IMP

Process View

Drosophila melanogaster

26 genes annotated in fly

positive regulation of endopeptidase activity

Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of endopeptidase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of endopeptidase activity" (in gray)

Name	Description	Probability	Func Analog Organism
th	thread	0.961
Dcp-1	Death caspase-1	0.884	Fly
Nc	Nedd2-like caspase	0.856
rst	roughest	0.826	Fly
alph	alphabet	0.812
CG9772	CG9772 gene product from transcript CG9772-RB	0.798
Dredd	Death related ced-3/Nedd2-like protein	0.780
jar	jaguar	0.740
imd	immune deficiency	0.728
grim	CG4345 gene product from transcript CG4345-RA	0.722
Tbp-1	Tat-binding protein-1	0.657
Rpt1	CG1341 gene product from transcript CG1341-RA	0.650
Pli	Pellino	0.627
Eip74EF	Ecdysone-induced protein 74EF	0.565
BG4	CG12297 gene product from transcript CG12297-RA	0.525
Prosbeta3	Proteasome beta3 subunit	0.480	Yeast
wts	warts	0.460
yuri	yuri gagarin	0.439
Rac1	CG2248 gene product from transcript CG2248-RA	0.423
scrib	scribbled	0.413
hbs	hibris	0.389
bchs	blue cheese	0.376
p53	CG33336 gene product from transcript CG33336-RB	0.373
eyg	eyegone	0.347
RnrL	Ribonucleoside diphosphate reductase large subunit	0.327
X11L	CG5675 gene product from transcript CG5675-RB	0.317
growl	CG14648 gene product from transcript CG14648-RA	0.297
Cyt-c-d	Cytochrome c distal	0.292
Rpt4	CG3455 gene product from transcript CG3455-RA	0.288
Ice	CG7788 gene product from transcript CG7788-RA	0.287
Rpn6	Proteasome p44.5 subunit	0.275
Lasp	CG3849 gene product from transcript CG3849-RB	0.269
betaTub85D	beta-Tubulin at 85D	0.266
CG5384	CG5384 gene product from transcript CG5384-RA	0.255
CG5355	CG5355 gene product from transcript CG5355-RA	0.253
lmg	lemming	0.251
CYLD	cylindromatosis	0.249
sns	sticks and stones	0.237	Fly
W	Wrinkled	0.223
XNP	CG4548 gene product from transcript CG4548-RA	0.215
kirre	kin of irre	0.200	Fly
Trxr-1	Thioredoxin reductase-1	0.192
Ark	Apaf-1-related-killer	0.191
ird5	immune response deficient 5	0.189	Fly
CG3875	CG3875 gene product from transcript CG3875-RA	0.185
CG13364	CG13364 gene product from transcript CG13364-RA	0.185
bon	bonus	0.183
Chro	Chromator	0.181
Gmd	GDP-mannose 4,6-dehydratase	0.163
Mov34	CG3416 gene product from transcript CG3416-RA	0.156
Traf4	TNF-receptor-associated factor 4	0.155
dj	don juan	0.153
ey	eyeless	0.149
disco	disconnected	0.137
B52	CG10851 gene product from transcript CG10851-RB	0.134
stwl	stonewall	0.132
Art4	Arginine methyltransferase 4	0.132
RASSF8	CG5053 gene product from transcript CG5053-RA	0.129
AGO2	Argonaute 2	0.127
Pros26.4	Proteasome 26S subunit subunit 4 ATPase	0.125
Rpn3	Regulatory particle non-ATPase 3	0.118
msl-1	male-specific lethal 1	0.115
edl	ETS-domain lacking	0.115
zfh1	Zn finger homeodomain 1	0.114
pyd	polychaetoid	0.113
flfl	falafel	0.113
msn	misshapen	0.112
Sox14	Sox box protein 14	0.111
Unr	Upstream of N-ras	0.111
Chrac-14	CG13399 gene product from transcript CG13399-RA	0.110
CG7998	CG7998 gene product from transcript CG7998-RA	0.110
hipk	homeodomain interacting protein kinase	0.109
RanGap	Ran GTPase activating protein	0.108
Hr38	Hormone receptor-like in 38	0.106
robo	roundabout	0.105	Human
CG6479	CG6479 gene product from transcript CG6479-RB	0.102
His3.3B	Histone H3.3B	0.099
Pkd2	Polycystic kidney disease gene-2	0.097
park	parkin	0.094
CG10576	CG10576 gene product from transcript CG10576-RA	0.091
nkd	naked cuticle	0.086
CG5731	CG5731 gene product from transcript CG5731-RA	0.085
sty	sprouty	0.083
CG9894	CG9894 gene product from transcript CG9894-RB	0.081
nocte	no circadian temperature entrainment	0.077
CadN	Cadherin-N	0.074
Galpha49B	G protein alpha49B	0.074
Glut1	Glucose transporter 1	0.072
Bsg25D	Blastoderm-specific gene 25D	0.072
mbt	mushroom bodies tiny	0.071
sli	slit	0.071
east	enhanced adult sensory threshold	0.070
hkl	hook-like	0.070
dmt	dalmatian	0.067
key	kenny	0.067
rno	rhinoceros	0.067
rpr	reaper	0.067
CG7033	CG7033 gene product from transcript CG7033-RC	0.066
CG5146	CG5146 gene product from transcript CG5146-RA	0.066
pr-set7	CG3307 gene product from transcript CG3307-RC	0.065
Hsp27	Heat shock protein 27	0.065
Dhod	Dihydroorotate dehydrogenase	0.065
CG1103	CG1103 gene product from transcript CG1103-RA	0.065
mus201	mutagen-sensitive 201	0.065
Pak	PAK-kinase	0.065
wde	windei	0.065
Uba1	Ubiquitin activating enzyme 1	0.064
Df31	Decondensation factor 31	0.063
Arr2	Arrestin 2	0.062	Rat
skl	sickle	0.062
nau	nautilus	0.062
inaD	inactivation no afterpotential D	0.061
CG14683	CG14683 gene product from transcript CG14683-RA	0.060
CG1311	CG1311 gene product from transcript CG1311-RA	0.058
drpr	draper	0.057
Iap2	Inhibitor of apoptosis 2	0.056
CG6412	CG6412 gene product from transcript CG6412-RA	0.055
Rpn9	CG10230 gene product from transcript CG10230-RB	0.055
foi	fear-of-intimacy	0.053
Cks85A	Cyclin-dependent kinase subunit 85A	0.051
PGRP-LC	Peptidoglycan recognition protein LC	0.051
pod1	CG4532 gene product from transcript CG4532-RF	0.050
RpA-70	Replication Protein A 70	0.050
Imp	IGF-II mRNA-binding protein	0.049
chp	chaoptic	0.049
Mst77F	Male-specific transcript 77F	0.048
Rh6	Rhodopsin 6	0.048
lea	leak	0.048	Human
loqs	loquacious	0.048
comm	commissureless	0.048
bor	belphegor	0.048
wnd	wallenda	0.045
zfh2	Zn finger homeodomain 2	0.045
egr	eiger	0.044	Human Mouse
soti	scotti	0.044
oys	oysgedart	0.044
cutlet	CG33122 gene product from transcript CG33122-RA	0.044
frtz	fritz	0.044
gpp	grappa	0.044
pros	prospero	0.043
CG7051	CG7051 gene product from transcript CG7051-RA	0.043
TER94	CG2331 gene product from transcript CG2331-RA	0.043
EndoG	Endonuclease G	0.042
CG5854	CG5854 gene product from transcript CG5854-RA	0.041
dgo	diego	0.040
Rpn1	CG7762 gene product from transcript CG7762-RA	0.040
Sp7	Serine protease 7	0.040
Mcm7	Minichromosome maintenance 7	0.040
cln3	CG5582 gene product from transcript CG5582-RA	0.040
CG8223	CG8223 gene product from transcript CG8223-RA	0.039
btl	breathless	0.039
hep	hemipterous	0.039
ns2	nucleostemin 2	0.039
cindr	CIN85 and CD2AP orthologue	0.039
ninaC	neither inactivation nor afterpotential C	0.039
CG11347	CG11347 gene product from transcript CG11347-RE	0.039
pes	peste	0.039
Tim10	Translocase of inner membrane 10	0.039
topi	matotopetli	0.038
jumu	jumeau	0.038
Pros45	CG1489 gene product from transcript CG1489-RA	0.038
CG7564	CG7564 gene product from transcript CG7564-RA	0.037
CG9384	CG9384 gene product from transcript CG9384-RA	0.037
tna	tonalli	0.037
Vps16A	Vacuolar protein sorting 16A	0.037
Osbp	Oxysterol binding protein	0.036
EfTuM	Elongation factor Tu mitochondrial	0.036
Rab30	CG9100 gene product from transcript CG9100-RB	0.035
CG10638	CG10638 gene product from transcript CG10638-RA	0.035
Kap3	Kinesin associated protein 3	0.035
CG11399	CG11399 gene product from transcript CG11399-RB	0.035
PGRP-LE	Peptidoglycan recognition protein LE	0.035
toy	twin of eyeless	0.035
Roc1b	CG16988 gene product from transcript CG16988-RA	0.034
CG17181	CG17181 gene product from transcript CG17181-RA	0.034
APP-BP1	beta-Amyloid precursor protein binding protein 1	0.034
CG13830	CG13830 gene product from transcript CG13830-RD	0.033
cathD	CG1548 gene product from transcript CG1548-RA	0.033
CG5899	CG5899 gene product from transcript CG5899-RA	0.033
eIF3-S8	CG4954 gene product from transcript CG4954-RA	0.032
alphaTub84B	alpha-Tubulin at 84B	0.032
mus309	mutagen-sensitive 309	0.032
emb	embargoed	0.032
Rpt3	CG16916 gene product from transcript CG16916-RA	0.032
WASp	CG1520 gene product from transcript CG1520-RA	0.032
Rpn2	CG11888 gene product from transcript CG11888-RA	0.032
alphaTub84D	alpha-Tubulin at 84D	0.031
in	inturned	0.031
CG12069	CG12069 gene product from transcript CG12069-RA	0.031
l(2)37Bb	lethal (2) 37Bb	0.031
row	relative of woc	0.031
caz	cabeza	0.030
ran	CG1404 gene product from transcript CG1404-RB	0.030
Hr46	Hormone receptor-like in 46	0.030
Smg5	CG8954 gene product from transcript CG8954-RA	0.029
stan	starry night	0.029
pug	pugilist	0.029
Parp	Poly-(ADP-ribose) polymerase	0.029
Dab	Disabled	0.028
SAK	Sak kinase	0.028
Z600	CG17962 gene product from transcript CG17962-RA	0.028
Socs36E	Suppressor of cytokine signaling at 36E	0.028
CG4030	CG4030 gene product from transcript CG4030-RA	0.027
Mnt	CG13316 gene product from transcript CG13316-RD	0.027
Nup160	Nucleoporin 160	0.027
RecQ5	homolog of RecQ	0.027
unk	unkempt	0.027
RagA	CG11968 gene product from transcript CG11968-RA	0.027
CG12214	CG12214 gene product from transcript CG12214-RB	0.026
nbs	CG6754 gene product from transcript CG6754-RC	0.026
S6k	RPS6-p70-protein kinase	0.026
Cctgamma	CG8977 gene product from transcript CG8977-RC	0.026
CG5155	CG5155 gene product from transcript CG5155-RA	0.026
CG13597	CG13597 gene product from transcript CG13597-RA	0.025
Toll-7	CG8595 gene product from transcript CG8595-RA	0.025
CG5642	CG5642 gene product from transcript CG5642-RA	0.025
CG13090	CG13090 gene product from transcript CG13090-RA	0.025
eIF4E-3	CG8023 gene product from transcript CG8023-RA	0.025
CG10777	CG10777 gene product from transcript CG10777-RB	0.025
Zyx102EF	CG32018 gene product from transcript CG32018-RA	0.025
iHog	interference Hedgehog	0.025
Pros54	Proteasome 54kD subunit	0.025
Hrb87F	Heterogeneous nuclear ribonucleoprotein at 87F	0.025
MED14	Mediator complex subunit 14	0.024
E(bx)	Enhancer of bithorax	0.024
klhl10	CG12423 gene product from transcript CG12423-RB	0.024
NT1	Neurotrophin 1	0.024
l(2)05510	lethal (2) 05510	0.024
ex	expanded	0.024
ago	archipelago	0.024
RpS14a	Ribosomal protein S14a	0.024
wmd	wing morphogenesis defect	0.023
Fdh	Formaldehyde dehydrogenase	0.023
Sod2	Superoxide dismutase 2 (Mn)	0.023
CG10543	CG10543 gene product from transcript CG10543-RA	0.023
rols	rolling pebbles	0.023
burs	bursicon	0.023
Nhe3	Na[+]/H[+] hydrogen exchanger 3	0.023
GckIII	Germinal centre kinase III	0.022
dre4	CG1828 gene product from transcript CG1828-RB	0.022
disp	dispatched	0.022
Ufd1-like	Ubiquitin fusion-degradation 1-like	0.022
Tak1	TGF-beta activated kinase 1	0.022
Rel	Relish	0.022
CG7372	CG7372 gene product from transcript CG7372-RA	0.021
dm	diminutive	0.021
CG6565	CG6565 gene product from transcript CG6565-RA	0.021
CG4857	CG4857 gene product from transcript CG4857-RD	0.021
Ald	Aldolase	0.021
CG3530	CG3530 gene product from transcript CG3530-RC	0.021
Vrp1	Verprolin 1	0.021
kermit	CG11546 gene product from transcript CG11546-RB	0.021
scramb2	scramblase 2	0.021
cnc	cap-n-collar	0.021
lmd	lame duck	0.020
trio	CG18214 gene product from transcript CG18214-RA	0.020
fs(2)ltoPP43	female sterile (2) ltoPP43	0.020
DJ-1alpha	CG6646 gene product from transcript CG6646-RA	0.020
Mer	Merlin	0.020
sw	short wing	0.020
CG5177	CG5177 gene product from transcript CG5177-RA	0.020
CG6783	CG6783 gene product from transcript CG6783-RC	0.020
Prx5	Peroxiredoxin 5	0.020
CG5676	CG5676 gene product from transcript CG5676-RA	0.020
RpL12	Ribosomal protein L12	0.019
Toll-6	CG7250 gene product from transcript CG7250-RA	0.019
CG2469	CG2469 gene product from transcript CG2469-RB	0.019
Vps28	Vacuolar protein sorting 28	0.019
mol	moladietz	0.019
ec	echinus	0.019
Pros35	Proteasome 35kD subunit	0.019
Nap1	Nucleosome assembly protein 1	0.019
tadr	torn and diminished rhabdomeres	0.019
WRNexo	WRN exonuclease	0.018
CG14614	CG14614 gene product from transcript CG14614-RA	0.018
TORC	CG6064 gene product from transcript CG6064-RA	0.018
lok	loki	0.018
CG11267	CG11267 gene product from transcript CG11267-RA	0.018
Atg8a	Autophagy-specific gene 8a	0.018
lola	longitudinals lacking	0.018
chic	chickadee	0.018
alphaTub85E	alpha-Tubulin at 85E	0.018
CG5794	CG5794 gene product from transcript CG5794-RB	0.017
sec8	CG2095 gene product from transcript CG2095-RA	0.017
g	garnet	0.017
betaTub60D	beta-Tubulin at 60D	0.017
Sln	Silnoon	0.017
ru	roughoid	0.017
Atg7	Autophagy-specific gene 7	0.017
rb	ruby	0.017
skpF	CG12227 gene product from transcript CG12227-RA	0.017
trp	transient receptor potential	0.017
CG9090	CG9090 gene product from transcript CG9090-RA	0.017
Snoo	Sno oncogene	0.016
CG2519	CG2519 gene product from transcript CG2519-RB	0.016
Syn2	Syntrophin-like 2	0.016
Ant2	Adenine nucleotide translocase 2	0.016
und	uninitiated	0.016
CG6878	CG6878 gene product from transcript CG6878-RA	0.016
Mtl	Mig-2-like	0.016
ppa	partner of paired	0.016
CG1910	CG1910 gene product from transcript CG1910-RB	0.016
CG11592	CG11592 gene product from transcript CG11592-RA	0.016
CG5017	CG5017 gene product from transcript CG5017-RA	0.016
cactin	CG1676 gene product from transcript CG1676-RA	0.016
mRpS33	mitochondrial ribosomal protein S33	0.016
MICAL-like	CG11259 gene product from transcript CG11259-RA	0.016
Alg-2	Apoptosis-linked gene-2	0.016
porin	CG6647 gene product from transcript CG6647-RA	0.016
eIF3-S9	CG4878 gene product from transcript CG4878-RA	0.016
sr	stripe	0.015
CG3038	CG3038 gene product from transcript CG3038-RB	0.015
Ets65A	Ets at 65A	0.015
bond	james bond	0.015
blow	blown fuse	0.015
HBS1	CG1898 gene product from transcript CG1898-RA	0.015
CHES-1-like	Checkpoint suppressor homologue	0.015
Awh	Arrowhead	0.015
CG10912	CG10912 gene product from transcript CG10912-RA	0.015
stumps	CG31317 gene product from transcript CG31317-RC	0.015
Rac2	CG8556 gene product from transcript CG8556-RA	0.015
r2d2	CG7138 gene product from transcript CG7138-RB	0.015
skpB	CG8881 gene product from transcript CG8881-RA	0.015
Damm	Death associated molecule related to Mch2	0.015
spin	spinster	0.015
RpL7-like	Ribosomal protein L7-like	0.015
spag4	sperm-associated antigen 4	0.014
CG10630	CG10630 gene product from transcript CG10630-RA	0.014
mfrn	mitoferrin	0.014
mge	maggie	0.014
CG4360	CG4360 gene product from transcript CG4360-RA	0.014
repo	reversed polarity	0.014
Ppt1	Palmitoyl-protein thioesterase 1	0.014
Neb-cGP	CG15304 gene product from transcript CG15304-RA	0.014
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.014
CDC45L	CG3658 gene product from transcript CG3658-RA	0.014
CG3223	CG3223 gene product from transcript CG3223-RA	0.014
shg	shotgun	0.014
gro	groucho	0.014
nudC	CG9710 gene product from transcript CG9710-RA	0.014
Psi	P-element somatic inhibitor	0.013
ATP7	CG1886 gene product from transcript CG1886-RB	0.013
Eip93F	CG18389 gene product from transcript CG18389-RB	0.013
sd	scalloped	0.013
fkh	fork head	0.013
shark	Src homology 2, ankyrin repeat, tyrosine kinase	0.013
slv	saliva	0.013
CG5262	CG5262 gene product from transcript CG5262-RA	0.013
Argk	Arginine kinase	0.013
CG6051	CG6051 gene product from transcript CG6051-RB	0.013
CG5741	CG5741 gene product from transcript CG5741-RC	0.013
CG10032	CG10032 gene product from transcript CG10032-RA	0.013
msl-2	male-specific lethal 2	0.013
HtrA2	CG8464 gene product from transcript CG8464-RA	0.013
Cda5	Chitin deacetylase-like 5	0.013
tum	tumbleweed	0.013
Sema-2a	CG4700 gene product from transcript CG4700-RC	0.013
Buffy	CG8238 gene product from transcript CG8238-RA	0.013	Human
vig	vasa intronic gene	0.013
amn	amnesiac	0.013
Cby	Chibby	0.013
santa-maria	scavenger receptor acting in neural tissue and majority of rhodopsin is absent	0.013
Hsp60D	CG16954 gene product from transcript CG16954-RA	0.012
ase	asense	0.012
CG7506	CG7506 gene product from transcript CG7506-RA	0.012
ara	araucan	0.012
Unc-76	CG3981 gene product from transcript CG3981-RB	0.012
Tsp42Ej	Tetraspanin 42Ej	0.012
CG9752	CG9752 gene product from transcript CG9752-RA	0.012
Trap1	CG3152 gene product from transcript CG3152-RA	0.012
Vha100-1	CG1709 gene product from transcript CG1709-RF	0.012
PR2	Fak-like tyrosine kinase	0.012
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.012
CG6404	CG6404 gene product from transcript CG6404-RA	0.012
CG6700	CG6700 gene product from transcript CG6700-RA	0.012
CG9063	CG9063 gene product from transcript CG9063-RA	0.012
Jafrac2	thioredoxin peroxidase 2	0.012
CG1418	CG1418 gene product from transcript CG1418-RA	0.012
mtRNApol	mitochondrial RNA polymerase	0.012
Sema-1b	CG6446 gene product from transcript CG6446-RA	0.012
CG30122	CG30122 gene product from transcript CG30122-RB	0.012
ro	rough	0.012
CG9339	CG9339 gene product from transcript CG9339-RG	0.012
CG16718	CG16718 gene product from transcript CG16718-RA	0.012
Ced-12	CG5336 gene product from transcript CG5336-RA	0.011
Taz	Tafazzin	0.011
Hph	HIF prolyl hydroxylase	0.011
Prosbeta2	Proteasome beta2 subunit	0.011
CG9316	CG9316 gene product from transcript CG9316-RA	0.011
Atg6	Autophagy-specific gene 6	0.011
Gef26	CG9491 gene product from transcript CG9491-RB	0.011
CG2201	CG2201 gene product from transcript CG2201-RA	0.011
RpS4	Ribosomal protein S4	0.011
so	sine oculis	0.011
CG42630	CG42630 gene product from transcript CG42630-RA	0.011
l(1)G0469	lethal (1) G0469	0.011
CG17003	CG17003 gene product from transcript CG17003-RA	0.011
Rpn5	CG1100 gene product from transcript CG1100-RA	0.011
RpL31	Ribosomal protein L31	0.011
fas	faint sausage	0.011
bab1	bric a brac 1	0.011
mRpL55	mitochondrial ribosomal protein L55	0.011
CG8292	CG8292 gene product from transcript CG8292-RA	0.011
Graf	CG8948 gene product from transcript CG8948-RB	0.011
Nmt	N-myristoyl transferase	0.011
Rpn7	CG5378 gene product from transcript CG5378-RA	0.011
gish	gilgamesh	0.011
kuz	kuzbanian	0.011
asf1	anti-silencing factor 1	0.011
AnnX	Annexin X	0.011
CG5902	CG5902 gene product from transcript CG5902-RB	0.011
CG8188	CG8188 gene product from transcript CG8188-RB	0.011
G-ialpha65A	G protein alphai subunit 65A	0.010
Mmp2	Matrix metalloproteinase 2	0.010
ths	thisbe	0.010
fan	farinelli	0.010
CG5916	CG5916 gene product from transcript CG5916-RA	0.010
CG13636	CG13636 gene product from transcript CG13636-RB	0.010
CG32810	CG32810 gene product from transcript CG32810-RB	0.010
Eip78C	Ecdysone-induced protein 78C	0.010
CG15579	CG15579 gene product from transcript CG15579-RA	0.010
CG11638	CG11638 gene product from transcript CG11638-RA	0.010
CG3563	CG3563 gene product from transcript CG3563-RA	0.010
Ctr1B	Copper transporter 1B	0.010
Prosalpha6T	Proteasome alpha6T subunit	0.010
CG4038	CG4038 gene product from transcript CG4038-RA	0.010
LpR1	CG31094 gene product from transcript CG31094-RJ	0.010
Bub3	CG7581 gene product from transcript CG7581-RA	0.010
Nup75	Nucleoporin 75	0.010
CG9940	CG9940 gene product from transcript CG9940-RB	0.010
sip3	septin interacting protein 3	0.010
CG2051	CG2051 gene product from transcript CG2051-RA	0.010
SmE	Small ribonucleoprotein particle protein SmE	0.010