Saccharomyces cerevisiae

121 known processes

MCM4 (YPR019W)

Mcm4p

(Aliases: CDC54,HCD21)

MCM4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication GO:0006260 147 0.998
recombinational repair GO:0000725 64 0.998
double strand break repair via break induced replication GO:0000727 25 0.996
dna replication initiation GO:0006270 48 0.996
dna dependent dna replication GO:0006261 115 0.994
dna recombination GO:0006310 172 0.992
double strand break repair via homologous recombination GO:0000724 54 0.974
cellular response to dna damage stimulus GO:0006974 287 0.963
double strand break repair GO:0006302 105 0.949
dna strand elongation involved in dna replication GO:0006271 26 0.927
dna duplex unwinding GO:0032508 42 0.924
cell cycle dna replication GO:0044786 36 0.910
dna geometric change GO:0032392 43 0.900
dna repair GO:0006281 236 0.889
dna unwinding involved in dna replication GO:0006268 13 0.806
protein dna complex assembly GO:0065004 105 0.739
regulation of dna dependent dna replication initiation GO:0030174 21 0.730
pre replicative complex assembly GO:0036388 20 0.719
dna strand elongation GO:0022616 29 0.597
protein dna complex subunit organization GO:0071824 153 0.586
nuclear dna replication GO:0033260 27 0.585
pre replicative complex assembly involved in nuclear cell cycle dna replication GO:0006267 20 0.573
pre replicative complex assembly involved in cell cycle dna replication GO:1902299 20 0.561
mitotic cell cycle process GO:1903047 294 0.540
Fly
dna conformation change GO:0071103 98 0.530
single organism signaling GO:0044700 208 0.525
signaling GO:0023052 208 0.408
regulation of cell cycle GO:0051726 195 0.366
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.318
cell differentiation GO:0030154 161 0.314
single organism developmental process GO:0044767 258 0.299
meiotic cell cycle GO:0051321 272 0.280
mitotic cell cycle GO:0000278 306 0.277
Fly
purine containing compound metabolic process GO:0072521 400 0.274
cell communication GO:0007154 345 0.255
regulation of cell cycle process GO:0010564 150 0.247
single organism catabolic process GO:0044712 619 0.216
developmental process GO:0032502 261 0.212
cell cycle phase transition GO:0044770 144 0.209
meiotic cell cycle process GO:1903046 229 0.193
nuclear division GO:0000280 263 0.185
regulation of dna metabolic process GO:0051052 100 0.183
negative regulation of cellular metabolic process GO:0031324 407 0.181
mitotic cell cycle phase transition GO:0044772 141 0.172
organelle fission GO:0048285 272 0.167
purine nucleoside metabolic process GO:0042278 380 0.165
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.164
negative regulation of cell division GO:0051782 66 0.163
heterocycle catabolic process GO:0046700 494 0.150
negative regulation of cell cycle phase transition GO:1901988 59 0.146
cellular nitrogen compound catabolic process GO:0044270 494 0.146
carbohydrate derivative metabolic process GO:1901135 549 0.144
negative regulation of cell cycle GO:0045786 91 0.141
oxoacid metabolic process GO:0043436 351 0.139
regulation of phosphorylation GO:0042325 86 0.139
purine ribonucleotide metabolic process GO:0009150 372 0.138
cellular developmental process GO:0048869 191 0.138
ribonucleoside metabolic process GO:0009119 389 0.136
glycosyl compound metabolic process GO:1901657 398 0.135
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.133
nucleobase containing small molecule metabolic process GO:0055086 491 0.130
negative regulation of cell cycle process GO:0010948 86 0.126
protein complex assembly GO:0006461 302 0.124
regulation of mitotic cell cycle GO:0007346 107 0.123
chromatin silencing at telomere GO:0006348 84 0.122
reciprocal dna recombination GO:0035825 54 0.116
nucleoside phosphate metabolic process GO:0006753 458 0.110
negative regulation of transcription dna templated GO:0045892 258 0.110
ribonucleoside triphosphate metabolic process GO:0009199 356 0.110
negative regulation of mitotic cell cycle GO:0045930 63 0.109
organic acid metabolic process GO:0006082 352 0.109
purine nucleotide metabolic process GO:0006163 376 0.107
dna integrity checkpoint GO:0031570 41 0.107
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.107
regulation of cellular component organization GO:0051128 334 0.106
phosphorylation GO:0016310 291 0.106
ribonucleotide metabolic process GO:0009259 377 0.102
regulation of biological quality GO:0065008 391 0.101
chromosome condensation GO:0030261 19 0.101
gene silencing GO:0016458 151 0.100
cell cycle checkpoint GO:0000075 82 0.096
negative regulation of biosynthetic process GO:0009890 312 0.096
multi organism reproductive process GO:0044703 216 0.095
nucleoside catabolic process GO:0009164 335 0.090
glycosyl compound catabolic process GO:1901658 335 0.089
dna damage checkpoint GO:0000077 29 0.089
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.086
ribonucleoside monophosphate metabolic process GO:0009161 265 0.083
regulation of mitotic cell cycle phase transition GO:1901990 68 0.081
mitotic dna integrity checkpoint GO:0044774 18 0.080
nucleobase containing compound catabolic process GO:0034655 479 0.078
response to chemical GO:0042221 390 0.078
regulation of phosphorus metabolic process GO:0051174 230 0.076
regulation of dna replication GO:0006275 51 0.076
organic cyclic compound catabolic process GO:1901361 499 0.076
negative regulation of cellular component organization GO:0051129 109 0.076
aromatic compound catabolic process GO:0019439 491 0.075
purine nucleoside catabolic process GO:0006152 330 0.074
regulation of phosphate metabolic process GO:0019220 230 0.074
regulation of cellular component biogenesis GO:0044087 112 0.073
nucleotide metabolic process GO:0009117 453 0.072
positive regulation of cellular component organization GO:0051130 116 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.070
cellular amino acid metabolic process GO:0006520 225 0.070
negative regulation of nucleic acid templated transcription GO:1903507 260 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.066
negative regulation of dna metabolic process GO:0051053 36 0.066
negative regulation of macromolecule metabolic process GO:0010605 375 0.066
carboxylic acid metabolic process GO:0019752 338 0.066
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.065
purine nucleoside triphosphate metabolic process GO:0009144 356 0.063
homeostatic process GO:0042592 227 0.062
reproductive process GO:0022414 248 0.062
positive regulation of macromolecule metabolic process GO:0010604 394 0.062
response to organic substance GO:0010033 182 0.062
signal transduction GO:0007165 208 0.062
regulation of chromatin silencing at telomere GO:0031938 27 0.061
regulation of molecular function GO:0065009 320 0.061
nucleoside metabolic process GO:0009116 394 0.059
protein complex biogenesis GO:0070271 314 0.059
nucleoside triphosphate catabolic process GO:0009143 329 0.058
positive regulation of rna metabolic process GO:0051254 294 0.057
regulation of dna dependent dna replication GO:0090329 37 0.057
ribonucleoside triphosphate catabolic process GO:0009203 327 0.057
g1 s transition of mitotic cell cycle GO:0000082 64 0.057
organonitrogen compound catabolic process GO:1901565 404 0.055
nucleotide catabolic process GO:0009166 330 0.054
negative regulation of gene expression epigenetic GO:0045814 147 0.053
cellular response to chemical stimulus GO:0070887 315 0.053
reciprocal meiotic recombination GO:0007131 54 0.053
atp metabolic process GO:0046034 251 0.052
purine ribonucleoside metabolic process GO:0046128 380 0.050
regulation of protein complex assembly GO:0043254 77 0.048
purine nucleotide catabolic process GO:0006195 328 0.048
chromatin assembly GO:0031497 35 0.047
protein phosphorylation GO:0006468 197 0.046
positive regulation of protein phosphorylation GO:0001934 28 0.046
chromosome segregation GO:0007059 159 0.046
positive regulation of biosynthetic process GO:0009891 336 0.046
positive regulation of nucleic acid templated transcription GO:1903508 286 0.045
mitotic nuclear division GO:0007067 131 0.045
chromatin silencing at silent mating type cassette GO:0030466 53 0.044
regulation of gene silencing GO:0060968 41 0.044
multi organism process GO:0051704 233 0.043
purine nucleoside monophosphate metabolic process GO:0009126 262 0.043
purine ribonucleotide catabolic process GO:0009154 327 0.043
negative regulation of cellular biosynthetic process GO:0031327 312 0.043
regulation of signaling GO:0023051 119 0.042
chromatin assembly or disassembly GO:0006333 60 0.042
ribonucleoside catabolic process GO:0042454 332 0.042
negative regulation of rna biosynthetic process GO:1902679 260 0.041
nucleoside monophosphate metabolic process GO:0009123 267 0.041
sexual reproduction GO:0019953 216 0.040
organophosphate catabolic process GO:0046434 338 0.040
regulation of gene expression epigenetic GO:0040029 147 0.040
cellular response to organic substance GO:0071310 159 0.039
dna packaging GO:0006323 55 0.039
small molecule biosynthetic process GO:0044283 258 0.039
negative regulation of rna metabolic process GO:0051253 262 0.039
carbohydrate derivative catabolic process GO:1901136 339 0.038
negative regulation of cellular catabolic process GO:0031330 43 0.037
cellular amino acid biosynthetic process GO:0008652 118 0.036
negative regulation of chromatin silencing at telomere GO:0031939 15 0.036
regulation of purine nucleotide metabolic process GO:1900542 109 0.035
positive regulation of cell cycle process GO:0090068 31 0.035
regulation of nucleotide catabolic process GO:0030811 106 0.035
nucleoside monophosphate catabolic process GO:0009125 224 0.035
reproduction of a single celled organism GO:0032505 191 0.034
regulation of catalytic activity GO:0050790 307 0.034
positive regulation of cellular component biogenesis GO:0044089 45 0.033
regulation of cell cycle phase transition GO:1901987 70 0.033
nitrogen compound transport GO:0071705 212 0.033
macromolecule catabolic process GO:0009057 383 0.032
intracellular signal transduction GO:0035556 112 0.032
atp catabolic process GO:0006200 224 0.032
meiotic nuclear division GO:0007126 163 0.031
nucleoside phosphate catabolic process GO:1901292 331 0.030
cation transport GO:0006812 166 0.029
chemical homeostasis GO:0048878 137 0.029
regulation of signal transduction GO:0009966 114 0.029
negative regulation of gene expression GO:0010629 312 0.029
organonitrogen compound biosynthetic process GO:1901566 314 0.028
regulation of intracellular signal transduction GO:1902531 78 0.028
ribose phosphate metabolic process GO:0019693 384 0.028
regulation of hydrolase activity GO:0051336 133 0.028
cation homeostasis GO:0055080 105 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.027
negative regulation of catabolic process GO:0009895 43 0.026
positive regulation of phosphate metabolic process GO:0045937 147 0.026
cellular chemical homeostasis GO:0055082 123 0.026
regulation of nucleotide metabolic process GO:0006140 110 0.026
organic acid biosynthetic process GO:0016053 152 0.025
regulation of exit from mitosis GO:0007096 29 0.025
establishment or maintenance of cell polarity GO:0007163 96 0.025
organophosphate metabolic process GO:0019637 597 0.025
negative regulation of organelle organization GO:0010639 103 0.024
peptidyl amino acid modification GO:0018193 116 0.024
chromatin organization GO:0006325 242 0.024
intracellular protein transport GO:0006886 319 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.024
meiotic chromosome segregation GO:0045132 31 0.024
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.024
cell cycle g1 s phase transition GO:0044843 64 0.023
regulation of kinase activity GO:0043549 71 0.023
establishment of organelle localization GO:0051656 96 0.022
alpha amino acid metabolic process GO:1901605 124 0.022
regulation of meiosis i GO:0060631 14 0.022
negative regulation of molecular function GO:0044092 68 0.022
negative regulation of nuclear division GO:0051784 62 0.022
regulation of cell communication GO:0010646 124 0.022
carbohydrate metabolic process GO:0005975 252 0.022
lagging strand elongation GO:0006273 10 0.021
positive regulation of cell cycle GO:0045787 32 0.021
regulation of cellular catabolic process GO:0031329 195 0.021
purine containing compound catabolic process GO:0072523 332 0.021
cellular response to starvation GO:0009267 90 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.021
positive regulation of gene expression GO:0010628 321 0.021
negative regulation of dna replication GO:0008156 15 0.021
actin filament bundle organization GO:0061572 19 0.020
mitotic cell cycle checkpoint GO:0007093 56 0.020
positive regulation of catalytic activity GO:0043085 178 0.020
regulation of catabolic process GO:0009894 199 0.020
cellular homeostasis GO:0019725 138 0.020
nucleobase containing compound transport GO:0015931 124 0.020
dna templated transcription initiation GO:0006352 71 0.020
positive regulation of transcription dna templated GO:0045893 286 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
carboxylic acid biosynthetic process GO:0046394 152 0.019
regulation of response to stimulus GO:0048583 157 0.019
response to starvation GO:0042594 96 0.019
positive regulation of protein kinase activity GO:0045860 22 0.019
positive regulation of kinase activity GO:0033674 24 0.019
positive regulation of phosphorus metabolic process GO:0010562 147 0.018
positive regulation of protein modification process GO:0031401 49 0.018
apoptotic process GO:0006915 30 0.018
regulation of response to stress GO:0080134 57 0.018
modification dependent macromolecule catabolic process GO:0043632 203 0.018
negative regulation of dna dependent dna replication GO:2000104 8 0.018
negative regulation of phosphate metabolic process GO:0045936 49 0.018
ribonucleotide catabolic process GO:0009261 327 0.018
detection of stimulus GO:0051606 4 0.017
cell cycle g2 m phase transition GO:0044839 39 0.017
regulation of protein kinase activity GO:0045859 67 0.017
chromatin silencing GO:0006342 147 0.017
cellular response to abiotic stimulus GO:0071214 62 0.017
cellular cation homeostasis GO:0030003 100 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.017
response to abiotic stimulus GO:0009628 159 0.017
response to oxygen containing compound GO:1901700 61 0.016
positive regulation of intracellular protein transport GO:0090316 3 0.016
positive regulation of molecular function GO:0044093 185 0.016
mitotic dna damage checkpoint GO:0044773 11 0.016
anatomical structure development GO:0048856 160 0.016
transmembrane transport GO:0055085 349 0.016
cellular response to external stimulus GO:0071496 150 0.016
cellular ion homeostasis GO:0006873 112 0.015
response to heat GO:0009408 69 0.015
purine nucleoside triphosphate catabolic process GO:0009146 329 0.015
transition metal ion homeostasis GO:0055076 59 0.015
multi organism cellular process GO:0044764 120 0.015
macroautophagy GO:0016236 55 0.015
regulation of organelle organization GO:0033043 243 0.015
establishment of rna localization GO:0051236 92 0.014
retrograde transport endosome to golgi GO:0042147 33 0.014
meiosis i GO:0007127 92 0.014
positive regulation of programmed cell death GO:0043068 3 0.014
establishment of protein localization GO:0045184 367 0.014
purine ribonucleoside catabolic process GO:0046130 330 0.014
ion homeostasis GO:0050801 118 0.014
positive regulation of apoptotic process GO:0043065 3 0.014
cell death GO:0008219 30 0.014
ncrna processing GO:0034470 330 0.014
g2 dna damage checkpoint GO:0031572 1 0.014
regulation of g2 m transition of mitotic cell cycle GO:0010389 8 0.014
cellular response to nutrient levels GO:0031669 144 0.014
anion transport GO:0006820 145 0.014
response to inorganic substance GO:0010035 47 0.014
amine metabolic process GO:0009308 51 0.013
non recombinational repair GO:0000726 33 0.013
positive regulation of mitotic cell cycle GO:0045931 16 0.013
single organism cellular localization GO:1902580 375 0.013
death GO:0016265 30 0.013
protein ubiquitination GO:0016567 118 0.013
regulation of protein metabolic process GO:0051246 237 0.013
cell aging GO:0007569 70 0.013
positive regulation of cellular catabolic process GO:0031331 128 0.013
regulation of protein phosphorylation GO:0001932 75 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.013
negative regulation of mitosis GO:0045839 39 0.013
positive regulation of intracellular transport GO:0032388 4 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.012
response to extracellular stimulus GO:0009991 156 0.012
g2 m transition of mitotic cell cycle GO:0000086 38 0.012
positive regulation of cell death GO:0010942 3 0.012
conjugation with cellular fusion GO:0000747 106 0.012
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.012
aging GO:0007568 71 0.012
regulation of cellular amino acid metabolic process GO:0006521 16 0.012
negative regulation of phosphorus metabolic process GO:0010563 49 0.012
positive regulation of transferase activity GO:0051347 28 0.012
positive regulation of organelle organization GO:0010638 85 0.012
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.012
cellular ketone metabolic process GO:0042180 63 0.012
metal ion homeostasis GO:0055065 79 0.012
negative regulation of exit from mitosis GO:0001100 16 0.012
chromatin modification GO:0016568 200 0.012
programmed cell death GO:0012501 30 0.011
regulation of dna templated transcription initiation GO:2000142 19 0.011
cellular amine metabolic process GO:0044106 51 0.011
positive regulation of rna biosynthetic process GO:1902680 286 0.011
positive regulation of cellular biosynthetic process GO:0031328 336 0.011
regulation of protein modification process GO:0031399 110 0.011
regulation of chromatin silencing GO:0031935 39 0.011
cell division GO:0051301 205 0.011
cellular metal ion homeostasis GO:0006875 78 0.011
response to oxidative stress GO:0006979 99 0.011
replication fork protection GO:0048478 6 0.011
dna biosynthetic process GO:0071897 33 0.011
protein modification by small protein conjugation or removal GO:0070647 172 0.011
establishment of nucleus localization GO:0040023 22 0.011
cellular modified amino acid metabolic process GO:0006575 51 0.011
double strand break repair via nonhomologous end joining GO:0006303 27 0.011
negative regulation of cell communication GO:0010648 33 0.011
cellular response to extracellular stimulus GO:0031668 150 0.011
sister chromatid segregation GO:0000819 93 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
response to organic cyclic compound GO:0014070 1 0.011
response to nutrient levels GO:0031667 150 0.011
regulation of nuclear division GO:0051783 103 0.010
ras protein signal transduction GO:0007265 29 0.010
cellular protein catabolic process GO:0044257 213 0.010
nucleoside triphosphate metabolic process GO:0009141 364 0.010
gtp metabolic process GO:0046039 107 0.010
response to osmotic stress GO:0006970 83 0.010

MCM4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018