Danio rerio

52 known processes

ddx46

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

(Aliases: wu:fb39a03,fb39a03)

ddx46 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.772
cellular macromolecule metabolic process GO:0044260 391 0.716
biosynthetic process GO:0009058 294 0.600
heterocycle metabolic process GO:0046483 290 0.588
nucleobase containing compound metabolic process GO:0006139 274 0.508
nuclear pore organization GO:0006999 2 0.478
cellular nitrogen compound metabolic process GO:0034641 290 0.440
positive regulation of biological process GO:0048518 253 0.407
nucleic acid metabolic process GO:0090304 244 0.406
rna metabolic process GO:0016070 219 0.380
gene expression GO:0010467 252 0.321
positive regulation of transport GO:0051050 2 0.301
nitrogen compound metabolic process GO:0006807 319 0.276
protein localization to nucleus GO:0034504 3 0.270
rna processing GO:0006396 25 0.269
multicellular organism growth GO:0035264 4 0.269
regulation of nitrogen compound metabolic process GO:0051171 251 0.263
cellular component assembly GO:0022607 170 0.260
single organism organelle organization GO:1902589 199 0.245
embryo development ending in birth or egg hatching GO:0009792 271 0.242
regulation of developmental process GO:0050793 247 0.223
protein targeting to nucleus GO:0044744 3 0.218
regulation of rna biosynthetic process GO:2001141 213 0.195
stem cell proliferation GO:0072089 4 0.195
exocrine pancreas development GO:0031017 28 0.194
digestive system development GO:0055123 289 0.178
maternal determination of anterior posterior axis embryo GO:0008358 4 0.173
cellular aromatic compound metabolic process GO:0006725 295 0.167
nuclear import GO:0051170 3 0.166
rna biosynthetic process GO:0032774 181 0.163
nuclear transport GO:0051169 4 0.160
cellular component biogenesis GO:0044085 178 0.158
regulation of nucleocytoplasmic transport GO:0046822 2 0.148
regulation of metabolic process GO:0019222 359 0.146
immune system development GO:0002520 191 0.141
establishment of protein localization to organelle GO:0072594 4 0.139
vasculature development GO:0001944 278 0.134
protein import GO:0017038 3 0.130
transcription from rna polymerase ii promoter GO:0006366 80 0.129
positive regulation of cell cycle GO:0045787 3 0.127
neuroblast proliferation GO:0007405 2 0.126
purine nucleoside monophosphate catabolic process GO:0009128 4 0.123
cellular macromolecule localization GO:0070727 21 0.122
developmental process involved in reproduction GO:0003006 27 0.120
cell cycle arrest GO:0007050 1 0.119
regulation of primary metabolic process GO:0080090 311 0.116
single organism nuclear import GO:1902593 3 0.115
macromolecular complex subunit organization GO:0043933 74 0.113
organic cyclic compound metabolic process GO:1901360 301 0.108
regulation of gene expression GO:0010468 265 0.106
regulation of protein transport GO:0051223 3 0.103
establishment of localization GO:0051234 244 0.102
blood vessel development GO:0001568 246 0.101
atp catabolic process GO:0006200 4 0.101
cellular macromolecular complex assembly GO:0034622 24 0.099
regulation of intracellular protein transport GO:0033157 3 0.097
regulation of cytoplasmic transport GO:1903649 4 0.096
rna splicing GO:0008380 16 0.095
regulation of dendrite morphogenesis GO:0048814 3 0.095
nucleoside monophosphate catabolic process GO:0009125 4 0.094
nucleocytoplasmic transport GO:0006913 4 0.092
developmental growth GO:0048589 166 0.092
nucleobase containing compound biosynthetic process GO:0034654 205 0.089
regulation of mrna processing GO:0050684 3 0.089
regulation of protein import into nucleus GO:0042306 2 0.086
regulation of establishment of protein localization GO:0070201 4 0.085
regulation of multicellular organism growth GO:0040014 4 0.084
regulation of multicellular organismal development GO:2000026 223 0.081
protein import into nucleus GO:0006606 3 0.080
cytokinetic process GO:0032506 2 0.079
oocyte anterior posterior axis specification GO:0007314 4 0.078
regulation of protein catabolic process GO:0042176 1 0.078
transcription dna templated GO:0006351 181 0.078
cytokinesis GO:0000910 3 0.075
cellular biosynthetic process GO:0044249 286 0.075
macromolecular complex assembly GO:0065003 35 0.075
positive regulation of cellular metabolic process GO:0031325 94 0.073
regulation of protein localization to nucleus GO:1900180 2 0.073
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.073
transport GO:0006810 220 0.072
regulation of cellular component organization GO:0051128 86 0.071
regulation of growth GO:0040008 42 0.069
regulation of multicellular organismal process GO:0051239 277 0.068
heart development GO:0007507 313 0.068
embryonic digestive tract development GO:0048566 4 0.067
negative regulation of macromolecule metabolic process GO:0010605 76 0.067
rna splicing via transesterification reactions GO:0000375 10 0.067
chordate embryonic development GO:0043009 271 0.065
intestinal epithelial cell differentiation GO:0060575 3 0.062
organic substance biosynthetic process GO:1901576 289 0.062
embryonic pattern specification GO:0009880 44 0.061
ribonucleoside monophosphate catabolic process GO:0009158 4 0.061
germ cell development GO:0007281 22 0.060
organelle organization GO:0006996 227 0.060
cellular component morphogenesis GO:0032989 336 0.059
macromolecule biosynthetic process GO:0009059 227 0.058
regulation of dendrite development GO:0050773 3 0.058
sensory organ development GO:0007423 393 0.056
axon development GO:0061564 166 0.056
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.056
digestive tract development GO:0048565 265 0.053
small molecule metabolic process GO:0044281 77 0.053
mitotic cell cycle GO:0000278 64 0.053
tube morphogenesis GO:0035239 349 0.052
glucose homeostasis GO:0042593 1 0.051
intracellular mrna localization GO:0008298 1 0.050
cell cycle GO:0007049 93 0.048
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.047
neuron projection morphogenesis GO:0048812 161 0.047
negative regulation of cell cycle GO:0045786 14 0.047
stem cell division GO:0017145 1 0.046
anterior posterior pattern specification GO:0009952 152 0.045
somite development GO:0061053 96 0.045
single organism localization GO:1902578 225 0.045
organonitrogen compound metabolic process GO:1901564 74 0.045
aromatic compound biosynthetic process GO:0019438 217 0.044
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
eye development GO:0001654 277 0.044
positive regulation of cellular process GO:0048522 201 0.044
single organism cellular localization GO:1902580 46 0.043
blood vessel morphogenesis GO:0048514 216 0.043
translational initiation GO:0006413 3 0.041
regulation of macromolecule biosynthetic process GO:0010556 225 0.041
cytoskeleton organization GO:0007010 96 0.041
mrna processing GO:0006397 14 0.040
spermatid differentiation GO:0048515 2 0.040
regulation of nucleic acid templated transcription GO:1903506 213 0.040
growth GO:0040007 174 0.040
regulation of cell growth GO:0001558 29 0.040
heart looping GO:0001947 94 0.039
cell migration GO:0016477 237 0.039
embryonic organ development GO:0048568 381 0.038
lateral inhibition GO:0046331 1 0.038
neuron projection development GO:0031175 180 0.037
regulation of cellular metabolic process GO:0031323 320 0.036
single organism metabolic process GO:0044710 217 0.036
pancreas development GO:0031016 84 0.036
cell surface receptor signaling pathway GO:0007166 325 0.036
signal transduction GO:0007165 455 0.036
regulation of cell differentiation GO:0045595 142 0.036
microtubule based process GO:0007017 60 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.035
cellular component movement GO:0006928 335 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.035
single organism transport GO:0044765 206 0.034
pole plasm assembly GO:0007315 4 0.034
embryonic cranial skeleton morphogenesis GO:0048701 90 0.034
positive regulation of developmental process GO:0051094 50 0.033
organic acid metabolic process GO:0006082 31 0.033
heart morphogenesis GO:0003007 156 0.032
cell cycle process GO:0022402 53 0.032
mrna splicing via spliceosome GO:0000398 10 0.032
negative regulation of chromosome organization GO:2001251 1 0.031
locomotion GO:0040011 313 0.031
spermatid development GO:0007286 2 0.031
nucleic acid templated transcription GO:0097659 181 0.031
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
carbohydrate homeostasis GO:0033500 1 0.030
rna polyadenylation GO:0043631 2 0.030
meiotic nuclear division GO:0007126 4 0.030
angiogenesis GO:0001525 158 0.030
cell morphogenesis GO:0000902 289 0.030
positive regulation of chromosome organization GO:2001252 1 0.030
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.029
response to chemical GO:0042221 320 0.029
somitogenesis GO:0001756 87 0.028
localization of cell GO:0051674 244 0.028
microtubule cytoskeleton organization GO:0000226 33 0.028
death GO:0016265 121 0.028
regulation of chromosome segregation GO:0051983 1 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
dna metabolic process GO:0006259 27 0.027
regulation of cell shape GO:0008360 1 0.027
regulation of binding GO:0051098 3 0.027
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.026
generation of neurons GO:0048699 385 0.026
gland development GO:0048732 143 0.026
aging GO:0007568 2 0.026
positive regulation of catabolic process GO:0009896 4 0.026
embryonic heart tube morphogenesis GO:0003143 108 0.025
hindbrain development GO:0030902 91 0.025
axonogenesis GO:0007409 152 0.025
regulation of rna metabolic process GO:0051252 224 0.025
single organism reproductive process GO:0044702 40 0.025
positive regulation of cell projection organization GO:0031346 9 0.025
cardiac atrium morphogenesis GO:0003209 2 0.025
negative regulation of metabolic process GO:0009892 86 0.025
regulation of catalytic activity GO:0050790 55 0.025
gamete generation GO:0007276 33 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
regulation of synapse organization GO:0050807 3 0.024
regulation of organelle assembly GO:1902115 4 0.024
embryonic digestive tract morphogenesis GO:0048557 3 0.024
cerebellar granular layer formation GO:0021684 3 0.024
regulation of protein complex assembly GO:0043254 3 0.024
regulation of histone methylation GO:0031060 3 0.024
vesicle localization GO:0051648 27 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
gtp catabolic process GO:0006184 2 0.023
regulation of mitotic cell cycle GO:0007346 25 0.023
energy homeostasis GO:0097009 3 0.023
ribonucleoprotein complex biogenesis GO:0022613 13 0.022
regulation of organ growth GO:0046620 3 0.022
response to radiation GO:0009314 51 0.022
regulation of molecular function GO:0065009 70 0.021
negative regulation of epithelial cell proliferation GO:0050680 1 0.021
ribosome assembly GO:0042255 1 0.021
regulation of meiotic cell cycle GO:0051445 1 0.021
regulation of oocyte development GO:0060281 3 0.021
regionalization GO:0003002 274 0.021
response to abiotic stimulus GO:0009628 122 0.021
organism emergence from protective structure GO:0071684 4 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
positive regulation of metabolic process GO:0009893 108 0.021
protein complex disassembly GO:0043241 1 0.021
cellular amine metabolic process GO:0044106 2 0.021
posttranscriptional gene silencing by rna GO:0035194 3 0.020
regulation of protein binding GO:0043393 3 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
hemopoiesis GO:0030097 183 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
actin cytoskeleton organization GO:0030036 63 0.020
homeostasis of number of cells within a tissue GO:0048873 4 0.020
chromatin modification GO:0016568 21 0.020
somatic muscle development GO:0007525 4 0.020
oxoacid metabolic process GO:0043436 31 0.020
cellular localization GO:0051641 97 0.020
neuron differentiation GO:0030182 353 0.020
amine metabolic process GO:0009308 2 0.020
embryonic skeletal system development GO:0048706 97 0.020
signal transduction downstream of smoothened GO:0007227 1 0.020
negative regulation of gene expression GO:0010629 65 0.020
negative regulation of mrna metabolic process GO:1903312 3 0.020
mitotic cell cycle process GO:1903047 48 0.020
regulation of microtubule cytoskeleton organization GO:0070507 3 0.020
programmed cell death GO:0012501 119 0.019
sex determination GO:0007530 1 0.019
protein localization GO:0008104 40 0.019
regulation of cell cycle GO:0051726 52 0.019
cellular ketone metabolic process GO:0042180 11 0.019
regulation of reproductive process GO:2000241 4 0.019
actin filament based process GO:0030029 64 0.019
organic substance transport GO:0071702 58 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.019
response to light stimulus GO:0009416 46 0.019
negative regulation of kinase activity GO:0033673 4 0.019
camera type eye development GO:0043010 222 0.019
peptidyl threonine modification GO:0018210 1 0.019
regulation of developmental growth GO:0048638 38 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
tissue homeostasis GO:0001894 25 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
body morphogenesis GO:0010171 16 0.018
immune system process GO:0002376 241 0.018
cell growth GO:0016049 57 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
retina development in camera type eye GO:0060041 146 0.018
digestive tract morphogenesis GO:0048546 231 0.018
sexual reproduction GO:0019953 36 0.018
adult behavior GO:0030534 2 0.017
ribonucleoprotein complex assembly GO:0022618 5 0.017
neuroblast differentiation GO:0014016 1 0.017
negative regulation of histone modification GO:0031057 1 0.017
polarized epithelial cell differentiation GO:0030859 4 0.017
cellular protein metabolic process GO:0044267 129 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
retina layer formation GO:0010842 24 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of cell cycle process GO:0010564 20 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
mrna metabolic process GO:0016071 20 0.017
terpenoid metabolic process GO:0006721 15 0.017
response to endogenous stimulus GO:0009719 83 0.017
peptidyl lysine methylation GO:0018022 3 0.016
response to stress GO:0006950 263 0.016
negative regulation of transcription dna templated GO:0045892 45 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
regulation of vitamin metabolic process GO:0030656 6 0.016
regulation of translational initiation GO:0006446 1 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.016
reproduction GO:0000003 40 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
gastrulation GO:0007369 208 0.016
mesenchymal cell proliferation GO:0010463 1 0.016
positive regulation of molecular function GO:0044093 33 0.016
homeostatic process GO:0042592 142 0.016
oocyte development GO:0048599 14 0.016
rna 3 end processing GO:0031123 2 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
regulation of mesenchymal cell proliferation GO:0010464 1 0.016
regulation of cell development GO:0060284 100 0.016
protein complex biogenesis GO:0070271 30 0.016
gene silencing by rna GO:0031047 4 0.015
macromolecule localization GO:0033036 54 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
meiotic cell cycle process GO:1903046 3 0.015
cardiac muscle fiber development GO:0048739 3 0.015
cellular protein catabolic process GO:0044257 4 0.015
phosphorus metabolic process GO:0006793 109 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
cardiac atrium development GO:0003230 4 0.015
establishment of localization in cell GO:0051649 77 0.015
muscle cell differentiation GO:0042692 139 0.015
negative regulation of reproductive process GO:2000242 3 0.015
neural precursor cell proliferation GO:0061351 20 0.014
neural plate morphogenesis GO:0001839 7 0.014
regulation of protein targeting GO:1903533 2 0.014
cell proliferation GO:0008283 80 0.014
cerebellar granular layer morphogenesis GO:0021683 3 0.014
cell part morphogenesis GO:0032990 246 0.014
diterpenoid metabolic process GO:0016101 15 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
reproductive process GO:0022414 40 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
definitive hemopoiesis GO:0060216 18 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
regulation of biological quality GO:0065008 263 0.014
circulatory system process GO:0003013 87 0.014
muscle cell migration GO:0014812 4 0.014
mrna polyadenylation GO:0006378 2 0.014
spindle assembly GO:0051225 2 0.013
regulation of response to stimulus GO:0048583 269 0.013
maintenance of location GO:0051235 4 0.013
photoreceptor cell development GO:0042461 40 0.013
intracellular signal transduction GO:0035556 85 0.013
forebrain regionalization GO:0021871 4 0.013
cytoplasm organization GO:0007028 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
neuron development GO:0048666 262 0.013
protein localization to plasma membrane GO:0072659 1 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.013
negative regulation of chromatin modification GO:1903309 1 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
response to uv GO:0009411 3 0.012
neural plate pattern specification GO:0060896 12 0.012
negative regulation of biological process GO:0048519 304 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
chromosome organization involved in meiosis GO:0070192 1 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
multicellular organismal signaling GO:0035637 22 0.012
spermatogenesis GO:0007283 7 0.012
organelle assembly GO:0070925 110 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of synapse assembly GO:0051963 3 0.012
ribonucleoprotein complex subunit organization GO:0071826 8 0.012
nucleus organization GO:0006997 7 0.012
nls bearing protein import into nucleus GO:0006607 1 0.012
regulation of gene expression epigenetic GO:0040029 11 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
reciprocal meiotic recombination GO:0007131 1 0.011
neural crest cell development GO:0014032 62 0.011
rna localization GO:0006403 4 0.011
protein complex subunit organization GO:0071822 46 0.011
t cell differentiation in thymus GO:0033077 6 0.011
single organism intracellular transport GO:1902582 25 0.011
isoprenoid biosynthetic process GO:0008299 7 0.011
blood circulation GO:0008015 87 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
negative regulation of translational initiation GO:0045947 1 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
negative regulation of defense response GO:0031348 2 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
protein depolymerization GO:0051261 1 0.011
response to organic substance GO:0010033 153 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
posttranscriptional gene silencing GO:0016441 3 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
protein metabolic process GO:0019538 183 0.011
mrna transport GO:0051028 2 0.010
aorta development GO:0035904 4 0.010
regulation of isoprenoid metabolic process GO:0019747 6 0.010
negative regulation of rna metabolic process GO:0051253 48 0.010
mitotic nuclear division GO:0007067 18 0.010
spindle organization GO:0007051 5 0.010
cerebellar granule cell differentiation GO:0021707 3 0.010
regulation of protein maturation GO:1903317 10 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.010
fatty acid catabolic process GO:0009062 1 0.010
reproductive structure development GO:0048608 5 0.010
detection of abiotic stimulus GO:0009582 24 0.010
positive regulation of oocyte development GO:0060282 1 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
erythrocyte differentiation GO:0030218 54 0.010
fertilization GO:0009566 3 0.010
retinoid metabolic process GO:0001523 15 0.010

ddx46 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
cardiovascular system disease DOID:1287 0 0.033
myopathy DOID:423 0 0.019
heart disease DOID:114 0 0.019
muscular disease DOID:0080000 0 0.019
cardiomyopathy DOID:0050700 0 0.019
muscle tissue disease DOID:66 0 0.019
musculoskeletal system disease DOID:17 0 0.019
cancer DOID:162 0 0.017
cell type cancer DOID:0050687 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
gastrointestinal system disease DOID:77 0 0.015
organ system cancer DOID:0050686 0 0.012