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Drosophila melanogaster

22 genes annotated in fly

gene silencing by mirna

Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gene silencing by mirna"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "gene silencing by mirna" (in gray)

Name	Description	Probability	Func Analog Organism
pasha	partner of drosha	0.621
lid	little imaginal discs	0.575
Vps16A	Vacuolar protein sorting 16A	0.492
Ge-1	CG6181 gene product from transcript CG6181-RA	0.457
AGO1	Argonaute-1	0.440
sxc	super sex combs	0.399
drosha	CG8730 gene product from transcript CG8730-RA	0.368
Nipped-A	CG33554 gene product from transcript CG33554-RE	0.311
CG9772	CG9772 gene product from transcript CG9772-RB	0.269
tho2	CG31671 gene product from transcript CG31671-RA	0.250
sw	short wing	0.226
Rm62	CG10279 gene product from transcript CG10279-RD	0.202
lig	lingerer	0.176
Dlic	Dynein light intermediate chain	0.156
Tao-1	CG14217 gene product from transcript CG14217-RF	0.149
loqs	loquacious	0.147
Aos1	CG12276 gene product from transcript CG12276-RA	0.147
Usp7	ubiquitin-specific protease 7	0.125
fl(2)d	female lethal d	0.119
Dcr-1	Dicer-1	0.115
Patr-1	Protein associated with topo II related - 1	0.109
drd	drop dead	0.100
egg	eggless	0.088
Nipped-B	CG17704 gene product from transcript CG17704-RI	0.087
CG8443	CG8443 gene product from transcript CG8443-RA	0.082
brm	brahma	0.080
Hel25E	Helicase at 25E	0.079
Smox	Smad on X	0.071
MAN1	CG3167 gene product from transcript CG3167-RA	0.069
Sep2	Septin-2	0.067
alpha-Adaptin	CG4260 gene product from transcript CG4260-RA	0.065
Ube3a	Ubiquitin protein ligase E3A	0.063
vfl	vielfaltig	0.061
Snr1	Snf5-related 1	0.060
CG34415	CG34415 gene product from transcript CG34415-RC	0.060
gw	gawky	0.059
Parg	Poly(ADP-ribose) glycohydrolase	0.055
Cbp80	cap binding protein 80	0.053
Fs	Follistatin	0.051
Aac11	CG6582 gene product from transcript CG6582-RA	0.048
king-tubby	king tubby	0.047
e(y)3	enhancer of yellow 3	0.047
CTCF	CG8591 gene product from transcript CG8591-RA	0.045
rin	rasputin	0.045
l(1)G0289	lethal (1) G0289	0.045
CtBP	C-terminal Binding Protein	0.043
moi	modigliani	0.043
Atx2	Ataxin-2	0.042
px	plexus	0.042
wnd	wallenda	0.041
RYBP	Ring and YY1 Binding Protein	0.039
trc	tricornered	0.038
Rat1	CG10354 gene product from transcript CG10354-RA	0.038	Worm
Hrb98DE	Heterogeneous nuclear ribonucleoprotein at 98DE	0.037
koi	klaroid	0.037
Ars2	CG7843 gene product from transcript CG7843-RA	0.036
krz	kurtz	0.033
dlp	dally-like	0.033
Hr4	CG16902 gene product from transcript CG16902-RC	0.032
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.031
mub	mushroom-body expressed	0.030
Lk6	CG17342 gene product from transcript CG17342-RA	0.030
CG4747	CG4747 gene product from transcript CG4747-RB	0.030
zpg	zero population growth	0.029
Ptp61F	Protein tyrosine phosphatase 61F	0.029
kirre	kin of irre	0.028
east	enhanced adult sensory threshold	0.028
U2A	CG1406 gene product from transcript CG1406-RA	0.027
Vps26	Vacuolar protein sorting 26	0.027
Trn	Transportin	0.027
lark	CG8597 gene product from transcript CG8597-RD	0.027	Human
CG34350	CG34350 gene product from transcript CG34350-RA	0.026
CG3773	CG3773 gene product from transcript CG3773-RA	0.025
Tango6	Transport and Golgi organization 6	0.025
ash1	absent, small, or homeotic discs 1	0.025
fax	failed axon connections	0.025
spas	spastin	0.025
atms	antimeros	0.024
nocte	no circadian temperature entrainment	0.024
path	pathetic	0.023
CG10107	CG10107 gene product from transcript CG10107-RA	0.023
da	daughterless	0.023
TER94	CG2331 gene product from transcript CG2331-RA	0.022
CG15440	CG15440 gene product from transcript CG15440-RA	0.022
CG42260	CG42260 gene product from transcript CG42260-RB	0.022
alc	alicorn	0.021
CG9821	CG9821 gene product from transcript CG9821-RB	0.021
Pcaf	CG4107 gene product from transcript CG4107-RA	0.021
CG10289	CG10289 gene product from transcript CG10289-RA	0.020
Eip75B	Ecdysone-induced protein 75B	0.020
Coprox	Coproporphyrinogen oxidase	0.020
Lam	Lamin	0.019
Mlp84B	Muscle LIM protein at 84B	0.019
Ulp1	CG12359 gene product from transcript CG12359-RA	0.019
Hr51	Hormone receptor 51	0.019
lap	like-AP180	0.019
tll	tailless	0.018
CG2875	CG2875 gene product from transcript CG2875-RB	0.018
Sry-beta	Serendipity beta	0.018
Nf-YA	Nuclear factor Y-box A	0.018
Duox	Dual oxidase	0.018
Hsc70Cb	CG6603 gene product from transcript CG6603-RG	0.018
Pc	Polycomb	0.018
CG4936	CG4936 gene product from transcript CG4936-RA	0.018
Taf5	TBP-associated factor 5	0.018
tna	tonalli	0.018
CG17002	CG17002 gene product from transcript CG17002-RB	0.017
fz2	frizzled 2	0.017
glo	glorund	0.017
tatl	tat-like	0.017
Mnt	CG13316 gene product from transcript CG13316-RD	0.017
CG8214	CG8214 gene product from transcript CG8214-RA	0.017
emb	embargoed	0.017
nct	nicastrin	0.017
mago	mago nashi	0.017
CG10741	CG10741 gene product from transcript CG10741-RB	0.017
Bap55	Brahma associated protein 55kD	0.016
Fmr1	CG6203 gene product from transcript CG6203-RC	0.016
Kul	Kuzbanian-like	0.016
CG7757	CG7757 gene product from transcript CG7757-RA	0.016
lmg	lemming	0.016
CG12029	CG12029 gene product from transcript CG12029-RB	0.016
fu2	CG9233 gene product from transcript CG9233-RA	0.016
Nup153	Nucleoporin 153	0.016
Tif-IA	CG3278 gene product from transcript CG3278-RA	0.016
uex	unextended	0.016
Scm	Sex comb on midleg	0.016
chp	chaoptic	0.016
CG2199	CG2199 gene product from transcript CG2199-RB	0.016
spin	spinster	0.015
Irk3	Inwardly rectifying potassium channel 3	0.015
Crag	Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein	0.015
foi	fear-of-intimacy	0.015
CG3918	CG3918 gene product from transcript CG3918-RA	0.015
wls	wntless	0.015
sec5	CG8843 gene product from transcript CG8843-RA	0.015
Gmer	GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase	0.015
Pli	Pellino	0.015
botv	brother of tout-velu	0.015
CG3797	CG3797 gene product from transcript CG3797-RA	0.015
CG1021	CG1021 gene product from transcript CG1021-RE	0.015
org-1	optomotor-blind-related-gene-1	0.015
Sep4	Septin 4	0.015
pico	CG11940 gene product from transcript CG11940-RA	0.015
hrg	hiiragi	0.014
CG8108	CG8108 gene product from transcript CG8108-RA	0.014
simj	simjang	0.014
hiw	highwire	0.014
Roc1a	CG16982 gene product from transcript CG16982-RB	0.014
Clp	Clipper	0.014
Fer2LCH	Ferritin 2 light chain homologue	0.014
wdb	widerborst	0.014
tara	taranis	0.014
E(Pc)	Enhancer of Polycomb	0.013
l(2)03659	lethal (2) 03659	0.013
rump	rumpelstiltskin	0.013
sqd	squid	0.013
Tsp96F	Tetraspanin 96F	0.013
gcl	germ cell-less	0.013
CG16718	CG16718 gene product from transcript CG16718-RA	0.013
Dcp-1	Death caspase-1	0.013
Sox14	Sox box protein 14	0.013
piwi	CG6122 gene product from transcript CG6122-RA	0.013
p47	CG11139 gene product from transcript CG11139-RA	0.013
CycD	Cyclin D	0.013
CG13900	CG13900 gene product from transcript CG13900-RA	0.013
Su(var)3-7	Suppressor of variegation 3-7	0.013
CG4980	CG4980 gene product from transcript CG4980-RA	0.013
CG13933	CG13933 gene product from transcript CG13933-RA	0.013
CG10217	CG10217 gene product from transcript CG10217-RB	0.013
Sry-delta	Serendipity delta	0.013
cln3	CG5582 gene product from transcript CG5582-RA	0.012
scny	scrawny	0.012
Notum	CG13076 gene product from transcript CG13076-RB	0.012
Caf1	Chromatin assembly factor 1 subunit	0.012
Gga	CG3002 gene product from transcript CG3002-RB	0.012
sm	smooth	0.012
Tbh	Tyramine beta hydroxylase	0.012
Tango13	Transport and Golgi organization 13	0.012
row	relative of woc	0.012
r2d2	CG7138 gene product from transcript CG7138-RB	0.012
Rpd3	CG7471 gene product from transcript CG7471-RA	0.012
BRWD3	CG31132 gene product from transcript CG31132-RA	0.012
rno	rhinoceros	0.012
WASp	CG1520 gene product from transcript CG1520-RA	0.012
dysb	dysbindin	0.012
CG14712	CG14712 gene product from transcript CG14712-RA	0.012
Dis3	CG6413 gene product from transcript CG6413-RA	0.011
Clk	Clock	0.011
geminin	CG3183 gene product from transcript CG3183-RA	0.011
sll	slalom	0.011
CG13192	CG13192 gene product from transcript CG13192-RA	0.011
E(var)3-9	Enhancer of variegation 3-9	0.011
mol	moladietz	0.011
rumi	CG31152 gene product from transcript CG31152-RA	0.011
Cul-3	Cullin-3	0.011
Mtor	Megator	0.011
CG9425	CG9425 gene product from transcript CG9425-RB	0.011
NFAT	NFAT homolog	0.011
h	hairy	0.011
CG8435	CG8435 gene product from transcript CG8435-RA	0.011
His2Av	Histone H2A variant	0.011
TfIIS	RNA polymerase II elongation factor	0.011
arr	arrow	0.011
Sir2	CG5216 gene product from transcript CG5216-RA	0.011
Unr	Upstream of N-ras	0.011
boi	brother of iHog	0.011
CG16941	CG16941 gene product from transcript CG16941-RA	0.011
HLH54F	CG5005 gene product from transcript CG5005-RA	0.011
MRG15	CG6363 gene product from transcript CG6363-RA	0.011
CG5451	CG5451 gene product from transcript CG5451-RA	0.011
Ir	Inwardly rectifying potassium channel	0.011
Tre1	trapped in endoderm-1	0.011
bgcn	benign gonial cell neoplasm	0.011
Sulf1	Sulfated	0.011
chinmo	Chronologically inappropriate morphogenesis	0.011
hpo	hippo	0.011
CG4495	CG4495 gene product from transcript CG4495-RA	0.011
vari	varicose	0.011
bchs	blue cheese	0.011
Caps	Calcium activated protein for secretion	0.010
brp	bruchpilot	0.010
CG11148	CG11148 gene product from transcript CG11148-RD	0.010
ird5	immune response deficient 5	0.010
kcc	kazachoc	0.010
Coq2	Coenzyme Q biosynthesis protein 2	0.010
CG5871	CG5871 gene product from transcript CG5871-RA	0.010
CG9733	CG9733 gene product from transcript CG9733-RA	0.010
HLH106	Helix loop helix protein 106	0.010
Sce	Sex combs extra	0.010
CG6933	CG6933 gene product from transcript CG6933-RA	0.010
Rpb4	CG33520 gene product from transcript CG33520-RF	0.010
SuUR	Suppressor of Under-Replication	0.010
CSN6	COP9 complex homolog subunit 6	0.010
ase	asense	0.010
kek5	kekkon5	0.010
CG15255	CG15255 gene product from transcript CG15255-RA	0.010
CG5802	CG5802 gene product from transcript CG5802-RB	0.010
dco	discs overgrown	0.010
CG31860	CG31860 gene product from transcript CG31860-RB	0.010
CG9650	CG9650 gene product from transcript CG9650-RG	0.010
tsr	twinstar	0.010
nej	nejire	0.010
gce	germ cell-expressed bHLH-PAS	0.010
CG7860	CG7860 gene product from transcript CG7860-RA	0.010
Smyd4	SET and MYND domain protein 4	0.010