sister chromatid separation GO:0051306 26 0.011
mitotic spindle checkpoint GO:0071174 34 0.011
cellular carbohydrate catabolic process GO:0044275 33 0.011
filamentous growth GO:0030447 124 0.011
phospholipid metabolic process GO:0006644 125 0.011
regulation of cellular response to drug GO:2001038 3 0.011
proteasomal protein catabolic process GO:0010498 141 0.011
organonitrogen compound catabolic process GO:1901565 404 0.011
developmental process GO:0032502 261 0.011
macromolecular complex disassembly GO:0032984 80 0.011
amine metabolic process GO:0009308 51 0.011
anatomical structure homeostasis GO:0060249 74 0.011
regulation of homeostatic process GO:0032844 19 0.011
replicative cell aging GO:0001302 46 0.011
cell surface receptor signaling pathway GO:0007166 38 0.011
anatomical structure development GO:0048856 160 0.011
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage GO:0010767 1 0.011
signal transduction by phosphorylation GO:0023014 31 0.011
positive regulation of cytoplasmic transport GO:1903651 4 0.011
purine nucleoside catabolic process GO:0006152 330 0.011
chromatin silencing at silent mating type cassette GO:0030466 53 0.011
regulation of chromosome organization GO:0033044 66 0.011
dna damage checkpoint GO:0000077 29 0.011
regulation of dna dependent dna replication GO:0090329 37 0.011
ribonucleotide catabolic process GO:0009261 327 0.011
double strand break repair via nonhomologous end joining GO:0006303 27 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.011
cellular response to pheromone GO:0071444 88 0.011
misfolded or incompletely synthesized protein catabolic process GO:0006515 21 0.011
regulation of ribosomal protein gene transcription from rna polymerase ii promoter GO:0060962 10 0.011
small molecule catabolic process GO:0044282 88 0.011
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.011
negative regulation of chromosome organization GO:2001251 39 0.011
negative regulation of cellular response to alkaline ph by negative regulation of transcription from rna polymerase ii promoter GO:1900463 1 0.010
regulation of small gtpase mediated signal transduction GO:0051056 47 0.010
regulation of localization GO:0032879 127 0.010
sulfur compound biosynthetic process GO:0044272 53 0.010
positive regulation of catalytic activity GO:0043085 178 0.010
response to temperature stimulus GO:0009266 74 0.010
regulation of cellular component biogenesis GO:0044087 112 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.010
positive regulation of transcription from rna polymerase ii promoter in response to a hypotonic environment GO:0061401 2 0.010
dna templated transcription elongation GO:0006354 91 0.010
regulation of cell cycle phase transition GO:1901987 70 0.010
negative regulation of protein processing GO:0010955 33 0.010
response to heat GO:0009408 69 0.010
negative regulation of cell cycle process GO:0010948 86 0.010

SIS2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017