Danio rerio

101 known processes

mcl1b

myeloid cell leukemia sequence 1b

(Aliases: zgc:109763)

mcl1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular process GO:0048523 283 0.640
negative regulation of mitosis GO:0045839 3 0.564
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.478
Human Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.459
Zebrafish
negative regulation of nuclear division GO:0051784 3 0.450
response to stress GO:0006950 263 0.402
Human Mouse
protein localization to nucleus GO:0034504 3 0.387
regulation of signaling GO:0023051 235 0.354
Human Zebrafish Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.351
Worm
single organism membrane fusion GO:0044801 2 0.345
Worm
regulation of gtp catabolic process GO:0033124 2 0.315
Worm
negative regulation of biological process GO:0048519 304 0.309
regulation of cysteine type endopeptidase activity GO:2000116 21 0.300
positive regulation of cellular catabolic process GO:0031331 3 0.290
Worm
positive regulation of biological process GO:0048518 253 0.288
Human Zebrafish Mouse Worm
positive regulation of catabolic process GO:0009896 4 0.276
Worm
guanosine containing compound catabolic process GO:1901069 2 0.272
Worm
regulation of metal ion transport GO:0010959 4 0.268
gtp metabolic process GO:0046039 4 0.261
Worm
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.261
Human
establishment of protein localization to organelle GO:0072594 4 0.251
organelle fusion GO:0048284 3 0.250
Worm
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.245
positive regulation of neuron apoptotic process GO:0043525 1 0.244
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.242
regulation of nucleotide catabolic process GO:0030811 2 0.241
Worm
regulation of metabolic process GO:0019222 359 0.240
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.233
Human Mouse
mitochondrion organization GO:0007005 4 0.225
Mouse Worm
nucleocytoplasmic transport GO:0006913 4 0.219
regulation of nitrogen compound metabolic process GO:0051171 251 0.216
Worm
organelle organization GO:0006996 227 0.209
regulation of response to stimulus GO:0048583 269 0.204
Human Zebrafish Mouse
regulation of peptidase activity GO:0052547 23 0.202
regulation of apoptotic process GO:0042981 98 0.201
single organism nuclear import GO:1902593 3 0.200
nuclear import GO:0051170 3 0.197
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.196
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.195
Human
signal transduction GO:0007165 455 0.190
Human Zebrafish Mouse
negative regulation of gene expression GO:0010629 65 0.190
nuclear transport GO:0051169 4 0.189
protein import GO:0017038 3 0.185
apoptotic process GO:0006915 116 0.182
positive regulation of gtpase activity GO:0043547 1 0.180
Worm
regulation of cell death GO:0010941 103 0.174
cell death GO:0008219 121 0.173
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.171
Worm
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.169
Zebrafish
gene expression GO:0010467 252 0.159
protein targeting to nucleus GO:0044744 3 0.157
negative regulation of cell communication GO:0010648 96 0.152
Human Zebrafish
response to organic substance GO:0010033 153 0.146
Human Zebrafish
gland development GO:0048732 143 0.144
Zebrafish
regulation of protein catabolic process GO:0042176 1 0.140
protein import into nucleus GO:0006606 3 0.136
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.132
positive regulation of neuron death GO:1901216 1 0.131
Human Mouse
negative regulation of cell division GO:0051782 4 0.128
regulation of mitochondrion organization GO:0010821 1 0.127
Worm
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.127
Human
cell death in response to oxidative stress GO:0036473 2 0.127
Human Mouse
gtp catabolic process GO:0006184 2 0.127
Worm
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.125
Worm
organonitrogen compound metabolic process GO:1901564 74 0.124
Worm
positive regulation of transport GO:0051050 2 0.122
negative regulation of protein maturation GO:1903318 10 0.121
regulation of response to oxidative stress GO:1902882 2 0.121
Human Mouse
signal transduction in absence of ligand GO:0038034 1 0.121
Human Mouse
response to transition metal nanoparticle GO:1990267 28 0.120
Zebrafish
regulation of protein localization to nucleus GO:1900180 2 0.119
regulation of protein transport GO:0051223 3 0.118
regulation of macromolecule metabolic process GO:0060255 317 0.115
regulation of cell cycle GO:0051726 52 0.115
negative regulation of signaling GO:0023057 96 0.114
Human Zebrafish
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.114
Human Mouse
small molecule metabolic process GO:0044281 77 0.113
Worm
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.109
Zebrafish
regulation of developmental process GO:0050793 247 0.107
Worm
single organism transport GO:0044765 206 0.107
embryo development ending in birth or egg hatching GO:0009792 271 0.105
regulation of protein maturation GO:1903317 10 0.104
response to cadmium ion GO:0046686 14 0.104
Zebrafish
negative regulation of mitotic cell cycle GO:0045930 11 0.104
modulation by virus of host morphology or physiology GO:0019048 1 0.104
response to glucocorticoid GO:0051384 1 0.103
regulation of gtpase activity GO:0043087 2 0.102
Worm
negative regulation of cell cycle GO:0045786 14 0.102
thyroid gland development GO:0030878 12 0.100
Zebrafish
regulation of signal transduction GO:0009966 225 0.099
Human Zebrafish Mouse
cellular response to chemical stimulus GO:0070887 157 0.099
Human Mouse
response to chemical GO:0042221 320 0.098
Human Zebrafish Mouse
immune system development GO:0002520 191 0.098
response to drug GO:0042493 3 0.095
regulation of proteolysis GO:0030162 24 0.094
macromolecule biosynthetic process GO:0009059 227 0.093
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.093
Human
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.093
Human
cell surface receptor signaling pathway GO:0007166 325 0.093
Human Mouse
negative regulation of hydrolase activity GO:0051346 10 0.092
regulation of nucleoside metabolic process GO:0009118 2 0.092
Worm
regulation of primary metabolic process GO:0080090 311 0.091
regulation of nucleic acid templated transcription GO:1903506 213 0.090
proteolysis GO:0006508 38 0.089
death GO:0016265 121 0.088
positive regulation of nucleotide catabolic process GO:0030813 1 0.087
Worm
cellular response to hypoxia GO:0071456 1 0.086
extrinsic apoptotic signaling pathway GO:0097191 3 0.086
Human Mouse
cellular response to oxygen levels GO:0071453 1 0.085
regulation of cellular response to oxidative stress GO:1900407 2 0.084
Human Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.084
negative regulation of protein processing GO:0010955 10 0.083
positive regulation of apoptotic signaling pathway GO:2001235 1 0.082
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.081
regulation of biological quality GO:0065008 263 0.080
Zebrafish
fertilization GO:0009566 3 0.080
regulation of endopeptidase activity GO:0052548 23 0.079
response to inorganic substance GO:0010035 38 0.077
Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.076
programmed cell death GO:0012501 119 0.076
regulation of establishment of protein localization GO:0070201 4 0.074
regulation of intracellular signal transduction GO:1902531 57 0.072
Human Zebrafish Mouse
protein complex localization GO:0031503 1 0.072
cellular response to stress GO:0033554 62 0.071
Human Mouse
regulation of cytoplasmic transport GO:1903649 4 0.069
regulation of protein metabolic process GO:0051246 56 0.069
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.069
response to metal ion GO:0010038 34 0.068
Zebrafish
cellular response to light stimulus GO:0071482 4 0.066
nucleobase containing compound biosynthetic process GO:0034654 205 0.066
transport GO:0006810 220 0.066
amide transport GO:0042886 12 0.065
positive regulation of cell death GO:0010942 29 0.064
Human Zebrafish Mouse
meiotic nuclear division GO:0007126 4 0.064
regulation of programmed cell death GO:0043067 101 0.063
multi organism cellular process GO:0044764 2 0.063
nucleobase containing small molecule metabolic process GO:0055086 32 0.063
Worm
positive regulation of hydrolase activity GO:0051345 13 0.061
Zebrafish Worm
cellular localization GO:0051641 97 0.061
positive regulation of nucleoside metabolic process GO:0045979 1 0.061
Worm
cellular response to decreased oxygen levels GO:0036294 1 0.060
organic cyclic compound metabolic process GO:1901360 301 0.060
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.060
Worm
cellular response to external stimulus GO:0071496 2 0.060
chordate embryonic development GO:0043009 271 0.059
ovulation cycle process GO:0022602 2 0.059
regulation of cell communication GO:0010646 232 0.059
Human Zebrafish Mouse
mitochondrial transport GO:0006839 2 0.059
negative regulation of response to stimulus GO:0048585 104 0.058
Human Zebrafish
regulation of nucleocytoplasmic transport GO:0046822 2 0.058
response to hypoxia GO:0001666 25 0.057
retina development in camera type eye GO:0060041 146 0.057
carboxylic acid metabolic process GO:0019752 22 0.057
regulation of purine nucleotide catabolic process GO:0033121 2 0.057
Worm
negative regulation of protein transport GO:0051224 3 0.056
developmental growth involved in morphogenesis GO:0060560 86 0.055
cellular component movement GO:0006928 335 0.055
organelle fission GO:0048285 23 0.055
negative regulation of intracellular signal transduction GO:1902532 22 0.055
Zebrafish
regulation of muscle contraction GO:0006937 3 0.054
mitotic nuclear division GO:0007067 18 0.054
cellular catabolic process GO:0044248 27 0.053
Worm
regulation of cytokine production GO:0001817 3 0.053
ameboidal type cell migration GO:0001667 143 0.053
single organism metabolic process GO:0044710 217 0.052
Worm
camera type eye development GO:0043010 222 0.052
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.051
purine ribonucleotide metabolic process GO:0009150 27 0.051
Worm
aromatic compound biosynthetic process GO:0019438 217 0.051
nuclear division GO:0000280 23 0.051
peptide transport GO:0015833 1 0.051
aging GO:0007568 2 0.050
positive regulation of apoptotic process GO:0043065 29 0.050
Human Zebrafish Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.050
multicellular organism growth GO:0035264 4 0.050
positive regulation of cellular process GO:0048522 201 0.050
Human Zebrafish Mouse Worm
neuron neuron synaptic transmission GO:0007270 1 0.049
regulation of multicellular organismal development GO:2000026 223 0.049
regulation of nucleotide metabolic process GO:0006140 17 0.048
Worm
anatomical structure homeostasis GO:0060249 36 0.048
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.048
Worm
cellular macromolecule metabolic process GO:0044260 391 0.048
negative regulation of catalytic activity GO:0043086 21 0.048
regulation of oxidative stress induced cell death GO:1903201 2 0.048
Human Mouse
mitochondrion morphogenesis GO:0070584 2 0.048
cellular protein catabolic process GO:0044257 4 0.047
response to hexose GO:0009746 3 0.047
ribose phosphate metabolic process GO:0019693 27 0.046
Worm
biosynthetic process GO:0009058 294 0.046
cellular component disassembly GO:0022411 1 0.045
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.045
regulation of protein targeting GO:1903533 2 0.045
heterocycle metabolic process GO:0046483 290 0.045
Worm
response to decreased oxygen levels GO:0036293 25 0.045
regulation of cell cycle process GO:0010564 20 0.044
growth GO:0040007 174 0.044
regulation of calcium ion transport GO:0051924 2 0.044
positive regulation of multi organism process GO:0043902 3 0.044
disruption of cells of other organism GO:0044364 1 0.044
response to biotic stimulus GO:0009607 97 0.043
negative regulation of cytoplasmic transport GO:1903650 2 0.043
modification by symbiont of host morphology or physiology GO:0044003 4 0.043
stem cell proliferation GO:0072089 4 0.043
blood vessel development GO:0001568 246 0.043
positive regulation of proteolysis GO:0045862 10 0.043
Zebrafish
homeostatic process GO:0042592 142 0.042
Zebrafish
regulation of gene expression GO:0010468 265 0.042
regulation of intracellular protein transport GO:0033157 3 0.042
single organism localization GO:1902578 225 0.041
negative regulation of metabolic process GO:0009892 86 0.041
regulation of organ growth GO:0046620 3 0.040
multicellular organismal homeostasis GO:0048871 29 0.040
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.040
cell migration GO:0016477 237 0.040
response to organic cyclic compound GO:0014070 51 0.040
macromolecule modification GO:0043412 111 0.040
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.040
ubiquitin dependent protein catabolic process GO:0006511 3 0.040
transcription from rna polymerase ii promoter GO:0006366 80 0.039
cognition GO:0050890 1 0.039
negative regulation of endopeptidase activity GO:0010951 10 0.039
negative regulation of programmed cell death GO:0043069 58 0.039
negative regulation of apoptotic signaling pathway GO:2001234 10 0.039
Human Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
Worm
tube morphogenesis GO:0035239 349 0.038
regulation of membrane potential GO:0042391 23 0.038
regulation of cell division GO:0051302 12 0.038
modification of morphology or physiology of other organism GO:0035821 4 0.038
peptide metabolic process GO:0006518 1 0.037
negative regulation of protein import into nucleus GO:0042308 2 0.037
ribonucleotide metabolic process GO:0009259 27 0.037
Worm
long chain fatty acid metabolic process GO:0001676 1 0.037
response to nutrient GO:0007584 3 0.037
transcription dna templated GO:0006351 181 0.037
digestive system development GO:0055123 289 0.037
regulation of organelle organization GO:0033043 29 0.037
protein metabolic process GO:0019538 183 0.036
negative regulation of cellular biosynthetic process GO:0031327 55 0.036
positive regulation of protein complex assembly GO:0031334 2 0.036
cellular response to radiation GO:0071478 4 0.036
maintenance of location GO:0051235 4 0.035
developmental growth GO:0048589 166 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.035
Worm
negative regulation of biosynthetic process GO:0009890 55 0.035
cellular response to dna damage stimulus GO:0006974 24 0.035
Human Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.035
hematopoietic or lymphoid organ development GO:0048534 191 0.035
positive regulation of peptidase activity GO:0010952 10 0.034
Zebrafish
response to oxygen levels GO:0070482 25 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
cellular protein metabolic process GO:0044267 129 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.034
single organism cellular localization GO:1902580 46 0.034
brain development GO:0007420 293 0.034
regulation of synaptic plasticity GO:0048167 1 0.034
system process GO:0003008 185 0.034
negative regulation of secretion by cell GO:1903531 2 0.034
catabolic process GO:0009056 32 0.033
Worm
purine nucleotide metabolic process GO:0006163 27 0.033
Worm
neuron death GO:0070997 21 0.033
Human Mouse
metal ion transport GO:0030001 58 0.033
negative regulation of proteolysis GO:0045861 10 0.032
peptidyl serine modification GO:0018209 2 0.032
positive regulation of programmed cell death GO:0043068 29 0.032
Human Zebrafish Mouse
intracellular signal transduction GO:0035556 85 0.032
Human Zebrafish Mouse
cytokinesis GO:0000910 3 0.032
positive regulation of nucleotide metabolic process GO:0045981 9 0.032
Worm
negative regulation of macromolecule metabolic process GO:0010605 76 0.032
g1 s transition of mitotic cell cycle GO:0000082 1 0.032
blood vessel morphogenesis GO:0048514 216 0.032
regulation of blood pressure GO:0008217 1 0.031
negative regulation of signal transduction GO:0009968 94 0.031
Human Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
regulation of sodium ion transport GO:0002028 2 0.031
embryonic organ development GO:0048568 381 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
negative regulation of rna biosynthetic process GO:1902679 45 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.030
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.030
negative regulation of rna metabolic process GO:0051253 48 0.030
negative regulation of intracellular protein transport GO:0090317 3 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
cellular response to nutrient levels GO:0031669 2 0.030
cellular response to starvation GO:0009267 1 0.030
regulation of molecular function GO:0065009 70 0.029
positive regulation of endopeptidase activity GO:0010950 10 0.029
Zebrafish
regulation of phosphate metabolic process GO:0019220 43 0.029
Worm
response to oxygen containing compound GO:1901700 55 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
phagocytosis GO:0006909 3 0.029
phosphorus metabolic process GO:0006793 109 0.028
Worm
regulation of protein complex assembly GO:0043254 3 0.028
response to radiation GO:0009314 51 0.028
cellular response to endogenous stimulus GO:0071495 68 0.028
adult behavior GO:0030534 2 0.028
cell motility GO:0048870 244 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
cellular response to lipopolysaccharide GO:0071222 3 0.028
rna biosynthetic process GO:0032774 181 0.028
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.028
regulation of binding GO:0051098 3 0.027
response to hormone GO:0009725 48 0.027
response to lipid GO:0033993 60 0.027
regulation of mitotic cell cycle GO:0007346 25 0.027
response to virus GO:0009615 21 0.027
regulation of biosynthetic process GO:0009889 250 0.027
regulation of neuron apoptotic process GO:0043523 17 0.027
Human Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.027
Worm
meiosis i GO:0007127 1 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.026
larval development GO:0002164 2 0.026
locomotion GO:0040011 313 0.026
localization of cell GO:0051674 244 0.026
regulation of dna templated transcription in response to stress GO:0043620 0 0.026
negative regulation of organelle organization GO:0010639 4 0.026
reactive oxygen species metabolic process GO:0072593 6 0.026
apoptotic process involved in morphogenesis GO:0060561 2 0.026
establishment of localization GO:0051234 244 0.026
negative regulation of kinase activity GO:0033673 4 0.026
amine metabolic process GO:0009308 2 0.026
nucleic acid metabolic process GO:0090304 244 0.026
organic acid metabolic process GO:0006082 31 0.026
response to methylmercury GO:0051597 11 0.025
Zebrafish
response to abiotic stimulus GO:0009628 122 0.025
positive regulation of blood circulation GO:1903524 2 0.025
positive regulation of signal transduction GO:0009967 56 0.025
Human Mouse
reactive oxygen species biosynthetic process GO:1903409 1 0.025
regulation of rna metabolic process GO:0051252 224 0.025
negative regulation of cell death GO:0060548 60 0.025
positive regulation of signaling GO:0023056 56 0.025
Human Mouse
regulation of cellular protein catabolic process GO:1903362 1 0.025
cellular response to organic substance GO:0071310 105 0.025
negative regulation of peptidase activity GO:0010466 10 0.025
cellular biosynthetic process GO:0044249 286 0.025
generation of neurons GO:0048699 385 0.025
negative regulation of molecular function GO:0044092 23 0.025
response to corticosteroid GO:0031960 1 0.025
response to carbohydrate GO:0009743 3 0.025
peptidyl serine phosphorylation GO:0018105 1 0.024
positive regulation of developmental process GO:0051094 50 0.024
Worm
regulation of carbohydrate metabolic process GO:0006109 4 0.024
female sex differentiation GO:0046660 4 0.024
nucleic acid templated transcription GO:0097659 181 0.024
angiogenesis GO:0001525 158 0.024
regeneration GO:0031099 91 0.024
sensory organ development GO:0007423 393 0.024
negative regulation of cellular component organization GO:0051129 16 0.024
vasculature development GO:0001944 278 0.024
post embryonic morphogenesis GO:0009886 4 0.024
apoptotic process involved in development GO:1902742 2 0.024
morphogenesis of an epithelium GO:0002009 333 0.023
positive regulation of epithelial cell proliferation GO:0050679 1 0.023
single organism biosynthetic process GO:0044711 71 0.023
immune system process GO:0002376 241 0.023
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.023
regulation of localization GO:0032879 104 0.023
regulation of rna biosynthetic process GO:2001141 213 0.022
regulation of tube size GO:0035150 2 0.022
positive regulation of cell cycle GO:0045787 3 0.022
response to bacterium GO:0009617 58 0.022
response to other organism GO:0051707 97 0.022
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
organic substance transport GO:0071702 58 0.022
regulation of blood vessel size GO:0050880 2 0.022
neurological system process GO:0050877 62 0.022
positive regulation of dna metabolic process GO:0051054 1 0.022
regulation of ion transport GO:0043269 22 0.022
response to nitrogen compound GO:1901698 19 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.022
positive regulation of cell killing GO:0031343 2 0.021
nucleoside phosphate metabolic process GO:0006753 28 0.021
Worm
protein complex disassembly GO:0043241 1 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
multicellular organismal metabolic process GO:0044236 2 0.021
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cell cycle process GO:0022402 53 0.021
regionalization GO:0003002 274 0.021
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.021
positive regulation of immune effector process GO:0002699 3 0.020
cytosolic calcium ion transport GO:0060401 3 0.020
notch signaling pathway GO:0007219 35 0.020
myeloid cell differentiation GO:0030099 86 0.020
negative regulation of myeloid cell differentiation GO:0045638 1 0.020
viral process GO:0016032 1 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
response to endogenous stimulus GO:0009719 83 0.020
digestive tract development GO:0048565 265 0.020
membrane fusion GO:0061025 2 0.020
Worm
regulation of transport GO:0051049 45 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
skeletal system development GO:0001501 181 0.020
toll like receptor signaling pathway GO:0002224 4 0.020
developmental programmed cell death GO:0010623 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.019
energy reserve metabolic process GO:0006112 2 0.019
embryonic skeletal system development GO:0048706 97 0.019
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
tissue homeostasis GO:0001894 25 0.019
Zebrafish
meiotic cell cycle process GO:1903046 3 0.019
intracellular transport GO:0046907 32 0.019
interaction with host GO:0051701 4 0.019
regulation of heart growth GO:0060420 2 0.019
purine ribonucleoside metabolic process GO:0046128 10 0.019
Worm
regulation of hormone secretion GO:0046883 2 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.019
Worm
cytoskeleton organization GO:0007010 96 0.019
negative regulation of nucleic acid templated transcription GO:1903507 45 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of response to biotic stimulus GO:0002831 2 0.018
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.018
ion transport GO:0006811 114 0.018
organophosphate metabolic process GO:0019637 37 0.018
Worm
reproduction GO:0000003 40 0.018
regulation of transcription dna templated GO:0006355 213 0.018
hemopoiesis GO:0030097 183 0.018
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.018
organic substance biosynthetic process GO:1901576 289 0.018
regulation of mitosis GO:0007088 9 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
Worm
female gonad development GO:0008585 4 0.018
nitrogen compound transport GO:0071705 23 0.018
negative regulation of cell cycle process GO:0010948 9 0.018
cell type specific apoptotic process GO:0097285 22 0.018
Human Mouse
cell proliferation GO:0008283 80 0.017
lipid storage GO:0019915 1 0.017
regulation of apoptotic signaling pathway GO:2001233 12 0.017
Human Zebrafish Mouse
cation transport GO:0006812 81 0.017
cellular response to unfolded protein GO:0034620 2 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
fatty acid biosynthetic process GO:0006633 4 0.017
response to topologically incorrect protein GO:0035966 2 0.017
protein dephosphorylation GO:0006470 3 0.017
cell cycle GO:0007049 93 0.017
endocrine system development GO:0035270 65 0.017
Zebrafish
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
response to light stimulus GO:0009416 46 0.017
organ regeneration GO:0031100 1 0.017
regulation of purine nucleotide metabolic process GO:1900542 17 0.017
Worm
cellular response to hormone stimulus GO:0032870 39 0.017
eye development GO:0001654 277 0.017
convergent extension GO:0060026 118 0.017
telomere maintenance GO:0000723 1 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
Zebrafish
mitotic cell cycle GO:0000278 64 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.016
negative regulation of hormone secretion GO:0046888 2 0.016
response to amino acid GO:0043200 2 0.016
protein polyubiquitination GO:0000209 4 0.016
regulation of dendrite development GO:0050773 3 0.016
oxoacid metabolic process GO:0043436 31 0.016
negative regulation of response to cytokine stimulus GO:0060761 2 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
regulation of wound healing GO:0061041 2 0.016
negative regulation of response to dna damage stimulus GO:2001021 3 0.016
er nucleus signaling pathway GO:0006984 2 0.016
positive regulation of cytokine production GO:0001819 2 0.016
regulation of protein processing GO:0070613 10 0.016
ovarian follicle development GO:0001541 2 0.016
chemosensory behavior GO:0007635 1 0.016
camera type eye morphogenesis GO:0048593 108 0.016
regulation of lipid transport GO:0032368 4 0.016
single organism intracellular transport GO:1902582 25 0.016
response to uv GO:0009411 3 0.015
digestive tract morphogenesis GO:0048546 231 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
carbohydrate homeostasis GO:0033500 1 0.015
dna metabolic process GO:0006259 27 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
cellular amide metabolic process GO:0043603 4 0.015
response to external stimulus GO:0009605 264 0.015
phosphorylation GO:0016310 69 0.015
negative regulation of protein localization to nucleus GO:1900181 2 0.015
hepaticobiliary system development GO:0061008 98 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Zebrafish Worm
neuron apoptotic process GO:0051402 20 0.015
Human Mouse
negative regulation of map kinase activity GO:0043407 2 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.015
response to glucose GO:0009749 3 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
biomineral tissue development GO:0031214 13 0.015
regulation of sterol transport GO:0032371 3 0.014

mcl1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
organ system cancer DOID:0050686 0 0.028