IMP

Process View

Homo sapiens

16 genes annotated in human

positive regulation of release of sequestered calcium ion into cytosol

Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of release of sequestered calcium ion into cytosol"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of release of sequestered calcium ion into cytosol" (in gray)

Name	Description	Probability	Func Analog Organism
IL8	interleukin 8	0.999	Human
CCR5	chemokine (C-C motif) receptor 5	0.999	Human
CCL5	chemokine (C-C motif) ligand 5	0.997	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.995	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.979
CCL4	chemokine (C-C motif) ligand 4	0.911	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.904	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.899	Human
IL1B	interleukin 1, beta	0.878
CXCL10	chemokine (C-X-C motif) ligand 10	0.866
CCL20	chemokine (C-C motif) ligand 20	0.853	Human
MPDZ	multiple PDZ domain protein	0.836
IL6	interleukin 6 (interferon, beta 2)	0.781
CCL2	chemokine (C-C motif) ligand 2	0.762	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.745	Human
CCL22	chemokine (C-C motif) ligand 22	0.743	Human
CCL8	chemokine (C-C motif) ligand 8	0.742	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.661
IFNG	interferon, gamma	0.561
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.468
CCL7	chemokine (C-C motif) ligand 7	0.455	Human
CCR2	chemokine (C-C motif) receptor 2	0.436	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.395
TTN	titin	0.331
CCR7	chemokine (C-C motif) receptor 7	0.292	Human
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.284	Human
RGS1	regulator of G-protein signaling 1	0.282
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.278	Human
CCL13	chemokine (C-C motif) ligand 13	0.268	Human
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.251
DPP4	dipeptidyl-peptidase 4	0.250
IL2RB	interleukin 2 receptor, beta	0.247
CCL3	chemokine (C-C motif) ligand 3	0.243	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.225
CXCR3	chemokine (C-X-C motif) receptor 3	0.176
TNF	tumor necrosis factor	0.148
IL10	interleukin 10	0.146
CCR4	chemokine (C-C motif) receptor 4	0.135	Human
CCL19	chemokine (C-C motif) ligand 19	0.125	Human
CLEC7A	C-type lectin domain family 7, member A	0.125
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	0.123
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.122
PSEN2	presenilin 2 (Alzheimer disease 4)	0.113
PTEN	phosphatase and tensin homolog	0.111
BAK1	BCL2-antagonist/killer 1	0.106
CCL11	chemokine (C-C motif) ligand 11	0.094	Human
SOD2	superoxide dismutase 2, mitochondrial	0.093
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.082
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.080
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.075
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.075
GRB2	growth factor receptor-bound protein 2	0.075
CD22	CD22 molecule	0.074
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.073
IRF4	interferon regulatory factor 4	0.070
BCL2A1	BCL2-related protein A1	0.068
IL1R2	interleukin 1 receptor, type II	0.062
SLAMF7	SLAM family member 7	0.057
SH3BP2	SH3-domain binding protein 2	0.056
ALB	albumin	0.056
TRPC3	transient receptor potential cation channel, subfamily C, member 3	0.053	Human
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.052
UBD	ubiquitin D	0.051
PF4	platelet factor 4	0.049	Human
SELE	selectin E	0.049
CXCR6	chemokine (C-X-C motif) receptor 6	0.049	Human
SNCAIP	synuclein, alpha interacting protein	0.045
VCAM1	vascular cell adhesion molecule 1	0.042
CH25H	cholesterol 25-hydroxylase	0.040
SSTR3	somatostatin receptor 3	0.040
CCR3	chemokine (C-C motif) receptor 3	0.039	Human
LAMP3	lysosomal-associated membrane protein 3	0.039
PLEK	pleckstrin	0.039
CXCR5	chemokine (C-X-C motif) receptor 5	0.037	Human
CD83	CD83 molecule	0.035
CCR1	chemokine (C-C motif) receptor 1	0.034	Human
RNR2	l-rRNA	0.034
BCL2L1	BCL2-like 1	0.034
BAD	BCL2-associated agonist of cell death	0.034
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.034
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.033
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.033
CD40LG	CD40 ligand	0.032
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.031	Human
IL18RAP	interleukin 18 receptor accessory protein	0.031
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.031
CXCR2	chemokine (C-X-C motif) receptor 2	0.031	Human
MAPT	microtubule-associated protein tau	0.029
FPR3	formyl peptide receptor 3	0.028
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.028
IL7R	interleukin 7 receptor	0.028
RNF144B	ring finger protein 144B	0.028
AQP9	aquaporin 9	0.028
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.028
IL1A	interleukin 1, alpha	0.028
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.027
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.027
IDO1	indoleamine 2,3-dioxygenase 1	0.027
ADAMDEC1	ADAM-like, decysin 1	0.027
C1orf93	chromosome 1 open reading frame 93	0.025
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.025
SELL	selectin L	0.024
HBA2	hemoglobin, alpha 2	0.024
CAV1	caveolin 1, caveolae protein, 22kDa	0.024
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.024
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.024
PF4V1	platelet factor 4 variant 1	0.023	Human
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.022
IL1F5	interleukin 1 family, member 5 (delta)	0.021
EBI3	Epstein-Barr virus induced 3	0.021
F3	coagulation factor III (thromboplastin, tissue factor)	0.020
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.020
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.020
IL2RG	interleukin 2 receptor, gamma	0.019
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.019
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.019
SPRR2A	small proline-rich protein 2A	0.018
ICAM1	intercellular adhesion molecule 1	0.018
GPR109B	G protein-coupled receptor 109B	0.018
IDE	insulin-degrading enzyme	0.018
OASL	2'-5'-oligoadenylate synthetase-like	0.018
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.018
CLEC10A	C-type lectin domain family 10, member A	0.017
INHBA	inhibin, beta A	0.017
ARRB1	arrestin, beta 1	0.017
CCR6	chemokine (C-C motif) receptor 6	0.016	Human
IL21R	interleukin 21 receptor	0.016
TRPC6	transient receptor potential cation channel, subfamily C, member 6	0.016	Human
TFEC	transcription factor EC	0.016
CXCR1	chemokine (C-X-C motif) receptor 1	0.015	Human
SOCS3	suppressor of cytokine signaling 3	0.015
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.015
CARD11	caspase recruitment domain family, member 11	0.014
SPTBN1	spectrin, beta, non-erythrocytic 1	0.014
C5AR1	complement component 5a receptor 1	0.014
GZMK	granzyme K (granzyme 3; tryptase II)	0.013
CD163	CD163 molecule	0.013
CAV2	caveolin 2	0.013
CCL17	chemokine (C-C motif) ligand 17	0.013	Human
CD79B	CD79b molecule, immunoglobulin-associated beta	0.013
IER3	immediate early response 3	0.013
S100A12	S100 calcium binding protein A12	0.013
ARRDC3	arrestin domain containing 3	0.013
IL18R1	interleukin 18 receptor 1	0.013
WNT2	wingless-type MMTV integration site family member 2	0.013
IL4	interleukin 4	0.013
GPR171	G protein-coupled receptor 171	0.013
CCR9	chemokine (C-C motif) receptor 9	0.013	Human
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.012	Human
DSCAML1	Down syndrome cell adhesion molecule like 1	0.012
CD69	CD69 molecule	0.012
CYTIP	cytohesin 1 interacting protein	0.012
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.012
PI3	peptidase inhibitor 3, skin-derived	0.012
TFPI2	tissue factor pathway inhibitor 2	0.012
IL6R	interleukin 6 receptor	0.012
C2	complement component 2	0.012
KYNU	kynureninase	0.012
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.011
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.011
AIM2	absent in melanoma 2	0.011
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.011
CCL1	chemokine (C-C motif) ligand 1	0.011	Human
LGALS2	lectin, galactoside-binding, soluble, 2	0.010
LAG3	lymphocyte-activation gene 3	0.010
TLR2	toll-like receptor 2	0.010
IL13	interleukin 13	0.010
PTPRE	protein tyrosine phosphatase, receptor type, E	0.010
CSF3	colony stimulating factor 3 (granulocyte)	0.010
DARC	Duffy blood group, chemokine receptor	0.010
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.010
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.010