Danio rerio

42 known processes

her15.1

hairy and enhancer of split-related 15.1

(Aliases: zgc:136520,her15,fk51a02,wu:fk51a02,hes5)

her15.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.991
midbrain hindbrain boundary development GO:0030917 23 0.989
Zebrafish
response to external stimulus GO:0009605 264 0.977
Fly
locomotion GO:0040011 313 0.954
Fly
thalamus development GO:0021794 6 0.911
Zebrafish
generation of neurons GO:0048699 385 0.906
Zebrafish Mouse Rat Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.897
Zebrafish Mouse Rat Fly
brain development GO:0007420 293 0.893
embryo development ending in birth or egg hatching GO:0009792 271 0.854
neuron development GO:0048666 262 0.850
Zebrafish Fly
regulation of mechanoreceptor differentiation GO:0045631 1 0.832
Mouse
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.813
Zebrafish
diencephalon development GO:0021536 58 0.803
Zebrafish
central nervous system neuron differentiation GO:0021953 74 0.800
Rat
neural tube patterning GO:0021532 33 0.799
Zebrafish
regionalization GO:0003002 274 0.792
positive regulation of neural precursor cell proliferation GO:2000179 1 0.788
Fly
regulation of neural precursor cell proliferation GO:2000177 3 0.786
Fly
organic substance biosynthetic process GO:1901576 289 0.769
Zebrafish Mouse Rat Fly
cell projection morphogenesis GO:0048858 244 0.758
Zebrafish Fly
cellular aromatic compound metabolic process GO:0006725 295 0.737
Zebrafish Mouse Rat Fly
head development GO:0060322 303 0.729
somitogenesis GO:0001756 87 0.719
eye development GO:0001654 277 0.713
tyrosine phosphorylation of stat protein GO:0007260 1 0.691
Mouse
gene expression GO:0010467 252 0.672
Zebrafish Mouse Rat Worm Fly
peripheral nervous system neuron axonogenesis GO:0048936 13 0.669
Zebrafish
axonogenesis GO:0007409 152 0.654
Zebrafish
cellular component morphogenesis GO:0032989 336 0.649
Zebrafish Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.646
Zebrafish Mouse Rat Fly
regulation of biosynthetic process GO:0009889 250 0.644
Zebrafish Mouse Rat Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.632
Zebrafish Mouse Rat Fly
startle response GO:0001964 4 0.621
Fly
regulation of inner ear receptor cell differentiation GO:2000980 1 0.619
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.616
Zebrafish Mouse Rat Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.604
Zebrafish Mouse Rat Fly
nucleic acid metabolic process GO:0090304 244 0.602
Zebrafish Mouse Rat Fly
rna biosynthetic process GO:0032774 181 0.600
Zebrafish Mouse Rat Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.595
Zebrafish Mouse Rat Fly
regulation of metabolic process GO:0019222 359 0.594
Zebrafish Mouse Rat Worm Fly
somite development GO:0061053 96 0.569
rostrocaudal neural tube patterning GO:0021903 29 0.562
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.547
Zebrafish Fly
embryonic organ morphogenesis GO:0048562 274 0.546
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.538
Mouse
radial glial cell differentiation GO:0060019 2 0.537
Rat
anterior posterior pattern specification GO:0009952 152 0.536
neuron projection development GO:0031175 180 0.532
Zebrafish Fly
system process GO:0003008 185 0.531
Mouse Fly
regulation of rna metabolic process GO:0051252 224 0.520
Zebrafish Mouse Rat Fly
sensory organ development GO:0007423 393 0.514
cell morphogenesis involved in differentiation GO:0000904 195 0.507
Zebrafish Fly
regulation of neurogenesis GO:0050767 87 0.494
Zebrafish Mouse Rat Fly
regulation of developmental process GO:0050793 247 0.487
Human Zebrafish Mouse Rat Fly
cellular component movement GO:0006928 335 0.483
forebrain development GO:0030900 96 0.478
Zebrafish Mouse Rat
rna metabolic process GO:0016070 219 0.469
Zebrafish Mouse Rat Fly
forebrain generation of neurons GO:0021872 14 0.465
Rat
heterocycle biosynthetic process GO:0018130 215 0.463
Zebrafish Mouse Rat Fly
regulation of oligodendrocyte differentiation GO:0048713 1 0.462
Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.461
Fly
negative regulation of gene expression GO:0010629 65 0.438
Zebrafish Mouse Rat Worm Fly
chordate embryonic development GO:0043009 271 0.437
regulation of cell cycle GO:0051726 52 0.429
Zebrafish
neuron differentiation GO:0030182 353 0.428
Zebrafish Mouse Rat Fly
heterocycle metabolic process GO:0046483 290 0.423
Zebrafish Mouse Rat Fly
regulation of stem cell proliferation GO:0072091 2 0.413
Fly
regulation of gene expression GO:0010468 265 0.406
Zebrafish Mouse Rat Worm Fly
neuron projection morphogenesis GO:0048812 161 0.398
Zebrafish Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.388
Zebrafish Mouse Rat Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.386
Zebrafish Mouse Rat Fly
neuron projection extension GO:1990138 45 0.383
neuromuscular process GO:0050905 7 0.382
Fly
axon development GO:0061564 166 0.378
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.374
Mouse Rat Fly
aromatic compound biosynthetic process GO:0019438 217 0.373
Zebrafish Mouse Rat Fly
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.371
Mouse
cell projection organization GO:0030030 284 0.369
Zebrafish Fly
embryonic organ development GO:0048568 381 0.360
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.357
Zebrafish Mouse Rat Fly
nephron morphogenesis GO:0072028 2 0.355
Mouse
neurological system process GO:0050877 62 0.351
Mouse Fly
neuroblast proliferation GO:0007405 2 0.349
Fly
regulation of multicellular organismal process GO:0051239 277 0.344
Zebrafish Mouse Rat Fly
cell part morphogenesis GO:0032990 246 0.343
Zebrafish Fly
neuron projection guidance GO:0097485 86 0.336
regulation of blood circulation GO:1903522 32 0.334
gastrulation GO:0007369 208 0.330
cellular biosynthetic process GO:0044249 286 0.325
Zebrafish Mouse Rat Fly
organic cyclic compound metabolic process GO:1901360 301 0.324
Zebrafish Mouse Rat Fly
chemotaxis GO:0006935 104 0.317
regulation of cell differentiation GO:0045595 142 0.313
Human Zebrafish Mouse Rat Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.312
Zebrafish
larval development GO:0002164 2 0.312
regulation of myelination GO:0031641 1 0.312
Mouse
stem cell development GO:0048864 82 0.294
Human Mouse Rat
endoderm development GO:0007492 49 0.291
Zebrafish
ameboidal type cell migration GO:0001667 143 0.291
regulation of nucleic acid templated transcription GO:1903506 213 0.281
Zebrafish Mouse Rat Fly
skin development GO:0043588 54 0.280
Mouse Worm
localization of cell GO:0051674 244 0.274
cell migration GO:0016477 237 0.272
cellular response to stress GO:0033554 62 0.270
Fly
cell motility GO:0048870 244 0.269
negative regulation of rna biosynthetic process GO:1902679 45 0.263
Zebrafish Mouse Rat Fly
tube morphogenesis GO:0035239 349 0.262
Mouse
positive regulation of notch signaling pathway GO:0045747 3 0.254
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.254
Mouse
mesoderm development GO:0007498 88 0.254
Fly
nucleic acid templated transcription GO:0097659 181 0.252
Zebrafish Mouse Rat Fly
regulation of rna biosynthetic process GO:2001141 213 0.249
Zebrafish Mouse Rat Fly
stem cell maintenance GO:0019827 4 0.246
Human Mouse Rat
stem cell proliferation GO:0072089 4 0.243
Fly
somite specification GO:0001757 12 0.234
Zebrafish
response to stress GO:0006950 263 0.230
Fly
cell morphogenesis GO:0000902 289 0.226
Zebrafish Fly
transport GO:0006810 220 0.218
positive regulation of biological process GO:0048518 253 0.213
Human Zebrafish Mouse Fly
negative regulation of biological process GO:0048519 304 0.213
Human Zebrafish Mouse Rat Worm Fly
epithelial cell differentiation GO:0030855 116 0.207
Mouse Worm
negative regulation of nucleic acid templated transcription GO:1903507 45 0.206
Zebrafish Mouse Rat Fly
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.206
Mouse
neural precursor cell proliferation GO:0061351 20 0.204
Fly
positive regulation of gene expression GO:0010628 71 0.202
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.199
Mouse Rat Fly
regulation of cell development GO:0060284 100 0.199
Zebrafish Mouse Rat Fly
regulation of nervous system development GO:0051960 90 0.198
Zebrafish Mouse Rat Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.196
Zebrafish Mouse Rat Fly
regulation of glial cell differentiation GO:0045685 4 0.192
Mouse
regulation of system process GO:0044057 40 0.187
regulation of neuron differentiation GO:0045664 56 0.187
Zebrafish Mouse Rat
signal transduction GO:0007165 455 0.186
positive regulation of rna metabolic process GO:0051254 59 0.183
Mouse
astrocyte differentiation GO:0048708 1 0.182
Mouse
proximal distal pattern formation GO:0009954 1 0.181
Mouse
nitrogen compound metabolic process GO:0006807 319 0.178
Zebrafish Mouse Rat Fly
skeletal system morphogenesis GO:0048705 102 0.177
digestive system development GO:0055123 289 0.177
nephron epithelium morphogenesis GO:0072088 1 0.175
Mouse
cell cycle GO:0007049 93 0.174
Zebrafish
notch signaling pathway GO:0007219 35 0.174
regulation of heart contraction GO:0008016 32 0.174
auditory receptor cell fate commitment GO:0009912 4 0.172
Mouse
developmental cell growth GO:0048588 52 0.169
mesenchymal cell differentiation GO:0048762 87 0.168
cell migration involved in gastrulation GO:0042074 79 0.167
taxis GO:0042330 109 0.165
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.163
Zebrafish Mouse Rat Fly
organ formation GO:0048645 17 0.163
Fly
negative regulation of gliogenesis GO:0014014 1 0.159
Mouse
establishment of localization GO:0051234 244 0.157
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.156
Rat
brain morphogenesis GO:0048854 18 0.155
Fly
connective tissue development GO:0061448 99 0.153
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.153
Zebrafish Mouse Rat Fly
axon extension GO:0048675 45 0.150
regulation of cellular metabolic process GO:0031323 320 0.150
Zebrafish Mouse Rat Fly
cognition GO:0050890 1 0.150
regulation of primary metabolic process GO:0080090 311 0.149
Zebrafish Mouse Rat Fly
cell proliferation in forebrain GO:0021846 3 0.143
regulation of transcription dna templated GO:0006355 213 0.142
Zebrafish Mouse Rat Fly
transcription dna templated GO:0006351 181 0.141
Zebrafish Mouse Rat Fly
neural tube development GO:0021915 62 0.139
Zebrafish Mouse
morphogenesis of embryonic epithelium GO:0016331 30 0.139
Mouse
segmentation GO:0035282 97 0.136
axon ensheathment in central nervous system GO:0032291 2 0.133
Mouse
macromolecule biosynthetic process GO:0009059 227 0.133
Zebrafish Mouse Rat Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.130
regulation of macromolecule metabolic process GO:0060255 317 0.128
Zebrafish Mouse Rat Worm Fly
ear development GO:0043583 127 0.127
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.125
Mouse
negative regulation of rna metabolic process GO:0051253 48 0.121
Zebrafish Mouse Rat Fly
transmission of nerve impulse GO:0019226 19 0.120
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.117
maintenance of location GO:0051235 4 0.116
response to chemical GO:0042221 320 0.115
stem cell differentiation GO:0048863 117 0.115
Human Mouse Rat
regulation of axonogenesis GO:0050770 32 0.112
ear morphogenesis GO:0042471 64 0.112
digestive tract morphogenesis GO:0048546 231 0.111
negative regulation of cellular metabolic process GO:0031324 77 0.110
Zebrafish Mouse Rat Fly
axon guidance GO:0007411 86 0.110
cellular macromolecule metabolic process GO:0044260 391 0.109
Zebrafish Mouse Rat Fly
central nervous system myelination GO:0022010 2 0.108
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.107
Zebrafish Mouse Rat Fly
positive regulation of metabolic process GO:0009893 108 0.102
Zebrafish Mouse
negative regulation of cell development GO:0010721 26 0.100
Zebrafish Mouse Rat
ensheathment of neurons GO:0007272 18 0.099
Mouse
heart development GO:0007507 313 0.099
kupffer s vesicle development GO:0070121 50 0.097
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.097
Zebrafish Mouse Rat Fly
regulation of multicellular organismal development GO:2000026 223 0.095
Zebrafish Mouse Rat Fly
gabaergic neuron differentiation GO:0097154 2 0.095
renal tubule morphogenesis GO:0061333 1 0.094
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.092
biosynthetic process GO:0009058 294 0.091
Zebrafish Mouse Rat Fly
compound eye development GO:0048749 2 0.091
Fly
positive regulation of molecular function GO:0044093 33 0.090
Zebrafish
negative regulation of neurogenesis GO:0050768 20 0.089
Zebrafish Mouse Rat
regulation of cell migration GO:0030334 40 0.089
regulation of anatomical structure morphogenesis GO:0022603 130 0.088
gastrulation with mouth forming second GO:0001702 44 0.087
inner ear morphogenesis GO:0042472 63 0.087
carboxylic acid metabolic process GO:0019752 22 0.086
response to light stimulus GO:0009416 46 0.086
homeostatic process GO:0042592 142 0.086
hair cell differentiation GO:0035315 32 0.084
Mouse
death GO:0016265 121 0.083
urogenital system development GO:0001655 97 0.082
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.081
Mouse Rat Fly
developmental growth GO:0048589 166 0.079
neuronal action potential GO:0019228 18 0.079
Mouse
cartilage development GO:0051216 96 0.078
Human Mouse
convergent extension GO:0060026 118 0.077
positive regulation of cell cycle GO:0045787 3 0.077
Zebrafish
telencephalon development GO:0021537 14 0.076
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.075
Zebrafish Mouse Rat Fly
mechanoreceptor differentiation GO:0042490 37 0.074
Mouse
apoptotic process GO:0006915 116 0.074
blood vessel morphogenesis GO:0048514 216 0.073
cell fate specification GO:0001708 68 0.072
Worm
single organism transport GO:0044765 206 0.071
morphogenesis of an epithelial sheet GO:0002011 49 0.070
cell fate commitment GO:0045165 99 0.070
Mouse Worm Fly
regulation of localization GO:0032879 104 0.069
regulation of cellular component movement GO:0051270 55 0.069
behavior GO:0007610 74 0.068
Fly
neural crest cell development GO:0014032 62 0.067
neural crest cell migration GO:0001755 42 0.064
regulation of axon guidance GO:1902667 8 0.064
mesenchymal cell development GO:0014031 78 0.064
nephron development GO:0072006 31 0.063
Mouse
response to abiotic stimulus GO:0009628 122 0.063
cell adhesion GO:0007155 40 0.063
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.063
Mouse
amine metabolic process GO:0009308 2 0.061
single organism metabolic process GO:0044710 217 0.061
embryonic heart tube development GO:0035050 133 0.060
forebrain neuron differentiation GO:0021879 14 0.060
Rat
retina development in camera type eye GO:0060041 146 0.059
negative regulation of metabolic process GO:0009892 86 0.059
Zebrafish Mouse Rat Worm Fly
regulation of neuron projection development GO:0010975 40 0.058
positive regulation of cell communication GO:0010647 56 0.058
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.058
Mouse
phosphorylation GO:0016310 69 0.058
Zebrafish Mouse
cellular component biogenesis GO:0044085 178 0.055
Mouse
negative regulation of biosynthetic process GO:0009890 55 0.055
Zebrafish Mouse Rat Fly
organic acid metabolic process GO:0006082 31 0.055
regulation of cell death GO:0010941 103 0.055
ventricular system development GO:0021591 12 0.054
extrinsic apoptotic signaling pathway GO:0097191 3 0.054
mammillary body development GO:0021767 4 0.054
negative regulation of macromolecule metabolic process GO:0010605 76 0.053
Zebrafish Mouse Rat Worm Fly
epidermal cell differentiation GO:0009913 36 0.053
Mouse Worm
forebrain regionalization GO:0021871 4 0.053
positive regulation of transport GO:0051050 2 0.053
positive regulation of cell proliferation GO:0008284 15 0.051
Human Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.051
kidney epithelium development GO:0072073 23 0.051
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.051
cellular response to external stimulus GO:0071496 2 0.050
multicellular organismal reproductive process GO:0048609 35 0.050
single organism organelle organization GO:1902589 199 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.050
Mouse
immune system process GO:0002376 241 0.050
Rat
blood vessel endothelial cell differentiation GO:0060837 2 0.049
adult behavior GO:0030534 2 0.048
macromolecular complex subunit organization GO:0043933 74 0.048
Mouse
regulation of signal transduction GO:0009966 225 0.048
Mouse
phosphorus metabolic process GO:0006793 109 0.048
Zebrafish Mouse
dorsal ventral pattern formation GO:0009953 125 0.047
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.047
Zebrafish Mouse Rat Fly
gliogenesis GO:0042063 45 0.047
Zebrafish Mouse Rat
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.046
heart contraction GO:0060047 71 0.046
cellular amino acid metabolic process GO:0006520 7 0.046
positive regulation of nucleic acid templated transcription GO:1903508 57 0.046
Mouse
ion transport GO:0006811 114 0.046
regulation of cell projection organization GO:0031344 44 0.045
specification of symmetry GO:0009799 204 0.045
regulation of cell communication GO:0010646 232 0.045
Mouse
neuron fate commitment GO:0048663 26 0.044
Mouse
sequestering of metal ion GO:0051238 3 0.044
oligodendrocyte differentiation GO:0048709 23 0.043
Mouse
positive regulation of catalytic activity GO:0043085 25 0.043
Zebrafish
embryonic pattern specification GO:0009880 44 0.043
Zebrafish
sequestering of calcium ion GO:0051208 3 0.042
habenula development GO:0021986 9 0.042
epidermal cell fate specification GO:0009957 4 0.041
Worm
regulation of cell growth GO:0001558 29 0.041
lateral line system development GO:0048925 76 0.041
regulation of biological quality GO:0065008 263 0.041
Mouse
striated muscle tissue development GO:0014706 110 0.041
multicellular organismal response to stress GO:0033555 2 0.040
neural crest cell differentiation GO:0014033 72 0.040
small molecule metabolic process GO:0044281 77 0.040
kidney development GO:0001822 92 0.040
Mouse
mesenchyme development GO:0060485 127 0.040
nucleocytoplasmic transport GO:0006913 4 0.040
peripheral nervous system neuron development GO:0048935 22 0.040
Zebrafish
endothelial cell development GO:0001885 12 0.039
establishment of endothelial blood brain barrier GO:0014045 2 0.038
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.038
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.038
gland development GO:0048732 143 0.037
determination of bilateral symmetry GO:0009855 204 0.037
cellular response to extracellular stimulus GO:0031668 2 0.037
muscle cell migration GO:0014812 4 0.037
inner ear receptor cell fate commitment GO:0060120 4 0.037
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.037
regulation of programmed cell death GO:0043067 101 0.037
negative regulation of nervous system development GO:0051961 22 0.036
Zebrafish Mouse Rat
single organism localization GO:1902578 225 0.035
vasculogenesis GO:0001570 41 0.035
peptide transport GO:0015833 1 0.035
cell surface receptor signaling pathway GO:0007166 325 0.034
positive regulation of stress activated mapk cascade GO:0032874 3 0.034
multi organism reproductive process GO:0044703 36 0.034
regulation of membrane potential GO:0042391 23 0.034
Mouse
epithelial cell development GO:0002064 42 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
signal transduction in absence of ligand GO:0038034 1 0.034
positive regulation of macromolecule metabolic process GO:0010604 93 0.033
Zebrafish Mouse
regulation of signaling GO:0023051 235 0.033
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.033
Zebrafish Mouse
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.033
Mouse
positive regulation of cellular process GO:0048522 201 0.033
Human Zebrafish Mouse Fly
programmed cell death GO:0012501 119 0.033
regulation of chemotaxis GO:0050920 18 0.032
organelle organization GO:0006996 227 0.032
regulation of nucleoside metabolic process GO:0009118 2 0.032
response to other organism GO:0051707 97 0.032
regulation of locomotion GO:0040012 55 0.031
digestive tract development GO:0048565 265 0.031
cellular ketone metabolic process GO:0042180 11 0.031
biological adhesion GO:0022610 40 0.030
Mouse
establishment of endothelial barrier GO:0061028 3 0.030
renal system development GO:0072001 94 0.030
Mouse
regulation of cell morphogenesis GO:0022604 42 0.029
cellular protein metabolic process GO:0044267 129 0.029
Zebrafish Mouse
axon extension involved in axon guidance GO:0048846 10 0.029
cilium assembly GO:0042384 58 0.029
regulation of growth GO:0040008 42 0.028
positive regulation of cellular biosynthetic process GO:0031328 68 0.028
Mouse
regulation of extent of cell growth GO:0061387 29 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.027
negative chemotaxis GO:0050919 1 0.027
smoothened signaling pathway GO:0007224 30 0.027
Mouse
negative regulation of cellular process GO:0048523 283 0.027
Human Zebrafish Mouse Rat Fly
cell proliferation GO:0008283 80 0.027
Human Fly
negative regulation of axon guidance GO:1902668 1 0.027
regulation of response to stimulus GO:0048583 269 0.027
Mouse Fly
intracellular signal transduction GO:0035556 85 0.027
Mouse
sensory organ morphogenesis GO:0090596 200 0.027
Fly
locomotory behavior GO:0007626 34 0.027
Fly
sensory perception GO:0007600 39 0.027
cell maturation GO:0048469 23 0.027
Mouse
otic vesicle morphogenesis GO:0071600 34 0.026
regulation of gtp catabolic process GO:0033124 2 0.026
inner ear development GO:0048839 126 0.026
Mouse
leukocyte proliferation GO:0070661 1 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.026
Zebrafish Mouse Rat Fly
protein import GO:0017038 3 0.026
nuclear import GO:0051170 3 0.026
protein complex subunit organization GO:0071822 46 0.026
Mouse
cell death GO:0008219 121 0.026
response to wounding GO:0009611 116 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
Mouse
developmental maturation GO:0021700 34 0.025
Mouse
response to temperature stimulus GO:0009266 15 0.025
positive regulation of cell development GO:0010720 25 0.024
Fly
regulation of cell shape GO:0008360 1 0.024
segment specification GO:0007379 12 0.024
Zebrafish Mouse
otolith development GO:0048840 32 0.024
regulation of cell activation GO:0050865 1 0.024
angiogenesis GO:0001525 158 0.024
otolith morphogenesis GO:0032474 8 0.024
regulation of nucleocytoplasmic transport GO:0046822 2 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.024
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.023
cytoskeleton organization GO:0007010 96 0.023
positive regulation of response to stimulus GO:0048584 80 0.023
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.023
Mouse
female gonad development GO:0008585 4 0.023
negative regulation of cell differentiation GO:0045596 46 0.023
Human Zebrafish Mouse Rat
cell proliferation in hindbrain GO:0021534 4 0.023
eye morphogenesis GO:0048592 144 0.023
Fly
inner ear receptor cell differentiation GO:0060113 29 0.023
Mouse
negative regulation of axon extension GO:0030517 7 0.023
bmp signaling pathway GO:0030509 52 0.022
Mouse
fourth ventricle development GO:0021592 8 0.022
forebrain neuron fate commitment GO:0021877 1 0.022
regulation of axon extension GO:0030516 24 0.022
collateral sprouting in absence of injury GO:0048669 4 0.022
epithelial cell fate commitment GO:0072148 11 0.022
Mouse
formation of primary germ layer GO:0001704 62 0.022
camera type eye development GO:0043010 222 0.022
Mouse
embryonic skeletal system development GO:0048706 97 0.022
vasculature development GO:0001944 278 0.022
detection of abiotic stimulus GO:0009582 24 0.021
auditory receptor cell differentiation GO:0042491 15 0.021
Mouse
ventral spinal cord development GO:0021517 35 0.021
cellular localization GO:0051641 97 0.021
anatomical structure homeostasis GO:0060249 36 0.021
circulatory system process GO:0003013 87 0.021
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.021
response to external biotic stimulus GO:0043207 97 0.021
fin development GO:0033333 77 0.021
multicellular organism growth GO:0035264 4 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
negative regulation of immune system process GO:0002683 7 0.020
Rat
cellular component assembly GO:0022607 170 0.020
Mouse
muscle structure development GO:0061061 196 0.020
regulation of behavior GO:0050795 24 0.020
endothelial cell fate commitment GO:0060839 3 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
positive regulation of secretion GO:0051047 1 0.020
neuron fate determination GO:0048664 2 0.020
Mouse
cellular component disassembly GO:0022411 1 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.020
Zebrafish Mouse
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of catalytic activity GO:0050790 55 0.019
Zebrafish
regulation of kinase activity GO:0043549 15 0.019
Zebrafish
dendrite morphogenesis GO:0048813 5 0.019
Fly
phagocytosis engulfment GO:0006911 1 0.019
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.019
Zebrafish
positive regulation of striated muscle tissue development GO:0045844 1 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
response to biotic stimulus GO:0009607 97 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
regulation of cellular component organization GO:0051128 86 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
fin morphogenesis GO:0033334 53 0.019
regulation of jak stat cascade GO:0046425 3 0.019
Mouse
membrane invagination GO:0010324 1 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
b cell activation GO:0042113 2 0.018
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.018
hemopoiesis GO:0030097 183 0.018
Rat
aging GO:0007568 2 0.018
muscle cell differentiation GO:0042692 139 0.018
limb bud formation GO:0060174 2 0.018
response to corticosteroid GO:0031960 1 0.018
regulation of sequestering of calcium ion GO:0051282 4 0.018
regulation of cardiac muscle tissue development GO:0055024 1 0.018
protein modification process GO:0036211 100 0.018
Zebrafish Mouse
muscle tissue development GO:0060537 110 0.018
sensory perception of pain GO:0019233 1 0.017
single organism reproductive process GO:0044702 40 0.017
skeletal system development GO:0001501 181 0.017
Human Mouse
cellular response to hypoxia GO:0071456 1 0.017
protein metabolic process GO:0019538 183 0.017
Zebrafish Mouse
single organism nuclear import GO:1902593 3 0.017
lens development in camera type eye GO:0002088 22 0.017
oxoacid metabolic process GO:0043436 31 0.017
negative regulation of cell projection organization GO:0031345 9 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.017
regulation of immune system process GO:0002682 34 0.017
Rat
forebrain cell migration GO:0021885 1 0.017
regulation of notch signaling pathway GO:0008593 16 0.017
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.017
Rat
exocrine system development GO:0035272 28 0.016
neuron recognition GO:0008038 18 0.016
female sex differentiation GO:0046660 4 0.016
exocrine pancreas development GO:0031017 28 0.016
protein targeting to nucleus GO:0044744 3 0.016
regulation of response to external stimulus GO:0032101 31 0.016
positive regulation of multicellular organismal process GO:0051240 52 0.016
Fly
negative regulation of jnk cascade GO:0046329 1 0.016
regulation of cell motility GO:2000145 46 0.016
regulation of cell size GO:0008361 29 0.016
mitotic cell cycle GO:0000278 64 0.016
multicellular organismal signaling GO:0035637 22 0.016
Mouse
nephron tubule development GO:0072080 4 0.016
Mouse
epiboly GO:0090504 41 0.015
lamellipodium assembly GO:0030032 1 0.015
positive regulation of neurogenesis GO:0050769 24 0.015
Fly
negative regulation of cellular component movement GO:0051271 18 0.015
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.015
pancreatic d cell differentiation GO:0003311 2 0.015
diterpenoid metabolic process GO:0016101 15 0.015
regulation of gtpase activity GO:0043087 2 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
positive regulation of phosphorus metabolic process GO:0010562 21 0.015
Zebrafish Mouse
regulation of bone remodeling GO:0046850 2 0.015
actin cytoskeleton organization GO:0030036 63 0.015
divalent metal ion transport GO:0070838 20 0.015
glial cell development GO:0021782 20 0.015
Mouse
neural retina development GO:0003407 49 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
regulation of tissue remodeling GO:0034103 2 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014

her15.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
disease of cellular proliferation DOID:14566 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
organ system cancer DOID:0050686 0 0.017
cancer DOID:162 0 0.017