IMP

Process View

Drosophila melanogaster

22 genes annotated in fly

oocyte microtubule cytoskeleton polarization

Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "oocyte microtubule cytoskeleton polarization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "oocyte microtubule cytoskeleton polarization" (in gray)

Name	Description	Probability	Func Analog Organism
Cdc42	CG12530 gene product from transcript CG12530-RA	0.978	Fly
slmb	supernumerary limbs	0.966
sqd	squid	0.960
BicD	Bicaudal D	0.896
par-1	CG8201 gene product from transcript CG8201-RA	0.885
Dhc64C	Dynein heavy chain 64C	0.851
baz	bazooka	0.830
aPKC	atypical protein kinase C	0.820
Src64B	Src oncogene at 64B	0.804
TER94	CG2331 gene product from transcript CG2331-RA	0.788
ovo	CG6824 gene product from transcript CG6824-RE	0.768
stai	stathmin	0.727
pum	pumilio	0.718
chic	chickadee	0.717
Atx2	Ataxin-2	0.644
Lam	Lamin	0.585
sqh	spaghetti squash	0.583
cact	cactus	0.580
gish	gilgamesh	0.580
rok	Rho-kinase	0.550
Rab5	Rab-protein 5	0.495
Lis-1	Lissencephaly-1	0.478
Dlic	Dynein light intermediate chain	0.456
nos	nanos	0.448
Sop2	Suppressor of profilin 2	0.411
egh	egghead	0.408
wdb	widerborst	0.405
sn	singed	0.404
Rbsn-5	Rabenosyn-5	0.402
eff	effete	0.378
aret	arrest	0.352
arm	armadillo	0.325
cpa	capping protein alpha	0.295
tsr	twinstar	0.263
sec5	CG8843 gene product from transcript CG8843-RA	0.258
puc	puckered	0.256
Rac1	CG2248 gene product from transcript CG2248-RA	0.252	Fly
Khc	Kinesin heavy chain	0.238
da	daughterless	0.234
Chc	Clathrin heavy chain	0.232
Hrb27C	Heterogeneous nuclear ribonucleoprotein at 27C	0.230
mael	maelstrom	0.227
trc	tricornered	0.216
sec6	CG5341 gene product from transcript CG5341-RA	0.215
hpo	hippo	0.206
sgl	sugarless	0.196
osk	oskar	0.189
Gprk2	G protein-coupled receptor kinase 2	0.188
shg	shotgun	0.186
vas	vasa	0.174
Dcr-1	Dicer-1	0.172
Akt1	CG4006 gene product from transcript CG4006-RA	0.169
Fmr1	CG6203 gene product from transcript CG6203-RC	0.162
sds22	CG5851 gene product from transcript CG5851-RA	0.146
Tm1	Tropomyosin 1	0.136
par-6	CG5884 gene product from transcript CG5884-RA	0.130
orb	oo18 RNA-binding protein	0.128
rin	rasputin	0.120
bel	belle	0.120
ena	enabled	0.117
Rho1	CG8416 gene product from transcript CG8416-RB	0.109
Pten	CG5671 gene product from transcript CG5671-RB	0.106
brat	brain tumor	0.101
Arp66B	Actin-related protein 66B	0.099
14-3-3epsilon	CG31196 gene product from transcript CG31196-RA	0.097
dsh	dishevelled	0.091
Pak3	CG14895 gene product from transcript CG14895-RA	0.090
car	carnation	0.088
mats	mob as tumor suppressor	0.083
spin	spinster	0.080
Hsp83	Heat shock protein 83	0.080
jar	jaguar	0.078
Shc	SHC-adaptor protein	0.078
Nup154	Nucleoporin 154	0.077
Mi-2	CG8103 gene product from transcript CG8103-RA	0.076
Mrtf	Myocardin-related transcription factor	0.075
tsu	tsunagi	0.073
glo	glorund	0.071
lic	licorne	0.070
Rbf	Retinoblastoma-family protein	0.066
RpII215	RNA polymerase II 215kD subunit	0.065
Ube3a	Ubiquitin protein ligase E3A	0.064
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.064
Pabp2	CG2163 gene product from transcript CG2163-RA	0.063
CSN5	COP9 complex homolog subunit 5	0.062
Ets97D	Ets at 97D	0.061
Psa	Puromycin sensitive aminopeptidase	0.060
ecd	ecdysoneless	0.060
cup	CG11181 gene product from transcript CG11181-RB	0.060
grk	gurken	0.059
zip	zipper	0.058
Syx1A	Syntaxin 1A	0.058
smt3	CG4494 gene product from transcript CG4494-RA	0.057
4EHP	CG33100 gene product from transcript CG33100-RA	0.054
me31B	maternal expression at 31B	0.053
Jra	Jun-related antigen	0.053
scb	scab	0.052
mts	microtubule star	0.052
fwd	four wheel drive	0.051
hb	hunchback	0.049
bcd	bicoid	0.049
CG11242	CG11242 gene product from transcript CG11242-RA	0.048
ctp	cut up	0.048
spn-F	CG12114 gene product from transcript CG12114-RA	0.048
Rac2	CG8556 gene product from transcript CG8556-RA	0.048
egg	eggless	0.047
CG17838	CG17838 gene product from transcript CG17838-RA	0.047
Sxl	Sex lethal	0.045
ssh	slingshot	0.045
armi	armitage	0.044
pasha	partner of drosha	0.043
capt	capulet	0.043
bun	bunched	0.043
qm	quemao	0.043
spen	split ends	0.042
Top1	Topoisomerase 1	0.040
kuz	kuzbanian	0.040
cpb	capping protein beta	0.039
AGO1	Argonaute-1	0.039
Rab7	Rab-protein 7	0.039
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.037
Gef26	CG9491 gene product from transcript CG9491-RB	0.037
CG11347	CG11347 gene product from transcript CG11347-RE	0.036
nudE	CG8104 gene product from transcript CG8104-RB	0.036
Rop	Ras opposite	0.035
psidin	phagocyte signaling impaired	0.035
loco	locomotion defects	0.034
flr	flare	0.034
krz	kurtz	0.033
crb	crumbs	0.033
TSG101	tumor suppressor protein 101	0.032
Ggamma1	G protein gamma 1	0.032
neb	nebbish	0.032
twin	CG31137 gene product from transcript CG31137-RB	0.031
BicC	Bicaudal C	0.031
Abl	Abl tyrosine kinase	0.030
spir	spire	0.030
Catsup	Catecholamines up	0.030
MED6	Mediator complex subunit 6	0.029
mr	morula	0.029
mop	myopic	0.028
pelo	pelota	0.028
Vps45	Vacuolar protein sorting 45	0.028
l(2)35Bg	lethal (2) 35Bg	0.027
Dcp1	Decapping protein 1	0.027
jagn	jagunal	0.027
Ctr1A	Copper transporter 1A	0.027
tral	trailer hitch	0.026
psq	pipsqueak	0.026
pic	piccolo	0.026
Act5C	Actin 5C	0.026
sbr	small bristles	0.026
ird1	immune response deficient 1	0.025
S6kII	RPS6-protein kinase-II	0.025
ric8a	CG15797 gene product from transcript CG15797-RA	0.025
Eps-15	Epidermal growth factor receptor pathway substrate clone 15	0.025
retn	retained	0.024
dp	dumpy	0.024
l(2)gl	lethal (2) giant larvae	0.024
Pi3K21B	CG2699 gene product from transcript CG2699-RA	0.024
por	porcupine	0.024
exu	exuperantia	0.024
ras	raspberry	0.024
dally	division abnormally delayed	0.024
Dhod	Dihydroorotate dehydrogenase	0.023
Eip75B	Ecdysone-induced protein 75B	0.023
CrebB-17A	Cyclic-AMP response element binding protein B at 17A	0.023
sktl	skittles	0.023
rno	rhinoceros	0.023
Vrp1	Verprolin 1	0.022
sm	smooth	0.022
lsn	larsen	0.022
rtet	tetracycline resistance	0.022
S6k	RPS6-p70-protein kinase	0.022
CG4699	CG4699 gene product from transcript CG4699-RJ	0.021
dome	domeless	0.021
gatA	glutamyl-tRNA amidotransferase subunit A	0.021
CkIalpha	Casein kinase Ialpha	0.021
Tl	Toll	0.021
Rpn6	Proteasome p44.5 subunit	0.021
ran	CG1404 gene product from transcript CG1404-RB	0.020
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.020
capu	cappuccino	0.020
CG4030	CG4030 gene product from transcript CG4030-RA	0.020
lqf	liquid facets	0.020
cno	canoe	0.019
mei-P26	CG12218 gene product from transcript CG12218-RA	0.019
Rala	Ras-related protein	0.019
WASp	CG1520 gene product from transcript CG1520-RA	0.019
pnt	pointed	0.019
Sgt1	CG9617 gene product from transcript CG9617-RA	0.019
Cul-5	Cullin-5	0.019
Vps25	Vacuolar protein sorting 25	0.019
vib	vibrator	0.019
out	outsiders	0.018
simj	simjang	0.018
Cul-3	Cullin-3	0.018
bin3	bicoid-interacting protein 3	0.018
l(1)G0232	lethal (1) G0232	0.018
Arf79F	ADP ribosylation factor 79F	0.018
Dmn	Dynamitin	0.018
squ	squash	0.017
Ephrin	CG1862 gene product from transcript CG1862-RA	0.017
otu	ovarian tumor	0.017
Smr	Smrter	0.017
nmo	nemo	0.017
HSPC300	CG30173 gene product from transcript CG30173-RA	0.017
sqz	squeeze	0.017
Med	Medea	0.016
pie	pineapple eye	0.016
abs	abstrakt	0.016
mirr	mirror	0.016
G-oalpha47A	G protein oalpha 47A	0.016
Src42A	Src oncogene at 42A	0.016
Atg1	Autophagy-specific gene 1	0.016
ea	easter	0.016
Tom34	Translocase of outer membrane 34	0.016
pAbp	polyA-binding protein	0.016
Fs(2)Ket	Female sterile (2) Ketel	0.016
dia	diaphanous	0.016
Caki	Calcium/calmodulin-dependent protein kinase	0.015
Tis11	Tis11 homolog	0.015
Fpps	Farnesyl pyrophosphate synthase	0.015
spas	spastin	0.015
fry	furry	0.015
gig	gigas	0.015
r2d2	CG7138 gene product from transcript CG7138-RB	0.015
lwr	lesswright	0.015
Adgf-A	Adenosine deaminase-related growth factor A	0.015
cni	cornichon	0.015
Vang	Van Gogh	0.014
ik2	IkappaB kinase-like 2	0.014
spn-D	spindle D	0.014
Past1	Putative Achaete Scute Target 1	0.014
CG10092	CG10092 gene product from transcript CG10092-RA	0.014
adp	adipose	0.014
Patj	CG12021 gene product from transcript CG12021-RC	0.014
frc	fringe connection	0.014
elav	embryonic lethal abnormal vision	0.014
R	Roughened	0.014
Ddc	Dopa decarboxylase	0.014
hts	hu li tai shao	0.014
skd	skuld	0.014
dhd	deadhead	0.014
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.014
Lasp	CG3849 gene product from transcript CG3849-RB	0.013
Pcaf	CG4107 gene product from transcript CG4107-RA	0.013
tud	tudor	0.013
shark	Src homology 2, ankyrin repeat, tyrosine kinase	0.013
eIF-4a	Eukaryotic initiation factor 4a	0.013
enc	encore	0.013
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.013
alphaTub67C	alpha-Tubulin at 67C	0.013
Hop	Hsp70/Hsp90 organizing protein homolog	0.013
Cam	Calmodulin	0.013
Nrg	Neuroglian	0.013
Syx13	Syntaxin 13	0.013
Cip4	CG15015 gene product from transcript CG15015-RA	0.013
Su(Tpl)	CG32217 gene product from transcript CG32217-RB	0.013
CG6854	CG6854 gene product from transcript CG6854-RC	0.012
RpL15	Ribosomal protein L15	0.012
flw	flapwing	0.012
tko	technical knockout	0.012
CrebA	Cyclic-AMP response element binding protein A	0.012
Vps36	Vacuolar protein sorting 36	0.012
Nmdar1	NMDA receptor 1	0.012
piwi	CG6122 gene product from transcript CG6122-RA	0.012
Paip2	polyA-binding protein interacting protein 2	0.012
pcs	parcas	0.012
grh	grainy head	0.012
Pka-C1	cAMP-dependent protein kinase 1	0.012
Btk29A	Btk family kinase at 29A	0.012
mfrn	mitoferrin	0.012
twf	twinfilin	0.012
Atg7	Autophagy-specific gene 7	0.012
be	ben	0.012
homer	CG11324 gene product from transcript CG11324-RC	0.011
l(3)01239	lethal (3) 01239	0.011
EloA	Elongin A	0.011
dos	daughter of sevenless	0.011
wun2	wunen-2	0.011
ple	pale	0.011
phol	pleiohomeotic like	0.011
spn-A	spindle A	0.011
scny	scrawny	0.011
ZnT35C	CG3994 gene product from transcript CG3994-RA	0.011
sano	serrano	0.011
Pka-R2	cAMP-dependent protein kinase R2	0.011
Rsf1	Repressor splicing factor 1	0.011
wkd	whacked	0.011
sw	short wing	0.011
AdoR	Adenosine receptor	0.011
PGRP-LE	Peptidoglycan recognition protein LE	0.011
CG10260	CG10260 gene product from transcript CG10260-RB	0.011
Rab14	Rab-protein 14	0.010
lqfR	liquid facets-Related	0.010
lilli	lilliputian	0.010
blow	blown fuse	0.010
CG11188	CG11188 gene product from transcript CG11188-RA	0.010
fs(1)M3	female sterile (1) M3	0.010
GluRIIE	Glutamate receptor IIE	0.010
spn-E	spindle E	0.010
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.010
SRPK	CG8174 gene product from transcript CG8174-RA	0.010
Cyp18a1	Cytochrome P450-18a1	0.010