|
protein targeting
|
GO:0006605 |
272 |
1.000
|
|
|
vacuolar transport
|
GO:0007034 |
145 |
0.998
|
|
|
protein localization to vacuole
|
GO:0072665 |
92 |
0.998
|
|
|
establishment of protein localization to vacuole
|
GO:0072666 |
91 |
0.997
|
|
|
protein targeting to vacuole
|
GO:0006623 |
91 |
0.996
|
|
|
intracellular protein transport
|
GO:0006886 |
319 |
0.995
|
|
|
protein transport
|
GO:0015031 |
345 |
0.995
|
|
|
vesicle mediated transport
|
GO:0016192 |
335 |
0.989
|
|
|
single organism cellular localization
|
GO:1902580 |
375 |
0.987
|
|
|
protein localization to organelle
|
GO:0033365 |
337 |
0.985
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
278 |
0.977
|
|
|
establishment of protein localization
|
GO:0045184 |
367 |
0.958
|
|
|
endosomal transport
|
GO:0016197 |
86 |
0.951
|
|
|
golgi vesicle transport
|
GO:0048193 |
188 |
0.905
|
|
|
vacuole organization
|
GO:0007033 |
75 |
0.885
|
|
|
vesicle fusion
|
GO:0006906 |
33 |
0.853
|
Fly |
|
endocytosis
|
GO:0006897 |
90 |
0.800
|
|
|
regulation of cellular component organization
|
GO:0051128 |
334 |
0.791
|
Human Zebrafish Mouse Fly |
|
late endosome to vacuole transport
|
GO:0045324 |
42 |
0.774
|
|
|
single organism membrane fusion
|
GO:0044801 |
71 |
0.754
|
Fly |
|
carbohydrate derivative metabolic process
|
GO:1901135 |
549 |
0.719
|
|
|
vesicle organization
|
GO:0016050 |
68 |
0.713
|
Fly |
|
organelle fusion
|
GO:0048284 |
85 |
0.678
|
Fly |
|
cell communication
|
GO:0007154 |
345 |
0.667
|
Human Fly |
|
late endosome to vacuole transport via multivesicular body sorting pathway
|
GO:0032511 |
26 |
0.658
|
|
|
single organism membrane organization
|
GO:0044802 |
275 |
0.647
|
Fly |
|
negative regulation of cellular metabolic process
|
GO:0031324 |
407 |
0.606
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
27 |
0.600
|
|
|
secretion
|
GO:0046903 |
50 |
0.585
|
Human |
|
secretion by cell
|
GO:0032940 |
50 |
0.573
|
Human |
|
membrane organization
|
GO:0061024 |
276 |
0.541
|
Fly |
|
ribonucleoside metabolic process
|
GO:0009119 |
389 |
0.529
|
|
|
single organism catabolic process
|
GO:0044712 |
619 |
0.517
|
|
|
membrane fusion
|
GO:0061025 |
73 |
0.500
|
Fly |
|
protein targeting to membrane
|
GO:0006612 |
52 |
0.478
|
|
|
signaling
|
GO:0023052 |
208 |
0.475
|
Human Fly |
|
post golgi vesicle mediated transport
|
GO:0006892 |
72 |
0.472
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
327 |
0.439
|
|
|
organelle inheritance
|
GO:0048308 |
51 |
0.415
|
|
|
regulation of signaling
|
GO:0023051 |
119 |
0.406
|
Human |
|
ribose phosphate metabolic process
|
GO:0019693 |
384 |
0.403
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.398
|
|
|
piecemeal microautophagy of nucleus
|
GO:0034727 |
33 |
0.387
|
|
|
golgi to endosome transport
|
GO:0006895 |
17 |
0.364
|
|
|
single organism signaling
|
GO:0044700 |
208 |
0.350
|
Human Fly |
|
exocytosis
|
GO:0006887 |
42 |
0.344
|
Human |
|
establishment of protein localization to membrane
|
GO:0090150 |
99 |
0.327
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
356 |
0.315
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
230 |
0.301
|
|
|
gtp catabolic process
|
GO:0006184 |
107 |
0.299
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
39 |
0.292
|
Human Zebrafish Mouse Fly |
|
cellular protein catabolic process
|
GO:0044257 |
213 |
0.288
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
479 |
0.264
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
377 |
0.253
|
|
|
regulation of localization
|
GO:0032879 |
127 |
0.231
|
Human Zebrafish Mouse Fly |
|
purine nucleoside metabolic process
|
GO:0042278 |
380 |
0.228
|
|
|
organophosphate catabolic process
|
GO:0046434 |
338 |
0.223
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
354 |
0.221
|
|
|
microautophagy
|
GO:0016237 |
43 |
0.216
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
364 |
0.210
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
376 |
0.206
|
|
|
signal transduction
|
GO:0007165 |
208 |
0.198
|
Human |
|
ribonucleoside catabolic process
|
GO:0042454 |
332 |
0.192
|
|
|
regulation of cell communication
|
GO:0010646 |
124 |
0.187
|
Human |
|
vacuole fusion non autophagic
|
GO:0042144 |
40 |
0.184
|
|
|
macromolecule catabolic process
|
GO:0009057 |
383 |
0.183
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
327 |
0.182
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
312 |
0.182
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
111 |
0.175
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
300 |
0.169
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
375 |
0.164
|
|
|
nucleoside catabolic process
|
GO:0009164 |
335 |
0.162
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
230 |
0.159
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
339 |
0.158
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
331 |
0.156
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
327 |
0.156
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
372 |
0.155
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
329 |
0.148
|
|
|
organophosphate metabolic process
|
GO:0019637 |
597 |
0.147
|
|
|
macroautophagy
|
GO:0016236 |
55 |
0.146
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
330 |
0.141
|
|
|
response to extracellular stimulus
|
GO:0009991 |
156 |
0.138
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
380 |
0.137
|
|
|
gtp metabolic process
|
GO:0046039 |
107 |
0.135
|
|
|
proteolysis
|
GO:0006508 |
268 |
0.133
|
|
|
autophagy
|
GO:0006914 |
106 |
0.130
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
112 |
0.129
|
Human |
|
purine containing compound catabolic process
|
GO:0072523 |
332 |
0.128
|
|
|
protein localization to membrane
|
GO:0072657 |
102 |
0.126
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
335 |
0.126
|
|
|
regulation of organelle organization
|
GO:0033043 |
243 |
0.123
|
|
|
regulation of transport
|
GO:0051049 |
85 |
0.122
|
Human Zebrafish Mouse Fly |
|
glycosyl compound metabolic process
|
GO:1901657 |
398 |
0.115
|
|
|
organelle assembly
|
GO:0070925 |
118 |
0.112
|
|
|
response to starvation
|
GO:0042594 |
96 |
0.108
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
356 |
0.107
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
2 |
0.106
|
Human |
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
494 |
0.102
|
|
|
endomembrane system organization
|
GO:0010256 |
74 |
0.102
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
327 |
0.101
|
|
|
nucleophagy
|
GO:0044804 |
34 |
0.101
|
|
|
regulation of cellular localization
|
GO:0060341 |
50 |
0.100
|
Human |
|
early endosome to late endosome transport
|
GO:0045022 |
1 |
0.092
|
Human |
|
nucleotide catabolic process
|
GO:0009166 |
330 |
0.091
|
|
|
vacuole fusion
|
GO:0097576 |
40 |
0.090
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
328 |
0.088
|
|
|
response to nutrient levels
|
GO:0031667 |
150 |
0.087
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
363 |
0.084
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
181 |
0.083
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
49 |
0.081
|
|
|
intracellular signal transduction
|
GO:0035556 |
112 |
0.081
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
330 |
0.079
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
198 |
0.072
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
312 |
0.072
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
491 |
0.071
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
491 |
0.070
|
|
|
regulation of biological quality
|
GO:0065008 |
391 |
0.066
|
Human Fly |
|
nucleoside metabolic process
|
GO:0009116 |
394 |
0.065
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
49 |
0.062
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
195 |
0.061
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
400 |
0.061
|
|
|
protein ubiquitination
|
GO:0016567 |
118 |
0.059
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
109 |
0.058
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
404 |
0.057
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
499 |
0.055
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
329 |
0.055
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
147 |
0.054
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
458 |
0.051
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.051
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
124 |
0.050
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
80 |
0.049
|
|
|
vacuole inheritance
|
GO:0000011 |
16 |
0.049
|
|
|
single organism membrane invagination
|
GO:1902534 |
43 |
0.048
|
|
|
cellular response to starvation
|
GO:0009267 |
90 |
0.048
|
|
|
phospholipid metabolic process
|
GO:0006644 |
125 |
0.045
|
|
|
regulation of exocytosis
|
GO:0017157 |
5 |
0.042
|
Human |
|
cellular response to chemical stimulus
|
GO:0070887 |
315 |
0.041
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
78 |
0.040
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
2 |
0.040
|
Human |
|
regulation of catabolic process
|
GO:0009894 |
199 |
0.039
|
|
|
cellular response to external stimulus
|
GO:0071496 |
150 |
0.038
|
|
|
cellular monovalent inorganic cation homeostasis
|
GO:0030004 |
27 |
0.038
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
150 |
0.038
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
40 |
0.038
|
|
|
vesicle docking
|
GO:0048278 |
16 |
0.037
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
30 |
0.036
|
|
|
negative regulation of cell communication
|
GO:0010648 |
33 |
0.036
|
|
|
anatomical structure development
|
GO:0048856 |
160 |
0.036
|
Zebrafish Fly |
|
chromatin organization
|
GO:0006325 |
242 |
0.036
|
Fly |
|
cvt pathway
|
GO:0032258 |
37 |
0.035
|
|
|
receptor metabolic process
|
GO:0043112 |
8 |
0.034
|
Human |
|
cellular developmental process
|
GO:0048869 |
191 |
0.033
|
Fly |
|
chromatin silencing
|
GO:0006342 |
147 |
0.033
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
144 |
0.032
|
|
|
response to chemical
|
GO:0042221 |
390 |
0.032
|
|
|
mitotic cell cycle process
|
GO:1903047 |
294 |
0.031
|
Fly |
|
carbohydrate metabolic process
|
GO:0005975 |
252 |
0.031
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
172 |
0.031
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
143 |
0.031
|
|
|
membrane docking
|
GO:0022406 |
22 |
0.030
|
|
|
positive regulation of secretion
|
GO:0051047 |
2 |
0.030
|
Human |
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.029
|
|
|
regulation of gtpase activity
|
GO:0043087 |
84 |
0.028
|
|
|
multi organism cellular process
|
GO:0044764 |
120 |
0.028
|
|
|
response to abiotic stimulus
|
GO:0009628 |
159 |
0.028
|
|
|
autophagic vacuole assembly
|
GO:0000045 |
16 |
0.028
|
|
|
positive regulation of transport
|
GO:0051050 |
32 |
0.026
|
Human |
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
203 |
0.026
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
47 |
0.026
|
|
|
membrane invagination
|
GO:0010324 |
43 |
0.026
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
295 |
0.025
|
|
|
protein complex disassembly
|
GO:0043241 |
70 |
0.025
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
394 |
0.025
|
|
|
regulation of cellular component size
|
GO:0032535 |
50 |
0.024
|
Human |
|
nucleotide metabolic process
|
GO:0009117 |
453 |
0.024
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
84 |
0.024
|
|
|
regulation of vacuole fusion non autophagic
|
GO:0032889 |
14 |
0.023
|
|
|
negative regulation of signaling
|
GO:0023057 |
30 |
0.023
|
|
|
regulation of gene silencing
|
GO:0060968 |
41 |
0.023
|
|
|
heterocycle catabolic process
|
GO:0046700 |
494 |
0.022
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
314 |
0.022
|
|
|
multi organism process
|
GO:0051704 |
233 |
0.022
|
Fly |
|
regulation of ras protein signal transduction
|
GO:0046578 |
47 |
0.021
|
|
|
regulation of vacuole organization
|
GO:0044088 |
20 |
0.020
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
232 |
0.019
|
|
|
regulation of endocytosis
|
GO:0030100 |
17 |
0.019
|
Zebrafish Mouse Fly |
|
protein acylation
|
GO:0043543 |
66 |
0.019
|
|
|
filamentous growth of a population of unicellular organisms
|
GO:0044182 |
109 |
0.019
|
|
|
filamentous growth
|
GO:0030447 |
124 |
0.019
|
|
|
regulation of response to stimulus
|
GO:0048583 |
157 |
0.018
|
|
|
regulation of response to stress
|
GO:0080134 |
57 |
0.018
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
63 |
0.018
|
|
|
protein complex assembly
|
GO:0006461 |
302 |
0.017
|
|
|
nitrogen compound transport
|
GO:0071705 |
212 |
0.017
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
133 |
0.017
|
|
|
multi organism reproductive process
|
GO:0044703 |
216 |
0.017
|
Fly |
|
cellular response to organic substance
|
GO:0071310 |
159 |
0.017
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
97 |
0.017
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
260 |
0.017
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
258 |
0.016
|
|
|
regulation of catalytic activity
|
GO:0050790 |
307 |
0.016
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
106 |
0.016
|
|
|
response to external stimulus
|
GO:0009605 |
158 |
0.016
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
89 |
0.016
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
137 |
0.016
|
|
|
telomere maintenance
|
GO:0000723 |
74 |
0.015
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
32 |
0.015
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
181 |
0.015
|
|
|
cellular response to heat
|
GO:0034605 |
53 |
0.015
|
|
|
response to temperature stimulus
|
GO:0009266 |
74 |
0.015
|
|
|
cellular response to nutrient
|
GO:0031670 |
50 |
0.014
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
39 |
0.014
|
|
|
response to organic substance
|
GO:0010033 |
182 |
0.014
|
|
|
cellular component disassembly
|
GO:0022411 |
86 |
0.014
|
|
|
rna transport
|
GO:0050658 |
92 |
0.014
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
41 |
0.014
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
144 |
0.014
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
106 |
0.014
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
37 |
0.013
|
|
|
mitotic cell cycle
|
GO:0000278 |
306 |
0.013
|
Fly |
|
vacuolar acidification
|
GO:0007035 |
16 |
0.012
|
|
|
meiotic cell cycle
|
GO:0051321 |
272 |
0.012
|
Fly |
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
63 |
0.012
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
237 |
0.012
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
77 |
0.012
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
82 |
0.012
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
409 |
0.012
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
109 |
0.012
|
|
|
cell division
|
GO:0051301 |
205 |
0.012
|
|
|
regulation of macroautophagy
|
GO:0016241 |
15 |
0.011
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
115 |
0.011
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
32 |
0.011
|
|
|
regulation of ph
|
GO:0006885 |
21 |
0.011
|
|
|
maintenance of location
|
GO:0051235 |
66 |
0.011
|
|
|
cell projection assembly
|
GO:0030031 |
8 |
0.011
|
Human |
|
lipid metabolic process
|
GO:0006629 |
269 |
0.011
|
|
|
single organism developmental process
|
GO:0044767 |
258 |
0.010
|
Zebrafish Fly |
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
38 |
0.010
|
|
|
ncrna processing
|
GO:0034470 |
330 |
0.010
|
|