Danio rerio

0 known processes

rap2b

RAP2B, member of RAS oncogene family

(Aliases: zgc:55550,wu:fi34c06,MGC55550)

rap2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.084
regulation of rna biosynthetic process GO:2001141 213 0.082
rna biosynthetic process GO:0032774 181 0.077
cellular protein catabolic process GO:0044257 4 0.076
hormone secretion GO:0046879 2 0.074
programmed cell death GO:0012501 119 0.073
cellular ketone metabolic process GO:0042180 11 0.073
macromolecule biosynthetic process GO:0009059 227 0.073
transport GO:0006810 220 0.073
nitrogen compound metabolic process GO:0006807 319 0.073
Yeast
rna metabolic process GO:0016070 219 0.072
heterocycle metabolic process GO:0046483 290 0.071
Yeast
cellular nitrogen compound metabolic process GO:0034641 290 0.070
Yeast
aromatic compound biosynthetic process GO:0019438 217 0.067
regulation of rna metabolic process GO:0051252 224 0.065
regulation of cellular metabolic process GO:0031323 320 0.061
single organism transport GO:0044765 206 0.060
regulation of mrna processing GO:0050684 3 0.060
cellular macromolecule metabolic process GO:0044260 391 0.059
nuclear transport GO:0051169 4 0.059
establishment of localization GO:0051234 244 0.056
nucleic acid templated transcription GO:0097659 181 0.056
regulation of signal transduction GO:0009966 225 0.055
regulation of cellular biosynthetic process GO:0031326 245 0.054
transcription dna templated GO:0006351 181 0.054
regulation of primary metabolic process GO:0080090 311 0.053
cellular biosynthetic process GO:0044249 286 0.053
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.052
cellular aromatic compound metabolic process GO:0006725 295 0.051
Yeast
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.051
cellular component movement GO:0006928 335 0.050
organic cyclic compound metabolic process GO:1901360 301 0.050
Yeast
regulation of nucleic acid templated transcription GO:1903506 213 0.049
regulation of response to stimulus GO:0048583 269 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.048
organic substance biosynthetic process GO:1901576 289 0.048
organelle organization GO:0006996 227 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.046
larval development GO:0002164 2 0.046
adult behavior GO:0030534 2 0.045
regulation of cell communication GO:0010646 232 0.042
positive regulation of cell cycle GO:0045787 3 0.042
vasculature development GO:0001944 278 0.040
regulation of establishment of protein localization GO:0070201 4 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.040
negative regulation of protein kinase activity GO:0006469 4 0.039
regulation of signaling GO:0023051 235 0.038
alternative mrna splicing via spliceosome GO:0000380 1 0.038
amine metabolic process GO:0009308 2 0.038
organism emergence from protective structure GO:0071684 4 0.037
adherens junction organization GO:0034332 4 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
maintenance of location GO:0051235 4 0.037
multicellular organism growth GO:0035264 4 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.037
Yeast
regulation of biosynthetic process GO:0009889 250 0.036
organic cyclic compound biosynthetic process GO:1901362 223 0.036
single organism localization GO:1902578 225 0.036
regulation of gene expression GO:0010468 265 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.035
peptide transport GO:0015833 1 0.035
regulation of metabolic process GO:0019222 359 0.035
regulation of circadian rhythm GO:0042752 4 0.035
hormone transport GO:0009914 2 0.034
regulation of macromolecule metabolic process GO:0060255 317 0.034
response to hexose GO:0009746 3 0.034
response to chemical GO:0042221 320 0.034
regulation of cytoplasmic transport GO:1903649 4 0.034
regulation of cytokine production GO:0001817 3 0.033
aging GO:0007568 2 0.033
locomotion GO:0040011 313 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
response to monosaccharide GO:0034284 3 0.032
negative regulation of cellular process GO:0048523 283 0.032
Fly
chordate embryonic development GO:0043009 271 0.032
regulation of multicellular organismal development GO:2000026 223 0.031
nucleic acid metabolic process GO:0090304 244 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
establishment of protein localization to plasma membrane GO:0090002 1 0.031
modification dependent protein catabolic process GO:0019941 3 0.031
regulation of protein transport GO:0051223 3 0.031
response to carbohydrate GO:0009743 3 0.031
proteasomal protein catabolic process GO:0010498 2 0.030
morphogenesis of an epithelium GO:0002009 333 0.029
regulation of meiotic cell cycle GO:0051445 1 0.029
hemopoiesis GO:0030097 183 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.029
digestive tract development GO:0048565 265 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
negative regulation of kinase activity GO:0033673 4 0.028
fertilization GO:0009566 3 0.027
regulation of mrna splicing via spliceosome GO:0048024 3 0.027
death GO:0016265 121 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
cellular amine metabolic process GO:0044106 2 0.026
positive regulation of biological process GO:0048518 253 0.026
stem cell maintenance GO:0019827 4 0.025
Fly
single organism metabolic process GO:0044710 217 0.025
Yeast
gene expression GO:0010467 252 0.025
apoptotic process GO:0006915 116 0.025
golgi vesicle transport GO:0048193 3 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
sensory organ development GO:0007423 393 0.025
positive regulation of cytokine production GO:0001819 2 0.024
regionalization GO:0003002 274 0.024
localization within membrane GO:0051668 1 0.024
regulation of developmental process GO:0050793 247 0.024
Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
embryonic organ development GO:0048568 381 0.024
cell death GO:0008219 121 0.023
regulation of apoptotic process GO:0042981 98 0.023
regulation of cell death GO:0010941 103 0.023
response to external stimulus GO:0009605 264 0.023
response to topologically incorrect protein GO:0035966 2 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
lateral inhibition GO:0046331 1 0.023
lipid storage GO:0019915 1 0.023
cellular localization GO:0051641 97 0.023
nuclear import GO:0051170 3 0.023
response to glucose GO:0009749 3 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
gtp catabolic process GO:0006184 2 0.022
Yeast
establishment of protein localization to organelle GO:0072594 4 0.022
regulation of inflammatory response GO:0050727 2 0.022
central nervous system development GO:0007417 387 0.021
pronuclear migration GO:0035046 1 0.021
neuroblast proliferation GO:0007405 2 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
positive regulation of response to stimulus GO:0048584 80 0.021
gastrulation GO:0007369 208 0.021
intracellular signal transduction GO:0035556 85 0.021
cytoskeleton dependent cytokinesis GO:0061640 3 0.021
protein localization to plasma membrane GO:0072659 1 0.021
cell migration GO:0016477 237 0.020
negative regulation of biological process GO:0048519 304 0.020
Fly
positive regulation of cell activation GO:0050867 1 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
negative regulation of cytokine production GO:0001818 1 0.020
protein import GO:0017038 3 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
immune system process GO:0002376 241 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.020
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
female sex differentiation GO:0046660 4 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
regulation of oocyte development GO:0060281 3 0.020
response to organic substance GO:0010033 153 0.020
positive regulation of immune effector process GO:0002699 3 0.020
cellular component assembly GO:0022607 170 0.020
regulation of transcription dna templated GO:0006355 213 0.020
regulation of programmed cell death GO:0043067 101 0.020
cellular response to organic substance GO:0071310 105 0.019
phagocytosis GO:0006909 3 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
inositol lipid mediated signaling GO:0048017 2 0.019
tube morphogenesis GO:0035239 349 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
macromolecule localization GO:0033036 54 0.018
positive regulation of catabolic process GO:0009896 4 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
negative regulation of ras protein signal transduction GO:0046580 1 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
membrane fusion GO:0061025 2 0.018
locomotor rhythm GO:0045475 3 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
Yeast
cellular amino acid metabolic process GO:0006520 7 0.018
regulation of binding GO:0051098 3 0.018
protein targeting to nucleus GO:0044744 3 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
developmental growth GO:0048589 166 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.018
organic acid metabolic process GO:0006082 31 0.018
multi organism process GO:0051704 134 0.018
single fertilization GO:0007338 3 0.017
lamellipodium assembly GO:0030032 1 0.017
actin filament polymerization GO:0030041 2 0.017
positive regulation of transport GO:0051050 2 0.017
exocytosis GO:0006887 1 0.017
protein metabolic process GO:0019538 183 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
digestive system development GO:0055123 289 0.017
response to abiotic stimulus GO:0009628 122 0.017
stem cell proliferation GO:0072089 4 0.017
glucose homeostasis GO:0042593 1 0.017
regulation of cell activation GO:0050865 1 0.017
blood vessel morphogenesis GO:0048514 216 0.017
response to stress GO:0006950 263 0.017
Human
protein complex disassembly GO:0043241 1 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
gtp metabolic process GO:0046039 4 0.016
Yeast
single organism organelle organization GO:1902589 199 0.016
oxoacid metabolic process GO:0043436 31 0.016
negative regulation of signaling GO:0023057 96 0.016
cell morphogenesis GO:0000902 289 0.016
immune system development GO:0002520 191 0.016
brain development GO:0007420 293 0.016
nuclear migration GO:0007097 3 0.016
guanosine containing compound catabolic process GO:1901069 2 0.015
Yeast
positive regulation of rna metabolic process GO:0051254 59 0.015
growth GO:0040007 174 0.015
regulation of protein catabolic process GO:0042176 1 0.015
stem cell fate commitment GO:0048865 1 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
cell motility GO:0048870 244 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
anterior posterior pattern specification GO:0009952 152 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
neurotransmitter transport GO:0006836 2 0.015
protein secretion GO:0009306 1 0.015
medulla oblongata development GO:0021550 4 0.015
generation of neurons GO:0048699 385 0.015
microtubule organizing center organization GO:0031023 1 0.015
regulation of reproductive process GO:2000241 4 0.015
wnt signaling pathway GO:0016055 80 0.015
regulation of dendrite development GO:0050773 3 0.015
regulation of synapse organization GO:0050807 3 0.015
mitochondrion organization GO:0007005 4 0.014
carbohydrate homeostasis GO:0033500 1 0.014
segmentation GO:0035282 97 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
rhythmic process GO:0048511 21 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
eye development GO:0001654 277 0.014
regulation of protein targeting GO:1903533 2 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
regulation of sodium ion transport GO:0002028 2 0.014
positive regulation of cellular process GO:0048522 201 0.014
neuron development GO:0048666 262 0.014
connective tissue development GO:0061448 99 0.014
small molecule metabolic process GO:0044281 77 0.014
Yeast
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
er to golgi vesicle mediated transport GO:0006888 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
Yeast
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
ear development GO:0043583 127 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
negative regulation of protein transport GO:0051224 3 0.013
entrainment of circadian clock GO:0009649 2 0.013
angiogenesis GO:0001525 158 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
actin cytoskeleton organization GO:0030036 63 0.013
blood vessel development GO:0001568 246 0.013
phagocytosis engulfment GO:0006911 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
protein localization to nucleus GO:0034504 3 0.013
heart development GO:0007507 313 0.013
Zebrafish
nuclear envelope organization GO:0006998 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
Yeast
regulation of neural precursor cell proliferation GO:2000177 3 0.013
response to drug GO:0042493 3 0.013
negative regulation of defense response GO:0031348 2 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
positive regulation of signal transduction GO:0009967 56 0.013
entrainment of circadian clock by photoperiod GO:0043153 1 0.013
negative regulation of signal transduction GO:0009968 94 0.013
establishment of localization in cell GO:0051649 77 0.013
cortical actin cytoskeleton organization GO:0030866 1 0.013
regulation of protein polymerization GO:0032271 2 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
carboxylic acid metabolic process GO:0019752 22 0.012
biosynthetic process GO:0009058 294 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
cellular response to starvation GO:0009267 1 0.012
cellular response to external stimulus GO:0071496 2 0.012
response to vitamin GO:0033273 3 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
cellular response to topologically incorrect protein GO:0035967 2 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
cellular response to stress GO:0033554 62 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
cytoskeleton organization GO:0007010 96 0.012
photoperiodism GO:0009648 11 0.012
stem cell division GO:0017145 1 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
single organism membrane fusion GO:0044801 2 0.012
regulation of metal ion transport GO:0010959 4 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
localization of cell GO:0051674 244 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
Yeast
cytokinesis GO:0000910 3 0.012
fatty acid transport GO:0015908 1 0.011
protein modification process GO:0036211 100 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of cell shape GO:0008360 1 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
olfactory bulb development GO:0021772 4 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
convergent extension GO:0060026 118 0.011
cellular component biogenesis GO:0044085 178 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
phosphorylation GO:0016310 69 0.011
negative regulation of cell death GO:0060548 60 0.011
system process GO:0003008 185 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
regulation of lipid transport GO:0032368 4 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
meiotic cell cycle process GO:1903046 3 0.011
leukocyte proliferation GO:0070661 1 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
positive regulation of leukocyte migration GO:0002687 2 0.011
spermatid differentiation GO:0048515 2 0.011
protein acylation GO:0043543 3 0.011
membrane invagination GO:0010324 1 0.011
negative regulation of catabolic process GO:0009895 3 0.011
negative regulation of cell communication GO:0010648 96 0.010
positive regulation of secretion GO:0051047 1 0.010
muscle structure development GO:0061061 196 0.010
spindle assembly GO:0051225 2 0.010
neuroblast differentiation GO:0014016 1 0.010
female meiotic division GO:0007143 2 0.010
cognition GO:0050890 1 0.010
centrosome duplication GO:0051298 1 0.010
response to alkaloid GO:0043279 2 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
macromolecule modification GO:0043412 111 0.010
response to light stimulus GO:0009416 46 0.010
mucopolysaccharide metabolic process GO:1903510 2 0.010
macromolecular complex disassembly GO:0032984 1 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
regulation of glucose import GO:0046324 1 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
response to nutrient GO:0007584 3 0.010
regulation of protein complex assembly GO:0043254 3 0.010

rap2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.011