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Drosophila melanogaster

35 genes annotated in fly

neurotransmitter secretion

The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neurotransmitter secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "neurotransmitter secretion" (in gray)

Name	Description	Probability	Func Analog Organism
GluRIIA	Glutamate receptor IIA	1.000
brp	bruchpilot	0.949
hiw	highwire	0.893
Syt1	Synaptotagmin 1	0.893
Snap25	Synapse protein 25	0.861
wit	wishful thinking	0.846
KaiRIA	CG18039 gene product from transcript CG18039-RA	0.845	Fly
Syx1A	Syntaxin 1A	0.829
Frq2	Frequenin 2	0.823
unc-13	CG2999 gene product from transcript CG2999-RA	0.816
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.778
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.718	Mouse
gbb	glass bottom boat	0.710
dys	dysfusion	0.699
CkIIalpha	Casein kinase II alpha subunit	0.675
unc-104	CG8566 gene product from transcript CG8566-RB	0.667
Syt4	Synaptotagmin 4	0.651
comt	comatose	0.649
faf	fat facets	0.605
Ank2	Ankyrin 2	0.554
Snap	Soluble NSF attachment protein	0.546
Frq1	Frequenin 1	0.466
stj	straightjacket	0.414
CG31146	CG31146 gene product from transcript CG31146-RD	0.410	Rat
scb	scab	0.408
dlg1	discs large 1	0.397
endoA	endophilin A	0.363
par-1	CG8201 gene product from transcript CG8201-RA	0.343
TBPH	CG10327 gene product from transcript CG10327-RC	0.340
Csp	Cysteine string protein	0.331
Nrx-1	Neurexin 1	0.320	Mouse
Smg1	CG32743 gene product from transcript CG32743-RA	0.279
beta-Spec	beta Spectrin	0.267
Vmat	Vesicular monoamine transporter	0.253
lap	like-AP180	0.248
rtGEF	rho-type guanine exchange factor	0.248
sev	sevenless	0.223
Nsf2	NEM-sensitive fusion protein 2	0.218	Fly
AdoR	Adenosine receptor	0.207
VAChT	CG32848 gene product from transcript CG32848-RA	0.195
slo	slowpoke	0.188	Worm
Actbeta	Activin-beta	0.185
Gad1	Glutamic acid decarboxylase 1	0.183
stnA	stoned A	0.174
mth	methuselah	0.173
Dap160	Dynamin associated protein 160	0.172
CG9339	CG9339 gene product from transcript CG9339-RG	0.166
Chc	Clathrin heavy chain	0.154
Rab3	Rab-protein 3	0.142	Mouse
fz2	frizzled 2	0.140
14-3-3zeta	CG17870 gene product from transcript CG17870-RB	0.137
Khc-73	Kinesin-73	0.136
Shab	Shaker cognate b	0.133
tkv	thickveins	0.129
GluRIIB	Glutamate receptor IIB	0.120	Fly
Adar	Adenosine deaminase acting on RNA	0.119
mnb	minibrain	0.117
pAbp	polyA-binding protein	0.113
foxo	forkhead box, sub-group O	0.112
neuroligin	CG13772 gene product from transcript CG13772-RA	0.107	Mouse Rat
Atpalpha	Na pump alpha subunit	0.106
VGlut	Vesicular glutamate transporter	0.105
Abl	Abl tyrosine kinase	0.098
skf	skiff	0.094
jeb	jelly belly	0.092
dnc	dunce	0.090
Amph	Amphiphysin	0.089
rl	rolled	0.082
Imp	IGF-II mRNA-binding protein	0.079
Pde8	Phosphodiesterase 8	0.078
Dab	Disabled	0.075
n-syb	n-synaptobrevin	0.069
TyrR	Tyramine receptor	0.068
Oli	Olig family	0.066
Rab11	Rab-protein 11	0.065
mtt	mangetout	0.065
CG32635	CG32635 gene product from transcript CG32635-RA	0.064
Rya-r44F	Ryanodine receptor 44F	0.062
jar	jaguar	0.062
TER94	CG2331 gene product from transcript CG2331-RA	0.060
CDase	Ceramidase	0.058
Caki	Calcium/calmodulin-dependent protein kinase	0.055
gammaSnap	gamma-soluble NSF attachment protein	0.054
Pgk	Phosphoglycerate kinase	0.052
wun	wunen	0.051
nwk	nervous wreck	0.051
CG15658	CG15658 gene product from transcript CG15658-RA	0.050
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.050
shi	shibire	0.048
stmA	stambha A	0.046
mle	maleless	0.045
Calx	Na/Ca-exchange protein	0.045
Hrs	Hepatocyte growth factor regulated tyrosine kinase substrate	0.045
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.045	Rat
spict	spichthyin	0.044
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.043
bves	CG32513 gene product from transcript CG32513-RA	0.042
Eaat1	Excitatory amino acid transporter 1	0.042
CG12753	CG12753 gene product from transcript CG12753-RB	0.042
GABA-B-R3	metabotropic GABA-B receptor subtype 3	0.042	Fly
G-salpha60A	G protein salpha 60A	0.040
5-HT1B	Serotonin receptor 1B	0.040
bsk	basket	0.040
Ca-alpha1D	Ca[2+]-channel protein alpha[[1]] subunit D	0.039	Fly
Alk	CG8250 gene product from transcript CG8250-RA	0.038
tweek	CG42555 gene product from transcript CG42555-RD	0.037
Dip3	Dorsal interacting protein 3	0.037
Cdk5alpha	Cdk5 activator-like protein	0.037
WASp	CG1520 gene product from transcript CG1520-RA	0.036
fusl	fuseless	0.036
Syn2	Syntrophin-like 2	0.036
Rop	Ras opposite	0.035
mtg	mind the gap	0.034
sif	still life	0.034
nej	nejire	0.032
Octbeta2R	CG33976 gene product from transcript CG33976-RA	0.032
dimm	dimmed	0.031
pum	pumilio	0.031
Lrrk	Leucine-rich repeat kinase	0.031	Human
pdfr	PDF receptor	0.031
CG8959	CG8959 gene product from transcript CG8959-RA	0.030
Jra	Jun-related antigen	0.029
ST6Gal	Sialyltransferase	0.029
GluRIIE	Glutamate receptor IIE	0.029	Fly
nAcRalpha-30D	nicotinic Acetylcholine Receptor alpha 30D	0.029
CG1599	CG1599 gene product from transcript CG1599-RA	0.028
eys	eyes shut	0.028
cac	cacophony	0.028
Syb	Synaptobrevin	0.028	Worm
to	takeout	0.027
ETHR	CG5911 gene product from transcript CG5911-RB	0.027
Fmr1	CG6203 gene product from transcript CG6203-RC	0.027
rhea	CG6831 gene product from transcript CG6831-RA	0.025
HDAC6	CG6170 gene product from transcript CG6170-RA	0.025
betaInt-nu	beta[nu] integrin	0.024
Syx7	Syntaxin 7	0.023
sei	seizure	0.023
Pka-R1	cAMP-dependent protein kinase R1	0.023
Fer2	48 related 2	0.023
Tbh	Tyramine beta hydroxylase	0.023
tomosyn	CG17762 gene product from transcript CG17762-RB	0.023
G-oalpha47A	G protein oalpha 47A	0.023
kcc	kazachoc	0.023
sNPF	short neuropeptide F precursor	0.023
Nf1	Neurofibromin 1	0.023	Mouse
bru-3	bruno-3	0.023
unk	unkempt	0.022
trio	CG18214 gene product from transcript CG18214-RA	0.022
usnp	ubisnap	0.022
CG32206	CG32206 gene product from transcript CG32206-RB	0.022
CG8117	CG8117 gene product from transcript CG8117-RA	0.021
srpk79D	serine-arginine protein kinase at 79D	0.021
gogo	golden goal	0.020
HisCl1	Histamine-gated chloride channel subunit 1	0.020
CG31999	CG31999 gene product from transcript CG31999-RA	0.020
t	tan	0.020
so	sine oculis	0.020
elav	embryonic lethal abnormal vision	0.020
sec8	CG2095 gene product from transcript CG2095-RA	0.020
Glut1	Glucose transporter 1	0.020
Cdc42	CG12530 gene product from transcript CG12530-RA	0.020
CanA-14F	Calcineurin A at 14F	0.019
laza	lazaro	0.019
cv-c	crossveinless c	0.019
alpha-Spec	alpha Spectrin	0.019
Clk	Clock	0.019
Cip4	CG15015 gene product from transcript CG15015-RA	0.019
trpml	transient receptor potential mucolipin	0.019
onecut	CG1922 gene product from transcript CG1922-RA	0.019
ru	roughoid	0.018
Rab5	Rab-protein 5	0.018	Human
CG31998	CG31998 gene product from transcript CG31998-RA	0.018
dpr9	CG33485 gene product from transcript CG33485-RA	0.018
Gr28b	Gustatory receptor 28b	0.018
nAcRalpha-7E	nicotinic Acetylcholine Receptor alpha 7E	0.017
Hip14	Huntingtin-interacting protein 14	0.017
miple	CG1221 gene product from transcript CG1221-RA	0.017
CG15650	CG15650 gene product from transcript CG15650-RA	0.017
Gie	novel GTPase indispensable for equal segregation of chromosomes	0.017
CG43073	CG43073 gene product from transcript CG43073-RF	0.017
ewg	erect wing	0.017
nonA	no on or off transient A	0.016
bdg	bedraggled	0.016
LanB1	CG7123 gene product from transcript CG7123-RA	0.016
CG6765	CG6765 gene product from transcript CG6765-RA	0.016
CG31760	CG31760 gene product from transcript CG31760-RB	0.015
hig	hikaru genki	0.015
Ent2	Equilibrative nucleoside transporter 2	0.015
mthl4	methuselah-like 4	0.015	Fly
CG10176	CG10176 gene product from transcript CG10176-RB	0.015
CG33558	CG33558 gene product from transcript CG33558-RG	0.015
NPFR1	neuropeptide F receptor	0.014
Ilp4	Insulin-like peptide 4	0.014
Pi4KIIalpha	CG2929 gene product from transcript CG2929-RC	0.014
CadN	Cadherin-N	0.014
chb	chromosome bows	0.014
pico	CG11940 gene product from transcript CG11940-RA	0.014
CG8907	CG8907 gene product from transcript CG8907-RA	0.014
CG17321	CG17321 gene product from transcript CG17321-RA	0.014
CG13743	CG13743 gene product from transcript CG13743-RA	0.014
dia	diaphanous	0.014
Sh	Shaker	0.014
Ace	Acetylcholine esterase	0.014
Pis	Phosphatidylinositol synthase	0.013
Rab35	CG9575 gene product from transcript CG9575-RA	0.013
CG3262	CG3262 gene product from transcript CG3262-RD	0.013
CG12344	CG12344 gene product from transcript CG12344-RA	0.013
Pur-alpha	Purine-rich binding protein-alpha	0.013
CG14837	CG14837 gene product from transcript CG14837-RC	0.013
CaMKI	Calcium/calmodulin-dependent protein kinase I	0.013
CG2278	CG2278 gene product from transcript CG2278-RA	0.013
exba	extra bases	0.013
Syx18	Syntaxin 18	0.013
Takr99D	Tachykinin-like receptor at 99D	0.013
CG12187	CG12187 gene product from transcript CG12187-RA	0.013
CG11319	CG11319 gene product from transcript CG11319-RA	0.013
nAcRbeta-96A	nicotinic Acetylcholine Receptor beta 96A	0.012
mr	morula	0.012
E23	Early gene at 23	0.012
CG12688	CG12688 gene product from transcript CG12688-RA	0.012
CG13995	CG13995 gene product from transcript CG13995-RA	0.012
CG31976	CG31976 gene product from transcript CG31976-RB	0.012
Gprk1	G protein-coupled receptor kinase 1	0.012
per	period	0.012
CG9335	CG9335 gene product from transcript CG9335-RA	0.012
Lim3	CG10699 gene product from transcript CG10699-RB	0.012
dpr10	CG32057 gene product from transcript CG32057-RB	0.012
Grip	Glutamate receptor binding protein	0.012
CG33143	CG33143 gene product from transcript CG33143-RC	0.012
GABA-B-R2	metabotropic GABA-B receptor subtype 2	0.012
CG10260	CG10260 gene product from transcript CG10260-RB	0.011
CG13650	CG13650 gene product from transcript CG13650-RB	0.011
CG34400	CG34400 gene product from transcript CG34400-RD	0.011
bou	boudin	0.011
eg	eagle	0.011
MTF-1	Metal response element-binding Transcription Factor-1	0.011
mthl3	methuselah-like 3	0.011	Fly
CG10508	CG10508 gene product from transcript CG10508-RH	0.011
Pdh	Photoreceptor dehydrogenase	0.011
rno	rhinoceros	0.011
sfl	sulfateless	0.011
Fas3	Fasciclin 3	0.011
loco	locomotion defects	0.011
Mlc-c	Myosin light chain cytoplasmic	0.011
Acsl	Acyl-CoA synthetase long-chain	0.011
CG3907	CG3907 gene product from transcript CG3907-RB	0.011
cpx	complexin	0.011
Pvf3	PDGF- and VEGF-related factor 3	0.011
RhoGAP92B	CG4755 gene product from transcript CG4755-RA	0.011
poe	purity of essence	0.011
HERC2	CG11734 gene product from transcript CG11734-RC	0.011
zfh1	Zn finger homeodomain 1	0.011
ksr	kinase suppressor of ras	0.011
Lcch3	Ligand-gated chloride channel homolog 3	0.011
CG3009	CG3009 gene product from transcript CG3009-RA	0.011
CG32544	CG32544 gene product from transcript CG32544-RA	0.011
CG11638	CG11638 gene product from transcript CG11638-RA	0.011
sdt	stardust	0.011
Hsc70-2	Heat shock protein cognate 2	0.011
Ggamma1	G protein gamma 1	0.011
nAcRalpha-80B	nicotinic Acetylcholine Receptor alpha 80B	0.010
CG18538	CG18538 gene product from transcript CG18538-RA	0.010
CG17922	CG17922 gene product from transcript CG17922-RA	0.010
CG8888	CG8888 gene product from transcript CG8888-RA	0.010
CG15356	CG15356 gene product from transcript CG15356-RA	0.010
stg1	stargazin-like protein	0.010
CG14535	CG14535 gene product from transcript CG14535-RA	0.010
E(Pc)	Enhancer of Polycomb	0.010
CG32809	CG32809 gene product from transcript CG32809-RD	0.010
CG15639	CG15639 gene product from transcript CG15639-RA	0.010