Danio rerio

0 known processes

dct

dopachrome tautomerase

(Aliases: MGC158512,trp2,zgc:109860,MGC109860,TRP-2)

dct biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigmentation GO:0043473 85 0.913
Zebrafish Mouse
pigment granule organization GO:0048753 4 0.873
Zebrafish
dopamine biosynthetic process GO:0042416 2 0.807
Zebrafish
developmental pigmentation GO:0048066 48 0.791
Zebrafish Mouse
central nervous system development GO:0007417 387 0.765
Mouse
melanosome organization GO:0032438 4 0.756
Zebrafish
dopamine metabolic process GO:0042417 2 0.749
Zebrafish
regulation of gene expression GO:0010468 265 0.735
catecholamine metabolic process GO:0006584 2 0.721
Zebrafish
pigment cell differentiation GO:0050931 38 0.669
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.669
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 274 0.634
catechol containing compound biosynthetic process GO:0009713 2 0.593
Zebrafish
cellular pigmentation GO:0033059 30 0.584
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.582
Zebrafish Mouse
chordate embryonic development GO:0043009 271 0.572
stem cell differentiation GO:0048863 117 0.563
camera type eye development GO:0043010 222 0.509
regulation of metabolic process GO:0019222 359 0.484
organic substance biosynthetic process GO:1901576 289 0.480
Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 217 0.466
Zebrafish Mouse
muscle organ development GO:0007517 101 0.455
mesenchyme development GO:0060485 127 0.453
negative regulation of biological process GO:0048519 304 0.441
mesenchymal cell differentiation GO:0048762 87 0.407
negative regulation of cellular process GO:0048523 283 0.375
retina development in camera type eye GO:0060041 146 0.370
cell fate commitment GO:0045165 99 0.349
apoptotic signaling pathway GO:0097190 23 0.347
negative regulation of cellular metabolic process GO:0031324 77 0.345
heart development GO:0007507 313 0.338
cellular biosynthetic process GO:0044249 286 0.335
Zebrafish Mouse
epithelial to mesenchymal transition GO:0001837 21 0.320
negative regulation of gene expression GO:0010629 65 0.317
specification of axis polarity GO:0065001 4 0.315
cell fate specification GO:0001708 68 0.315
aromatic amino acid family metabolic process GO:0009072 1 0.307
Zebrafish Mouse
single organism metabolic process GO:0044710 217 0.284
Zebrafish Mouse
negative regulation of metabolic process GO:0009892 86 0.282
neural crest cell differentiation GO:0014033 72 0.277
sensory organ morphogenesis GO:0090596 200 0.273
mesenchymal cell development GO:0014031 78 0.272
organic cyclic compound biosynthetic process GO:1901362 223 0.271
Zebrafish Mouse
melanocyte differentiation GO:0030318 26 0.271
regulation of macromolecule metabolic process GO:0060255 317 0.269
eye development GO:0001654 277 0.265
regulation of signal transduction GO:0009966 225 0.259
embryonic heart tube formation GO:0003144 1 0.256
anterior lateral line nerve development GO:0048909 4 0.255
biosynthetic process GO:0009058 294 0.249
Zebrafish Mouse
neural crest cell migration GO:0001755 42 0.245
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.234
fin development GO:0033333 77 0.230
neuroepithelial cell differentiation GO:0060563 26 0.227
embryonic heart tube morphogenesis GO:0003143 108 0.221
response to external stimulus GO:0009605 264 0.213
blood circulation GO:0008015 87 0.213
signal transduction GO:0007165 455 0.211
response to vitamin GO:0033273 3 0.209
extrinsic apoptotic signaling pathway GO:0097191 3 0.209
negative regulation of nucleic acid templated transcription GO:1903507 45 0.207
gene expression GO:0010467 252 0.207
sensory organ development GO:0007423 393 0.207
melanin metabolic process GO:0006582 2 0.207
Mouse
axial mesoderm development GO:0048318 10 0.207
nucleobase containing compound metabolic process GO:0006139 274 0.202
tyrosine metabolic process GO:0006570 1 0.200
Zebrafish Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.199
nitrogen compound metabolic process GO:0006807 319 0.198
Zebrafish Mouse
striated muscle tissue development GO:0014706 110 0.198
secondary metabolic process GO:0019748 3 0.197
Mouse
pectoral fin development GO:0033339 50 0.196
neural crest cell development GO:0014032 62 0.190
brain development GO:0007420 293 0.187
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.186
heart morphogenesis GO:0003007 156 0.184
negative regulation of macromolecule metabolic process GO:0010605 76 0.176
negative regulation of transcription dna templated GO:0045892 45 0.176
melanin biosynthetic process GO:0042438 1 0.173
Mouse
retinal metabolic process GO:0042574 3 0.169
stem cell fate commitment GO:0048865 1 0.169
lateral line nerve glial cell development GO:0048937 6 0.167
connective tissue development GO:0061448 99 0.167
endocardial cushion formation GO:0003272 2 0.165
negative regulation of rna metabolic process GO:0051253 48 0.161
organic acid metabolic process GO:0006082 31 0.157
Zebrafish Mouse
retinoic acid receptor signaling pathway GO:0048384 16 0.155
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.154
defense response GO:0006952 47 0.152
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.152
inner ear morphogenesis GO:0042472 63 0.150
regulation of cellular biosynthetic process GO:0031326 245 0.148
pigment metabolic process GO:0042440 12 0.147
Mouse
neuron fate specification GO:0048665 20 0.145
regulation of membrane potential GO:0042391 23 0.143
circulatory system process GO:0003013 87 0.141
head development GO:0060322 303 0.139
Mouse
adult behavior GO:0030534 2 0.138
transmission of nerve impulse GO:0019226 19 0.133
response to nutrient GO:0007584 3 0.133
cellular nitrogen compound biosynthetic process GO:0044271 218 0.127
regulation of signaling GO:0023051 235 0.125
somitogenesis GO:0001756 87 0.125
intracellular signal transduction GO:0035556 85 0.124
aging GO:0007568 2 0.122
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.121
multicellular organismal signaling GO:0035637 22 0.121
negative regulation of cell death GO:0060548 60 0.119
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.113
cellular macromolecule metabolic process GO:0044260 391 0.112
response to wounding GO:0009611 116 0.112
negative regulation of protein phosphorylation GO:0001933 4 0.112
carboxylic acid metabolic process GO:0019752 22 0.110
Zebrafish Mouse
endocrine system development GO:0035270 65 0.109
positive regulation of dna metabolic process GO:0051054 1 0.107
auditory receptor cell fate commitment GO:0009912 4 0.106
negative regulation of catalytic activity GO:0043086 21 0.106
stem cell maintenance GO:0019827 4 0.105
response to stress GO:0006950 263 0.105
single organism biosynthetic process GO:0044711 71 0.104
Zebrafish Mouse
morphogenesis of an epithelial fold GO:0060571 1 0.102
vasculature development GO:0001944 278 0.101
skeletal muscle tissue development GO:0007519 67 0.101
inner ear development GO:0048839 126 0.101
gland development GO:0048732 143 0.100
cellular component movement GO:0006928 335 0.098
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.097
regulation of primary metabolic process GO:0080090 311 0.096
rna biosynthetic process GO:0032774 181 0.095
regulation of cell death GO:0010941 103 0.094
heterocycle metabolic process GO:0046483 290 0.094
embryonic heart tube development GO:0035050 133 0.094
auditory receptor cell fate determination GO:0042668 2 0.094
negative regulation of protein kinase activity GO:0006469 4 0.093
nucleoside triphosphate biosynthetic process GO:0009142 2 0.093
embryonic skeletal system development GO:0048706 97 0.093
mesoderm development GO:0007498 88 0.093
death GO:0016265 121 0.093
embryonic pectoral fin morphogenesis GO:0035118 24 0.091
glial cell fate commitment GO:0021781 6 0.090
heterocycle biosynthetic process GO:0018130 215 0.089
central nervous system myelin formation GO:0032289 1 0.089
regulation of cellular metabolic process GO:0031323 320 0.088
regulation of cell communication GO:0010646 232 0.087
axis specification GO:0009798 43 0.086
small molecule biosynthetic process GO:0044283 16 0.085
lateral line nerve development GO:0048892 9 0.084
lipid storage GO:0019915 1 0.083
regionalization GO:0003002 274 0.082
intracellular receptor signaling pathway GO:0030522 30 0.082
urogenital system development GO:0001655 97 0.082
phenol containing compound biosynthetic process GO:0046189 4 0.081
Zebrafish Mouse
posterior lateral line nerve development GO:0048918 8 0.079
oligodendrocyte cell fate commitment GO:0021779 5 0.078
heart contraction GO:0060047 71 0.078
anterior posterior pattern specification GO:0009952 152 0.078
negative regulation of biosynthetic process GO:0009890 55 0.078
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.077
alpha amino acid metabolic process GO:1901605 3 0.077
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.073
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.072
skeletal muscle organ development GO:0060538 78 0.071
lateral line system development GO:0048925 76 0.071
myeloid leukocyte differentiation GO:0002573 15 0.070
embryonic organ development GO:0048568 381 0.070
regulation of cell activation GO:0050865 1 0.069
negative regulation of signal transduction GO:0009968 94 0.068
protein targeting to nucleus GO:0044744 3 0.067
epithelial tube morphogenesis GO:0060562 148 0.066
epithelial cell differentiation GO:0030855 116 0.065
determination of left right asymmetry in diencephalon GO:0035462 4 0.064
negative regulation of apoptotic signaling pathway GO:2001234 10 0.064
catechol containing compound metabolic process GO:0009712 2 0.063
Zebrafish
glial cell migration GO:0008347 3 0.062
somite development GO:0061053 96 0.062
skeletal system development GO:0001501 181 0.061
segmentation GO:0035282 97 0.061
heart looping GO:0001947 94 0.060
hindbrain morphogenesis GO:0021575 22 0.060
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.060
nucleic acid templated transcription GO:0097659 181 0.060
negative regulation of programmed cell death GO:0043069 58 0.059
regulation of programmed cell death GO:0043067 101 0.059
determination of left right symmetry GO:0007368 179 0.059
myelination of posterior lateral line nerve axons GO:0048932 5 0.059
posterior lateral line nerve glial cell development GO:0048941 5 0.059
negative regulation of signaling GO:0023057 96 0.058
apoptotic process GO:0006915 116 0.057
rna metabolic process GO:0016070 219 0.057
pectoral fin morphogenesis GO:0035138 29 0.055
cranial nerve development GO:0021545 42 0.055
negative regulation of kinase activity GO:0033673 4 0.054
neuron differentiation GO:0030182 353 0.053
response to oxygen containing compound GO:1901700 55 0.053
regulation of apoptotic process GO:0042981 98 0.053
ectodermal placode development GO:0071696 37 0.052
iridophore differentiation GO:0050935 9 0.052
Zebrafish
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.052
bone morphogenesis GO:0060349 11 0.051
negative regulation of striated muscle tissue development GO:0045843 2 0.051
lens development in camera type eye GO:0002088 22 0.051
specification of organ axis polarity GO:0010084 2 0.051
glial cell development GO:0021782 20 0.051
determination of bilateral symmetry GO:0009855 204 0.050
regulation of anatomical structure morphogenesis GO:0022603 130 0.050
inner ear receptor cell fate commitment GO:0060120 4 0.050
cellular amine metabolic process GO:0044106 2 0.050
limb bud formation GO:0060174 2 0.049
enteric nervous system development GO:0048484 12 0.049
otic vesicle formation GO:0030916 27 0.048
nerve development GO:0021675 45 0.048
cardiac chamber development GO:0003205 19 0.048
programmed cell death GO:0012501 119 0.048
trabecula formation GO:0060343 2 0.048
cell surface receptor signaling pathway GO:0007166 325 0.048
regulation of epithelial to mesenchymal transition GO:0010717 3 0.047
negative regulation of response to stimulus GO:0048585 104 0.047
regulation of biological quality GO:0065008 263 0.047
proepicardium development GO:0003342 4 0.046
response to organic substance GO:0010033 153 0.046
cardiogenic plate morphogenesis GO:0003142 1 0.045
vesicle organization GO:0016050 6 0.045
Zebrafish
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.045
maintenance of location GO:0051235 4 0.045
ear morphogenesis GO:0042471 64 0.045
regulation of neural retina development GO:0061074 2 0.044
skeletal system morphogenesis GO:0048705 102 0.044
chemical homeostasis GO:0048878 49 0.043
lipid metabolic process GO:0006629 52 0.043
regulation of retina development in camera type eye GO:1902866 2 0.041
sensory system development GO:0048880 76 0.041
response to lipid GO:0033993 60 0.041
endocardium formation GO:0060214 1 0.041
regulation of response to stimulus GO:0048583 269 0.041
action potential GO:0001508 19 0.040
neuroblast fate commitment GO:0014017 1 0.040
regulation of retinoic acid receptor signaling pathway GO:0048385 5 0.039
muscle tissue development GO:0060537 110 0.039
response to acid chemical GO:0001101 17 0.039
epidermal cell fate specification GO:0009957 4 0.038
cellular component morphogenesis GO:0032989 336 0.038
organic substance transport GO:0071702 58 0.038
regulation of biosynthetic process GO:0009889 250 0.038
anterior lateral line nerve glial cell differentiation GO:0048913 3 0.038
posterior lateral line development GO:0048916 38 0.038
nephron morphogenesis GO:0072028 2 0.038
intrinsic apoptotic signaling pathway GO:0097193 20 0.038
system process GO:0003008 185 0.037
regulation of macromolecule biosynthetic process GO:0010556 225 0.037
tissue regeneration GO:0042246 74 0.037
negative regulation of muscle tissue development GO:1901862 2 0.037
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.037
regulation of translational initiation GO:0006446 1 0.037
regulation of epithelial cell proliferation GO:0050678 3 0.037
cellular component assembly GO:0022607 170 0.036
protein metabolic process GO:0019538 183 0.036
neurological system process GO:0050877 62 0.036
cellular protein metabolic process GO:0044267 129 0.036
segment polarity determination GO:0007367 1 0.035
nucleic acid metabolic process GO:0090304 244 0.035
cellular response to external stimulus GO:0071496 2 0.035
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.035
catecholamine biosynthetic process GO:0042423 2 0.034
Zebrafish
forebrain cell migration GO:0021885 1 0.034
cardiac chamber morphogenesis GO:0003206 12 0.034
organic hydroxy compound biosynthetic process GO:1901617 6 0.034
Zebrafish Mouse
negative regulation of rna biosynthetic process GO:1902679 45 0.034
ear development GO:0043583 127 0.034
forebrain neuron fate commitment GO:0021877 1 0.034
determination of intestine left right asymmetry GO:0071908 2 0.034
hepaticobiliary system development GO:0061008 98 0.033
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.033
septum transversum development GO:0003343 4 0.033
response to radiation GO:0009314 51 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.032
determination of heart left right asymmetry GO:0061371 117 0.032
cellular component biogenesis GO:0044085 178 0.032
regulation of protein catabolic process GO:0042176 1 0.032
positive regulation of cell proliferation GO:0008284 15 0.031
Mouse
cellular amino acid metabolic process GO:0006520 7 0.031
Zebrafish Mouse
neuron development GO:0048666 262 0.031
homeostatic process GO:0042592 142 0.031
organonitrogen compound biosynthetic process GO:1901566 47 0.031
Zebrafish
myelination of anterior lateral line nerve axons GO:0048914 3 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
positive regulation of metabolic process GO:0009893 108 0.030
signal transduction in absence of ligand GO:0038034 1 0.030
generation of neurons GO:0048699 385 0.030
Mouse
pancreatic a cell development GO:0003322 2 0.030
specification of organ identity GO:0010092 2 0.030
cellular aldehyde metabolic process GO:0006081 4 0.030
serotonin metabolic process GO:0042428 1 0.030
embryonic skeletal joint development GO:0072498 3 0.029
neural plate anterior posterior regionalization GO:0021999 8 0.029
anterior lateral line nerve glial cell development GO:0048939 3 0.029
isoprenoid biosynthetic process GO:0008299 7 0.029
female sex differentiation GO:0046660 4 0.029
hindbrain development GO:0030902 91 0.029
regulation of apoptotic signaling pathway GO:2001233 12 0.029
positive regulation of epithelial cell proliferation GO:0050679 1 0.029
response to metal ion GO:0010038 34 0.029
response to alkaloid GO:0043279 2 0.028
autonomic nervous system development GO:0048483 19 0.028
b cell differentiation GO:0030183 1 0.027
amine metabolic process GO:0009308 2 0.027
catabolic process GO:0009056 32 0.027
nephron epithelium morphogenesis GO:0072088 1 0.027
heart process GO:0003015 71 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
positive regulation of response to stimulus GO:0048584 80 0.027
negative regulation of catabolic process GO:0009895 3 0.027
nucleoside monophosphate catabolic process GO:0009125 4 0.026
forebrain regionalization GO:0021871 4 0.026
diterpenoid metabolic process GO:0016101 15 0.026
regulation of transcription dna templated GO:0006355 213 0.026
polarized epithelial cell differentiation GO:0030859 4 0.026
regulation of macrophage chemotaxis GO:0010758 1 0.026
photoreceptor cell fate specification GO:0043704 1 0.026
negative regulation of blood circulation GO:1903523 2 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
Zebrafish Mouse
posterior lateral line nerve glial cell differentiation GO:0048931 5 0.026
single organism organelle organization GO:1902589 199 0.026
cardiocyte differentiation GO:0035051 44 0.026
myelination of lateral line nerve axons GO:0048897 5 0.025
development of primary female sexual characteristics GO:0046545 4 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
negative regulation of cell cycle GO:0045786 14 0.025
water homeostasis GO:0030104 4 0.025
anatomical structure homeostasis GO:0060249 36 0.025
fat soluble vitamin metabolic process GO:0006775 4 0.025
xanthophore differentiation GO:0050936 3 0.024
response to chemical GO:0042221 320 0.024
neural plate regionalization GO:0060897 10 0.024
photoreceptor cell fate commitment GO:0046552 1 0.024
diterpenoid biosynthetic process GO:0016102 7 0.024
cellular response to molecule of bacterial origin GO:0071219 3 0.024
stem cell development GO:0048864 82 0.024
gland morphogenesis GO:0022612 13 0.024
positive regulation of biological process GO:0048518 253 0.024
Mouse
anterior lateral line system development GO:0048898 9 0.024
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.023
alcohol biosynthetic process GO:0046165 2 0.023
reactive nitrogen species metabolic process GO:2001057 0 0.023
neuron projection guidance GO:0097485 86 0.023
small molecule metabolic process GO:0044281 77 0.023
Zebrafish Mouse
negative regulation of apoptotic process GO:0043066 55 0.023
negative regulation of nuclear division GO:0051784 3 0.023
neuroblast differentiation GO:0014016 1 0.023
positive regulation of cell death GO:0010942 29 0.023
cell part morphogenesis GO:0032990 246 0.023
regulation of response to stress GO:0080134 36 0.022
cell projection morphogenesis GO:0048858 244 0.022
lymphocyte proliferation GO:0046651 1 0.022
regulation of cellular protein metabolic process GO:0032268 52 0.022
digestive tract morphogenesis GO:0048546 231 0.022
mononuclear cell proliferation GO:0032943 1 0.022
growth plate cartilage development GO:0003417 2 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
organic hydroxy compound metabolic process GO:1901615 16 0.021
Zebrafish Mouse
cellular response to organic substance GO:0071310 105 0.021
pharyngeal muscle development GO:0043282 4 0.021
regulation of reproductive process GO:2000241 4 0.021
b cell activation GO:0042113 2 0.021
regulation of localization GO:0032879 104 0.021
endocardial cushion morphogenesis GO:0003203 3 0.021
regulation of protein metabolic process GO:0051246 56 0.021
axonogenesis GO:0007409 152 0.021
cell proliferation GO:0008283 80 0.021
Mouse
olfactory placode development GO:0071698 12 0.021
ensheathment of neurons GO:0007272 18 0.021
regulation of nucleic acid templated transcription GO:1903506 213 0.021
fin regeneration GO:0031101 51 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
myeloid cell differentiation GO:0030099 86 0.020
appendage development GO:0048736 80 0.020
regulation of skeletal muscle tissue development GO:0048641 4 0.020
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.020
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.020
atrial ventricular junction remodeling GO:0003294 2 0.020
protein localization to membrane GO:0072657 9 0.020
response to fatty acid GO:0070542 5 0.020
camera type eye morphogenesis GO:0048593 108 0.020
trabecula morphogenesis GO:0061383 2 0.020
negative regulation of mitotic cell cycle GO:0045930 11 0.020
central nervous system myelination GO:0022010 2 0.020
intestinal absorption GO:0050892 2 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
erk1 and erk2 cascade GO:0070371 4 0.019
taxis GO:0042330 109 0.019
cartilage development GO:0051216 96 0.019
response to ionizing radiation GO:0010212 6 0.019
notch signaling pathway GO:0007219 35 0.019
lateral line nerve glial cell differentiation GO:0048895 6 0.019
stem cell proliferation GO:0072089 4 0.019
Mouse
lipid digestion GO:0044241 3 0.019
positive regulation of cellular process GO:0048522 201 0.019
Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.019
pigment biosynthetic process GO:0046148 9 0.019
Mouse
neuron projection morphogenesis GO:0048812 161 0.019
central nervous system neuron differentiation GO:0021953 74 0.019
regulation of inflammatory response GO:0050727 2 0.018
otic vesicle development GO:0071599 42 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
positive regulation of inflammatory response GO:0050729 1 0.018
auditory receptor cell fate specification GO:0042667 2 0.018
osteoclast differentiation GO:0030316 1 0.018
nuclear transport GO:0051169 4 0.018
neural tube patterning GO:0021532 33 0.018
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.018
immune system process GO:0002376 241 0.018
negative regulation of cellular protein metabolic process GO:0032269 16 0.018
mitotic dna damage checkpoint GO:0044773 4 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
response to organic cyclic compound GO:0014070 51 0.017
positive regulation of cell activation GO:0050867 1 0.017
multicellular organismal homeostasis GO:0048871 29 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
exocrine system development GO:0035272 28 0.017
chemosensory behavior GO:0007635 1 0.017
regulation of hormone secretion GO:0046883 2 0.017
cellular response to stress GO:0033554 62 0.017
cellular response to hormone stimulus GO:0032870 39 0.017
tissue remodeling GO:0048771 4 0.017
mitotic cell cycle GO:0000278 64 0.017
basement membrane assembly GO:0070831 3 0.017
isoprenoid metabolic process GO:0006720 15 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
lens morphogenesis in camera type eye GO:0002089 7 0.016
cell morphogenesis GO:0000902 289 0.016
primitive hemopoiesis GO:0060215 27 0.016
retinoid metabolic process GO:0001523 15 0.016
paraxial mesoderm morphogenesis GO:0048340 2 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
leukocyte proliferation GO:0070661 1 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
macromolecule modification GO:0043412 111 0.016
vitamin a biosynthetic process GO:0035238 1 0.016
vitamin a metabolic process GO:0006776 1 0.016
autophagy GO:0006914 4 0.016
membrane repolarization GO:0086009 2 0.016
phenol containing compound metabolic process GO:0018958 5 0.016
Zebrafish Mouse
single organism transport GO:0044765 206 0.016
dna metabolic process GO:0006259 27 0.016
cellular response to nutrient levels GO:0031669 2 0.016
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.015
transport GO:0006810 220 0.015
mitotic g2 m transition checkpoint GO:0044818 3 0.015
hard palate development GO:0060022 4 0.015
wnt signaling pathway GO:0016055 80 0.015
vitamin metabolic process GO:0006766 11 0.015
renal tubule morphogenesis GO:0061333 1 0.015
response to endogenous stimulus GO:0009719 83 0.015
muscle structure development GO:0061061 196 0.015
axon development GO:0061564 166 0.015
cellular protein localization GO:0034613 20 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
posterior lateral line system development GO:0048915 46 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
bone remodeling GO:0046849 2 0.015
specification of symmetry GO:0009799 204 0.015
guanosine containing compound catabolic process GO:1901069 2 0.014
response to uv GO:0009411 3 0.014
neuronal action potential GO:0019228 18 0.014
phagocytosis GO:0006909 3 0.014
eye pigmentation GO:0048069 4 0.014
heart trabecula formation GO:0060347 2 0.014
regulation of cell proliferation involved in tissue homeostasis GO:0060784 2 0.014
pathway restricted smad protein phosphorylation GO:0060389 1 0.014
protein acetylation GO:0006473 2 0.014
positive regulation of endothelial cell differentiation GO:0045603 2 0.014
cranial ganglion development GO:0061550 3 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
Mouse
mapk cascade GO:0000165 18 0.014
protein import into nucleus GO:0006606 3 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
response to abiotic stimulus GO:0009628 122 0.013
regulation of rna metabolic process GO:0051252 224 0.013

dct disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
musculoskeletal system disease DOID:17 0 0.025
immune system disease DOID:2914 0 0.023
organ system cancer DOID:0050686 0 0.023
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
nervous system disease DOID:863 0 0.016
cell type cancer DOID:0050687 0 0.015
auditory system disease DOID:2742 0 0.014
sensory system disease DOID:0050155 0 0.014
nonsyndromic deafness DOID:0050563 0 0.014
connective tissue disease DOID:65 0 0.014
bone disease DOID:0080001 0 0.014