|
|
apoptotic process
|
GO:0006915 |
116 |
0.644
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.632
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.631
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.630
|
Human Mouse Worm |
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.556
|
|
|
|
organelle fusion
|
GO:0048284 |
3 |
0.538
|
Human Mouse Worm |
|
|
signal transduction
|
GO:0007165 |
455 |
0.537
|
Human Zebrafish Mouse |
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.529
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
24 |
0.508
|
|
|
|
mitochondrial transport
|
GO:0006839 |
2 |
0.494
|
Mouse |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.461
|
Human Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.457
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.451
|
|
|
|
death
|
GO:0016265 |
121 |
0.438
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
4 |
0.427
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.419
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.418
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.416
|
Zebrafish Mouse |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.408
|
Zebrafish Worm |
|
|
cell death
|
GO:0008219 |
121 |
0.403
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.399
|
Mouse |
|
|
single organism membrane fusion
|
GO:0044801 |
2 |
0.397
|
Human Mouse Worm |
|
|
positive regulation of proteolysis
|
GO:0045862 |
10 |
0.380
|
|
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.380
|
Zebrafish Mouse Worm |
|
|
response to transition metal nanoparticle
|
GO:1990267 |
28 |
0.379
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.359
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
12 |
0.352
|
Human Zebrafish Mouse |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.348
|
Zebrafish |
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.348
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.347
|
Human Mouse |
|
|
sensory organ development
|
GO:0007423 |
393 |
0.332
|
Mouse |
|
|
generation of neurons
|
GO:0048699 |
385 |
0.325
|
Mouse |
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
8 |
0.324
|
Zebrafish |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.310
|
Human Worm |
|
|
regulation of mitochondrion organization
|
GO:0010821 |
1 |
0.304
|
Human Worm |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.290
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.288
|
Mouse |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.286
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.285
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.281
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.277
|
Human Zebrafish Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.276
|
|
|
|
proteolysis
|
GO:0006508 |
38 |
0.260
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
2 |
0.256
|
Mouse |
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.250
|
Human Zebrafish Mouse |
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.248
|
|
|
|
viral process
|
GO:0016032 |
1 |
0.246
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.242
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.240
|
Human Mouse |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.238
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.234
|
Zebrafish Mouse Worm |
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.233
|
Zebrafish |
|
|
negative regulation of nuclear division
|
GO:0051784 |
3 |
0.231
|
Zebrafish |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.225
|
Zebrafish Mouse |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.220
|
Mouse |
|
|
eye development
|
GO:0001654 |
277 |
0.219
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
1 |
0.215
|
Worm |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.208
|
Human |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.205
|
Human Zebrafish Mouse |
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.204
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
23 |
0.204
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
23 |
0.203
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.200
|
|
|
|
response to methylmercury
|
GO:0051597 |
11 |
0.197
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.191
|
Zebrafish Mouse |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.188
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.187
|
Human |
|
|
establishment of localization
|
GO:0051234 |
244 |
0.185
|
Human Mouse |
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.180
|
Zebrafish Mouse |
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.178
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.178
|
Zebrafish Mouse |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
10 |
0.177
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.175
|
Mouse |
|
|
immune system process
|
GO:0002376 |
241 |
0.173
|
Human Mouse |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.172
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.171
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.169
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.168
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.166
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.163
|
Worm |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.162
|
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.161
|
Human Zebrafish Mouse |
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.160
|
Human Zebrafish Mouse |
|
|
positive regulation of molecular function
|
GO:0044093 |
33 |
0.158
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.157
|
Zebrafish |
|
|
organelle organization
|
GO:0006996 |
227 |
0.153
|
Human Zebrafish Mouse Worm |
|
|
cellular response to oxygen levels
|
GO:0071453 |
1 |
0.152
|
|
|
|
regulation of cell size
|
GO:0008361 |
29 |
0.150
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.149
|
Mouse |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.149
|
Human Zebrafish Mouse |
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.149
|
Human Zebrafish Mouse Worm |
|
|
transport
|
GO:0006810 |
220 |
0.148
|
Human Mouse |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.147
|
Zebrafish Mouse Worm |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.146
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.146
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.145
|
Mouse |
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.142
|
Mouse Worm |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
10 |
0.142
|
Zebrafish Mouse |
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.142
|
Human Worm |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.141
|
Mouse |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.140
|
Human Mouse Worm |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
4 |
0.138
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.137
|
Human Worm |
|
|
cell migration
|
GO:0016477 |
237 |
0.136
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.135
|
Mouse |
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.133
|
Human Mouse |
|
|
cellular response to radiation
|
GO:0071478 |
4 |
0.132
|
Mouse |
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.129
|
Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
2 |
0.127
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.127
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.124
|
|
|
|
compound eye development
|
GO:0048749 |
2 |
0.122
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.122
|
Zebrafish Mouse Worm |
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.117
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.116
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.116
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.116
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.115
|
Worm |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.114
|
|
|
|
anion transport
|
GO:0006820 |
38 |
0.114
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.113
|
Mouse |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.113
|
Human Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.113
|
Worm |
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
2 |
0.113
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.113
|
Human Worm |
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.111
|
Human Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
62 |
0.108
|
Mouse |
|
|
segmentation
|
GO:0035282 |
97 |
0.106
|
|
|
|
membrane fusion
|
GO:0061025 |
2 |
0.105
|
Human Mouse Worm |
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.103
|
Mouse Worm |
|
|
cell growth
|
GO:0016049 |
57 |
0.103
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.101
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
2 |
0.101
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.101
|
|
|
|
response to cadmium ion
|
GO:0046686 |
14 |
0.100
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.099
|
|
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.098
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.097
|
Zebrafish Mouse Worm |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
10 |
0.097
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.097
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
1 |
0.096
|
Human Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.095
|
Zebrafish Mouse |
|
|
cellular component movement
|
GO:0006928 |
335 |
0.093
|
Mouse |
|
|
thyroid gland development
|
GO:0030878 |
12 |
0.093
|
Zebrafish |
|
|
aging
|
GO:0007568 |
2 |
0.092
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.091
|
Mouse |
|
|
locomotion
|
GO:0040011 |
313 |
0.091
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
20 |
0.090
|
Human Zebrafish Mouse |
|
|
multi organism cellular process
|
GO:0044764 |
2 |
0.090
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.088
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
86 |
0.088
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
2 |
0.087
|
|
|
|
p38mapk cascade
|
GO:0038066 |
1 |
0.087
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.086
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.085
|
Mouse |
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.084
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
25 |
0.084
|
Mouse |
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.084
|
Human Mouse |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.084
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
22 |
0.083
|
|
|
|
ion transport
|
GO:0006811 |
114 |
0.082
|
Human Mouse |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.082
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
13 |
0.082
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.081
|
Mouse Worm |
|
|
gene expression
|
GO:0010467 |
252 |
0.080
|
Human Zebrafish Mouse |
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.080
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.079
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.079
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.079
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.079
|
Mouse |
|
|
autophagy
|
GO:0006914 |
4 |
0.078
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.078
|
Human Zebrafish Worm |
|
|
macroautophagy
|
GO:0016236 |
1 |
0.077
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.077
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
6 |
0.076
|
Mouse |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
23 |
0.076
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.075
|
Human Mouse |
|
|
somitogenesis
|
GO:0001756 |
87 |
0.075
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.075
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.075
|
Mouse Worm |
|
|
development of primary female sexual characteristics
|
GO:0046545 |
4 |
0.074
|
Mouse |
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.074
|
Human Mouse |
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.074
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.074
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
1 |
0.073
|
|
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.073
|
Human Mouse |
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.073
|
Mouse Worm |
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.073
|
Human Zebrafish Mouse |
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.073
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
1 |
0.072
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.072
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.072
|
Mouse |
|
|
response to nutrient
|
GO:0007584 |
3 |
0.071
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.070
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
3 |
0.070
|
Human Mouse |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.069
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.069
|
Worm |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
1 |
0.068
|
Worm |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.066
|
Human Worm |
|
|
apoptotic signaling pathway
|
GO:0097190 |
23 |
0.066
|
Human Zebrafish Mouse |
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.066
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.065
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.064
|
Zebrafish Mouse |
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.064
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
289 |
0.063
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
1 |
0.063
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.063
|
Mouse Worm |
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.063
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.063
|
Zebrafish |
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.062
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
9 |
0.062
|
Zebrafish |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
39 |
0.062
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.061
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.061
|
Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.060
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.060
|
|
|
|
female gonad development
|
GO:0008585 |
4 |
0.060
|
Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.060
|
Mouse |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.059
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.059
|
Mouse |
|
|
ovulation cycle process
|
GO:0022602 |
2 |
0.059
|
Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
3 |
0.058
|
|
|
|
response to virus
|
GO:0009615 |
21 |
0.058
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.057
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.057
|
Mouse |
|
|
developmental cell growth
|
GO:0048588 |
52 |
0.056
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.056
|
Zebrafish Mouse |
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.056
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
10 |
0.055
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
2 |
0.055
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.054
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.054
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
1 |
0.054
|
Mouse |
|
|
negative regulation of cell division
|
GO:0051782 |
4 |
0.054
|
Zebrafish |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.053
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
20 |
0.052
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.052
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.052
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
2 |
0.052
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.052
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.052
|
Human Mouse |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
2 |
0.052
|
Human |
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.052
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.051
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.051
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.050
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
23 |
0.050
|
Human |
|
|
regulation of cell growth
|
GO:0001558 |
29 |
0.049
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.049
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.049
|
Human Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.049
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.049
|
Human Mouse |
|
|
cell motility
|
GO:0048870 |
244 |
0.049
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.049
|
Worm |
|
|
post embryonic organ development
|
GO:0048569 |
4 |
0.049
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
16 |
0.049
|
Zebrafish |
|
|
cell substrate adhesion
|
GO:0031589 |
4 |
0.048
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
1 |
0.047
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.047
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.047
|
Zebrafish Mouse |
|
|
primitive hemopoiesis
|
GO:0060215 |
27 |
0.047
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
4 |
0.047
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.047
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.046
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.046
|
Zebrafish |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.046
|
Mouse |
|
|
cellular amide metabolic process
|
GO:0043603 |
4 |
0.046
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.046
|
|
|
|
regulation of p38mapk cascade
|
GO:1900744 |
1 |
0.046
|
|
|
|
cytokinesis
|
GO:0000910 |
3 |
0.045
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.045
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
3 |
0.045
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.045
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.044
|
Mouse Worm |
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.044
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.044
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.044
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.044
|
|
|
|
pigmentation
|
GO:0043473 |
85 |
0.044
|
Mouse |
|
|
cellular catabolic process
|
GO:0044248 |
27 |
0.044
|
Human Worm |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.044
|
Human Mouse |
|
|
peptide metabolic process
|
GO:0006518 |
1 |
0.044
|
|
|
|
neuron projection extension
|
GO:1990138 |
45 |
0.043
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
4 |
0.043
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.043
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.043
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.043
|
Mouse |
|
|
response to decreased oxygen levels
|
GO:0036293 |
25 |
0.043
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.043
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
1 |
0.042
|
Worm |
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.042
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.042
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.042
|
Mouse |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.042
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.042
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.041
|
Mouse |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
1 |
0.041
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.041
|
Human Worm |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
1 |
0.041
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.041
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.041
|
Mouse |
|
|
single organism localization
|
GO:1902578 |
225 |
0.040
|
Human Mouse |
|
|
negative regulation of signal transduction by p53 class mediator
|
GO:1901797 |
8 |
0.040
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
25 |
0.040
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.040
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.039
|
|
|
|
gtp catabolic process
|
GO:0006184 |
2 |
0.039
|
Worm |
|
|
post embryonic organ morphogenesis
|
GO:0048563 |
1 |
0.039
|
Mouse |
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
4 |
0.039
|
|
|
|
defense response
|
GO:0006952 |
47 |
0.039
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.039
|
|
|
|
zymogen activation
|
GO:0031638 |
3 |
0.039
|
Human Mouse |
|
|
response to metal ion
|
GO:0010038 |
34 |
0.038
|
|
|
|
ovarian follicle development
|
GO:0001541 |
2 |
0.038
|
Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.038
|
Mouse Worm |
|
|
response to topologically incorrect protein
|
GO:0035966 |
2 |
0.038
|
Human |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
2 |
0.038
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.037
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
10 |
0.037
|
Zebrafish |
|
|
regionalization
|
GO:0003002 |
274 |
0.037
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.037
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.036
|
Mouse |
|
|
post embryonic morphogenesis
|
GO:0009886 |
4 |
0.036
|
Mouse |
|
|
biological adhesion
|
GO:0022610 |
40 |
0.036
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
38 |
0.036
|
|
|
|
growth
|
GO:0040007 |
174 |
0.036
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.036
|
|
|
|
axon extension
|
GO:0048675 |
45 |
0.036
|
|
|
|
interaction with host
|
GO:0051701 |
4 |
0.036
|
|
|
|
killing of cells in other organism involved in symbiotic interaction
|
GO:0051883 |
1 |
0.036
|
|
|
|
metal ion transport
|
GO:0030001 |
58 |
0.035
|
Mouse |
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
3 |
0.035
|
|
|
|
glial cell migration
|
GO:0008347 |
3 |
0.034
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.034
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.033
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
20 |
0.033
|
Human |
|
|
negative regulation of autophagy
|
GO:0010507 |
1 |
0.033
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.033
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
14 |
0.032
|
Zebrafish |
|
|
regulation of mapk cascade
|
GO:0043408 |
14 |
0.032
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.032
|
Mouse |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.032
|
Human Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
4 |
0.032
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
7 |
0.032
|
Zebrafish |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.032
|
Worm |
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.032
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.032
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.031
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
30 |
0.031
|
Mouse |
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.031
|
Human Worm |
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.030
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.030
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.030
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
23 |
0.030
|
Human Zebrafish |
|
|
ear development
|
GO:0043583 |
127 |
0.030
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.030
|
Human Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.029
|
|
|
|
centrosome cycle
|
GO:0007098 |
1 |
0.029
|
|
|
|
gastrulation
|
GO:0007369 |
208 |
0.029
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.029
|
Zebrafish Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
1 |
0.029
|
|
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.029
|
Mouse |
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
2 |
0.029
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
2 |
0.029
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
56 |
0.029
|
Mouse |
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.029
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
4 |
0.028
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.028
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
9 |
0.028
|
Mouse |
|
|
angiogenesis
|
GO:0001525 |
158 |
0.028
|
Mouse |
|
|
reproduction
|
GO:0000003 |
40 |
0.028
|
Mouse |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.028
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.028
|
Human Worm |
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.028
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
15 |
0.028
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.028
|
Worm |
|
|
protein import
|
GO:0017038 |
3 |
0.028
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.027
|
|
|
|
intracellular transport
|
GO:0046907 |
32 |
0.027
|
Mouse |
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.027
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.027
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.027
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.027
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.027
|
Worm |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.027
|
|
|
|
appendage development
|
GO:0048736 |
80 |
0.027
|
Mouse |
|
|
regulation of localization
|
GO:0032879 |
104 |
0.027
|
Mouse |
|
|
blood vessel development
|
GO:0001568 |
246 |
0.027
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
16 |
0.027
|
Zebrafish Mouse |
|
|
response to inorganic substance
|
GO:0010035 |
38 |
0.026
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.026
|
|
|
|
response to monosaccharide
|
GO:0034284 |
3 |
0.026
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.026
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.026
|
|
|
|
membrane organization
|
GO:0061024 |
21 |
0.026
|
Human Mouse Worm |
|
|
regulation of hormone secretion
|
GO:0046883 |
2 |
0.026
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.026
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
1 |
0.026
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
22 |
0.026
|
Human Mouse |
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
2 |
0.026
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
1 |
0.025
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
29 |
0.025
|
Human Zebrafish Worm |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.025
|
|
|
|
response to oxygen levels
|
GO:0070482 |
25 |
0.025
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.025
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
38 |
0.025
|
|
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.025
|
Human |
|
|
secondary metabolic process
|
GO:0019748 |
3 |
0.025
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
90 |
0.025
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
1 |
0.025
|
Mouse |
|
|
mitotic nuclear division
|
GO:0007067 |
18 |
0.025
|
Zebrafish |
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.025
|
Mouse |
|
|
gamete generation
|
GO:0007276 |
33 |
0.024
|
Mouse |
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.024
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
9 |
0.024
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
222 |
0.024
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.024
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.024
|
Mouse |
|
|
multicellular organism reproduction
|
GO:0032504 |
35 |
0.024
|
Mouse |
|
|
cell matrix adhesion
|
GO:0007160 |
4 |
0.024
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
21 |
0.024
|
Zebrafish |
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.024
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
2 |
0.024
|
Worm |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.024
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.024
|
Mouse |
|
|
endosome organization
|
GO:0007032 |
2 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
1 |
0.024
|
Mouse |
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.023
|
|
|
|
somite development
|
GO:0061053 |
96 |
0.023
|
|
|
|
single organism membrane organization
|
GO:0044802 |
20 |
0.023
|
Human Mouse Worm |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
38 |
0.023
|
|
|
|
response to alkaloid
|
GO:0043279 |
2 |
0.023
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.023
|
Mouse |
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
3 |
0.023
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.023
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
4 |
0.023
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
3 |
0.022
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
6 |
0.022
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.022
|
|
|
|
macromolecule localization
|
GO:0033036 |
54 |
0.022
|
Mouse |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.022
|
Human |
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.022
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
22 |
0.022
|
|
|
|
double strand break repair
|
GO:0006302 |
3 |
0.022
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
2 |
0.022
|
Human |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
10 |
0.022
|
Zebrafish |
|
|
system process
|
GO:0003008 |
185 |
0.021
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.021
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
28 |
0.021
|
Worm |
|
|
regulation of jun kinase activity
|
GO:0043506 |
3 |
0.021
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.021
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.021
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
25 |
0.021
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
10 |
0.021
|
Zebrafish |
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.021
|
|
|
|
organic anion transport
|
GO:0015711 |
15 |
0.021
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
25 |
0.021
|
Mouse |
|
|
protein localization to plasma membrane
|
GO:0072659 |
1 |
0.021
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.021
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.021
|
|
|
|
negative regulation of reproductive process
|
GO:2000242 |
3 |
0.020
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.020
|
Zebrafish Mouse |
|
|
positive regulation of multi organism process
|
GO:0043902 |
3 |
0.020
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.020
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
4 |
0.020
|
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
2 |
0.020
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.020
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
3 |
0.020
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
2 |
0.020
|
Human |
|
|
dna biosynthetic process
|
GO:0071897 |
3 |
0.020
|
|
|
|
synapse assembly
|
GO:0007416 |
9 |
0.020
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.020
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.020
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.020
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
0 |
0.020
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
1 |
0.020
|
Worm |
|
|
regulation of calcium ion transport
|
GO:0051924 |
2 |
0.020
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.020
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.020
|
Mouse |
|
|
killing of cells of other organism
|
GO:0031640 |
1 |
0.020
|
|
|
|
hormone secretion
|
GO:0046879 |
2 |
0.020
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.019
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
29 |
0.019
|
Worm |
|
|
acyl coa metabolic process
|
GO:0006637 |
1 |
0.019
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
25 |
0.019
|
Zebrafish |
|
|
cell killing
|
GO:0001906 |
2 |
0.019
|
|
|
|
b cell differentiation
|
GO:0030183 |
1 |
0.019
|
Mouse |
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.019
|
Worm |
|
|
regulation of dendrite development
|
GO:0050773 |
3 |
0.019
|
|
|
|
stem cell division
|
GO:0017145 |
1 |
0.019
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.019
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
22 |
0.019
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.019
|
|
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.019
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.019
|
Mouse |
|
|
response to starvation
|
GO:0042594 |
5 |
0.019
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.019
|
Mouse |
|
|
neuron death
|
GO:0070997 |
21 |
0.019
|
Human Mouse |
