Danio rerio

0 known processes

mmp15a

matrix metallopeptidase 15a

mmp15a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.226
positive regulation of protein complex assembly GO:0031334 2 0.225
sensory perception of chemical stimulus GO:0007606 3 0.134
directional locomotion GO:0033058 1 0.105
regulation of cell differentiation GO:0045595 142 0.098
axon development GO:0061564 166 0.097
stem cell maintenance GO:0019827 4 0.093
maintenance of location GO:0051235 4 0.085
autophagy GO:0006914 4 0.071
lipid storage GO:0019915 1 0.070
fluid transport GO:0042044 17 0.068
embryonic organ morphogenesis GO:0048562 274 0.067
response to external stimulus GO:0009605 264 0.067
embryonic skeletal system development GO:0048706 97 0.064
neuron differentiation GO:0030182 353 0.063
sensory system development GO:0048880 76 0.063
mesenchyme development GO:0060485 127 0.062
cellular biosynthetic process GO:0044249 286 0.061
germ line stem cell maintenance GO:0030718 2 0.061
cellular response to nutrient levels GO:0031669 2 0.060
mechanosensory lateral line system development GO:0048881 49 0.060
tube morphogenesis GO:0035239 349 0.059
generation of neurons GO:0048699 385 0.059
regulation of epithelial cell proliferation GO:0050678 3 0.056
embryonic organ development GO:0048568 381 0.056
hormone biosynthetic process GO:0042446 3 0.054
positive regulation of myeloid cell differentiation GO:0045639 2 0.054
cellular component morphogenesis GO:0032989 336 0.051
neuron development GO:0048666 262 0.051
cell morphogenesis involved in differentiation GO:0000904 195 0.051
neural crest cell differentiation GO:0014033 72 0.051
actin cytoskeleton organization GO:0030036 63 0.050
cytoskeleton organization GO:0007010 96 0.050
oocyte maturation GO:0001556 4 0.049
androgen metabolic process GO:0008209 2 0.048
protein polymerization GO:0051258 4 0.048
actomyosin structure organization GO:0031032 53 0.046
regulation of multicellular organism growth GO:0040014 4 0.046
embryo development ending in birth or egg hatching GO:0009792 271 0.046
signal transduction in absence of ligand GO:0038034 1 0.046
single organism metabolic process GO:0044710 217 0.046
regulation of tube size GO:0035150 2 0.045
neuron projection development GO:0031175 180 0.045
positive regulation of protein polymerization GO:0032273 2 0.045
regulation of protein complex assembly GO:0043254 3 0.044
cellular response to starvation GO:0009267 1 0.044
gastrulation GO:0007369 208 0.042
posterior lateral line system development GO:0048915 46 0.041
regulation of multicellular organismal development GO:2000026 223 0.041
energy reserve metabolic process GO:0006112 2 0.041
regulation of protein polymerization GO:0032271 2 0.040
mesenchymal cell differentiation GO:0048762 87 0.040
embryonic skeletal system morphogenesis GO:0048704 93 0.040
convergent extension GO:0060026 118 0.040
single organism biosynthetic process GO:0044711 71 0.040
taxis GO:0042330 109 0.039
biosynthetic process GO:0009058 294 0.039
membrane fusion GO:0061025 2 0.038
regulation of neural precursor cell proliferation GO:2000177 3 0.038
positive regulation of epithelial cell differentiation GO:0030858 2 0.038
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.038
negative regulation of biological process GO:0048519 304 0.037
calcium ion transport into cytosol GO:0060402 3 0.037
regulation of blood vessel size GO:0050880 2 0.037
positive regulation of cellular component biogenesis GO:0044089 3 0.037
actin polymerization or depolymerization GO:0008154 2 0.037
cell projection organization GO:0030030 284 0.037
motor neuron axon guidance GO:0008045 23 0.036
stem cell division GO:0017145 1 0.036
convergent extension involved in gastrulation GO:0060027 71 0.036
cognition GO:0050890 1 0.036
extrinsic apoptotic signaling pathway GO:0097191 3 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.035
single organism membrane fusion GO:0044801 2 0.035
response to stress GO:0006950 263 0.035
locomotion GO:0040011 313 0.034
response to glucocorticoid GO:0051384 1 0.034
axonogenesis GO:0007409 152 0.034
calcium ion import GO:0070509 4 0.034
lateral line system development GO:0048925 76 0.033
regulation of biological quality GO:0065008 263 0.033
phagocytosis GO:0006909 3 0.033
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
chordate embryonic development GO:0043009 271 0.032
macroautophagy GO:0016236 1 0.032
digestive system development GO:0055123 289 0.032
cyclic purine nucleotide metabolic process GO:0052652 18 0.032
glucose homeostasis GO:0042593 1 0.032
embryonic heart tube morphogenesis GO:0003143 108 0.032
muscle structure development GO:0061061 196 0.031
embryonic cranial skeleton morphogenesis GO:0048701 90 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
regulation of synaptic plasticity GO:0048167 1 0.031
stem cell development GO:0048864 82 0.031
cell part morphogenesis GO:0032990 246 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
organonitrogen compound metabolic process GO:1901564 74 0.030
ovulation cycle GO:0042698 2 0.030
estrogen metabolic process GO:0008210 2 0.030
organic substance biosynthetic process GO:1901576 289 0.030
negative regulation of cellular process GO:0048523 283 0.030
regulation of autophagy GO:0010506 3 0.030
female gonad development GO:0008585 4 0.030
regulation of carbohydrate metabolic process GO:0006109 4 0.030
skeletal system development GO:0001501 181 0.029
cellular response to external stimulus GO:0071496 2 0.029
aging GO:0007568 2 0.029
stem cell differentiation GO:0048863 117 0.028
cytosolic calcium ion transport GO:0060401 3 0.028
regulation of blood pressure GO:0008217 1 0.028
stem cell proliferation GO:0072089 4 0.028
positive regulation of stress activated mapk cascade GO:0032874 3 0.028
response to abiotic stimulus GO:0009628 122 0.028
carboxylic acid metabolic process GO:0019752 22 0.027
regulation of dna templated transcription in response to stress GO:0043620 0 0.027
glutamate receptor signaling pathway GO:0007215 1 0.027
cell projection morphogenesis GO:0048858 244 0.026
cell substrate adhesion GO:0031589 4 0.026
negative regulation of reproductive process GO:2000242 3 0.026
membrane lipid biosynthetic process GO:0046467 2 0.026
cellular carbohydrate metabolic process GO:0044262 4 0.026
negative regulation of synapse assembly GO:0051964 2 0.026
positive regulation of cytoskeleton organization GO:0051495 3 0.026
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
neuron neuron synaptic transmission GO:0007270 1 0.025
female sex differentiation GO:0046660 4 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
signal transduction GO:0007165 455 0.025
single organism organelle organization GO:1902589 199 0.025
response to corticosteroid GO:0031960 1 0.025
neuron projection morphogenesis GO:0048812 161 0.025
heterocycle biosynthetic process GO:0018130 215 0.024
striated muscle cell development GO:0055002 108 0.024
organelle organization GO:0006996 227 0.024
taurine metabolic process GO:0019530 1 0.024
small molecule metabolic process GO:0044281 77 0.024
response to glucose GO:0009749 3 0.024
regulation of metabolic process GO:0019222 359 0.023
sphingolipid biosynthetic process GO:0030148 2 0.023
myofibril assembly GO:0030239 48 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
regulation of cell activation GO:0050865 1 0.023
regulation of oocyte development GO:0060281 3 0.023
positive regulation of catabolic process GO:0009896 4 0.023
cellular amino acid metabolic process GO:0006520 7 0.022
system process GO:0003008 185 0.022
development of primary female sexual characteristics GO:0046545 4 0.022
digestive tract development GO:0048565 265 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
multicellular organism growth GO:0035264 4 0.022
nucleic acid metabolic process GO:0090304 244 0.022
neuroblast proliferation GO:0007405 2 0.022
regulation of reproductive process GO:2000241 4 0.022
syncytium formation GO:0006949 12 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
eye development GO:0001654 277 0.022
negative regulation of catabolic process GO:0009895 3 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
regulation of synapse assembly GO:0051963 3 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.021
positive regulation of endothelial cell proliferation GO:0001938 1 0.021
cellular ketone metabolic process GO:0042180 11 0.021
mesenchymal cell development GO:0014031 78 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
adherens junction organization GO:0034332 4 0.021
striated muscle cell differentiation GO:0051146 129 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
response to monosaccharide GO:0034284 3 0.020
regulation of cell substrate adhesion GO:0010810 1 0.020
cell cell adhesion involved in gastrulation GO:0070586 4 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
digestive tract morphogenesis GO:0048546 231 0.020
cellular component biogenesis GO:0044085 178 0.020
negative regulation of cell communication GO:0010648 96 0.020
organelle fusion GO:0048284 3 0.020
response to carbohydrate GO:0009743 3 0.019
regulation of cytokine production GO:0001817 3 0.019
oxidation reduction process GO:0055114 41 0.019
central nervous system development GO:0007417 387 0.019
gene expression GO:0010467 252 0.019
regulation of erythrocyte differentiation GO:0045646 2 0.019
cytokinesis GO:0000910 3 0.019
cellular hormone metabolic process GO:0034754 19 0.019
regulation of developmental process GO:0050793 247 0.019
neural crest cell development GO:0014032 62 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
locomotor rhythm GO:0045475 3 0.019
cell morphogenesis GO:0000902 289 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.018
protein complex disassembly GO:0043241 1 0.018
golgi vesicle transport GO:0048193 3 0.018
tube closure GO:0060606 1 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
multicellular organismal response to stress GO:0033555 2 0.018
positive regulation of transport GO:0051050 2 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
carbohydrate biosynthetic process GO:0016051 1 0.018
phosphatidylinositol mediated signaling GO:0048015 2 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
negative regulation of signaling GO:0023057 96 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
regulation of biomineral tissue development GO:0070167 2 0.017
syncytium formation by plasma membrane fusion GO:0000768 12 0.017
gtp catabolic process GO:0006184 2 0.017
regulation of dna replication GO:0006275 3 0.017
response to chemical GO:0042221 320 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
response to osmotic stress GO:0006970 11 0.017
b cell activation GO:0042113 2 0.016
actin filament polymerization GO:0030041 2 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
lateral inhibition GO:0046331 1 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.016
protein localization to nucleus GO:0034504 3 0.016
rna biosynthetic process GO:0032774 181 0.016
cortical cytoskeleton organization GO:0030865 1 0.016
cation homeostasis GO:0055080 33 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
ribonucleotide biosynthetic process GO:0009260 20 0.016
nucleotide biosynthetic process GO:0009165 21 0.016
response to oxygen containing compound GO:1901700 55 0.016
cell migration GO:0016477 237 0.016
macromolecular complex disassembly GO:0032984 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
anterior lateral line system development GO:0048898 9 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
positive regulation of cellular process GO:0048522 201 0.015
regulation of bone mineralization GO:0030500 2 0.015
skeletal system morphogenesis GO:0048705 102 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
oxoacid metabolic process GO:0043436 31 0.015
primary neural tube formation GO:0014020 1 0.015
membrane invagination GO:0010324 1 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
nucleic acid templated transcription GO:0097659 181 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
chemotaxis GO:0006935 104 0.015
cellular amine metabolic process GO:0044106 2 0.015
immune system development GO:0002520 191 0.015
cellular component movement GO:0006928 335 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
response to organic cyclic compound GO:0014070 51 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
regulation of protein transport GO:0051223 3 0.014
cell death GO:0008219 121 0.014
regulation of response to stimulus GO:0048583 269 0.014
cellular component assembly GO:0022607 170 0.014
cellular response to organic substance GO:0071310 105 0.014
amine metabolic process GO:0009308 2 0.014
meiotic nuclear division GO:0007126 4 0.014
carbohydrate homeostasis GO:0033500 1 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
protein localization to plasma membrane GO:0072659 1 0.014
positive regulation of cell cycle GO:0045787 3 0.014
lipid metabolic process GO:0006629 52 0.014
determination of bilateral symmetry GO:0009855 204 0.014
response to other organism GO:0051707 97 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
dorsal convergence GO:0060030 14 0.014
smooth muscle contraction GO:0006939 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
b cell differentiation GO:0030183 1 0.013
positive regulation of cell substrate adhesion GO:0010811 1 0.013
hemopoiesis GO:0030097 183 0.013
heart development GO:0007507 313 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
transcription dna templated GO:0006351 181 0.013
multi organism process GO:0051704 134 0.013
camp biosynthetic process GO:0006171 11 0.013
lateral line development GO:0048882 66 0.013
spermatid development GO:0007286 2 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
er to golgi vesicle mediated transport GO:0006888 1 0.013
organic acid metabolic process GO:0006082 31 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
regulation of signaling GO:0023051 235 0.013
cellular response to reactive oxygen species GO:0034614 2 0.013
programmed cell death GO:0012501 119 0.013
neural crest formation GO:0014029 14 0.013
positive regulation of immune effector process GO:0002699 3 0.013
protein metabolic process GO:0019538 183 0.013
somatic muscle development GO:0007525 4 0.013
receptor internalization GO:0031623 2 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
response to organic substance GO:0010033 153 0.013
developmental growth GO:0048589 166 0.013
organism emergence from protective structure GO:0071684 4 0.013
behavior GO:0007610 74 0.012
gtp metabolic process GO:0046039 4 0.012
anterior posterior pattern specification GO:0009952 152 0.012
response to hexose GO:0009746 3 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
negative regulation of autophagy GO:0010507 1 0.012
mononuclear cell proliferation GO:0032943 1 0.012
heart process GO:0003015 71 0.012
specification of symmetry GO:0009799 204 0.012
regulation of protein catabolic process GO:0042176 1 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
methylation GO:0032259 22 0.012
olfactory lobe development GO:0021988 4 0.012
regulation of endothelial cell proliferation GO:0001936 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
myeloid cell differentiation GO:0030099 86 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
regulation of cell communication GO:0010646 232 0.012
chemical homeostasis GO:0048878 49 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
response to mechanical stimulus GO:0009612 24 0.012
regulation of anatomical structure size GO:0090066 33 0.012
cellular response to oxygen levels GO:0071453 1 0.012
response to external biotic stimulus GO:0043207 97 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
spermatid differentiation GO:0048515 2 0.012
protein homooligomerization GO:0051260 3 0.012
positive regulation of histone modification GO:0031058 1 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
muscle cell development GO:0055001 115 0.012
regulation of apoptotic process GO:0042981 98 0.012
response to nutrient GO:0007584 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of activin receptor signaling pathway GO:0032925 5 0.011
wnt signaling pathway GO:0016055 80 0.011
somitogenesis GO:0001756 87 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.011
regulation of biosynthetic process GO:0009889 250 0.011
cellular component disassembly GO:0022411 1 0.011
regionalization GO:0003002 274 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
hormone secretion GO:0046879 2 0.011
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.011
positive regulation of glucose import GO:0046326 1 0.011
axon midline choice point recognition GO:0016199 4 0.011
organophosphate biosynthetic process GO:0090407 23 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
compound eye development GO:0048749 2 0.011
organelle assembly GO:0070925 110 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
regulation of localization GO:0032879 104 0.011
exocytosis GO:0006887 1 0.011
regulation of cell maturation GO:1903429 1 0.011
protein complex biogenesis GO:0070271 30 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
atp catabolic process GO:0006200 4 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
leukocyte proliferation GO:0070661 1 0.011
cellular ion homeostasis GO:0006873 17 0.011
androgen biosynthetic process GO:0006702 1 0.011
response to ketone GO:1901654 1 0.011
actin filament based process GO:0030029 64 0.011
regulation of gene expression GO:0010468 265 0.010
post golgi vesicle mediated transport GO:0006892 1 0.010
positive regulation of biological process GO:0048518 253 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
nuclear import GO:0051170 3 0.010
regulation of locomotion GO:0040012 55 0.010
cell motility GO:0048870 244 0.010
protein dephosphorylation GO:0006470 3 0.010
growth GO:0040007 174 0.010
determination of left right symmetry GO:0007368 179 0.010
atrial cardiac myofibril assembly GO:0055004 2 0.010
lipid biosynthetic process GO:0008610 22 0.010
regulation of binding GO:0051098 3 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
homeostatic process GO:0042592 142 0.010
apoptotic process GO:0006915 116 0.010
cyclic nucleotide metabolic process GO:0009187 18 0.010
negative regulation of metabolic process GO:0009892 86 0.010
negative regulation of kinase activity GO:0033673 4 0.010
myoblast fusion GO:0007520 10 0.010
cytoplasm organization GO:0007028 4 0.010
skeletal muscle tissue development GO:0007519 67 0.010

mmp15a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
immune system disease DOID:2914 0 0.014
nervous system disease DOID:863 0 0.011