Danio rerio

39 known processes

sod1

superoxide dismutase 1, soluble

(Aliases: ZSOD,cuzn,Cu/Zn-SOD)

sod1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to superoxide GO:0000303 2 0.726
cellular respiration GO:0045333 3 0.619
Yeast
cellular modified amino acid metabolic process GO:0006575 3 0.590
Mouse
cellular response to superoxide GO:0071451 2 0.537
removal of superoxide radicals GO:0019430 2 0.536
cellular response to oxygen radical GO:0071450 2 0.507
larval development GO:0002164 2 0.482
response to transition metal nanoparticle GO:1990267 28 0.436
aromatic compound biosynthetic process GO:0019438 217 0.421
Yeast
aging GO:0007568 2 0.420
Human Yeast Mouse Fly
hydrogen peroxide metabolic process GO:0042743 2 0.387
Human Mouse
response to stress GO:0006950 263 0.316
regulation of cell communication GO:0010646 232 0.313
Human Mouse
signal transduction GO:0007165 455 0.289
Human Mouse
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.267
Human
response to metal ion GO:0010038 34 0.256
cellular component assembly GO:0022607 170 0.255
cellular macromolecule biosynthetic process GO:0034645 224 0.254
Yeast
neuron differentiation GO:0030182 353 0.250
Mouse
response to external stimulus GO:0009605 264 0.249
positive regulation of biological process GO:0048518 253 0.248
Human Yeast Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.213
Human Yeast
response to copper ion GO:0046688 13 0.204
cellular nitrogen compound metabolic process GO:0034641 290 0.198
Human Yeast Mouse
regulation of rna biosynthetic process GO:2001141 213 0.196
Yeast
superoxide metabolic process GO:0006801 2 0.192
negative regulation of signal transduction GO:0009968 94 0.186
regulation of cellular metabolic process GO:0031323 320 0.186
Human Yeast Mouse Fly
negative regulation of cell communication GO:0010648 96 0.177
response to hydrogen peroxide GO:0042542 3 0.175
Mouse
protein complex biogenesis GO:0070271 30 0.173
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.167
cellular nitrogen compound biosynthetic process GO:0044271 218 0.164
Yeast
regulation of biosynthetic process GO:0009889 250 0.164
Human Yeast
regulation of macromolecule biosynthetic process GO:0010556 225 0.158
Yeast
macromolecular complex subunit organization GO:0043933 74 0.158
regulation of metabolic process GO:0019222 359 0.156
Human Yeast Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.155
Human Yeast Mouse
small molecule catabolic process GO:0044282 3 0.153
macromolecule biosynthetic process GO:0009059 227 0.153
Yeast
reactive nitrogen species metabolic process GO:2001057 0 0.152
response to reactive oxygen species GO:0000302 5 0.151
protein metabolic process GO:0019538 183 0.149
Human Mouse
regulation of reactive oxygen species metabolic process GO:2000377 2 0.148
Human
cellular macromolecule metabolic process GO:0044260 391 0.147
Human Yeast Mouse
heart development GO:0007507 313 0.143
negative regulation of programmed cell death GO:0043069 58 0.141
Mouse
regulation of signal transduction GO:0009966 225 0.139
Human Mouse
regulation of cellular response to oxidative stress GO:1900407 2 0.138
Human
iron ion homeostasis GO:0055072 4 0.136
Mouse
regulation of response to oxidative stress GO:1902882 2 0.135
Human
regulation of macromolecule metabolic process GO:0060255 317 0.134
Human Yeast Mouse
maintenance of location GO:0051235 4 0.131
response to drug GO:0042493 3 0.129
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.128
Human Yeast
cellular amide metabolic process GO:0043603 4 0.127
Mouse
response to inorganic substance GO:0010035 38 0.127
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.126
Human
cellular component biogenesis GO:0044085 178 0.125
locomotory behavior GO:0007626 34 0.124
Mouse
nitrogen compound metabolic process GO:0006807 319 0.122
Human Yeast Mouse
lipid storage GO:0019915 1 0.117
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.117
Yeast
positive regulation of metabolic process GO:0009893 108 0.116
Human Yeast Mouse
gland development GO:0048732 143 0.116
regulation of signaling GO:0023051 235 0.116
Human Mouse
intracellular signal transduction GO:0035556 85 0.113
Human Mouse
regulation of oxidative stress induced cell death GO:1903201 2 0.113
Human
regulation of autophagy GO:0010506 3 0.111
Fly
response to oxidative stress GO:0006979 11 0.111
small molecule metabolic process GO:0044281 77 0.110
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.110
regulation of rna metabolic process GO:0051252 224 0.107
Yeast
regulation of biological quality GO:0065008 263 0.106
muscle cell differentiation GO:0042692 139 0.105
regulation of transcription dna templated GO:0006355 213 0.103
Yeast
nucleobase containing compound biosynthetic process GO:0034654 205 0.103
Yeast
negative regulation of response to stimulus GO:0048585 104 0.103
immune system process GO:0002376 241 0.101
Mouse
liver development GO:0001889 96 0.101
protein homooligomerization GO:0051260 3 0.096
positive regulation of transport GO:0051050 2 0.096
regulation of tube size GO:0035150 2 0.094
Mouse
heart morphogenesis GO:0003007 156 0.092
reactive oxygen species metabolic process GO:0072593 6 0.091
cellular response to reactive oxygen species GO:0034614 2 0.090
regulation of response to stimulus GO:0048583 269 0.086
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.085
Human Yeast
protein complex assembly GO:0006461 30 0.083
single organism metabolic process GO:0044710 217 0.083
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.082
protein complex subunit organization GO:0071822 46 0.082
oxoacid metabolic process GO:0043436 31 0.080
Mouse
nucleic acid templated transcription GO:0097659 181 0.080
Yeast
cellular amino acid metabolic process GO:0006520 7 0.079
Mouse
negative regulation of biological process GO:0048519 304 0.077
Human Yeast Mouse
negative regulation of cellular process GO:0048523 283 0.077
Yeast Mouse
response to chemical GO:0042221 320 0.076
extrinsic apoptotic signaling pathway GO:0097191 3 0.075
regulation of developmental process GO:0050793 247 0.074
Mouse
regulation of blood vessel size GO:0050880 2 0.074
Mouse
respiratory electron transport chain GO:0022904 2 0.072
transmembrane transport GO:0055085 120 0.070
peptide metabolic process GO:0006518 1 0.070
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.069
Human Yeast
macromolecular complex assembly GO:0065003 35 0.068
multicellular organism growth GO:0035264 4 0.067
Mouse
cellular response to molecule of bacterial origin GO:0071219 3 0.067
reactive oxygen species biosynthetic process GO:1903409 1 0.067
Human Mouse
hepaticobiliary system development GO:0061008 98 0.066
negative regulation of signaling GO:0023057 96 0.066
regulation of cellular biosynthetic process GO:0031326 245 0.066
Yeast
regulation of response to stress GO:0080134 36 0.066
Human
rna metabolic process GO:0016070 219 0.066
Yeast
cell migration GO:0016477 237 0.065
organic acid metabolic process GO:0006082 31 0.065
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.064
regulation of multicellular organismal process GO:0051239 277 0.063
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.063
Human Yeast Mouse
heterocycle metabolic process GO:0046483 290 0.062
Human Yeast
transcription dna templated GO:0006351 181 0.062
Yeast
cellular response to lipopolysaccharide GO:0071222 3 0.062
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.062
Human Yeast
regulation of transmembrane transport GO:0034762 18 0.061
alpha amino acid metabolic process GO:1901605 3 0.061
neuron development GO:0048666 262 0.060
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.060
mitochondrion organization GO:0007005 4 0.059
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.058
programmed cell death GO:0012501 119 0.058
Human Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.058
Yeast
regulation of cytokine production GO:0001817 3 0.057
Human
nucleic acid metabolic process GO:0090304 244 0.056
Yeast
atp catabolic process GO:0006200 4 0.055
cellular biosynthetic process GO:0044249 286 0.055
Human Yeast Mouse
regulation of systemic arterial blood pressure GO:0003073 1 0.054
positive regulation of map kinase activity GO:0043406 3 0.053
Mouse
protein oligomerization GO:0051259 7 0.052
positive regulation of cytokine production GO:0001819 2 0.051
Human
sulfur compound metabolic process GO:0006790 13 0.051
Mouse
rna biosynthetic process GO:0032774 181 0.051
Yeast
response to nutrient GO:0007584 3 0.051
metal ion homeostasis GO:0055065 26 0.051
Yeast Mouse
cell morphogenesis GO:0000902 289 0.050
Mouse
locomotion GO:0040011 313 0.048
regulation of protein localization to nucleus GO:1900180 2 0.048
cellular carbohydrate metabolic process GO:0044262 4 0.047
cell death in response to oxidative stress GO:0036473 2 0.047
Human
neurological system process GO:0050877 62 0.046
Mouse
cell cell signaling GO:0007267 52 0.046
hematopoietic or lymphoid organ development GO:0048534 191 0.046
adult behavior GO:0030534 2 0.045
nucleoside monophosphate catabolic process GO:0009125 4 0.044
energy reserve metabolic process GO:0006112 2 0.044
homeostatic process GO:0042592 142 0.044
response to uv GO:0009411 3 0.043
carboxylic acid metabolic process GO:0019752 22 0.043
Mouse
response to temperature stimulus GO:0009266 15 0.043
Mouse
cellular response to stress GO:0033554 62 0.042
apoptotic process GO:0006915 116 0.042
Human Mouse
organonitrogen compound metabolic process GO:1901564 74 0.042
Human Mouse
single organism organelle organization GO:1902589 199 0.042
Mouse
biosynthetic process GO:0009058 294 0.041
Human Yeast Mouse
regulation of cell differentiation GO:0045595 142 0.041
transition metal ion homeostasis GO:0055076 5 0.040
Yeast Mouse
regulation of metal ion transport GO:0010959 4 0.040
macromolecule localization GO:0033036 54 0.040
nucleobase containing compound metabolic process GO:0006139 274 0.040
Human Yeast
cellular component movement GO:0006928 335 0.040
Mouse
response to other organism GO:0051707 97 0.039
cation homeostasis GO:0055080 33 0.038
Yeast Mouse
neurotransmitter transport GO:0006836 2 0.038
circulatory system process GO:0003013 87 0.038
Human Mouse
erk1 and erk2 cascade GO:0070371 4 0.037
response to oxygen radical GO:0000305 2 0.037
cellular response to drug GO:0035690 1 0.037
response to abiotic stimulus GO:0009628 122 0.036
Mouse
regulation of protein transport GO:0051223 3 0.035
electron transport chain GO:0022900 2 0.035
cation transmembrane transport GO:0098655 65 0.035
nitric oxide biosynthetic process GO:0006809 2 0.034
cell death GO:0008219 121 0.034
Human Mouse
organic substance catabolic process GO:1901575 28 0.034
Human
regulation of membrane potential GO:0042391 23 0.034
Human
carboxylic acid catabolic process GO:0046395 3 0.034
cell projection morphogenesis GO:0048858 244 0.034
system process GO:0003008 185 0.033
Human Mouse
regulation of establishment of protein localization GO:0070201 4 0.033
cellular response to chemical stimulus GO:0070887 157 0.032
cellular amino acid biosynthetic process GO:0008652 2 0.032
regulation of erk1 and erk2 cascade GO:0070372 4 0.032
response to external biotic stimulus GO:0043207 97 0.032
negative regulation of developmental process GO:0051093 65 0.032
regulation of cellular ketone metabolic process GO:0010565 7 0.031
muscle cell migration GO:0014812 4 0.031
single organism localization GO:1902578 225 0.030
Mouse
regulation of intracellular signal transduction GO:1902531 57 0.030
Human Mouse
cellular ketone metabolic process GO:0042180 11 0.030
regulation of programmed cell death GO:0043067 101 0.030
Human Mouse
cellular response to biotic stimulus GO:0071216 3 0.030
inorganic cation transmembrane transport GO:0098662 50 0.030
dicarboxylic acid metabolic process GO:0043648 1 0.030
positive regulation of cellular process GO:0048522 201 0.030
Human Yeast Mouse
axon guidance GO:0007411 86 0.029
kidney development GO:0001822 92 0.029
hemopoiesis GO:0030097 183 0.029
protein modification process GO:0036211 100 0.029
Human Mouse
inorganic ion transmembrane transport GO:0098660 57 0.028
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.028
nitric oxide metabolic process GO:0046209 2 0.028
cellular component morphogenesis GO:0032989 336 0.028
Mouse
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
response to glucocorticoid GO:0051384 1 0.027
generation of precursor metabolites and energy GO:0006091 5 0.027
Yeast
carbohydrate biosynthetic process GO:0016051 1 0.027
regulation of cell activation GO:0050865 1 0.027
striated muscle tissue development GO:0014706 110 0.026
negative regulation of oxidative stress induced cell death GO:1903202 2 0.026
muscle structure development GO:0061061 196 0.026
transport GO:0006810 220 0.026
Mouse
nuclear transport GO:0051169 4 0.026
regulation of carbohydrate metabolic process GO:0006109 4 0.025
melanosome transport GO:0032402 19 0.024
protein acetylation GO:0006473 2 0.024
cell aging GO:0007569 2 0.024
Human Yeast
cellular response to oxygen containing compound GO:1901701 20 0.024
establishment of localization GO:0051234 244 0.024
Mouse
regulation of apoptotic process GO:0042981 98 0.024
Human Mouse
response to cold GO:0009409 4 0.024
negative regulation of apoptotic signaling pathway GO:2001234 10 0.024
leukocyte proliferation GO:0070661 1 0.023
pigmentation GO:0043473 85 0.023
peptidyl serine phosphorylation GO:0018105 1 0.023
neuron neuron synaptic transmission GO:0007270 1 0.023
androgen biosynthetic process GO:0006702 1 0.023
response to bacterium GO:0009617 58 0.022
single organism transport GO:0044765 206 0.022
Mouse
negative regulation of cell death GO:0060548 60 0.022
Mouse
neuron projection guidance GO:0097485 86 0.022
negative regulation of intracellular signal transduction GO:1902532 22 0.022
vascular process in circulatory system GO:0003018 6 0.022
Mouse
head development GO:0060322 303 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
Human
regulation of protein catabolic process GO:0042176 1 0.021
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.021
oxidation reduction process GO:0055114 41 0.021
gene expression GO:0010467 252 0.020
Yeast
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
blood circulation GO:0008015 87 0.020
Human Mouse
cell proliferation GO:0008283 80 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
Yeast Mouse
striated muscle cell differentiation GO:0051146 129 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
protein acylation GO:0043543 3 0.019
synaptic vesicle localization GO:0097479 1 0.019
brain development GO:0007420 293 0.019
positive regulation of immune effector process GO:0002699 3 0.019
positive regulation of cell communication GO:0010647 56 0.019
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.019
Yeast
regulation of protein metabolic process GO:0051246 56 0.019
Human Mouse
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
negative regulation of cell differentiation GO:0045596 46 0.019
chemotaxis GO:0006935 104 0.019
regulation of carbohydrate biosynthetic process GO:0043255 1 0.018
immune system development GO:0002520 191 0.018
cellular protein metabolic process GO:0044267 129 0.018
Human Mouse
response to axon injury GO:0048678 14 0.018
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.018
response to biotic stimulus GO:0009607 97 0.018
behavior GO:0007610 74 0.018
Mouse
cell part morphogenesis GO:0032990 246 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
Mouse
striated muscle cell development GO:0055002 108 0.018
positive regulation of secretion GO:0051047 1 0.018
response to activity GO:0014823 14 0.018
muscle cell development GO:0055001 115 0.018
regulation of cysteine type endopeptidase activity GO:2000116 21 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
negative regulation of intracellular transport GO:0032387 3 0.017
organelle fusion GO:0048284 3 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
response to cadmium ion GO:0046686 14 0.017
dopamine biosynthetic process GO:0042416 2 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
detection of chemical stimulus GO:0009593 4 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
sensory organ development GO:0007423 393 0.017
Mouse
negative regulation of protein processing GO:0010955 10 0.017
regulation of transporter activity GO:0032409 2 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.017
macromolecule modification GO:0043412 111 0.017
Human Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
regulation of cellular response to stress GO:0080135 20 0.017
Human
activation of mapk activity GO:0000187 3 0.017
Mouse
positive regulation of cell substrate adhesion GO:0010811 1 0.017
protein stabilization GO:0050821 2 0.016
Yeast
production of molecular mediator of immune response GO:0002440 2 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
Human Mouse
negative regulation of protein transport GO:0051224 3 0.016
organelle organization GO:0006996 227 0.016
Mouse
cation transport GO:0006812 81 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
Yeast
muscle tissue development GO:0060537 110 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
intrinsic apoptotic signaling pathway GO:0097193 20 0.016
Human
specification of symmetry GO:0009799 204 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
ion transport GO:0006811 114 0.016
regulation of hydrolase activity GO:0051336 28 0.016
Human
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
regulation of apoptotic signaling pathway GO:2001233 12 0.016
Human
very long chain fatty acid biosynthetic process GO:0042761 4 0.016
axonogenesis GO:0007409 152 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
negative regulation of kinase activity GO:0033673 4 0.016
synaptic vesicle transport GO:0048489 1 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
Mouse
cellular response to nutrient levels GO:0031669 2 0.015
regulation of localization GO:0032879 104 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
regulation of endopeptidase activity GO:0052548 23 0.015
cytoskeleton organization GO:0007010 96 0.015
Mouse
nuclear export GO:0051168 1 0.015
death GO:0016265 121 0.015
Human Mouse
response to organic substance GO:0010033 153 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
endosomal transport GO:0016197 2 0.015
negative regulation of protein maturation GO:1903318 10 0.015
regulation of response to biotic stimulus GO:0002831 2 0.014
regulation of cell proliferation GO:0042127 37 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
fatty acid beta oxidation GO:0006635 1 0.014
myotube differentiation GO:0014902 45 0.014
urogenital system development GO:0001655 97 0.014
regulation of anatomical structure size GO:0090066 33 0.014
Mouse
protein modification by small protein removal GO:0070646 1 0.014
stem cell maintenance GO:0019827 4 0.014
regulation of sequestering of calcium ion GO:0051282 4 0.014
pigment granule localization GO:0051875 25 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
Yeast
regulation of dendrite development GO:0050773 3 0.014
lipid oxidation GO:0034440 1 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
regulation of molecular function GO:0065009 70 0.014
Human Yeast Mouse
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
cellular catabolic process GO:0044248 27 0.014
Human Fly
inner ear development GO:0048839 126 0.013
Mouse
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
regulation of muscle contraction GO:0006937 3 0.013
Mouse
protein import into nucleus GO:0006606 3 0.013
catabolic process GO:0009056 32 0.013
Human Fly
response to corticosteroid GO:0031960 1 0.013
regulation of reproductive process GO:2000241 4 0.013
signal transduction by phosphorylation GO:0023014 18 0.013
Mouse
metal ion transport GO:0030001 58 0.013
regulation of cell death GO:0010941 103 0.013
Human Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.013
Human
sensory perception of chemical stimulus GO:0007606 3 0.013
cellular response to oxidative stress GO:0034599 5 0.013
androgen metabolic process GO:0008209 2 0.013
nuclear import GO:0051170 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
regulation of peptidase activity GO:0052547 23 0.012
regulation of gene expression GO:0010468 265 0.012
Yeast
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
neuron death GO:0070997 21 0.012
Mouse
negative regulation of response to dna damage stimulus GO:2001021 3 0.012
single organism reproductive process GO:0044702 40 0.012
Mouse
cell type specific apoptotic process GO:0097285 22 0.012
Mouse
signal transduction in absence of ligand GO:0038034 1 0.012
organic acid catabolic process GO:0016054 3 0.012
cellular protein modification process GO:0006464 100 0.012
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.012
Human Yeast
fatty acid oxidation GO:0019395 1 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
cellular response to external stimulus GO:0071496 2 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
phosphorus metabolic process GO:0006793 109 0.012
Human Mouse
protein localization GO:0008104 40 0.012
protein import GO:0017038 3 0.012
growth GO:0040007 174 0.012
Mouse
sequestering of metal ion GO:0051238 3 0.012
muscle fiber development GO:0048747 52 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of system process GO:0044057 40 0.011
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
Yeast
ion homeostasis GO:0050801 41 0.011
Yeast Mouse
regulation of neuron apoptotic process GO:0043523 17 0.011
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.011
Yeast
cell fate commitment GO:0045165 99 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
regulation of binding GO:0051098 3 0.011
carboxylic acid biosynthetic process GO:0046394 12 0.011
neuron apoptotic process GO:0051402 20 0.011
Mouse
protein dephosphorylation GO:0006470 3 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
negative regulation of proteolysis GO:0045861 10 0.011
regulation of response to external stimulus GO:0032101 31 0.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.011
peptidyl serine modification GO:0018209 2 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
positive regulation of cell activation GO:0050867 1 0.011
tight junction assembly GO:0070830 1 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
gtp metabolic process GO:0046039 4 0.011
Human
female sex differentiation GO:0046660 4 0.010
Mouse
generation of neurons GO:0048699 385 0.010
Mouse
protein localization to nucleus GO:0034504 3 0.010
immune response GO:0006955 28 0.010
single organism nuclear import GO:1902593 3 0.010
cell projection organization GO:0030030 284 0.010
Mouse
epithelial tube morphogenesis GO:0060562 148 0.010
cardiac muscle tissue development GO:0048738 48 0.010
neuron projection morphogenesis GO:0048812 161 0.010
pigment granule transport GO:0051904 19 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
Yeast

sod1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.030
mitochondrial metabolism disease DOID:700 0 0.020
leigh disease DOID:3652 0 0.020
synucleinopathy DOID:0050890 0 0.018
central nervous system disease DOID:331 0 0.018
Human
nervous system disease DOID:863 0 0.018
Human
disease of anatomical entity DOID:7 0 0.018
Human
neurodegenerative disease DOID:1289 0 0.018
Human
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011