Danio rerio

101 known processes

mcl1b

myeloid cell leukemia sequence 1b

(Aliases: zgc:109763)

mcl1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular process GO:0048523 283 0.640
negative regulation of mitosis GO:0045839 3 0.564
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.478
Human Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.459
Zebrafish
negative regulation of nuclear division GO:0051784 3 0.450
response to stress GO:0006950 263 0.402
Human Mouse
protein localization to nucleus GO:0034504 3 0.387
regulation of signaling GO:0023051 235 0.354
Human Zebrafish Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.351
Worm
single organism membrane fusion GO:0044801 2 0.345
Worm
regulation of gtp catabolic process GO:0033124 2 0.315
Worm
negative regulation of biological process GO:0048519 304 0.309
regulation of cysteine type endopeptidase activity GO:2000116 21 0.300
positive regulation of cellular catabolic process GO:0031331 3 0.290
Worm
positive regulation of biological process GO:0048518 253 0.288
Human Zebrafish Mouse Worm
positive regulation of catabolic process GO:0009896 4 0.276
Worm
guanosine containing compound catabolic process GO:1901069 2 0.272
Worm
regulation of metal ion transport GO:0010959 4 0.268
gtp metabolic process GO:0046039 4 0.261
Worm
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.261
Human
establishment of protein localization to organelle GO:0072594 4 0.251
organelle fusion GO:0048284 3 0.250
Worm
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.245
positive regulation of neuron apoptotic process GO:0043525 1 0.244
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.242
regulation of nucleotide catabolic process GO:0030811 2 0.241
Worm
regulation of metabolic process GO:0019222 359 0.240
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.233
Human Mouse
mitochondrion organization GO:0007005 4 0.225
Mouse Worm
nucleocytoplasmic transport GO:0006913 4 0.219
regulation of nitrogen compound metabolic process GO:0051171 251 0.216
Worm
organelle organization GO:0006996 227 0.209
regulation of response to stimulus GO:0048583 269 0.204
Human Zebrafish Mouse
regulation of peptidase activity GO:0052547 23 0.202
regulation of apoptotic process GO:0042981 98 0.201
single organism nuclear import GO:1902593 3 0.200
nuclear import GO:0051170 3 0.197
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.196
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.195
Human
signal transduction GO:0007165 455 0.190
Human Zebrafish Mouse
negative regulation of gene expression GO:0010629 65 0.190
nuclear transport GO:0051169 4 0.189
protein import GO:0017038 3 0.185
apoptotic process GO:0006915 116 0.182
positive regulation of gtpase activity GO:0043547 1 0.180
Worm
regulation of cell death GO:0010941 103 0.174
cell death GO:0008219 121 0.173
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.171
Worm
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.169
Zebrafish
gene expression GO:0010467 252 0.159
protein targeting to nucleus GO:0044744 3 0.157
negative regulation of cell communication GO:0010648 96 0.152
Human Zebrafish
response to organic substance GO:0010033 153 0.146
Human Zebrafish
gland development GO:0048732 143 0.144
Zebrafish
regulation of protein catabolic process GO:0042176 1 0.140
protein import into nucleus GO:0006606 3 0.136
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.132
positive regulation of neuron death GO:1901216 1 0.131
Human Mouse
negative regulation of cell division GO:0051782 4 0.128
regulation of mitochondrion organization GO:0010821 1 0.127
Worm
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.127
Human
cell death in response to oxidative stress GO:0036473 2 0.127
Human Mouse
gtp catabolic process GO:0006184 2 0.127
Worm
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.125
Worm
organonitrogen compound metabolic process GO:1901564 74 0.124
Worm
positive regulation of transport GO:0051050 2 0.122
negative regulation of protein maturation GO:1903318 10 0.121
regulation of response to oxidative stress GO:1902882 2 0.121
Human Mouse
signal transduction in absence of ligand GO:0038034 1 0.121
Human Mouse
response to transition metal nanoparticle GO:1990267 28 0.120
Zebrafish
regulation of protein localization to nucleus GO:1900180 2 0.119
regulation of protein transport GO:0051223 3 0.118
regulation of macromolecule metabolic process GO:0060255 317 0.115
regulation of cell cycle GO:0051726 52 0.115
negative regulation of signaling GO:0023057 96 0.114
Human Zebrafish
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.114
Human Mouse
small molecule metabolic process GO:0044281 77 0.113
Worm
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.109
Zebrafish
regulation of developmental process GO:0050793 247 0.107
Worm
single organism transport GO:0044765 206 0.107
embryo development ending in birth or egg hatching GO:0009792 271 0.105
regulation of protein maturation GO:1903317 10 0.104
response to cadmium ion GO:0046686 14 0.104
Zebrafish
negative regulation of mitotic cell cycle GO:0045930 11 0.104
modulation by virus of host morphology or physiology GO:0019048 1 0.104
response to glucocorticoid GO:0051384 1 0.103
regulation of gtpase activity GO:0043087 2 0.102
Worm
negative regulation of cell cycle GO:0045786 14 0.102
thyroid gland development GO:0030878 12 0.100
Zebrafish
regulation of signal transduction GO:0009966 225 0.099
Human Zebrafish Mouse
cellular response to chemical stimulus GO:0070887 157 0.099
Human Mouse
response to chemical GO:0042221 320 0.098
Human Zebrafish Mouse
immune system development GO:0002520 191 0.098
response to drug GO:0042493 3 0.095
regulation of proteolysis GO:0030162 24 0.094
macromolecule biosynthetic process GO:0009059 227 0.093
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.093
Human
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.093
Human
cell surface receptor signaling pathway GO:0007166 325 0.093
Human Mouse
negative regulation of hydrolase activity GO:0051346 10 0.092
regulation of nucleoside metabolic process GO:0009118 2 0.092
Worm
regulation of primary metabolic process GO:0080090 311 0.091
regulation of nucleic acid templated transcription GO:1903506 213 0.090
proteolysis GO:0006508 38 0.089
death GO:0016265 121 0.088
positive regulation of nucleotide catabolic process GO:0030813 1 0.087
Worm
cellular response to hypoxia GO:0071456 1 0.086
extrinsic apoptotic signaling pathway GO:0097191 3 0.086
Human Mouse
cellular response to oxygen levels GO:0071453 1 0.085
regulation of cellular response to oxidative stress GO:1900407 2 0.084
Human Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.084
negative regulation of protein processing GO:0010955 10 0.083
positive regulation of apoptotic signaling pathway GO:2001235 1 0.082
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.081
regulation of biological quality GO:0065008 263 0.080
Zebrafish
fertilization GO:0009566 3 0.080
regulation of endopeptidase activity GO:0052548 23 0.079
response to inorganic substance GO:0010035 38 0.077
Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.076
programmed cell death GO:0012501 119 0.076
regulation of establishment of protein localization GO:0070201 4 0.074
regulation of intracellular signal transduction GO:1902531 57 0.072
Human Zebrafish Mouse
protein complex localization GO:0031503 1 0.072
cellular response to stress GO:0033554 62 0.071
Human Mouse
regulation of cytoplasmic transport GO:1903649 4 0.069
regulation of protein metabolic process GO:0051246 56 0.069
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.069
response to metal ion GO:0010038 34 0.068
Zebrafish
cellular response to light stimulus GO:0071482 4 0.066
nucleobase containing compound biosynthetic process GO:0034654 205 0.066
transport GO:0006810 220 0.066
amide transport GO:0042886 12 0.065
positive regulation of cell death GO:0010942 29 0.064
Human Zebrafish Mouse
meiotic nuclear division GO:0007126 4 0.064
regulation of programmed cell death GO:0043067 101 0.063
multi organism cellular process GO:0044764 2 0.063
nucleobase containing small molecule metabolic process GO:0055086 32 0.063
Worm
positive regulation of hydrolase activity GO:0051345 13 0.061
Zebrafish Worm
cellular localization GO:0051641 97 0.061
positive regulation of nucleoside metabolic process GO:0045979 1 0.061
Worm
cellular response to decreased oxygen levels GO:0036294 1 0.060
organic cyclic compound metabolic process GO:1901360 301 0.060
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.060
Worm
cellular response to external stimulus GO:0071496 2 0.060
chordate embryonic development GO:0043009 271 0.059
ovulation cycle process GO:0022602 2 0.059
regulation of cell communication GO:0010646 232 0.059
Human Zebrafish Mouse
mitochondrial transport GO:0006839 2 0.059
negative regulation of response to stimulus GO:0048585 104 0.058
Human Zebrafish
regulation of nucleocytoplasmic transport GO:0046822 2 0.058
response to hypoxia GO:0001666 25 0.057
retina development in camera type eye GO:0060041 146 0.057
carboxylic acid metabolic process GO:0019752 22 0.057
regulation of purine nucleotide catabolic process GO:0033121 2 0.057
Worm
negative regulation of protein transport GO:0051224 3 0.056
developmental growth involved in morphogenesis GO:0060560 86 0.055
cellular component movement GO:0006928 335 0.055
organelle fission GO:0048285 23 0.055
negative regulation of intracellular signal transduction GO:1902532 22 0.055
Zebrafish
regulation of muscle contraction GO:0006937 3 0.054
mitotic nuclear division GO:0007067 18 0.054
cellular catabolic process GO:0044248 27 0.053
Worm
regulation of cytokine production GO:0001817 3 0.053
ameboidal type cell migration GO:0001667 143 0.053
single organism metabolic process GO:0044710 217 0.052
Worm
camera type eye development GO:0043010 222 0.052
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.051
purine ribonucleotide metabolic process GO:0009150 27 0.051
Worm
aromatic compound biosynthetic process GO:0019438 217 0.051
nuclear division GO:0000280 23 0.051
peptide transport GO:0015833 1 0.051
aging GO:0007568 2 0.050
positive regulation of apoptotic process GO:0043065 29 0.050
Human Zebrafish Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.050
multicellular organism growth GO:0035264 4 0.050
positive regulation of cellular process GO:0048522 201 0.050
Human Zebrafish Mouse Worm
neuron neuron synaptic transmission GO:0007270 1 0.049
regulation of multicellular organismal development GO:2000026 223 0.049
regulation of nucleotide metabolic process GO:0006140 17 0.048
Worm
anatomical structure homeostasis GO:0060249 36 0.048
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.048
Worm
cellular macromolecule metabolic process GO:0044260 391 0.048
negative regulation of catalytic activity GO:0043086 21 0.048
regulation of oxidative stress induced cell death GO:1903201 2 0.048
Human Mouse
mitochondrion morphogenesis GO:0070584 2 0.048
cellular protein catabolic process GO:0044257 4 0.047
response to hexose GO:0009746 3 0.047
ribose phosphate metabolic process GO:0019693 27 0.046
Worm
biosynthetic process GO:0009058 294 0.046
cellular component disassembly GO:0022411 1 0.045
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.045
regulation of protein targeting GO:1903533 2 0.045
heterocycle metabolic process GO:0046483 290 0.045
Worm
response to decreased oxygen levels GO:0036293 25 0.045
regulation of cell cycle process GO:0010564 20 0.044
growth GO:0040007 174 0.044
regulation of calcium ion transport GO:0051924 2 0.044
positive regulation of multi organism process GO:0043902 3 0.044
disruption of cells of other organism GO:0044364 1 0.044
response to biotic stimulus GO:0009607 97 0.043
negative regulation of cytoplasmic transport GO:1903650 2 0.043
modification by symbiont of host morphology or physiology GO:0044003 4 0.043
stem cell proliferation GO:0072089 4 0.043
blood vessel development GO:0001568 246 0.043
positive regulation of proteolysis GO:0045862 10 0.043
Zebrafish
homeostatic process GO:0042592 142 0.042
Zebrafish
regulation of gene expression GO:0010468 265 0.042
regulation of intracellular protein transport GO:0033157 3 0.042
single organism localization GO:1902578 225 0.041
negative regulation of metabolic process GO:0009892 86 0.041
regulation of organ growth GO:0046620 3 0.040
multicellular organismal homeostasis GO:0048871 29 0.040
Zebrafish
regulation of epithelial cell proliferation GO:0050678 3 0.040
cell migration GO:0016477 237 0.040
response to organic cyclic compound GO:0014070 51 0.040
macromolecule modification GO:0043412 111 0.040
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.040
ubiquitin dependent protein catabolic process GO:0006511 3 0.040
transcription from rna polymerase ii promoter GO:0006366 80 0.039
cognition GO:0050890 1 0.039
negative regulation of endopeptidase activity GO:0010951 10 0.039
negative regulation of programmed cell death GO:0043069 58 0.039
negative regulation of apoptotic signaling pathway GO:2001234 10 0.039
Human Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
Worm
tube morphogenesis GO:0035239 349 0.038
regulation of membrane potential GO:0042391 23 0.038
regulation of cell division GO:0051302 12 0.038
modification of morphology or physiology of other organism GO:0035821 4 0.038
peptide metabolic process GO:0006518 1 0.037
negative regulation of protein import into nucleus GO:0042308 2 0.037
ribonucleotide metabolic process GO:0009259 27 0.037
Worm
long chain fatty acid metabolic process GO:0001676 1 0.037
response to nutrient GO:0007584 3 0.037
transcription dna templated GO:0006351 181 0.037
digestive system development GO:0055123 289 0.037
regulation of organelle organization GO:0033043 29 0.037
protein metabolic process GO:0019538 183 0.036
negative regulation of cellular biosynthetic process GO:0031327 55 0.036
positive regulation of protein complex assembly GO:0031334 2 0.036
cellular response to radiation GO:0071478 4 0.036
maintenance of location GO:0051235 4 0.035
developmental growth GO:0048589 166 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.035
Worm
negative regulation of biosynthetic process GO:0009890 55 0.035
cellular response to dna damage stimulus GO:0006974 24 0.035
Human Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.035
hematopoietic or lymphoid organ development GO:0048534 191 0.035
positive regulation of peptidase activity GO:0010952 10 0.034
Zebrafish
response to oxygen levels GO:0070482 25 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
cellular protein metabolic process GO:0044267 129 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.034
single organism cellular localization GO:1902580 46 0.034
brain development GO:0007420 293 0.034
regulation of synaptic plasticity GO:0048167 1 0.034
system process GO:0003008 185 0.034
negative regulation of secretion by cell GO:1903531 2 0.034
catabolic process GO:0009056 32 0.033
Worm
purine nucleotide metabolic process GO:0006163 27 0.033
Worm
neuron death GO:0070997 21 0.033
Human Mouse
metal ion transport GO:0030001 58 0.033
negative regulation of proteolysis GO:0045861 10 0.032
peptidyl serine modification GO:0018209 2 0.032
positive regulation of programmed cell death GO:0043068 29 0.032
Human Zebrafish Mouse
intracellular signal transduction GO:0035556 85 0.032
Human Zebrafish Mouse
cytokinesis GO:0000910 3 0.032
positive regulation of nucleotide metabolic process GO:0045981 9 0.032
Worm
negative regulation of macromolecule metabolic process GO:0010605 76 0.032
g1 s transition of mitotic cell cycle GO:0000082 1 0.032
blood vessel morphogenesis GO:0048514 216 0.032
regulation of blood pressure GO:0008217 1 0.031
negative regulation of signal transduction GO:0009968 94 0.031
Human Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
regulation of sodium ion transport GO:0002028 2 0.031
embryonic organ development GO:0048568 381 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
negative regulation of rna biosynthetic process GO:1902679 45 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.030
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.030
negative regulation of rna metabolic process GO:0051253 48 0.030
negative regulation of intracellular protein transport GO:0090317 3 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
cellular response to nutrient levels GO:0031669 2 0.030
cellular response to starvation GO:0009267 1 0.030
regulation of molecular function GO:0065009 70 0.029
positive regulation of endopeptidase activity GO:0010950 10 0.029
Zebrafish
regulation of phosphate metabolic process GO:0019220 43 0.029
Worm
response to oxygen containing compound GO:1901700 55 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
phagocytosis GO:0006909 3 0.029
phosphorus metabolic process GO:0006793 109 0.028
Worm
regulation of protein complex assembly GO:0043254 3 0.028
response to radiation GO:0009314 51 0.028
cellular response to endogenous stimulus GO:0071495 68 0.028
adult behavior GO:0030534 2 0.028
cell motility GO:0048870 244 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
cellular response to lipopolysaccharide GO:0071222 3 0.028
rna biosynthetic process GO:0032774 181 0.028
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.028
regulation of binding GO:0051098 3 0.027
response to hormone GO:0009725 48 0.027
response to lipid GO:0033993 60 0.027
regulation of mitotic cell cycle GO:0007346 25 0.027
response to virus GO:0009615 21 0.027
regulation of biosynthetic process GO:0009889 250 0.027
regulation of neuron apoptotic process GO:0043523 17 0.027
Human Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.027
Worm
meiosis i GO:0007127 1 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.026
larval development GO:0002164 2 0.026
locomotion GO:0040011 313 0.026
localization of cell GO:0051674 244 0.026
regulation of dna templated transcription in response to stress GO:0043620 0 0.026
negative regulation of organelle organization GO:0010639 4 0.026
reactive oxygen species metabolic process GO:0072593 6 0.026
apoptotic process involved in morphogenesis GO:0060561 2 0.026
establishment of localization GO:0051234 244 0.026
negative regulation of kinase activity GO:0033673 4 0.026
amine metabolic process GO:0009308 2 0.026
nucleic acid metabolic process GO:0090304 244 0.026
organic acid metabolic process GO:0006082 31 0.026
response to methylmercury GO:0051597 11 0.025
Zebrafish
response to abiotic stimulus GO:0009628 122 0.025
positive regulation of blood circulation GO:1903524 2 0.025
positive regulation of signal transduction GO:0009967 56 0.025
Human Mouse
reactive oxygen species biosynthetic process GO:1903409 1 0.025
regulation of rna metabolic process GO:0051252 224 0.025
negative regulation of cell death GO:0060548 60 0.025
positive regulation of signaling GO:0023056 56 0.025
Human Mouse
regulation of cellular protein catabolic process GO:1903362 1 0.025
cellular response to organic substance GO:0071310 105 0.025
negative regulation of peptidase activity GO:0010466 10 0.025
cellular biosynthetic process GO:0044249 286 0.025
generation of neurons GO:0048699 385 0.025
negative regulation of molecular function GO:0044092 23 0.025
response to corticosteroid GO:0031960 1 0.025
response to carbohydrate GO:0009743 3 0.025
peptidyl serine phosphorylation GO:0018105 1 0.024
positive regulation of developmental process GO:0051094 50 0.024
Worm
regulation of carbohydrate metabolic process GO:0006109 4 0.024
female sex differentiation GO:0046660 4 0.024
nucleic acid templated transcription GO:0097659 181 0.024
angiogenesis GO:0001525 158 0.024
regeneration GO:0031099 91 0.024
sensory organ development GO:0007423 393 0.024
negative regulation of cellular component organization GO:0051129 16 0.024
vasculature development GO:0001944 278 0.024
post embryonic morphogenesis GO:0009886 4 0.024
apoptotic process involved in development GO:1902742 2 0.024
morphogenesis of an epithelium GO:0002009 333 0.023
positive regulation of epithelial cell proliferation GO:0050679 1 0.023
single organism biosynthetic process GO:0044711 71 0.023
immune system process GO:0002376 241 0.023
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.023
regulation of localization GO:0032879 104 0.023
regulation of rna biosynthetic process GO:2001141 213 0.022
regulation of tube size GO:0035150 2 0.022
positive regulation of cell cycle GO:0045787 3 0.022
response to bacterium GO:0009617 58 0.022
response to other organism GO:0051707 97 0.022
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
organic substance transport GO:0071702 58 0.022
regulation of blood vessel size GO:0050880 2 0.022
neurological system process GO:0050877 62 0.022
positive regulation of dna metabolic process GO:0051054 1 0.022
regulation of ion transport GO:0043269 22 0.022
response to nitrogen compound GO:1901698 19 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.022
positive regulation of cell killing GO:0031343 2 0.021
nucleoside phosphate metabolic process GO:0006753 28 0.021
Worm
protein complex disassembly GO:0043241 1 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
multicellular organismal metabolic process GO:0044236 2 0.021
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cell cycle process GO:0022402 53 0.021
regionalization GO:0003002 274 0.021
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.021
positive regulation of immune effector process GO:0002699 3 0.020
cytosolic calcium ion transport GO:0060401 3 0.020
notch signaling pathway GO:0007219 35 0.020
myeloid cell differentiation GO:0030099 86 0.020
negative regulation of myeloid cell differentiation GO:0045638 1 0.020
viral process GO:0016032 1 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
response to endogenous stimulus GO:0009719 83 0.020
digestive tract development GO:0048565 265 0.020
membrane fusion GO:0061025 2 0.020
Worm
regulation of transport GO:0051049 45 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
skeletal system development GO:0001501 181 0.020
toll like receptor signaling pathway GO:0002224 4 0.020
developmental programmed cell death GO:0010623 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.019
energy reserve metabolic process GO:0006112 2 0.019
embryonic skeletal system development GO:0048706 97 0.019
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
tissue homeostasis GO:0001894 25 0.019
Zebrafish
meiotic cell cycle process GO:1903046 3 0.019
intracellular transport GO:0046907 32 0.019
interaction with host GO:0051701 4 0.019
regulation of heart growth GO:0060420 2 0.019
purine ribonucleoside metabolic process GO:0046128 10 0.019
Worm
regulation of hormone secretion GO:0046883 2 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.019
Worm
cytoskeleton organization GO:0007010 96 0.019
negative regulation of nucleic acid templated transcription GO:1903507 45 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of response to biotic stimulus GO:0002831 2 0.018
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.018
ion transport GO:0006811 114 0.018
organophosphate metabolic process GO:0019637 37 0.018
Worm
reproduction GO:0000003 40 0.018
regulation of transcription dna templated GO:0006355 213 0.018
hemopoiesis GO:0030097 183 0.018
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.018
organic substance biosynthetic process GO:1901576 289 0.018
regulation of mitosis GO:0007088 9 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
Worm
female gonad development GO:0008585 4 0.018
nitrogen compound transport GO:0071705 23 0.018
negative regulation of cell cycle process GO:0010948 9 0.018
cell type specific apoptotic process GO:0097285 22 0.018
Human Mouse
cell proliferation GO:0008283 80 0.017
lipid storage GO:0019915 1 0.017
regulation of apoptotic signaling pathway GO:2001233 12 0.017
Human Zebrafish Mouse
cation transport GO:0006812 81 0.017
cellular response to unfolded protein GO:0034620 2 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
fatty acid biosynthetic process GO:0006633 4 0.017
response to topologically incorrect protein GO:0035966 2 0.017
protein dephosphorylation GO:0006470 3 0.017
cell cycle GO:0007049 93 0.017
endocrine system development GO:0035270 65 0.017
Zebrafish
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
response to light stimulus GO:0009416 46 0.017
organ regeneration GO:0031100 1 0.017
regulation of purine nucleotide metabolic process GO:1900542 17 0.017
Worm
cellular response to hormone stimulus GO:0032870 39 0.017
eye development GO:0001654 277 0.017
convergent extension GO:0060026 118 0.017
telomere maintenance GO:0000723 1 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
Zebrafish
mitotic cell cycle GO:0000278 64 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.016
negative regulation of hormone secretion GO:0046888 2 0.016
response to amino acid GO:0043200 2 0.016
protein polyubiquitination GO:0000209 4 0.016
regulation of dendrite development GO:0050773 3 0.016
oxoacid metabolic process GO:0043436 31 0.016
negative regulation of response to cytokine stimulus GO:0060761 2 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
regulation of wound healing GO:0061041 2 0.016
negative regulation of response to dna damage stimulus GO:2001021 3 0.016
er nucleus signaling pathway GO:0006984 2 0.016
positive regulation of cytokine production GO:0001819 2 0.016
regulation of protein processing GO:0070613 10 0.016
ovarian follicle development GO:0001541 2 0.016
chemosensory behavior GO:0007635 1 0.016
camera type eye morphogenesis GO:0048593 108 0.016
regulation of lipid transport GO:0032368 4 0.016
single organism intracellular transport GO:1902582 25 0.016
response to uv GO:0009411 3 0.015
digestive tract morphogenesis GO:0048546 231 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
carbohydrate homeostasis GO:0033500 1 0.015
dna metabolic process GO:0006259 27 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
cellular amide metabolic process GO:0043603 4 0.015
response to external stimulus GO:0009605 264 0.015
phosphorylation GO:0016310 69 0.015
negative regulation of protein localization to nucleus GO:1900181 2 0.015
hepaticobiliary system development GO:0061008 98 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Zebrafish Worm
neuron apoptotic process GO:0051402 20 0.015
Human Mouse
negative regulation of map kinase activity GO:0043407 2 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.015
response to glucose GO:0009749 3 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
biomineral tissue development GO:0031214 13 0.015
regulation of sterol transport GO:0032371 3 0.014

mcl1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.028
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.028