|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.640
|
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.564
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.478
|
Human Mouse |
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
10 |
0.459
|
Zebrafish |
|
negative regulation of nuclear division
|
GO:0051784 |
3 |
0.450
|
|
|
response to stress
|
GO:0006950 |
263 |
0.402
|
Human Mouse |
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.387
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.354
|
Human Zebrafish Mouse |
|
positive regulation of gtp catabolic process
|
GO:0033126 |
1 |
0.351
|
Worm |
|
single organism membrane fusion
|
GO:0044801 |
2 |
0.345
|
Worm |
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.315
|
Worm |
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.309
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
21 |
0.300
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.290
|
Worm |
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.288
|
Human Zebrafish Mouse Worm |
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.276
|
Worm |
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.272
|
Worm |
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.268
|
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.261
|
Worm |
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
1 |
0.261
|
Human |
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.251
|
|
|
organelle fusion
|
GO:0048284 |
3 |
0.250
|
Worm |
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
7 |
0.245
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.244
|
Human Mouse |
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.242
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.241
|
Worm |
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.240
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
2 |
0.233
|
Human Mouse |
|
mitochondrion organization
|
GO:0007005 |
4 |
0.225
|
Mouse Worm |
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.219
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.216
|
Worm |
|
organelle organization
|
GO:0006996 |
227 |
0.209
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.204
|
Human Zebrafish Mouse |
|
regulation of peptidase activity
|
GO:0052547 |
23 |
0.202
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.201
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.200
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.197
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
8 |
0.196
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.195
|
Human |
|
signal transduction
|
GO:0007165 |
455 |
0.190
|
Human Zebrafish Mouse |
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.190
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.189
|
|
|
protein import
|
GO:0017038 |
3 |
0.185
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.182
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
1 |
0.180
|
Worm |
|
regulation of cell death
|
GO:0010941 |
103 |
0.174
|
|
|
cell death
|
GO:0008219 |
121 |
0.173
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.171
|
Worm |
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
10 |
0.169
|
Zebrafish |
|
gene expression
|
GO:0010467 |
252 |
0.159
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.157
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.152
|
Human Zebrafish |
|
response to organic substance
|
GO:0010033 |
153 |
0.146
|
Human Zebrafish |
|
gland development
|
GO:0048732 |
143 |
0.144
|
Zebrafish |
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.140
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.136
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
20 |
0.132
|
|
|
positive regulation of neuron death
|
GO:1901216 |
1 |
0.131
|
Human Mouse |
|
negative regulation of cell division
|
GO:0051782 |
4 |
0.128
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
1 |
0.127
|
Worm |
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
2 |
0.127
|
Human |
|
cell death in response to oxidative stress
|
GO:0036473 |
2 |
0.127
|
Human Mouse |
|
gtp catabolic process
|
GO:0006184 |
2 |
0.127
|
Worm |
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
9 |
0.125
|
Worm |
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.124
|
Worm |
|
positive regulation of transport
|
GO:0051050 |
2 |
0.122
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
10 |
0.121
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
2 |
0.121
|
Human Mouse |
|
signal transduction in absence of ligand
|
GO:0038034 |
1 |
0.121
|
Human Mouse |
|
response to transition metal nanoparticle
|
GO:1990267 |
28 |
0.120
|
Zebrafish |
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.119
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.118
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.115
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.115
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.114
|
Human Zebrafish |
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
2 |
0.114
|
Human Mouse |
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.113
|
Worm |
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
8 |
0.109
|
Zebrafish |
|
regulation of developmental process
|
GO:0050793 |
247 |
0.107
|
Worm |
|
single organism transport
|
GO:0044765 |
206 |
0.107
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.105
|
|
|
regulation of protein maturation
|
GO:1903317 |
10 |
0.104
|
|
|
response to cadmium ion
|
GO:0046686 |
14 |
0.104
|
Zebrafish |
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
11 |
0.104
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
1 |
0.104
|
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.103
|
|
|
regulation of gtpase activity
|
GO:0043087 |
2 |
0.102
|
Worm |
|
negative regulation of cell cycle
|
GO:0045786 |
14 |
0.102
|
|
|
thyroid gland development
|
GO:0030878 |
12 |
0.100
|
Zebrafish |
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.099
|
Human Zebrafish Mouse |
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.099
|
Human Mouse |
|
response to chemical
|
GO:0042221 |
320 |
0.098
|
Human Zebrafish Mouse |
|
immune system development
|
GO:0002520 |
191 |
0.098
|
|
|
response to drug
|
GO:0042493 |
3 |
0.095
|
|
|
regulation of proteolysis
|
GO:0030162 |
24 |
0.094
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.093
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
1 |
0.093
|
Human |
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.093
|
Human |
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.093
|
Human Mouse |
|
negative regulation of hydrolase activity
|
GO:0051346 |
10 |
0.092
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.092
|
Worm |
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.091
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.090
|
|
|
proteolysis
|
GO:0006508 |
38 |
0.089
|
|
|
death
|
GO:0016265 |
121 |
0.088
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
1 |
0.087
|
Worm |
|
cellular response to hypoxia
|
GO:0071456 |
1 |
0.086
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.086
|
Human Mouse |
|
cellular response to oxygen levels
|
GO:0071453 |
1 |
0.085
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
2 |
0.084
|
Human Mouse |
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.084
|
|
|
negative regulation of protein processing
|
GO:0010955 |
10 |
0.083
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.082
|
Human Mouse |
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.081
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.080
|
Zebrafish |
|
fertilization
|
GO:0009566 |
3 |
0.080
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
23 |
0.079
|
|
|
response to inorganic substance
|
GO:0010035 |
38 |
0.077
|
Zebrafish |
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.076
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.076
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.074
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.072
|
Human Zebrafish Mouse |
|
protein complex localization
|
GO:0031503 |
1 |
0.072
|
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.071
|
Human Mouse |
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.069
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.069
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
4 |
0.069
|
|
|
response to metal ion
|
GO:0010038 |
34 |
0.068
|
Zebrafish |
|
cellular response to light stimulus
|
GO:0071482 |
4 |
0.066
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.066
|
|
|
transport
|
GO:0006810 |
220 |
0.066
|
|
|
amide transport
|
GO:0042886 |
12 |
0.065
|
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.064
|
Human Zebrafish Mouse |
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.064
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.063
|
|
|
multi organism cellular process
|
GO:0044764 |
2 |
0.063
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
32 |
0.063
|
Worm |
|
positive regulation of hydrolase activity
|
GO:0051345 |
13 |
0.061
|
Zebrafish Worm |
|
cellular localization
|
GO:0051641 |
97 |
0.061
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
1 |
0.061
|
Worm |
|
cellular response to decreased oxygen levels
|
GO:0036294 |
1 |
0.060
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.060
|
Worm |
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.060
|
Worm |
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.060
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.059
|
|
|
ovulation cycle process
|
GO:0022602 |
2 |
0.059
|
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.059
|
Human Zebrafish Mouse |
|
mitochondrial transport
|
GO:0006839 |
2 |
0.059
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.058
|
Human Zebrafish |
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.058
|
|
|
response to hypoxia
|
GO:0001666 |
25 |
0.057
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.057
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.057
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.057
|
Worm |
|
negative regulation of protein transport
|
GO:0051224 |
3 |
0.056
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
86 |
0.055
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.055
|
|
|
organelle fission
|
GO:0048285 |
23 |
0.055
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
22 |
0.055
|
Zebrafish |
|
regulation of muscle contraction
|
GO:0006937 |
3 |
0.054
|
|
|
mitotic nuclear division
|
GO:0007067 |
18 |
0.054
|
|
|
cellular catabolic process
|
GO:0044248 |
27 |
0.053
|
Worm |
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.053
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.053
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.052
|
Worm |
|
camera type eye development
|
GO:0043010 |
222 |
0.052
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
4 |
0.051
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
27 |
0.051
|
Worm |
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.051
|
|
|
nuclear division
|
GO:0000280 |
23 |
0.051
|
|
|
peptide transport
|
GO:0015833 |
1 |
0.051
|
|
|
aging
|
GO:0007568 |
2 |
0.050
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.050
|
Human Zebrafish Mouse |
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.050
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.050
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.050
|
Human Zebrafish Mouse Worm |
|
neuron neuron synaptic transmission
|
GO:0007270 |
1 |
0.049
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.049
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
17 |
0.048
|
Worm |
|
anatomical structure homeostasis
|
GO:0060249 |
36 |
0.048
|
Zebrafish |
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.048
|
Worm |
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.048
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
21 |
0.048
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
2 |
0.048
|
Human Mouse |
|
mitochondrion morphogenesis
|
GO:0070584 |
2 |
0.048
|
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.047
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.047
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
27 |
0.046
|
Worm |
|
biosynthetic process
|
GO:0009058 |
294 |
0.046
|
|
|
cellular component disassembly
|
GO:0022411 |
1 |
0.045
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.045
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.045
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.045
|
Worm |
|
response to decreased oxygen levels
|
GO:0036293 |
25 |
0.045
|
|
|
regulation of cell cycle process
|
GO:0010564 |
20 |
0.044
|
|
|
growth
|
GO:0040007 |
174 |
0.044
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
2 |
0.044
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
3 |
0.044
|
|
|
disruption of cells of other organism
|
GO:0044364 |
1 |
0.044
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.043
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
2 |
0.043
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.043
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.043
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.043
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
10 |
0.043
|
Zebrafish |
|
homeostatic process
|
GO:0042592 |
142 |
0.042
|
Zebrafish |
|
regulation of gene expression
|
GO:0010468 |
265 |
0.042
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.042
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.041
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.041
|
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.040
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
29 |
0.040
|
Zebrafish |
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.040
|
|
|
cell migration
|
GO:0016477 |
237 |
0.040
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.040
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.040
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.040
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.040
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.039
|
|
|
cognition
|
GO:0050890 |
1 |
0.039
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
10 |
0.039
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.039
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
10 |
0.039
|
Human Zebrafish |
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.038
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.038
|
Worm |
|
tube morphogenesis
|
GO:0035239 |
349 |
0.038
|
|
|
regulation of membrane potential
|
GO:0042391 |
23 |
0.038
|
|
|
regulation of cell division
|
GO:0051302 |
12 |
0.038
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
4 |
0.038
|
|
|
peptide metabolic process
|
GO:0006518 |
1 |
0.037
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
2 |
0.037
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
27 |
0.037
|
Worm |
|
long chain fatty acid metabolic process
|
GO:0001676 |
1 |
0.037
|
|
|
response to nutrient
|
GO:0007584 |
3 |
0.037
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.037
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.037
|
|
|
regulation of organelle organization
|
GO:0033043 |
29 |
0.037
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.036
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.036
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
2 |
0.036
|
|
|
cellular response to radiation
|
GO:0071478 |
4 |
0.036
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.035
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.035
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.035
|
Worm |
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.035
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.035
|
Human Mouse |
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.035
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.035
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
10 |
0.034
|
Zebrafish |
|
response to oxygen levels
|
GO:0070482 |
25 |
0.034
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.034
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.034
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.034
|
Worm |
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.034
|
|
|
single organism cellular localization
|
GO:1902580 |
46 |
0.034
|
|
|
brain development
|
GO:0007420 |
293 |
0.034
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
1 |
0.034
|
|
|
system process
|
GO:0003008 |
185 |
0.034
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
2 |
0.034
|
|
|
catabolic process
|
GO:0009056 |
32 |
0.033
|
Worm |
|
purine nucleotide metabolic process
|
GO:0006163 |
27 |
0.033
|
Worm |
|
neuron death
|
GO:0070997 |
21 |
0.033
|
Human Mouse |
|
metal ion transport
|
GO:0030001 |
58 |
0.033
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
10 |
0.032
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.032
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.032
|
Human Zebrafish Mouse |
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.032
|
Human Zebrafish Mouse |
|
cytokinesis
|
GO:0000910 |
3 |
0.032
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
9 |
0.032
|
Worm |
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.032
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.032
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.032
|
|
|
regulation of blood pressure
|
GO:0008217 |
1 |
0.031
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.031
|
Human Zebrafish |
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.031
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
2 |
0.031
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.031
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.031
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
45 |
0.030
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.030
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
2 |
0.030
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
0 |
0.030
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.030
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
3 |
0.030
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.030
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.030
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.030
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.029
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
10 |
0.029
|
Zebrafish |
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.029
|
Worm |
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.029
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.029
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.029
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.028
|
Worm |
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.028
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.028
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.028
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.028
|
|
|
cell motility
|
GO:0048870 |
244 |
0.028
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.028
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
3 |
0.028
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.028
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
4 |
0.028
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.027
|
|
|
response to hormone
|
GO:0009725 |
48 |
0.027
|
|
|
response to lipid
|
GO:0033993 |
60 |
0.027
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
25 |
0.027
|
|
|
response to virus
|
GO:0009615 |
21 |
0.027
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.027
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
17 |
0.027
|
Human Mouse |
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.027
|
Worm |
|
meiosis i
|
GO:0007127 |
1 |
0.027
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.026
|
|
|
larval development
|
GO:0002164 |
2 |
0.026
|
|
|
locomotion
|
GO:0040011 |
313 |
0.026
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.026
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
0 |
0.026
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
4 |
0.026
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
6 |
0.026
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
2 |
0.026
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.026
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.026
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.026
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.026
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.026
|
|
|
response to methylmercury
|
GO:0051597 |
11 |
0.025
|
Zebrafish |
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.025
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
2 |
0.025
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.025
|
Human Mouse |
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
1 |
0.025
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.025
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.025
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.025
|
Human Mouse |
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.025
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.025
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
10 |
0.025
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.025
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.025
|
|
|
negative regulation of molecular function
|
GO:0044092 |
23 |
0.025
|
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.025
|
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.025
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.024
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.024
|
Worm |
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.024
|
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.024
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.024
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.024
|
|
|
regeneration
|
GO:0031099 |
91 |
0.024
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.024
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
16 |
0.024
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.024
|
|
|
post embryonic morphogenesis
|
GO:0009886 |
4 |
0.024
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.024
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.023
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
1 |
0.023
|
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.023
|
|
|
immune system process
|
GO:0002376 |
241 |
0.023
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
2 |
0.023
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.023
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.022
|
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.022
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.022
|
|
|
response to bacterium
|
GO:0009617 |
58 |
0.022
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.022
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
1 |
0.022
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.022
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.022
|
|
|
regulation of blood vessel size
|
GO:0050880 |
2 |
0.022
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.022
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.022
|
|
|
regulation of ion transport
|
GO:0043269 |
22 |
0.022
|
|
|
response to nitrogen compound
|
GO:1901698 |
19 |
0.022
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.022
|
|
|
positive regulation of cell killing
|
GO:0031343 |
2 |
0.021
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
28 |
0.021
|
Worm |
|
protein complex disassembly
|
GO:0043241 |
1 |
0.021
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.021
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
2 |
0.021
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
3 |
0.021
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.021
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.021
|
|
|
regionalization
|
GO:0003002 |
274 |
0.021
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
2 |
0.021
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
3 |
0.020
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
3 |
0.020
|
|
|
notch signaling pathway
|
GO:0007219 |
35 |
0.020
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.020
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
1 |
0.020
|
|
|
viral process
|
GO:0016032 |
1 |
0.020
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.020
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
4 |
0.020
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.020
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.020
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.020
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.020
|
|
|
membrane fusion
|
GO:0061025 |
2 |
0.020
|
Worm |
|
regulation of transport
|
GO:0051049 |
45 |
0.020
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.020
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.020
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
4 |
0.020
|
|
|
developmental programmed cell death
|
GO:0010623 |
4 |
0.020
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.019
|
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.019
|
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.019
|
|
|
regulation of transcription from rna polymerase ii promoter in response to oxidative stress
|
GO:0043619 |
0 |
0.019
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
2 |
0.019
|
|
|
tissue homeostasis
|
GO:0001894 |
25 |
0.019
|
Zebrafish |
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.019
|
|
|
intracellular transport
|
GO:0046907 |
32 |
0.019
|
|
|
interaction with host
|
GO:0051701 |
4 |
0.019
|
|
|
regulation of heart growth
|
GO:0060420 |
2 |
0.019
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
10 |
0.019
|
Worm |
|
regulation of hormone secretion
|
GO:0046883 |
2 |
0.019
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
1 |
0.019
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
61 |
0.019
|
Worm |
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.019
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
45 |
0.019
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.019
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
2 |
0.018
|
|
|
killing of cells in other organism involved in symbiotic interaction
|
GO:0051883 |
1 |
0.018
|
|
|
ion transport
|
GO:0006811 |
114 |
0.018
|
|
|
organophosphate metabolic process
|
GO:0019637 |
37 |
0.018
|
Worm |
|
reproduction
|
GO:0000003 |
40 |
0.018
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.018
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.018
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
1 |
0.018
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.018
|
|
|
regulation of mitosis
|
GO:0007088 |
9 |
0.018
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.018
|
Worm |
|
female gonad development
|
GO:0008585 |
4 |
0.018
|
|
|
nitrogen compound transport
|
GO:0071705 |
23 |
0.018
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
9 |
0.018
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
22 |
0.018
|
Human Mouse |
|
cell proliferation
|
GO:0008283 |
80 |
0.017
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.017
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
12 |
0.017
|
Human Zebrafish Mouse |
|
cation transport
|
GO:0006812 |
81 |
0.017
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
2 |
0.017
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.017
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
4 |
0.017
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
2 |
0.017
|
|
|
protein dephosphorylation
|
GO:0006470 |
3 |
0.017
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.017
|
|
|
endocrine system development
|
GO:0035270 |
65 |
0.017
|
Zebrafish |
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.017
|
|
|
response to light stimulus
|
GO:0009416 |
46 |
0.017
|
|
|
organ regeneration
|
GO:0031100 |
1 |
0.017
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
17 |
0.017
|
Worm |
|
cellular response to hormone stimulus
|
GO:0032870 |
39 |
0.017
|
|
|
eye development
|
GO:0001654 |
277 |
0.017
|
|
|
convergent extension
|
GO:0060026 |
118 |
0.017
|
|
|
telomere maintenance
|
GO:0000723 |
1 |
0.017
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.016
|
Zebrafish |
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.016
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.016
|
Worm |
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
90 |
0.016
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
2 |
0.016
|
|
|
response to amino acid
|
GO:0043200 |
2 |
0.016
|
|
|
protein polyubiquitination
|
GO:0000209 |
4 |
0.016
|
|
|
regulation of dendrite development
|
GO:0050773 |
3 |
0.016
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.016
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
2 |
0.016
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.016
|
|
|
regulation of wound healing
|
GO:0061041 |
2 |
0.016
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
3 |
0.016
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
2 |
0.016
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.016
|
|
|
regulation of protein processing
|
GO:0070613 |
10 |
0.016
|
|
|
ovarian follicle development
|
GO:0001541 |
2 |
0.016
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.016
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.016
|
|
|
regulation of lipid transport
|
GO:0032368 |
4 |
0.016
|
|
|
single organism intracellular transport
|
GO:1902582 |
25 |
0.016
|
|
|
response to uv
|
GO:0009411 |
3 |
0.015
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.015
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
2 |
0.015
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
1 |
0.015
|
|
|
dna metabolic process
|
GO:0006259 |
27 |
0.015
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
4 |
0.015
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
2 |
0.015
|
|
|
cellular amide metabolic process
|
GO:0043603 |
4 |
0.015
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.015
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.015
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
2 |
0.015
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.015
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.015
|
Zebrafish Worm |
|
neuron apoptotic process
|
GO:0051402 |
20 |
0.015
|
Human Mouse |
|
negative regulation of map kinase activity
|
GO:0043407 |
2 |
0.015
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.015
|
Worm |
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.015
|
|
|
response to glucose
|
GO:0009749 |
3 |
0.015
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
3 |
0.015
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
48 |
0.015
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.015
|
|
|
biomineral tissue development
|
GO:0031214 |
13 |
0.015
|
|
|
regulation of sterol transport
|
GO:0032371 |
3 |
0.014
|
|