Danio rerio

57 known processes

sox9a

SRY-box containing gene 9a

(Aliases: zgc:111921,jef,wu:fj17b12)

sox9a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 181 1.000
embryonic organ morphogenesis GO:0048562 274 1.000
sensory organ morphogenesis GO:0090596 200 1.000
chordate embryonic development GO:0043009 271 0.999
embryonic viscerocranium morphogenesis GO:0048703 52 0.999
embryonic skeletal system morphogenesis GO:0048704 93 0.999
sensory organ development GO:0007423 393 0.998
skeletal system morphogenesis GO:0048705 102 0.997
Human Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.996
embryonic organ development GO:0048568 381 0.996
inner ear development GO:0048839 126 0.995
cartilage development GO:0051216 96 0.995
regionalization GO:0003002 274 0.992
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.992
Mouse
heart morphogenesis GO:0003007 156 0.991
Zebrafish Mouse
connective tissue development GO:0061448 99 0.991
embryonic skeletal system development GO:0048706 97 0.990
organic substance biosynthetic process GO:1901576 289 0.988
Human Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.987
Human Zebrafish Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.986
Mouse
multicellular organism reproduction GO:0032504 35 0.985
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.983
Mouse
positive regulation of biological process GO:0048518 253 0.981
Human Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.980
Human Zebrafish Mouse
appendage morphogenesis GO:0035107 56 0.979
embryonic cranial skeleton morphogenesis GO:0048701 90 0.978
biosynthetic process GO:0009058 294 0.973
Human Zebrafish Mouse
cartilage morphogenesis GO:0060536 13 0.972
inner ear receptor cell differentiation GO:0060113 29 0.968
Zebrafish
myotube cell development GO:0014904 35 0.967
Mouse
endochondral bone morphogenesis GO:0060350 8 0.967
Human Mouse
rna biosynthetic process GO:0032774 181 0.967
Human Zebrafish Mouse
retina development in camera type eye GO:0060041 146 0.955
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.948
Human Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.942
Human Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.941
Human Zebrafish Mouse
digestive tract development GO:0048565 265 0.939
Zebrafish
regulation of chondrocyte differentiation GO:0032330 1 0.938
Human Mouse
blood vessel development GO:0001568 246 0.936
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.933
Mouse
regulation of multicellular organismal process GO:0051239 277 0.927
Human Zebrafish Mouse
signal transduction GO:0007165 455 0.926
Human Mouse
odontogenesis GO:0042476 9 0.923
embryonic limb morphogenesis GO:0030326 2 0.922
regulation of epithelial cell proliferation GO:0050678 3 0.919
Human Mouse
embryonic heart tube development GO:0035050 133 0.916
Zebrafish
neuron development GO:0048666 262 0.911
Zebrafish
determination of left right symmetry GO:0007368 179 0.902
Zebrafish
cellular response to lipid GO:0071396 39 0.900
Human Mouse
periodic partitioning GO:0007365 1 0.897
cellular biosynthetic process GO:0044249 286 0.894
Human Zebrafish Mouse
stem cell differentiation GO:0048863 117 0.892
Human Mouse
eye morphogenesis GO:0048592 144 0.892
Zebrafish Mouse
gene expression GO:0010467 252 0.884
Human Zebrafish Mouse
response to chemical GO:0042221 320 0.883
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.881
Human Zebrafish Mouse
neuron differentiation GO:0030182 353 0.861
Zebrafish Mouse
chemotaxis GO:0006935 104 0.855
cellular response to growth factor stimulus GO:0071363 39 0.853
Human Mouse
positive regulation of muscle organ development GO:0048636 1 0.848
positive regulation of cellular process GO:0048522 201 0.842
Human Zebrafish Mouse
locomotion GO:0040011 313 0.842
Human Zebrafish Mouse
kidney vasculature development GO:0061440 2 0.839
ear development GO:0043583 127 0.834
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.831
Human
morphogenesis of an epithelium GO:0002009 333 0.828
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.827
multicellular organismal reproductive process GO:0048609 35 0.810
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.803
cellular response to endogenous stimulus GO:0071495 68 0.799
Human Mouse
hindbrain development GO:0030902 91 0.792
larval development GO:0002164 2 0.783
fin morphogenesis GO:0033334 53 0.773
preganglionic parasympathetic nervous system development GO:0021783 6 0.770
regulation of skeletal muscle tissue development GO:0048641 4 0.764
Mouse
pectoral fin development GO:0033339 50 0.752
organic cyclic compound biosynthetic process GO:1901362 223 0.744
Human Zebrafish Mouse
ossification GO:0001503 23 0.741
Mouse
mesoderm development GO:0007498 88 0.740
Zebrafish
response to corticosteroid GO:0031960 1 0.737
regulation of biological quality GO:0065008 263 0.735
Mouse
otic vesicle development GO:0071599 42 0.722
hair cell differentiation GO:0035315 32 0.720
glomerulus vasculature development GO:0072012 2 0.720
osteoblast differentiation GO:0001649 5 0.718
response to external stimulus GO:0009605 264 0.715
Mouse
dorsal ventral neural tube patterning GO:0021904 1 0.710
cellular response to organic substance GO:0071310 105 0.710
Human Mouse
astrocyte differentiation GO:0048708 1 0.694
muscle fiber development GO:0048747 52 0.693
Mouse
mechanoreceptor differentiation GO:0042490 37 0.691
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.684
Human Zebrafish Mouse
bmp signaling pathway GO:0030509 52 0.683
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.681
Human Zebrafish Mouse
appendage development GO:0048736 80 0.671
positive regulation of cellular component movement GO:0051272 11 0.671
Human Mouse
response to growth factor GO:0070848 39 0.666
Human Mouse
photoreceptor cell differentiation GO:0046530 55 0.656
Mouse
female sex differentiation GO:0046660 4 0.653
regulation of rna metabolic process GO:0051252 224 0.645
Human Zebrafish Mouse
reproductive process GO:0022414 40 0.645
Human Mouse
digestive system development GO:0055123 289 0.641
Zebrafish
vasculature development GO:0001944 278 0.640
Zebrafish
regulation of gene expression GO:0010468 265 0.633
Human Zebrafish Mouse
camera type eye photoreceptor cell differentiation GO:0060219 19 0.633
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.632
Human Zebrafish Mouse
somitogenesis GO:0001756 87 0.631
heart development GO:0007507 313 0.631
Zebrafish Mouse
endothelial cell differentiation GO:0045446 20 0.626
Zebrafish
regulation of signal transduction GO:0009966 225 0.625
Mouse
embryonic appendage morphogenesis GO:0035113 30 0.614
organic cyclic compound metabolic process GO:1901360 301 0.613
Human Zebrafish Mouse
neural tube formation GO:0001841 16 0.605
negative regulation of cell communication GO:0010648 96 0.604
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.598
Human Zebrafish Mouse
ectodermal placode development GO:0071696 37 0.597
pigment cell differentiation GO:0050931 38 0.591
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.589
Mouse
positive regulation of cell communication GO:0010647 56 0.588
Mouse
otic vesicle formation GO:0030916 27 0.586
regulation of reproductive process GO:2000241 4 0.584
Human
developmental process involved in reproduction GO:0003006 27 0.582
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.582
negative regulation of biological process GO:0048519 304 0.576
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.571
Human Zebrafish Mouse
neural crest cell development GO:0014032 62 0.561
Mouse
muscle cell development GO:0055001 115 0.559
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.554
Human Zebrafish Mouse
pronephros development GO:0048793 69 0.543
positive regulation of muscle cell differentiation GO:0051149 1 0.540
epithelial cell development GO:0002064 42 0.539
Zebrafish Mouse
gland development GO:0048732 143 0.538
Human Zebrafish Mouse
multicellular organism growth GO:0035264 4 0.538
camera type eye development GO:0043010 222 0.537
Zebrafish Mouse
tissue migration GO:0090130 37 0.531
Human Mouse
regulation of signaling GO:0023051 235 0.529
Mouse
forebrain neuron development GO:0021884 7 0.528
retina layer formation GO:0010842 24 0.527
response to glucocorticoid GO:0051384 1 0.527
cell projection organization GO:0030030 284 0.527
meiotic nuclear division GO:0007126 4 0.524
cellular nitrogen compound metabolic process GO:0034641 290 0.521
Human Zebrafish Mouse
cellular response to chemical stimulus GO:0070887 157 0.512
Human Mouse
myotube differentiation GO:0014902 45 0.508
Mouse
developmental pigmentation GO:0048066 48 0.508
Zebrafish
neural retina development GO:0003407 49 0.508
Mouse
patterning of blood vessels GO:0001569 15 0.504
angiogenesis GO:0001525 158 0.501
central nervous system development GO:0007417 387 0.500
inner ear morphogenesis GO:0042472 63 0.496
cellular component movement GO:0006928 335 0.496
Human Zebrafish Mouse
growth plate cartilage development GO:0003417 2 0.496
oligodendrocyte differentiation GO:0048709 23 0.495
response to decreased oxygen levels GO:0036293 25 0.491
negative regulation of signaling GO:0023057 96 0.483
Mouse
renal system vasculature development GO:0061437 2 0.482
positive regulation of nucleic acid templated transcription GO:1903508 57 0.474
Human Zebrafish Mouse
regulation of ossification GO:0030278 5 0.471
Mouse
neural crest cell differentiation GO:0014033 72 0.466
Mouse
blood vessel morphogenesis GO:0048514 216 0.465
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.462
Human Zebrafish Mouse
localization of cell GO:0051674 244 0.456
Human Zebrafish Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.456
Human Mouse
neural crest cell migration GO:0001755 42 0.455
positive regulation of muscle tissue development GO:1901863 1 0.454
defense response GO:0006952 47 0.453
retinal ganglion cell axon guidance GO:0031290 35 0.451
response to hormone GO:0009725 48 0.450
smooth muscle tissue development GO:0048745 1 0.449
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.444
regulation of endothelial cell proliferation GO:0001936 1 0.443
primary neural tube formation GO:0014020 1 0.442
neuron projection guidance GO:0097485 86 0.440
cell migration GO:0016477 237 0.440
Human Zebrafish Mouse
auditory receptor cell fate commitment GO:0009912 4 0.440
trigeminal nerve development GO:0021559 3 0.432
hypothalamus cell differentiation GO:0021979 4 0.429
cardiocyte differentiation GO:0035051 44 0.426
muscle cell differentiation GO:0042692 139 0.424
Mouse
positive regulation of metabolic process GO:0009893 108 0.422
Human Zebrafish Mouse
regulation of skeletal muscle fiber development GO:0048742 2 0.417
Mouse
endodermal cell fate determination GO:0007493 2 0.410
Zebrafish
positive regulation of signaling GO:0023056 56 0.408
Mouse
brain development GO:0007420 293 0.408
otic vesicle morphogenesis GO:0071600 34 0.398
determination of heart left right asymmetry GO:0061371 117 0.387
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.386
Mouse
ear morphogenesis GO:0042471 64 0.386
extracellular structure organization GO:0043062 27 0.382
Mouse
forebrain development GO:0030900 96 0.382
auditory receptor cell differentiation GO:0042491 15 0.379
carbohydrate metabolic process GO:0005975 12 0.379
hematopoietic or lymphoid organ development GO:0048534 191 0.377
gamete generation GO:0007276 33 0.377
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.377
Human Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.371
Mouse
glucose homeostasis GO:0042593 1 0.370
cell projection morphogenesis GO:0048858 244 0.370
negative regulation of response to stimulus GO:0048585 104 0.370
Mouse
skeletal muscle tissue development GO:0007519 67 0.369
Mouse
olfactory bulb development GO:0021772 4 0.361
aging GO:0007568 2 0.358
motor neuron axon guidance GO:0008045 23 0.348
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.347
extracellular matrix organization GO:0030198 27 0.346
Mouse
muscle organ development GO:0007517 101 0.343
Mouse
palate development GO:0060021 8 0.343
Zebrafish
limb morphogenesis GO:0035108 7 0.341
Mouse
regulation of muscle organ development GO:0048634 9 0.337
Mouse
bmp signaling pathway involved in heart development GO:0061312 15 0.336
cell death GO:0008219 121 0.336
Human Mouse
neuron projection development GO:0031175 180 0.331
cellular aromatic compound metabolic process GO:0006725 295 0.323
Human Zebrafish Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.322
Human Zebrafish Mouse
neural tube development GO:0021915 62 0.321
regulation of transcription dna templated GO:0006355 213 0.316
Human Zebrafish Mouse
response to vitamin GO:0033273 3 0.314
determination of bilateral symmetry GO:0009855 204 0.314
Zebrafish
skin development GO:0043588 54 0.313
Mouse
response to organic substance GO:0010033 153 0.313
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.310
Human Zebrafish Mouse
limb bud formation GO:0060174 2 0.309
Mouse
cellular response to hormone stimulus GO:0032870 39 0.304
response to bacterium GO:0009617 58 0.299
oxoacid metabolic process GO:0043436 31 0.294
cranial suture morphogenesis GO:0060363 1 0.290
negative regulation of cellular process GO:0048523 283 0.288
Human Mouse
cartilage condensation GO:0001502 3 0.287
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.284
Human Zebrafish Mouse
cardioblast differentiation GO:0010002 9 0.283
cellular response to organic cyclic compound GO:0071407 38 0.283
rhombomere development GO:0021546 19 0.283
positive regulation of striated muscle cell differentiation GO:0051155 1 0.281
bmp signaling pathway involved in heart jogging GO:0003303 14 0.276
regulation of protein catabolic process GO:0042176 1 0.275
Mouse
negative regulation of muscle organ development GO:0048635 5 0.273
muscle structure development GO:0061061 196 0.273
Mouse
apoptotic process involved in development GO:1902742 2 0.271
generation of neurons GO:0048699 385 0.269
Zebrafish Mouse
negative regulation of axon guidance GO:1902668 1 0.269
cell part morphogenesis GO:0032990 246 0.266
eye development GO:0001654 277 0.265
Zebrafish Mouse
striated muscle tissue development GO:0014706 110 0.264
Mouse
negative regulation of endothelial cell migration GO:0010596 1 0.264
programmed cell death GO:0012501 119 0.259
Human Mouse
definitive hemopoiesis GO:0060216 18 0.253
endocardium formation GO:0060214 1 0.251
regulation of vasculature development GO:1901342 33 0.248
regulation of developmental process GO:0050793 247 0.247
Human Zebrafish Mouse
regulation of organ growth GO:0046620 3 0.247
negative regulation of transcription dna templated GO:0045892 45 0.241
Human Mouse
anterior commissure morphogenesis GO:0021960 3 0.241
hormone metabolic process GO:0042445 19 0.241
olfactory lobe development GO:0021988 4 0.239
endochondral bone growth GO:0003416 2 0.239
neuron projection morphogenesis GO:0048812 161 0.238
apoptotic process GO:0006915 116 0.235
Human Mouse
response to abiotic stimulus GO:0009628 122 0.232
Mouse
vasculogenesis GO:0001570 41 0.231
Zebrafish
androgen metabolic process GO:0008209 2 0.230
smoothened signaling pathway GO:0007224 30 0.228
rhombomere morphogenesis GO:0021593 17 0.227
glycosaminoglycan biosynthetic process GO:0006024 8 0.226
tube morphogenesis GO:0035239 349 0.226
Zebrafish Mouse
branchiomotor neuron axon guidance GO:0021785 1 0.225
positive regulation of skeletal muscle tissue development GO:0048643 1 0.221
foregut morphogenesis GO:0007440 4 0.219
somatic stem cell maintenance GO:0035019 1 0.219
Mouse
epithelial cell morphogenesis GO:0003382 2 0.219
cellular hormone metabolic process GO:0034754 19 0.218
eye photoreceptor cell development GO:0042462 30 0.217
endothelium development GO:0003158 25 0.217
Zebrafish
cranial nerve development GO:0021545 42 0.214
negative regulation of striated muscle tissue development GO:0045843 2 0.214
establishment of protein localization to organelle GO:0072594 4 0.213
wound healing GO:0042060 90 0.210
Zebrafish
nuclear transport GO:0051169 4 0.210
peripheral nervous system neuron differentiation GO:0048934 28 0.210
negative regulation of gene expression GO:0010629 65 0.209
Human Mouse
oligodendrocyte cell fate specification GO:0021778 4 0.207
single organism metabolic process GO:0044710 217 0.205
Mouse
dorsal ventral pattern formation GO:0009953 125 0.204
Zebrafish
kidney vasculature morphogenesis GO:0061439 1 0.204
cellular response to nutrient levels GO:0031669 2 0.202
otic placode formation GO:0043049 23 0.200
response to nutrient GO:0007584 3 0.198
thyroid gland development GO:0030878 12 0.197
polarized epithelial cell differentiation GO:0030859 4 0.196
axis specification GO:0009798 43 0.196
Zebrafish
cranial nerve morphogenesis GO:0021602 15 0.196
neuromast development GO:0048884 46 0.194
head development GO:0060322 303 0.194
female gonad development GO:0008585 4 0.193
larval heart development GO:0007508 2 0.193
nerve development GO:0021675 45 0.190
apoptotic process involved in morphogenesis GO:0060561 2 0.190
er nucleus signaling pathway GO:0006984 2 0.189
limb development GO:0060173 8 0.186
Mouse
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.183
notochord development GO:0030903 54 0.182
Mouse
striated muscle cell development GO:0055002 108 0.181
Mouse
regulation of stem cell proliferation GO:0072091 2 0.179
Mouse
sensory system development GO:0048880 76 0.179
dorsal ventral axis specification GO:0009950 14 0.179
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.178
Mouse
proteoglycan metabolic process GO:0006029 14 0.177
response to organic cyclic compound GO:0014070 51 0.177
nucleocytoplasmic transport GO:0006913 4 0.177
endodermal cell fate specification GO:0001714 17 0.176
Zebrafish
swim bladder morphogenesis GO:0048795 4 0.176
anterior posterior axon guidance GO:0033564 5 0.174
ameboidal type cell migration GO:0001667 143 0.174
Human Zebrafish Mouse
cell fate specification GO:0001708 68 0.173
Zebrafish Mouse
multicellular organismal metabolic process GO:0044236 2 0.172
mitotic cell cycle GO:0000278 64 0.172
head morphogenesis GO:0060323 8 0.170
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.169
embryonic heart tube morphogenesis GO:0003143 108 0.169
epidermal cell differentiation GO:0009913 36 0.169
nephron morphogenesis GO:0072028 2 0.167
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.165
positive regulation of epithelial cell differentiation GO:0030858 2 0.165
Mouse
thymus development GO:0048538 10 0.164
hormone biosynthetic process GO:0042446 3 0.163
bone development GO:0060348 14 0.163
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.162
Human Zebrafish Mouse
anterior posterior pattern specification GO:0009952 152 0.161
chemical homeostasis GO:0048878 49 0.161
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.159
Human Mouse
positive regulation of response to stimulus GO:0048584 80 0.158
Mouse
neuromast hair cell development GO:0035675 6 0.157
single organism nuclear import GO:1902593 3 0.156
single organism transport GO:0044765 206 0.153
organ formation GO:0048645 17 0.153
Zebrafish
eye photoreceptor cell differentiation GO:0001754 45 0.152
Mouse
embryonic epithelial tube formation GO:0001838 17 0.150
Mouse
axon development GO:0061564 166 0.150
regulation of bone mineralization GO:0030500 2 0.150
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.148
Zebrafish Mouse
endothelial cell proliferation GO:0001935 11 0.148
stem cell division GO:0017145 1 0.148
forebrain regionalization GO:0021871 4 0.148
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.146
posterior lateral line nerve development GO:0048918 8 0.146
organ growth GO:0035265 12 0.145
Mouse
female gamete generation GO:0007292 14 0.145
regulation of myotube differentiation GO:0010830 2 0.144
Mouse
endocardium development GO:0003157 9 0.141
negative regulation of epithelial cell migration GO:0010633 1 0.139
axonogenesis GO:0007409 152 0.139
bone morphogenesis GO:0060349 11 0.139
Human Mouse
lipid biosynthetic process GO:0008610 22 0.138
regulation of mesenchymal cell proliferation GO:0010464 1 0.138
Mouse
photoreceptor cell development GO:0042461 40 0.136
glomerular epithelial cell fate commitment GO:0072314 4 0.132
reproduction GO:0000003 40 0.132
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.131
Human Mouse
positive regulation of programmed cell death GO:0043068 29 0.128
negative regulation of biosynthetic process GO:0009890 55 0.128
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.128
Mouse
response to drug GO:0042493 3 0.126
response to metal ion GO:0010038 34 0.125
regulation of nitrogen compound metabolic process GO:0051171 251 0.125
Human Zebrafish Mouse
direct ossification GO:0036072 3 0.125
regulation of response to stimulus GO:0048583 269 0.125
Mouse
negative regulation of signal transduction GO:0009968 94 0.124
Mouse
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.124
negative regulation of smoothened signaling pathway GO:0045879 6 0.123
response to biotic stimulus GO:0009607 97 0.123
response to endogenous stimulus GO:0009719 83 0.121
Human Mouse
post embryonic organ development GO:0048569 4 0.119
multi organism process GO:0051704 134 0.119
Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.117
regulation of cartilage development GO:0061035 7 0.117
Human Zebrafish Mouse
inner ear receptor cell fate commitment GO:0060120 4 0.117
protein complex subunit organization GO:0071822 46 0.117
Human
lipid storage GO:0019915 1 0.115
digestive tract morphogenesis GO:0048546 231 0.114
Zebrafish
regulation of transcription involved in cell fate commitment GO:0060850 1 0.114
response to lipid GO:0033993 60 0.114
Human Mouse
positive regulation of endothelial cell differentiation GO:0045603 2 0.113
embryonic skeletal joint development GO:0072498 3 0.113
segment polarity determination GO:0007367 1 0.112
morphogenesis of embryonic epithelium GO:0016331 30 0.110
Mouse
epithelial tube morphogenesis GO:0060562 148 0.109
Mouse
sensory perception of mechanical stimulus GO:0050954 16 0.109
regulation of macromolecule biosynthetic process GO:0010556 225 0.109
Human Zebrafish Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.108
Zebrafish
positive regulation of multicellular organismal process GO:0051240 52 0.107
Human Mouse
regulation of growth GO:0040008 42 0.107
protein targeting to nucleus GO:0044744 3 0.107
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.105
glial cell migration GO:0008347 3 0.104
neuron fate specification GO:0048665 20 0.104
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.104
Zebrafish
skeletal muscle organ development GO:0060538 78 0.104
Mouse
hemopoiesis GO:0030097 183 0.104
embryonic camera type eye development GO:0031076 29 0.104
glial cell differentiation GO:0010001 42 0.104
positive regulation of rna metabolic process GO:0051254 59 0.103
Human Zebrafish Mouse
heart looping GO:0001947 94 0.102
peripheral nervous system neuron development GO:0048935 22 0.099
peripheral nervous system development GO:0007422 55 0.098
Zebrafish
positive regulation of apoptotic process GO:0043065 29 0.098
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 1 0.098
regulation of locomotion GO:0040012 55 0.096
Human Mouse
wnt signaling pathway GO:0016055 80 0.096
Mouse
nitrogen compound metabolic process GO:0006807 319 0.095
Human Zebrafish Mouse
protein import GO:0017038 3 0.095
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.092
Human Mouse
epithelium migration GO:0090132 25 0.092
Human Mouse
autophagy GO:0006914 4 0.091
development of primary female sexual characteristics GO:0046545 4 0.091
cellular protein localization GO:0034613 20 0.091
Mouse
stem cell development GO:0048864 82 0.090
Mouse
determination of intestine left right asymmetry GO:0071908 2 0.090
organic acid metabolic process GO:0006082 31 0.090
sensory neuron axon guidance GO:0097374 3 0.089
cellular component morphogenesis GO:0032989 336 0.088
Mouse
renal system vasculature morphogenesis GO:0061438 1 0.087
rhombomere boundary formation GO:0021654 10 0.087
negative regulation of reproductive process GO:2000242 3 0.087
regulation of blood circulation GO:1903522 32 0.085
regulation of embryonic development GO:0045995 47 0.085
Zebrafish
negative regulation of muscle cell differentiation GO:0051148 1 0.085
Mouse
distal tubule development GO:0072017 1 0.084
embryonic pectoral fin morphogenesis GO:0035118 24 0.084
epithelial cell differentiation GO:0030855 116 0.083
Zebrafish Mouse
protein import into nucleus GO:0006606 3 0.083
central nervous system neuron development GO:0021954 29 0.083
regulation of cardiac muscle cell differentiation GO:2000725 1 0.083
positive regulation of cellular protein metabolic process GO:0032270 22 0.082
Mouse
protein metabolic process GO:0019538 183 0.082
Mouse
glial cell fate specification GO:0021780 4 0.082
face morphogenesis GO:0060325 6 0.081
transport GO:0006810 220 0.081
positive regulation of striated muscle tissue development GO:0045844 1 0.081
carboxylic acid metabolic process GO:0019752 22 0.081
negative regulation of cellular metabolic process GO:0031324 77 0.080
Human Mouse
proteoglycan biosynthetic process GO:0030166 12 0.080
body morphogenesis GO:0010171 16 0.080
negative regulation of nucleic acid templated transcription GO:1903507 45 0.079
Human Mouse
regulation of epithelial cell migration GO:0010632 5 0.079
Human Mouse
aminoglycan biosynthetic process GO:0006023 8 0.078
regulation of transport GO:0051049 45 0.077
regulation of cell death GO:0010941 103 0.077
Human Mouse
neuromast hair cell differentiation GO:0048886 12 0.076
mucopolysaccharide metabolic process GO:1903510 2 0.075
negative regulation of endodermal cell fate specification GO:0042664 8 0.075
response to other organism GO:0051707 97 0.075
sexual reproduction GO:0019953 36 0.074
Mouse
mechanosensory lateral line system development GO:0048881 49 0.073
regulation of vascular permeability GO:0043114 5 0.073
carbohydrate homeostasis GO:0033500 1 0.073
ovulation cycle GO:0042698 2 0.073
oogenesis GO:0048477 14 0.072
response to retinoic acid GO:0032526 6 0.072
Human Mouse
cellular response to molecule of bacterial origin GO:0071219 3 0.072
specification of organ identity GO:0010092 2 0.072
response to hexose GO:0009746 3 0.072
sprouting angiogenesis GO:0002040 53 0.071
regulation of programmed cell death GO:0043067 101 0.071
Human Mouse
multicellular organismal homeostasis GO:0048871 29 0.071
Mouse
lipid catabolic process GO:0016042 4 0.071
regulation of cellular component organization GO:0051128 86 0.070
Mouse
floor plate formation GO:0021508 12 0.069
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.069
specification of symmetry GO:0009799 204 0.069
Zebrafish
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.068
protein complex assembly GO:0006461 30 0.068
Human
embryonic foregut morphogenesis GO:0048617 1 0.068
response to inorganic substance GO:0010035 38 0.068
cardiogenic plate morphogenesis GO:0003142 1 0.067
regulation of cellular component biogenesis GO:0044087 12 0.067
Mouse
retinoic acid receptor signaling pathway GO:0048384 16 0.067
regulation of binding GO:0051098 3 0.066
positive regulation of neuron death GO:1901216 1 0.066
macromolecular complex subunit organization GO:0043933 74 0.066
Human
myelination of posterior lateral line nerve axons GO:0048932 5 0.065
histone deacetylation GO:0016575 2 0.065
positive regulation of cellular component biogenesis GO:0044089 3 0.065
Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.065
Zebrafish
regulation of heart growth GO:0060420 2 0.064
positive regulation of transcription dna templated GO:0045893 57 0.064
Human Zebrafish Mouse
post embryonic morphogenesis GO:0009886 4 0.063
death GO:0016265 121 0.063
Human Mouse
regulation of biomineral tissue development GO:0070167 2 0.063
Mouse
forebrain dorsal ventral pattern formation GO:0021798 1 0.063
negative regulation of epithelial cell proliferation GO:0050680 1 0.063
Mouse
regulation of striated muscle cell differentiation GO:0051153 6 0.062
Mouse

sox9a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.428
Human
disease of anatomical entity DOID:7 0 0.428
Human
osteochondrodysplasia DOID:2256 0 0.428
Human
connective tissue disease DOID:65 0 0.428
Human
bone development disease DOID:0080006 0 0.428
Human
bone disease DOID:0080001 0 0.428
Human