Danio rerio

48 known processes

smad3a

MAD homolog 3a (Drosophila)

(Aliases: madh3,madh3a,wu:fa99e03,smad3)

smad3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.381
organic substance biosynthetic process GO:1901576 289 0.381
cellular nitrogen compound metabolic process GO:0034641 290 0.312
ameboidal type cell migration GO:0001667 143 0.310
Zebrafish
regulation of apoptotic process GO:0042981 98 0.293
Human
sensory organ development GO:0007423 393 0.293
Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.292
anterior posterior pattern specification GO:0009952 152 0.271
Mouse
regulation of primary metabolic process GO:0080090 311 0.269
cellular macromolecule metabolic process GO:0044260 391 0.262
specification of symmetry GO:0009799 204 0.257
Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.255
tube morphogenesis GO:0035239 349 0.235
Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.223
nucleic acid metabolic process GO:0090304 244 0.213
transcription dna templated GO:0006351 181 0.203
regulation of macromolecule biosynthetic process GO:0010556 225 0.201
larval development GO:0002164 2 0.201
sensory organ morphogenesis GO:0090596 200 0.191
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.189
cell migration GO:0016477 237 0.184
Zebrafish
chordate embryonic development GO:0043009 271 0.183
Mouse
regulation of transcription dna templated GO:0006355 213 0.183
regulation of cellular biosynthetic process GO:0031326 245 0.173
digestive system development GO:0055123 289 0.161
Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.159
heterocycle biosynthetic process GO:0018130 215 0.155
posterior lateral line development GO:0048916 38 0.152
biosynthetic process GO:0009058 294 0.151
embryonic organ morphogenesis GO:0048562 274 0.142
Zebrafish Mouse
multicellular organism growth GO:0035264 4 0.141
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.137
rna biosynthetic process GO:0032774 181 0.133
regulation of cell death GO:0010941 103 0.133
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.131
central nervous system development GO:0007417 387 0.129
heterocycle metabolic process GO:0046483 290 0.129
regulation of stem cell differentiation GO:2000736 4 0.129
Human
aromatic compound biosynthetic process GO:0019438 217 0.126
digestive tract development GO:0048565 265 0.125
Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.124
aging GO:0007568 2 0.123
rna metabolic process GO:0016070 219 0.123
locomotion GO:0040011 313 0.122
Zebrafish
regionalization GO:0003002 274 0.121
Zebrafish Mouse
regulation of cell differentiation GO:0045595 142 0.118
Human Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.116
embryonic organ development GO:0048568 381 0.116
Zebrafish Mouse
response to ketone GO:1901654 1 0.115
cellular biosynthetic process GO:0044249 286 0.114
gastrulation GO:0007369 208 0.112
Zebrafish Mouse
eye development GO:0001654 277 0.108
Mouse
regulation of gene expression GO:0010468 265 0.108
gene expression GO:0010467 252 0.107
stem cell maintenance GO:0019827 4 0.107
brain development GO:0007420 293 0.106
regulation of signal transduction GO:0009966 225 0.106
Human Zebrafish Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.100
Mouse
heart development GO:0007507 313 0.099
Zebrafish Mouse
morphogenesis of an epithelium GO:0002009 333 0.098
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.097
Human Zebrafish Mouse
negative regulation of developmental process GO:0051093 65 0.095
Mouse
protein localization to nucleus GO:0034504 3 0.095
Human
peptidyl serine phosphorylation GO:0018105 1 0.094
organic cyclic compound metabolic process GO:1901360 301 0.094
regulation of rna biosynthetic process GO:2001141 213 0.094
embryonic skeletal system morphogenesis GO:0048704 93 0.093
Mouse
regulation of programmed cell death GO:0043067 101 0.093
Human
system process GO:0003008 185 0.090
regulation of metabolic process GO:0019222 359 0.089
response to hexose GO:0009746 3 0.087
response to glucose GO:0009749 3 0.085
organic cyclic compound biosynthetic process GO:1901362 223 0.084
response to monosaccharide GO:0034284 3 0.084
cell motility GO:0048870 244 0.083
Zebrafish
posterior lateral line system development GO:0048915 46 0.079
gland development GO:0048732 143 0.079
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 2 0.078
cellular carbohydrate metabolic process GO:0044262 4 0.077
phagocytosis GO:0006909 3 0.076
regulation of biological quality GO:0065008 263 0.074
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.073
Mouse
inner ear receptor cell differentiation GO:0060113 29 0.073
regulation of synapse organization GO:0050807 3 0.073
liver development GO:0001889 96 0.072
Mouse
autophagy GO:0006914 4 0.072
skeletal system morphogenesis GO:0048705 102 0.069
Mouse
organelle fusion GO:0048284 3 0.069
signal transduction GO:0007165 455 0.068
Human Zebrafish Mouse
localization of cell GO:0051674 244 0.067
Zebrafish
generation of neurons GO:0048699 385 0.067
positive regulation of cell cycle GO:0045787 3 0.067
Worm
positive regulation of epithelial cell migration GO:0010634 2 0.066
head development GO:0060322 303 0.065
regulation of biosynthetic process GO:0009889 250 0.064
regulation of rna metabolic process GO:0051252 224 0.064
cell death GO:0008219 121 0.064
Human
single organism metabolic process GO:0044710 217 0.064
determination of bilateral symmetry GO:0009855 204 0.063
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.062
regulation of embryonic development GO:0045995 47 0.062
Zebrafish
regulation of signaling GO:0023051 235 0.062
Human Zebrafish Mouse
response to carbohydrate GO:0009743 3 0.062
hepaticobiliary system development GO:0061008 98 0.061
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.061
apoptotic process GO:0006915 116 0.060
Human
neuron differentiation GO:0030182 353 0.059
positive regulation of metabolic process GO:0009893 108 0.059
Human Zebrafish Mouse
embryonic skeletal system development GO:0048706 97 0.058
Mouse
immune system process GO:0002376 241 0.058
Human Zebrafish Mouse
cellular component movement GO:0006928 335 0.058
Zebrafish
endocrine system development GO:0035270 65 0.058
Mouse
connective tissue development GO:0061448 99 0.058
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.057
Human Zebrafish Mouse
muscle structure development GO:0061061 196 0.057
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.057
positive regulation of multicellular organismal process GO:0051240 52 0.055
Human Zebrafish Mouse Worm
cellular ketone metabolic process GO:0042180 11 0.055
wnt signaling pathway GO:0016055 80 0.055
Human
positive regulation of biological process GO:0048518 253 0.055
Human Zebrafish Mouse Worm
regulation of cytokine production GO:0001817 3 0.055
Human
inner ear development GO:0048839 126 0.053
Zebrafish
myeloid cell differentiation GO:0030099 86 0.053
Zebrafish
protein modification process GO:0036211 100 0.053
Human
stem cell differentiation GO:0048863 117 0.052
Human
positive regulation of lipid metabolic process GO:0045834 1 0.052
response to stress GO:0006950 263 0.052
Human Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.052
Human
regulation of carbohydrate metabolic process GO:0006109 4 0.051
glucose homeostasis GO:0042593 1 0.050
cell fate commitment GO:0045165 99 0.050
response to abiotic stimulus GO:0009628 122 0.049
Human
synaptic growth at neuromuscular junction GO:0051124 2 0.048
urogenital system development GO:0001655 97 0.048
Mouse
regulation of multicellular organismal process GO:0051239 277 0.048
Human Zebrafish Mouse Worm
wound healing GO:0042060 90 0.047
Mouse
response to glucocorticoid GO:0051384 1 0.047
muscle tissue development GO:0060537 110 0.046
Mouse
response to external biotic stimulus GO:0043207 97 0.045
Human
negative regulation of gene expression GO:0010629 65 0.045
Human Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.045
Human Zebrafish Mouse
ear development GO:0043583 127 0.044
Zebrafish
carbohydrate biosynthetic process GO:0016051 1 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.043
Human Zebrafish Mouse
carbohydrate metabolic process GO:0005975 12 0.043
immune system development GO:0002520 191 0.042
Zebrafish Mouse
camera type eye development GO:0043010 222 0.042
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.042
Human Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.042
Worm
membrane fusion GO:0061025 2 0.041
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.041
positive regulation of cellular process GO:0048522 201 0.041
Human Zebrafish Mouse Worm
development of primary female sexual characteristics GO:0046545 4 0.041
response to alkaloid GO:0043279 2 0.041
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.040
Human
gtp catabolic process GO:0006184 2 0.040
neuron development GO:0048666 262 0.040
tissue remodeling GO:0048771 4 0.040
synaptic vesicle localization GO:0097479 1 0.040
positive regulation of programmed cell death GO:0043068 29 0.040
Human
nuclear transport GO:0051169 4 0.039
Human
nuclear import GO:0051170 3 0.039
Human
germ line stem cell division GO:0042078 1 0.039
regulation of protein ubiquitination GO:0031396 3 0.039
regulation of cytoplasmic transport GO:1903649 4 0.038
Human
determination of left right symmetry GO:0007368 179 0.038
Zebrafish Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.038
Human Zebrafish Mouse
nucleic acid templated transcription GO:0097659 181 0.038
circulatory system process GO:0003013 87 0.038
muscle cell differentiation GO:0042692 139 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.037
Zebrafish
mechanosensory lateral line system development GO:0048881 49 0.037
protein import into nucleus GO:0006606 3 0.037
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.036
Human Zebrafish Mouse
modulation by virus of host morphology or physiology GO:0019048 1 0.036
Human
cartilage development GO:0051216 96 0.036
Mouse
inner ear receptor cell development GO:0060119 20 0.036
membrane invagination GO:0010324 1 0.036
negative regulation of cellular process GO:0048523 283 0.036
Human Zebrafish Mouse Worm
homeostatic process GO:0042592 142 0.036
response to wounding GO:0009611 116 0.035
Mouse
medulla oblongata development GO:0021550 4 0.035
regulation of protein complex assembly GO:0043254 3 0.035
cell cycle process GO:0022402 53 0.035
Human Worm
tube closure GO:0060606 1 0.035
negative regulation of catabolic process GO:0009895 3 0.035
Human
fin development GO:0033333 77 0.035
maintenance of location GO:0051235 4 0.034
positive regulation of protein complex assembly GO:0031334 2 0.034
stem cell proliferation GO:0072089 4 0.034
negative regulation of cell differentiation GO:0045596 46 0.034
Mouse
cellular component biogenesis GO:0044085 178 0.034
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.034
tissue regeneration GO:0042246 74 0.034
mechanoreceptor differentiation GO:0042490 37 0.033
protein metabolic process GO:0019538 183 0.033
Human
segmentation GO:0035282 97 0.033
Mouse
muscle organ development GO:0007517 101 0.033
Mouse
camera type eye morphogenesis GO:0048593 108 0.033
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
pectoral fin development GO:0033339 50 0.033
ear morphogenesis GO:0042471 64 0.033
Zebrafish
epithelial cell differentiation GO:0030855 116 0.033
Mouse
peptidyl serine modification GO:0018209 2 0.032
cell projection organization GO:0030030 284 0.032
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.032
Human
skeletal muscle organ development GO:0060538 78 0.031
regulation of developmental process GO:0050793 247 0.031
Human Zebrafish Mouse Worm
establishment of synaptic vesicle localization GO:0097480 1 0.031
single fertilization GO:0007338 3 0.031
positive regulation of catabolic process GO:0009896 4 0.031
cellular response to external stimulus GO:0071496 2 0.031
peptidyl threonine phosphorylation GO:0018107 1 0.031
positive regulation of transport GO:0051050 2 0.030
Human
cellular component assembly GO:0022607 170 0.030
Human
eye morphogenesis GO:0048592 144 0.030
regulation of skeletal muscle tissue development GO:0048641 4 0.030
hypothalamus cell differentiation GO:0021979 4 0.030
death GO:0016265 121 0.030
Human
regulation of wound healing GO:0061041 2 0.029
Mouse
mitotic cell cycle GO:0000278 64 0.029
Human Worm
appendage development GO:0048736 80 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
Human
regulation of nervous system development GO:0051960 90 0.029
growth GO:0040007 174 0.029
Human Mouse Worm
synaptic vesicle transport GO:0048489 1 0.029
peptidyl threonine modification GO:0018210 1 0.029
superoxide metabolic process GO:0006801 2 0.029
establishment of protein localization to plasma membrane GO:0090002 1 0.029
positive regulation of cell death GO:0010942 29 0.029
Human
cellular response to lipid GO:0071396 39 0.029
germ line stem cell maintenance GO:0030718 2 0.029
locomotor rhythm GO:0045475 3 0.029
vasculature development GO:0001944 278 0.028
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.028
Mouse
posterior lateral line neuromast primordium migration GO:0048920 12 0.028
cellular response to molecule of bacterial origin GO:0071219 3 0.028
positive regulation of cellular component movement GO:0051272 11 0.028
peripheral nervous system development GO:0007422 55 0.028
macromolecule modification GO:0043412 111 0.028
Human
mesenchyme development GO:0060485 127 0.028
Human Mouse
phagocytosis engulfment GO:0006911 1 0.027
positive regulation of muscle cell differentiation GO:0051149 1 0.027
negative regulation of epithelial cell migration GO:0010633 1 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
Human
nuclear migration GO:0007097 3 0.027
cellular response to biotic stimulus GO:0071216 3 0.027
astrocyte differentiation GO:0048708 1 0.027
stem cell development GO:0048864 82 0.027
Human
neuroblast proliferation GO:0007405 2 0.027
establishment of localization GO:0051234 244 0.027
Human
mitotic cell cycle process GO:1903047 48 0.027
actin polymerization or depolymerization GO:0008154 2 0.027
response to corticosteroid GO:0031960 1 0.026
negative regulation of transcription dna templated GO:0045892 45 0.026
Human Zebrafish Mouse
epithelial tube morphogenesis GO:0060562 148 0.026
Zebrafish Mouse
positive regulation of cell adhesion GO:0045785 1 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
glial cell migration GO:0008347 3 0.026
cell migration involved in gastrulation GO:0042074 79 0.026
Zebrafish
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
Human
cell growth GO:0016049 57 0.025
Human
determination of heart left right asymmetry GO:0061371 117 0.025
Zebrafish Mouse
cell part morphogenesis GO:0032990 246 0.025
energy reserve metabolic process GO:0006112 2 0.025
retina development in camera type eye GO:0060041 146 0.025
renal tubule morphogenesis GO:0061333 1 0.025
hemopoiesis GO:0030097 183 0.025
Zebrafish
oxoacid metabolic process GO:0043436 31 0.025
regulation of synapse assembly GO:0051963 3 0.025
nephron morphogenesis GO:0072028 2 0.025
regulation of myotube differentiation GO:0010830 2 0.025
nephron tubule morphogenesis GO:0072078 1 0.025
positive regulation of biosynthetic process GO:0009891 68 0.025
Human Zebrafish Mouse
single organism nuclear import GO:1902593 3 0.025
Human
multi organism cellular process GO:0044764 2 0.024
Human
mesenchymal cell development GO:0014031 78 0.024
Human
regulation of protein import into nucleus GO:0042306 2 0.024
Human
protein localization to plasma membrane GO:0072659 1 0.024
skeletal system development GO:0001501 181 0.024
Mouse
stem cell division GO:0017145 1 0.024
chemotaxis GO:0006935 104 0.024
regulation of immune system process GO:0002682 34 0.024
Mouse
response to other organism GO:0051707 97 0.024
Human
embryonic viscerocranium morphogenesis GO:0048703 52 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.024
Human
internal protein amino acid acetylation GO:0006475 2 0.024
oligodendrocyte differentiation GO:0048709 23 0.024
otic placode formation GO:0043049 23 0.024
Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.024
response to chemical GO:0042221 320 0.024
Human Mouse
single organism membrane fusion GO:0044801 2 0.024
positive regulation of macromolecule metabolic process GO:0010604 93 0.024
Human Zebrafish Mouse
steroid hormone mediated signaling pathway GO:0043401 9 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.023
fertilization GO:0009566 3 0.023
programmed cell death GO:0012501 119 0.023
Human
phosphate containing compound metabolic process GO:0006796 108 0.023
Human
mesenchymal cell differentiation GO:0048762 87 0.023
Human
positive regulation of cellular catabolic process GO:0031331 3 0.023
negative regulation of multicellular organismal process GO:0051241 69 0.023
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
response to lipid GO:0033993 60 0.023
axon development GO:0061564 166 0.023
positive regulation of rna metabolic process GO:0051254 59 0.023
Human Zebrafish Mouse
positive regulation of cell division GO:0051781 2 0.023
amine metabolic process GO:0009308 2 0.023
gliogenesis GO:0042063 45 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.022
Human Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
Human Zebrafish Mouse
b cell activation GO:0042113 2 0.022
hindbrain development GO:0030902 91 0.022
positive regulation of striated muscle cell differentiation GO:0051155 1 0.022
hard palate development GO:0060022 4 0.022
Zebrafish
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
Human Zebrafish Mouse
regulation of response to stimulus GO:0048583 269 0.022
Human Zebrafish Mouse
ensheathment of neurons GO:0007272 18 0.022
regulation of skeletal muscle fiber development GO:0048742 2 0.022
cellular response to lipopolysaccharide GO:0071222 3 0.022
regulation of cellular component organization GO:0051128 86 0.022
Human
regulation of cell migration GO:0030334 40 0.022
embryonic digestive tract morphogenesis GO:0048557 3 0.022
protein polymerization GO:0051258 4 0.022
regulation of binding GO:0051098 3 0.022
Mouse
regulation of cell activation GO:0050865 1 0.022
positive regulation of immune effector process GO:0002699 3 0.022
ectodermal placode morphogenesis GO:0071697 32 0.022
Zebrafish
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
Human Zebrafish Mouse
regulation of cell shape GO:0008360 1 0.021
positive regulation of nucleic acid templated transcription GO:1903508 57 0.021
Human Zebrafish Mouse
nephron epithelium morphogenesis GO:0072088 1 0.021
regulation of protein transport GO:0051223 3 0.021
Human
regulation of cell development GO:0060284 100 0.021
Human Zebrafish
single organism organelle organization GO:1902589 199 0.021
primitive hemopoiesis GO:0060215 27 0.021
regulation of oocyte development GO:0060281 3 0.021
Zebrafish
regulation of molecular function GO:0065009 70 0.021
Human Mouse
cellular amine metabolic process GO:0044106 2 0.021
adherens junction organization GO:0034332 4 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
neuron projection guidance GO:0097485 86 0.021
reactive oxygen species metabolic process GO:0072593 6 0.021
skin development GO:0043588 54 0.021
regulation of neurogenesis GO:0050767 87 0.021
lateral line system development GO:0048925 76 0.021
forebrain cell migration GO:0021885 1 0.020
heart process GO:0003015 71 0.020
cardiocyte differentiation GO:0035051 44 0.020
sprouting angiogenesis GO:0002040 53 0.020
multi organism process GO:0051704 134 0.020
Human Zebrafish
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.020
gtp metabolic process GO:0046039 4 0.020
axon guidance GO:0007411 86 0.020
hormone secretion GO:0046879 2 0.020
vestibular receptor cell development GO:0060118 3 0.020
transmission of nerve impulse GO:0019226 19 0.020
protein import GO:0017038 3 0.020
Human
regulation of nucleoside metabolic process GO:0009118 2 0.020
regulation of intracellular protein transport GO:0033157 3 0.019
Human
transport GO:0006810 220 0.019
Human
blood circulation GO:0008015 87 0.019
negative regulation of signaling GO:0023057 96 0.019
compound eye development GO:0048749 2 0.019
inner ear morphogenesis GO:0042472 63 0.019
Zebrafish
lipid storage GO:0019915 1 0.018
single organism transport GO:0044765 206 0.018
Human
single organism localization GO:1902578 225 0.018
Human
regulation of protein catabolic process GO:0042176 1 0.018
Human
carbohydrate homeostasis GO:0033500 1 0.018
neutrophil chemotaxis GO:0030593 10 0.018
cellular protein complex assembly GO:0043623 19 0.018
Human
pole plasm assembly GO:0007315 4 0.018
negative regulation of rna biosynthetic process GO:1902679 45 0.018
Human Zebrafish Mouse
negative regulation of apoptotic process GO:0043066 55 0.018
positive regulation of protein polymerization GO:0032273 2 0.018
cell morphogenesis GO:0000902 289 0.018
Human
positive regulation of cytokine production GO:0001819 2 0.018
regulation of cell motility GO:2000145 46 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
Mouse
negative regulation of metabolic process GO:0009892 86 0.018
Human Zebrafish Mouse
regulation of protein metabolic process GO:0051246 56 0.018
Human
small molecule metabolic process GO:0044281 77 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
oxidation reduction process GO:0055114 41 0.018
organelle localization GO:0051640 49 0.018
regulation of neuron migration GO:2001222 2 0.017
regulation of cell projection assembly GO:0060491 4 0.017
spermatid development GO:0007286 2 0.017
positive regulation of histone modification GO:0031058 1 0.017
positive regulation of epithelial cell proliferation GO:0050679 1 0.017
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.017
hormone transport GO:0009914 2 0.017
cellular response to nutrient levels GO:0031669 2 0.017
pronuclear migration GO:0035046 1 0.017
regulation of erythrocyte differentiation GO:0045646 2 0.017
negative regulation of signal transduction GO:0009968 94 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
endodermal cell fate determination GO:0007493 2 0.017
heart contraction GO:0060047 71 0.017
lateral line development GO:0048882 66 0.017
axon extension GO:0048675 45 0.017
ectodermal placode formation GO:0060788 26 0.017
Zebrafish
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
Human Zebrafish Mouse
antimicrobial humoral response GO:0019730 2 0.017
female sex differentiation GO:0046660 4 0.017
positive regulation of cell differentiation GO:0045597 30 0.017
Human Zebrafish Mouse
regulation of jak stat cascade GO:0046425 3 0.017
heart morphogenesis GO:0003007 156 0.017
Zebrafish Mouse
response to uv GO:0009411 3 0.017
positive regulation of locomotion GO:0040017 14 0.016
anterior posterior axis specification GO:0009948 20 0.016
developmental cell growth GO:0048588 52 0.016
mesodermal cell migration GO:0008078 12 0.016
tissue migration GO:0090130 37 0.016
regulation of gtpase activity GO:0043087 2 0.016
microtubule organizing center organization GO:0031023 1 0.016
homeostasis of number of cells GO:0048872 62 0.016
otic vesicle morphogenesis GO:0071600 34 0.016
Zebrafish
regulation of dna replication GO:0006275 3 0.016
erythrocyte homeostasis GO:0034101 55 0.016
response to hydrogen peroxide GO:0042542 3 0.016
modification of morphology or physiology of other organism GO:0035821 4 0.016
Human
pancreas development GO:0031016 84 0.016
organelle organization GO:0006996 227 0.016
cellular response to hypoxia GO:0071456 1 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.016
regulation of chemotaxis GO:0050920 18 0.016
regulation of chondrocyte differentiation GO:0032330 1 0.016
Mouse
response to bacterium GO:0009617 58 0.016
erythrocyte differentiation GO:0030218 54 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.015
myelination GO:0042552 18 0.015
striated muscle cell differentiation GO:0051146 129 0.015
centrosome organization GO:0051297 1 0.015
positive regulation of cell activation GO:0050867 1 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
positive regulation of neuron apoptotic process GO:0043525 1 0.015
kidney development GO:0001822 92 0.015
Mouse
response to organic cyclic compound GO:0014070 51 0.015
regulation of inflammatory response GO:0050727 2 0.015
Mouse
protein acetylation GO:0006473 2 0.015
cell cycle arrest GO:0007050 1 0.015
Human
interspecies interaction between organisms GO:0044419 4 0.015
Human
nuclear export GO:0051168 1 0.015
multi organism reproductive process GO:0044703 36 0.015
Zebrafish
regulation of cellular component movement GO:0051270 55 0.015
peptide transport GO:0015833 1 0.015
peripheral nervous system neuron differentiation GO:0048934 28 0.014
cellular response to radiation GO:0071478 4 0.014
blood vessel development GO:0001568 246 0.014
Zebrafish
mesoderm development GO:0007498 88 0.014
Mouse
bmp signaling pathway GO:0030509 52 0.014
Zebrafish
regulation of heart contraction GO:0008016 32 0.014
cellular response to reactive oxygen species GO:0034614 2 0.014
regulation of autophagy GO:0010506 3 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
Human Zebrafish Mouse
internal peptidyl lysine acetylation GO:0018393 2 0.014
developmental growth GO:0048589 166 0.014
Mouse Worm
single organism carbohydrate metabolic process GO:0044723 12 0.014
sensory system development GO:0048880 76 0.014
regulation of bone remodeling GO:0046850 2 0.014
striated muscle cell development GO:0055002 108 0.014
regulation of protein polymerization GO:0032271 2 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
negative regulation of nucleic acid templated transcription GO:1903507 45 0.014
Human Zebrafish Mouse
embryonic heart tube development GO:0035050 133 0.014
Zebrafish Mouse
modification by symbiont of host morphology or physiology GO:0044003 4 0.014
Human
positive regulation of endothelial cell migration GO:0010595 2 0.014
cranial nerve development GO:0021545 42 0.014
cellular protein metabolic process GO:0044267 129 0.013
Human
defense response GO:0006952 47 0.013
Mouse
establishment of organelle localization GO:0051656 45 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.013
covalent chromatin modification GO:0016569 20 0.013

smad3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.075
musculoskeletal system disease DOID:17 0 0.043
connective tissue disease DOID:65 0 0.043
bone disease DOID:0080001 0 0.030
disease of cellular proliferation DOID:14566 0 0.029
cancer DOID:162 0 0.029
organ system cancer DOID:0050686 0 0.029
nervous system disease DOID:863 0 0.017
cardiomyopathy DOID:0050700 0 0.016
myopathy DOID:423 0 0.016
muscle tissue disease DOID:66 0 0.016
cardiovascular system disease DOID:1287 0 0.016
heart disease DOID:114 0 0.016
muscular disease DOID:0080000 0 0.016
bone development disease DOID:0080006 0 0.016