IMP

Process View

Homo sapiens

14 genes annotated in human

regulation of positive chemotaxis

Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of positive chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of positive chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.947	Human
TEK	TEK tyrosine kinase, endothelial	0.944
EGFR	epidermal growth factor receptor	0.934
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.891	Human
NRP1	neuropilin 1	0.698
CXCL3	chemokine (C-X-C motif) ligand 3	0.690	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.659	Human
DPP4	dipeptidyl-peptidase 4	0.610
VEGFA	vascular endothelial growth factor A	0.545
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.478	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.402	Human
IL8	interleukin 8	0.395
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.390
CAV1	caveolin 1, caveolae protein, 22kDa	0.381
FGA	fibrinogen alpha chain	0.276
DSG2	desmoglein 2	0.261
PLCG1	phospholipase C, gamma 1	0.163
CTNND1	catenin (cadherin-associated protein), delta 1	0.120
CCL20	chemokine (C-C motif) ligand 20	0.106
CDH5	cadherin 5, type 2 (vascular endothelium)	0.092
IL1B	interleukin 1, beta	0.088
FGG	fibrinogen gamma chain	0.088
CXCL11	chemokine (C-X-C motif) ligand 11	0.086	Human
CCR5	chemokine (C-C motif) receptor 5	0.076
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.071	Human
IL6	interleukin 6 (interferon, beta 2)	0.070
PDGFC	platelet derived growth factor C	0.070
ALB	albumin	0.069
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.069
CXCL5	chemokine (C-X-C motif) ligand 5	0.068	Human
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.059
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.055	Human
S100B	S100 calcium binding protein B	0.049
CCR2	chemokine (C-C motif) receptor 2	0.045
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.042	Human
ANGPT1	angiopoietin 1	0.039	Human
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.037
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.037
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.033
NTF4	neurotrophin 4	0.033	Human
COL4A1	collagen, type IV, alpha 1	0.033
CXCL9	chemokine (C-X-C motif) ligand 9	0.030	Human
CCL2	chemokine (C-C motif) ligand 2	0.030
PTPRB	protein tyrosine phosphatase, receptor type, B	0.030
CXCL10	chemokine (C-X-C motif) ligand 10	0.026	Human
ANGPT2	angiopoietin 2	0.025
KITLG	KIT ligand	0.025
PF4	platelet factor 4	0.025
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.024
COL6A1	collagen, type VI, alpha 1	0.024
SH3RF1	SH3 domain containing ring finger 1	0.024
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.023
HDAC6	histone deacetylase 6	0.023
CCL19	chemokine (C-C motif) ligand 19	0.019
PDGFA	platelet-derived growth factor alpha polypeptide	0.019	Human
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.018
CCL8	chemokine (C-C motif) ligand 8	0.018
FLT4	fms-related tyrosine kinase 4	0.018	Human
UBD	ubiquitin D	0.017
VCAM1	vascular cell adhesion molecule 1	0.017
SOD2	superoxide dismutase 2, mitochondrial	0.017
EMD	emerin	0.016
F3	coagulation factor III (thromboplastin, tissue factor)	0.015
BDNF	brain-derived neurotrophic factor	0.015	Human
TTR	transthyretin	0.014
CAV2	caveolin 2	0.014
VEGFC	vascular endothelial growth factor C	0.014
FGFR1	fibroblast growth factor receptor 1	0.013
COL5A1	collagen, type V, alpha 1	0.013
IER3	immediate early response 3	0.013
NTF3	neurotrophin 3	0.013
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.013
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.013
STC1	stanniocalcin 1	0.013
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.013
IFNG	interferon, gamma	0.012
TFPI2	tissue factor pathway inhibitor 2	0.012
CCL5	chemokine (C-C motif) ligand 5	0.012
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.011
DARC	Duffy blood group, chemokine receptor	0.011
CCL7	chemokine (C-C motif) ligand 7	0.011
PECAM1	platelet/endothelial cell adhesion molecule	0.010
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.010
RICTOR	RPTOR independent companion of MTOR, complex 2	0.010
SMAD2	SMAD family member 2	0.010