Danio rerio

27 known processes

rer1

RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)

(Aliases: zgc:65968,MGC65968)

rer1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of an epithelium GO:0002009 333 0.217
cation transport GO:0006812 81 0.203
cell projection organization GO:0030030 284 0.173
regulation of macromolecule metabolic process GO:0060255 317 0.170
single organism transport GO:0044765 206 0.160
establishment of localization GO:0051234 244 0.148
golgi vesicle transport GO:0048193 3 0.117
regulation of metal ion transport GO:0010959 4 0.111
organelle organization GO:0006996 227 0.107
localization of cell GO:0051674 244 0.106
positive regulation of transport GO:0051050 2 0.103
ion transport GO:0006811 114 0.102
embryo development ending in birth or egg hatching GO:0009792 271 0.093
regulation of cell communication GO:0010646 232 0.087
tube morphogenesis GO:0035239 349 0.085
larval development GO:0002164 2 0.083
cellular component movement GO:0006928 335 0.075
regulation of multicellular organismal process GO:0051239 277 0.075
sensory organ development GO:0007423 393 0.073
regulation of biological quality GO:0065008 263 0.073
establishment of localization in cell GO:0051649 77 0.071
immune system process GO:0002376 241 0.070
organic substance biosynthetic process GO:1901576 289 0.070
growth GO:0040007 174 0.067
guanosine containing compound catabolic process GO:1901069 2 0.065
extrinsic apoptotic signaling pathway GO:0097191 3 0.062
transport GO:0006810 220 0.060
cellular amine metabolic process GO:0044106 2 0.060
regulation of multicellular organismal development GO:2000026 223 0.060
locomotion GO:0040011 313 0.059
cilium organization GO:0044782 71 0.058
modification dependent macromolecule catabolic process GO:0043632 3 0.058
cation transmembrane transport GO:0098655 65 0.056
inorganic cation transmembrane transport GO:0098662 50 0.055
positive regulation of macromolecule metabolic process GO:0010604 93 0.054
regulation of erk1 and erk2 cascade GO:0070372 4 0.053
negative regulation of catabolic process GO:0009895 3 0.052
positive regulation of metabolic process GO:0009893 108 0.051
axonemal dynein complex assembly GO:0070286 5 0.051
multi organism process GO:0051704 134 0.051
embryonic cranial skeleton morphogenesis GO:0048701 90 0.049
determination of left right symmetry GO:0007368 179 0.049
single organism localization GO:1902578 225 0.048
digestive tract development GO:0048565 265 0.048
cellular component morphogenesis GO:0032989 336 0.047
localization within membrane GO:0051668 1 0.047
response to stress GO:0006950 263 0.047
amine metabolic process GO:0009308 2 0.046
lipid storage GO:0019915 1 0.046
regulation of signal transduction GO:0009966 225 0.046
cellular protein catabolic process GO:0044257 4 0.046
negative regulation of cytoplasmic transport GO:1903650 2 0.046
modification dependent protein catabolic process GO:0019941 3 0.045
regulation of cellular metabolic process GO:0031323 320 0.045
maintenance of location GO:0051235 4 0.045
positive regulation of biological process GO:0048518 253 0.044
multicellular organism growth GO:0035264 4 0.044
digestive system development GO:0055123 289 0.043
cilium assembly GO:0042384 58 0.042
regulation of protein ubiquitination GO:0031396 3 0.042
positive regulation of developmental process GO:0051094 50 0.042
cell death GO:0008219 121 0.041
protein polyubiquitination GO:0000209 4 0.041
response to topologically incorrect protein GO:0035966 2 0.040
positive regulation of apoptotic signaling pathway GO:2001235 1 0.040
positive regulation of signaling GO:0023056 56 0.040
positive regulation of cellular process GO:0048522 201 0.040
phosphate containing compound metabolic process GO:0006796 108 0.039
cellular localization GO:0051641 97 0.039
neuron development GO:0048666 262 0.038
regulation of developmental process GO:0050793 247 0.038
negative regulation of cellular process GO:0048523 283 0.037
apoptotic process GO:0006915 116 0.036
cellular response to chemical stimulus GO:0070887 157 0.036
gtp metabolic process GO:0046039 4 0.036
cellular amide metabolic process GO:0043603 4 0.036
organic substance transport GO:0071702 58 0.036
establishment of organelle localization GO:0051656 45 0.034
regulation of tube size GO:0035150 2 0.034
phagocytosis GO:0006909 3 0.034
regulation of cytoplasmic transport GO:1903649 4 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
embryonic skeletal system morphogenesis GO:0048704 93 0.032
convergent extension GO:0060026 118 0.032
er nucleus signaling pathway GO:0006984 2 0.032
photoreceptor cell outer segment organization GO:0035845 9 0.032
actin polymerization or depolymerization GO:0008154 2 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.032
heart morphogenesis GO:0003007 156 0.031
head development GO:0060322 303 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
regulation of purine nucleotide catabolic process GO:0033121 2 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
regulation of signaling GO:0023051 235 0.031
protein targeting to membrane GO:0006612 1 0.030
cilium morphogenesis GO:0060271 85 0.030
cellular response to unfolded protein GO:0034620 2 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
autophagy GO:0006914 4 0.030
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.030
cellular biosynthetic process GO:0044249 286 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
ion transmembrane transport GO:0034220 91 0.029
determination of bilateral symmetry GO:0009855 204 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.028
cellular ketone metabolic process GO:0042180 11 0.028
generation of neurons GO:0048699 385 0.028
angiogenesis GO:0001525 158 0.028
protein metabolic process GO:0019538 183 0.028
organelle localization GO:0051640 49 0.028
negative regulation of metabolic process GO:0009892 86 0.027
macromolecule localization GO:0033036 54 0.027
somitogenesis GO:0001756 87 0.027
cell migration GO:0016477 237 0.027
embryonic organ development GO:0048568 381 0.027
regulation of nucleotide catabolic process GO:0030811 2 0.026
response to unfolded protein GO:0006986 2 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
cell motility GO:0048870 244 0.026
regulation of localization GO:0032879 104 0.026
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.025
regulation of transmembrane transporter activity GO:0022898 2 0.025
metal ion transport GO:0030001 58 0.025
neuron differentiation GO:0030182 353 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
signal transduction GO:0007165 455 0.025
anterior posterior pattern specification GO:0009952 152 0.024
negative regulation of protein transport GO:0051224 3 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
chordate embryonic development GO:0043009 271 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
positive regulation of map kinase activity GO:0043406 3 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of primary metabolic process GO:0080090 311 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
gtp catabolic process GO:0006184 2 0.023
death GO:0016265 121 0.023
inorganic ion transmembrane transport GO:0098660 57 0.023
er to golgi vesicle mediated transport GO:0006888 1 0.023
small molecule metabolic process GO:0044281 77 0.023
developmental programmed cell death GO:0010623 4 0.023
calcium mediated signaling GO:0019722 2 0.023
gastrulation GO:0007369 208 0.023
ameboidal type cell migration GO:0001667 143 0.022
cellular response to nutrient levels GO:0031669 2 0.022
reproduction GO:0000003 40 0.022
protein import GO:0017038 3 0.022
protein import into nucleus GO:0006606 3 0.022
protein localization to nucleus GO:0034504 3 0.022
divalent metal ion transport GO:0070838 20 0.022
neuromast development GO:0048884 46 0.021
photoreceptor cell development GO:0042461 40 0.021
negative regulation of biological process GO:0048519 304 0.021
system process GO:0003008 185 0.021
response to drug GO:0042493 3 0.021
organic acid metabolic process GO:0006082 31 0.021
regulation of blood vessel size GO:0050880 2 0.021
regulation of transporter activity GO:0032409 2 0.021
embryonic limb morphogenesis GO:0030326 2 0.021
single organism membrane fusion GO:0044801 2 0.021
stem cell proliferation GO:0072089 4 0.021
axon ensheathment in central nervous system GO:0032291 2 0.021
programmed cell death GO:0012501 119 0.020
specification of symmetry GO:0009799 204 0.020
tube closure GO:0060606 1 0.020
regulation of hormone secretion GO:0046883 2 0.020
regulation of cytokine production GO:0001817 3 0.020
central nervous system development GO:0007417 387 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
regulation of cell motility GO:2000145 46 0.019
membrane repolarization GO:0086009 2 0.019
cellular response to topologically incorrect protein GO:0035967 2 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
regulation of ion transmembrane transport GO:0034765 18 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
transmembrane transport GO:0055085 120 0.019
tyrosine phosphorylation of stat protein GO:0007260 1 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
gene expression GO:0010467 252 0.019
regulation of response to stimulus GO:0048583 269 0.019
positive regulation of myeloid cell differentiation GO:0045639 2 0.018
blood circulation GO:0008015 87 0.018
biosynthetic process GO:0009058 294 0.018
lateral line system development GO:0048925 76 0.018
cell part morphogenesis GO:0032990 246 0.018
translational initiation GO:0006413 3 0.018
blood vessel development GO:0001568 246 0.018
protein k48 linked ubiquitination GO:0070936 1 0.018
neuroblast proliferation GO:0007405 2 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
positive regulation of multicellular organismal process GO:0051240 52 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
negative regulation of mrna metabolic process GO:1903312 3 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
spermatid differentiation GO:0048515 2 0.017
ion homeostasis GO:0050801 41 0.017
regulation of autophagy GO:0010506 3 0.017
digestive tract morphogenesis GO:0048546 231 0.017
regulation of reproductive process GO:2000241 4 0.017
regulation of protein transport GO:0051223 3 0.017
negative regulation of autophagy GO:0010507 1 0.016
axon development GO:0061564 166 0.016
positive regulation of notch signaling pathway GO:0045747 3 0.016
hormone transport GO:0009914 2 0.016
regulation of striated muscle contraction GO:0006942 2 0.016
regulation of gene expression GO:0010468 265 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of cellular component movement GO:0051270 55 0.016
macroautophagy GO:0016236 1 0.016
single organism metabolic process GO:0044710 217 0.016
carbohydrate homeostasis GO:0033500 1 0.016
single organism biosynthetic process GO:0044711 71 0.016
regulation of cell activation GO:0050865 1 0.016
wnt signaling pathway GO:0016055 80 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
cortical cytoskeleton organization GO:0030865 1 0.015
regulation of metabolic process GO:0019222 359 0.015
heart development GO:0007507 313 0.015
apoptotic process involved in development GO:1902742 2 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.015
beta amyloid metabolic process GO:0050435 1 0.015
primary neural tube formation GO:0014020 1 0.015
leukocyte proliferation GO:0070661 1 0.015
energy reserve metabolic process GO:0006112 2 0.015
regulation of phosphorus metabolic process GO:0051174 43 0.015
atp catabolic process GO:0006200 4 0.015
regulation of ion transport GO:0043269 22 0.015
carboxylic acid metabolic process GO:0019752 22 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
regulation of membrane repolarization GO:0060306 1 0.014
cellular response to starvation GO:0009267 1 0.014
cilium movement involved in cell motility GO:0060294 3 0.014
regulation of sodium ion transport GO:0002028 2 0.014
regulation of muscle contraction GO:0006937 3 0.014
pigmentation GO:0043473 85 0.014
regulation of protein metabolic process GO:0051246 56 0.014
cell projection morphogenesis GO:0048858 244 0.014
oxoacid metabolic process GO:0043436 31 0.014
golgi organization GO:0007030 1 0.014
developmental growth GO:0048589 166 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
endoplasmic reticulum unfolded protein response GO:0030968 2 0.014
homeostatic process GO:0042592 142 0.014
neuron projection development GO:0031175 180 0.014
cell proliferation GO:0008283 80 0.014
somite development GO:0061053 96 0.013
protein secretion GO:0009306 1 0.013
cell morphogenesis GO:0000902 289 0.013
positive regulation of molecular function GO:0044093 33 0.013
regulation of molecular function GO:0065009 70 0.013
negative regulation of cytokine production GO:0001818 1 0.013
peptide transport GO:0015833 1 0.013
aging GO:0007568 2 0.013
stem cell division GO:0017145 1 0.013
microtubule cytoskeleton organization GO:0000226 33 0.013
regulation of binding GO:0051098 3 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.013
single organism cellular localization GO:1902580 46 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
positive regulation of cell cycle GO:0045787 3 0.013
regulation of epidermis development GO:0045682 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
phosphorus metabolic process GO:0006793 109 0.013
regulation of jak stat cascade GO:0046425 3 0.013
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.013
response to endoplasmic reticulum stress GO:0034976 6 0.013
vasculature development GO:0001944 278 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.012
chemotaxis GO:0006935 104 0.012
positive regulation of epithelial cell differentiation GO:0030858 2 0.012
regulation of calcium ion transport GO:0051924 2 0.012
entrainment of circadian clock GO:0009649 2 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
recombinational repair GO:0000725 1 0.012
embryonic heart tube development GO:0035050 133 0.012
striated muscle cell differentiation GO:0051146 129 0.012
circulatory system process GO:0003013 87 0.012
cellular response to external stimulus GO:0071496 2 0.012
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.012
apoptotic process involved in morphogenesis GO:0060561 2 0.012
mononuclear cell proliferation GO:0032943 1 0.012
intracellular signal transduction GO:0035556 85 0.012
positive regulation of signal transduction GO:0009967 56 0.012
vacuole organization GO:0007033 9 0.012
adult behavior GO:0030534 2 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
microtubule organizing center organization GO:0031023 1 0.012
peptide metabolic process GO:0006518 1 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
negative regulation of signal transduction GO:0009968 94 0.012
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.012
cellular response to radiation GO:0071478 4 0.012
nucleic acid templated transcription GO:0097659 181 0.012
meiotic cell cycle process GO:1903046 3 0.012
regulation of gtpase activity GO:0043087 2 0.011
stem cell fate commitment GO:0048865 1 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of catalytic activity GO:0050790 55 0.011
positive regulation of catabolic process GO:0009896 4 0.011
embryonic skeletal system development GO:0048706 97 0.011
heterocycle metabolic process GO:0046483 290 0.011
establishment of endothelial barrier GO:0061028 3 0.011
organophosphate biosynthetic process GO:0090407 23 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
neural tube patterning GO:0021532 33 0.011
reproductive process GO:0022414 40 0.011
sodium ion transport GO:0006814 24 0.011
regulation of cell development GO:0060284 100 0.011
regulation of protein binding GO:0043393 3 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
interspecies interaction between organisms GO:0044419 4 0.011
positive regulation of cell communication GO:0010647 56 0.011
positive regulation of gliogenesis GO:0014015 2 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
chemical homeostasis GO:0048878 49 0.011
mitochondrion organization GO:0007005 4 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
protein targeting to nucleus GO:0044744 3 0.011
regulation of cellular component organization GO:0051128 86 0.011
cellular pigmentation GO:0033059 30 0.011
negative regulation of mrna processing GO:0050686 1 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
response to uv GO:0009411 3 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
actin filament based movement GO:0030048 1 0.010
muscle cell migration GO:0014812 4 0.010
cell adhesion GO:0007155 40 0.010
epidermis morphogenesis GO:0048730 4 0.010

rer1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
auditory system disease DOID:2742 0 0.011
nonsyndromic deafness DOID:0050563 0 0.011
sensory system disease DOID:0050155 0 0.011
nervous system disease DOID:863 0 0.011