IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

regulation of granzyme b production

GO:0071661

Any process that modulates the frequency, rate, or extent of production of granzyme B.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of granzyme b production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of granzyme b production" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000
IL8	interleukin 8	0.989
IL6	interleukin 6 (interferon, beta 2)	0.950
CCL2	chemokine (C-C motif) ligand 2	0.943	Human
IL1B	interleukin 1, beta	0.928
CCL4	chemokine (C-C motif) ligand 4	0.923	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.908
CXCL10	chemokine (C-X-C motif) ligand 10	0.850
CCL8	chemokine (C-C motif) ligand 8	0.844	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.811
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.801
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.744	Human
IDE	insulin-degrading enzyme	0.708
CXCL9	chemokine (C-X-C motif) ligand 9	0.695
CCL13	chemokine (C-C motif) ligand 13	0.566	Human
CCL20	chemokine (C-C motif) ligand 20	0.533	Human
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.506
DPP4	dipeptidyl-peptidase 4	0.499
ICAM1	intercellular adhesion molecule 1	0.329
CCL22	chemokine (C-C motif) ligand 22	0.267	Human
CD83	CD83 molecule	0.264
CXCL5	chemokine (C-X-C motif) ligand 5	0.198
CCL7	chemokine (C-C motif) ligand 7	0.196	Human
CCL19	chemokine (C-C motif) ligand 19	0.180	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.173
RGS1	regulator of G-protein signaling 1	0.159
SELE	selectin E	0.142
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.140
CXCL13	chemokine (C-X-C motif) ligand 13	0.122
CCR4	chemokine (C-C motif) receptor 4	0.108
VCAM1	vascular cell adhesion molecule 1	0.108
CH25H	cholesterol 25-hydroxylase	0.107
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.103
CCL5	chemokine (C-C motif) ligand 5	0.098	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.095
TRAF1	TNF receptor-associated factor 1	0.095
CCL3	chemokine (C-C motif) ligand 3	0.093	Human
TNF	tumor necrosis factor	0.084
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.077
CCR7	chemokine (C-C motif) receptor 7	0.070
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.070
CCR1	chemokine (C-C motif) receptor 1	0.068
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.065
IL1RN	interleukin 1 receptor antagonist	0.065
IL10	interleukin 10	0.064
DARC	Duffy blood group, chemokine receptor	0.063
CCL11	chemokine (C-C motif) ligand 11	0.060	Human
BIRC3	baculoviral IAP repeat containing 3	0.050
IFNG	interferon, gamma	0.047
BCL2A1	BCL2-related protein A1	0.045
IL7R	interleukin 7 receptor	0.042
ARRB1	arrestin, beta 1	0.036
CD40	CD40 molecule, TNF receptor superfamily member 5	0.036
INHBA	inhibin, beta A	0.036
SOD2	superoxide dismutase 2, mitochondrial	0.035
UBD	ubiquitin D	0.034
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.031
CCL21	chemokine (C-C motif) ligand 21	0.030
OSMR	oncostatin M receptor	0.030
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.030
IL1A	interleukin 1, alpha	0.029
IL1R2	interleukin 1 receptor, type II	0.029
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.028
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.027
GNLY	granulysin	0.027
FPR3	formyl peptide receptor 3	0.026
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.025
MSC	musculin	0.025
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.025
IL32	interleukin 32	0.025
ADAMDEC1	ADAM-like, decysin 1	0.024
CD69	CD69 molecule	0.024
EBI3	Epstein-Barr virus induced 3	0.024
RGS16	regulator of G-protein signaling 16	0.023
SRGN	serglycin	0.023
PLEK	pleckstrin	0.022
SLAMF8	SLAM family member 8	0.022
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.021
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.021
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.020
CSF1	colony stimulating factor 1 (macrophage)	0.019
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.019
C1QA	complement component 1, q subcomponent, A chain	0.019
IL2RB	interleukin 2 receptor, beta	0.019
CXCL12	chemokine (C-X-C motif) ligand 12	0.019
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.019
STAT4	signal transducer and activator of transcription 4	0.018
CCL17	chemokine (C-C motif) ligand 17	0.018	Human
GPR109B	G protein-coupled receptor 109B	0.018
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.017
XCL1	chemokine (C motif) ligand 1	0.017
PI3	peptidase inhibitor 3, skin-derived	0.016
CCL1	chemokine (C-C motif) ligand 1	0.016	Human
CCL23	chemokine (C-C motif) ligand 23	0.015	Human
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.015
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.015
APOC1	apolipoprotein C-I	0.015
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.014
CCR3	chemokine (C-C motif) receptor 3	0.013
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.013
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.013
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.013
IL11	interleukin 11	0.013
PDPN	podoplanin	0.013
NNMT	nicotinamide N-methyltransferase	0.012
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.012
ZC3H12A	zinc finger CCCH-type containing 12A	0.012
IL1R1	interleukin 1 receptor, type I	0.012
CRMP1	collapsin response mediator protein 1	0.012
LRRC32	leucine rich repeat containing 32	0.012
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.012
IL13	interleukin 13	0.012
IL2RA	interleukin 2 receptor, alpha	0.012
CCRL2	chemokine (C-C motif) receptor-like 2	0.011
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.011
PTX3	pentraxin 3, long	0.011
SLAMF7	SLAM family member 7	0.011
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.011
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.011
CD80	CD80 molecule	0.011
PLAUR	plasminogen activator, urokinase receptor	0.011
TM7SF4	transmembrane 7 superfamily member 4	0.011
CCBP2	chemokine binding protein 2	0.010
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.010
IDO1	indoleamine 2,3-dioxygenase 1	0.010
MMP19	matrix metallopeptidase 19	0.010
C2	complement component 2	0.010