IMP

Process View

Drosophila melanogaster

13 genes annotated in fly

skeletal muscle tissue development

The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "skeletal muscle tissue development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "skeletal muscle tissue development" (in gray)

Name	Description	Probability	Func Analog Organism
ci	cubitus interruptus	0.857	Fly
sns	sticks and stones	0.565	Zebrafish Mouse
pan	pangolin	0.464	Mouse
EcR	Ecdysone receptor	0.421
hth	homothorax	0.319
Egfr	Epidermal growth factor receptor	0.269	Rat
stumps	CG31317 gene product from transcript CG31317-RC	0.234
CadN	Cadherin-N	0.227
BicD	Bicaudal D	0.226
Akt1	CG4006 gene product from transcript CG4006-RA	0.220
Rya-r44F	Ryanodine receptor 44F	0.215	Mouse
InR	Insulin-like receptor	0.193
Antp	Antennapedia	0.187
mys	myospheroid	0.182
wg	wingless	0.182
S6k	RPS6-p70-protein kinase	0.177	Rat
Gug	Grunge	0.163
nab	CG33545 gene product from transcript CG33545-RC	0.160
slou	slouch	0.149
shn	schnurri	0.145	Mouse
Moe	Moesin	0.137
htl	heartless	0.122
Mad	Mothers against dpp	0.118
lbe	ladybird early	0.109
rols	rolling pebbles	0.108
up	upheld	0.105
stck	steamer duck	0.103
hbs	hibris	0.103	Zebrafish Mouse
gsb	gooseberry	0.099	Mouse
en	engrailed	0.098
Eip75B	Ecdysone-induced protein 75B	0.096	Mouse
eve	even skipped	0.094
vg	vestigial	0.091
HGTX	CG13475 gene product from transcript CG13475-RB	0.091
Imp	IGF-II mRNA-binding protein	0.088
ex	expanded	0.084
LanB1	CG7123 gene product from transcript CG7123-RA	0.081
Mlc2	Myosin light chain 2	0.079
Ric	Ras which interacts with Calmodulin	0.079
trx	trithorax	0.076
smo	smoothened	0.076	Zebrafish Mouse
kis	kismet	0.072
nau	nautilus	0.069	Zebrafish Mouse
Dlic	Dynein light intermediate chain	0.068
prd	paired	0.067	Mouse
egh	egghead	0.066
G-oalpha47A	G protein oalpha 47A	0.063
phyl	phyllopod	0.062
Ppn	Papilin	0.062
Pp2B-14D	Protein phosphatase 2B at 14D	0.061	Mouse
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.059
norpA	no receptor potential A	0.056
H	Hairless	0.056
wb	wing blister	0.055
Fas2	Fasciclin 2	0.050
mael	maelstrom	0.050
Vrp1	Verprolin 1	0.050
pdm2	POU domain protein 2	0.049
LanB2	Laminin B2	0.047	Zebrafish
dnc	dunce	0.045
if	inflated	0.045
Mhc	Myosin heavy chain	0.044	Zebrafish Mouse
Ubx	Ultrabithorax	0.043
pnt	pointed	0.041
ash2	absent, small, or homeotic discs 2	0.041
slo	slowpoke	0.039
Tm2	Tropomyosin 2	0.039
dome	domeless	0.038
Cg25C	Collagen type IV	0.037	Fly
Grip	Glutamate receptor binding protein	0.036
Pkc98E	Protein C kinase 98E	0.036
Act87E	Actin 87E	0.036
slmb	supernumerary limbs	0.036
rasp	CG11495 gene product from transcript CG11495-RA	0.035
Cul-3	Cullin-3	0.035
CG7145	CG7145 gene product from transcript CG7145-RD	0.033
Ser	Serrate	0.033
sd	scalloped	0.032
gro	groucho	0.032
Arp66B	Actin-related protein 66B	0.031
Rheb	CG1081 gene product from transcript CG1081-RA	0.031
jeb	jelly belly	0.030
tsh	teashirt	0.030
kn	knot	0.030
CG9007	CG9007 gene product from transcript CG9007-RA	0.030
Nrg	Neuroglian	0.030
Mef2	Myocyte enhancer factor 2	0.029
foxo	forkhead box, sub-group O	0.029
tomosyn	CG17762 gene product from transcript CG17762-RB	0.029
sr	stripe	0.028	Mouse
sty	sprouty	0.028	Zebrafish
Atx2	Ataxin-2	0.028
simj	simjang	0.027
ap	apterous	0.027
mirr	mirror	0.027
Actn	alpha actinin	0.027	Zebrafish
pigs	pickled eggs	0.027
dco	discs overgrown	0.026
inv	invected	0.026
lbl	ladybird late	0.026
Prm	Paramyosin	0.026
run	runt	0.025
wit	wishful thinking	0.025
Nmdar1	NMDA receptor 1	0.025
disco	disconnected	0.025
slp1	sloppy paired 1	0.025
kon	kon-tiki	0.025
Pka-R1	cAMP-dependent protein kinase R1	0.024
G-salpha60A	G protein salpha 60A	0.024
CG1347	CG1347 gene product from transcript CG1347-RB	0.024
org-1	optomotor-blind-related-gene-1	0.024	Mouse
Thor	CG8846 gene product from transcript CG8846-RA	0.023
Max	CG9648 gene product from transcript CG9648-RA	0.023
CG32810	CG32810 gene product from transcript CG32810-RB	0.023
CRMP	Collapsin Response Mediator Protein	0.023
tna	tonalli	0.022
VAChT	CG32848 gene product from transcript CG32848-RA	0.022
tim	timeless	0.021
Pvr	PDGF- and VEGF-receptor related	0.021	Rat
Ace	Acetylcholine esterase	0.021
vkg	viking	0.021
dpp	decapentaplegic	0.021	Human Mouse
srpk79D	serine-arginine protein kinase at 79D	0.020	Mouse
fng	fringe	0.020
rst	roughest	0.020
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.020
ds	dachsous	0.019
zip	zipper	0.019	Human
p38b	CG7393 gene product from transcript CG7393-RA	0.019	Mouse
dsh	dishevelled	0.019
CG4857	CG4857 gene product from transcript CG4857-RD	0.019
HLH54F	CG5005 gene product from transcript CG5005-RA	0.019
zfh1	Zn finger homeodomain 1	0.019
Mlp84B	Muscle LIM protein at 84B	0.019
cher	cheerio	0.019	Mouse
skpA	CG16983 gene product from transcript CG16983-RD	0.019
Mekk1	CG7717 gene product from transcript CG7717-RB	0.018
bin	biniou	0.018
mbc	myoblast city	0.018
gbb	glass bottom boat	0.018
pb	proboscipedia	0.018
kirre	kin of irre	0.018
Pde8	Phosphodiesterase 8	0.017
dally	division abnormally delayed	0.017
Poxn	Pox neuro	0.017
Pp1alpha-96A	Protein phosphatase 1alpha at 96A	0.017
fas	faint sausage	0.017
enc	encore	0.016
Abd-B	Abdominal B	0.016
Clk	Clock	0.016
bnl	branchless	0.016
dos	daughter of sevenless	0.016
sens	senseless	0.016
wupA	wings up A	0.015
spdo	sanpodo	0.015
chb	chromosome bows	0.015
arm	armadillo	0.015
twi	twist	0.015	Mouse
blow	blown fuse	0.015
ham	hamlet	0.014
Syx1A	Syntaxin 1A	0.014
Eip74EF	Ecdysone-induced protein 74EF	0.014
usp	ultraspiracle	0.014
betaTub60D	beta-Tubulin at 60D	0.014
shot	short stop	0.014
rho	rhomboid	0.014
nej	nejire	0.014
CG42574	CG42574 gene product from transcript CG42574-RE	0.014
Rho1	CG8416 gene product from transcript CG8416-RB	0.014	Mouse
emc	extra macrochaetae	0.014	Mouse
LanA	Laminin A	0.014
grn	grain	0.014
Mpk2	CG5475 gene product from transcript CG5475-RB	0.013	Mouse
bab2	CG9102 gene product from transcript CG9102-RA	0.013
Zasp52	Z band alternatively spliced PDZ-motif protein 52	0.013
bi	bifid	0.013	Human
kay	kayak	0.013	Mouse
ptc	patched	0.013
Vhl	von Hippel-Lindau	0.013
CG11286	CG11286 gene product from transcript CG11286-RA	0.013
per	period	0.012
loco	locomotion defects	0.012
put	punt	0.012
tweek	CG42555 gene product from transcript CG42555-RD	0.012
byn	brachyenteron	0.012
Catsup	Catecholamines up	0.012
Lrt	Leucine-rich tendon-specific protein	0.012
Act57B	Actin 57B	0.012
Cp190	Centrosomal protein 190kD	0.012
sing	singles bar	0.012
inaE	inactivation no afterpotential E	0.011
stan	starry night	0.011
sqd	squid	0.011
htt	huntingtin	0.011
ss	spineless	0.011
cer	crammer	0.011
Stat92E	Signal-transducer and activator of transcription protein at 92E	0.011
Psn	Presenilin	0.011
dac	dachshund	0.011
Cat	Catalase	0.011
Msp-300	Muscle-specific protein 300	0.011
ush	u-shaped	0.011
Snoo	Sno oncogene	0.011
Ddc	Dopa decarboxylase	0.011
scny	scrawny	0.011
Mnt	CG13316 gene product from transcript CG13316-RD	0.010
Mmp1	Matrix metalloproteinase 1	0.010
Pka-C1	cAMP-dependent protein kinase 1	0.010
in	inturned	0.010
Prat2	Phosphoribosylamidotransferase 2	0.010
hkb	huckebein	0.010