IMP

Process View

Homo sapiens

39 genes annotated in human

aminoglycan metabolic process

The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "aminoglycan metabolic process"

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Name	Description	Probability	Func Analog Organism
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.987	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.986
FGFR2	fibroblast growth factor receptor 2	0.968
IL1R1	interleukin 1 receptor, type I	0.967
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.947
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.793	Human
TEK	TEK tyrosine kinase, endothelial	0.789
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.758
FGF1	fibroblast growth factor 1 (acidic)	0.544	Human
NRP1	neuropilin 1	0.519
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.512
NUMB	numb homolog (Drosophila)	0.395
HIP1	huntingtin interacting protein 1	0.358
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.323
BCL3	B-cell CLL/lymphoma 3	0.295
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.249
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.219
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.216	Human
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.212
PLCG1	phospholipase C, gamma 1	0.188
FGFR1	fibroblast growth factor receptor 1	0.183
FGA	fibrinogen alpha chain	0.155
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.137
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.123	Rat
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.112
FGF10	fibroblast growth factor 10	0.110	Human
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.099
FGF7	fibroblast growth factor 7	0.092	Human
PDGFC	platelet derived growth factor C	0.088
THBS1	thrombospondin 1	0.086
ENG	endoglin	0.075
APP	amyloid beta (A4) precursor protein	0.074
COL2A1	collagen, type II, alpha 1	0.069
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.067
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.066
EGFR	epidermal growth factor receptor	0.060
FGG	fibrinogen gamma chain	0.058
PLAUR	plasminogen activator, urokinase receptor	0.053
PDGFA	platelet-derived growth factor alpha polypeptide	0.051	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.050
ACSL4	acyl-CoA synthetase long-chain family member 4	0.049
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.048
TNIP2	TNFAIP3 interacting protein 2	0.044
DCN	decorin	0.044	Zebrafish Mouse
IL1R2	interleukin 1 receptor, type II	0.042
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.041
MAN1B1	mannosidase, alpha, class 1B, member 1	0.038
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.037
TGFBR1	transforming growth factor, beta receptor 1	0.037
B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	0.037
USP22	ubiquitin specific peptidase 22	0.036
COL14A1	collagen, type XIV, alpha 1	0.036
CNTF	ciliary neurotrophic factor	0.036
FGF2	fibroblast growth factor 2 (basic)	0.036
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.035
LRRK2	leucine-rich repeat kinase 2	0.034
FSTL1	follistatin-like 1	0.034
TGFB3	transforming growth factor, beta 3	0.034
CAPRIN2	caprin family member 2	0.033
IL8	interleukin 8	0.032
COL5A1	collagen, type V, alpha 1	0.031
TIMP3	TIMP metallopeptidase inhibitor 3	0.030
CCL2	chemokine (C-C motif) ligand 2	0.030
LUM	lumican	0.029
OCRL	oculocerebrorenal syndrome of Lowe	0.029
FNDC3B	fibronectin type III domain containing 3B	0.029
LAMP1	lysosomal-associated membrane protein 1	0.028
BCAR1	breast cancer anti-estrogen resistance 1	0.028
IL1RAP	interleukin 1 receptor accessory protein	0.028
TGFB2	transforming growth factor, beta 2	0.027	Human
PRRX1	paired related homeobox 1	0.027
INHBA	inhibin, beta A	0.027
STC1	stanniocalcin 1	0.027
SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11	0.026
COL1A2	collagen, type I, alpha 2	0.026
FST	follistatin	0.026
DPT	dermatopontin	0.025
PCOLCE	procollagen C-endopeptidase enhancer	0.025
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.025
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.024
IL6	interleukin 6 (interferon, beta 2)	0.023
MBL2	mannose-binding lectin (protein C) 2, soluble	0.022
DDR2	discoidin domain receptor tyrosine kinase 2	0.022
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.022
SKIL	SKI-like oncogene	0.022
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.021
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	0.021
BMP2	bone morphogenetic protein 2	0.021
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.021	Human
NGFR	nerve growth factor receptor	0.020
SDF4	stromal cell derived factor 4	0.020
CHSY1	chondroitin sulfate synthase 1	0.020
PI3	peptidase inhibitor 3, skin-derived	0.020
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.019	Human
ELN	elastin	0.019
ANGPT1	angiopoietin 1	0.019
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	0.019
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.019
FRS2	fibroblast growth factor receptor substrate 2	0.019
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.019
ARMCX3	armadillo repeat containing, X-linked 3	0.019
HTT	huntingtin	0.018
LAMA2	laminin, alpha 2	0.018
SCRG1	stimulator of chondrogenesis 1	0.018
B4GALT7	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)	0.018
SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.018
PID1	phosphotyrosine interaction domain containing 1	0.018
PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	0.018
A1BG	alpha-1-B glycoprotein	0.018
PTPRB	protein tyrosine phosphatase, receptor type, B	0.018
FGFBP1	fibroblast growth factor binding protein 1	0.018
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.018	Rat
VCAN	versican	0.017
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.017
MFAP5	microfibrillar associated protein 5	0.017
CD81	CD81 molecule	0.017
LPPR2	lipid phosphate phosphatase-related protein type 2	0.017
CXCL12	chemokine (C-X-C motif) ligand 12	0.017
TFPI2	tissue factor pathway inhibitor 2	0.017
ANGPT2	angiopoietin 2	0.017	Human
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.017
NOTCH1	notch 1	0.017
JAG1	jagged 1	0.017
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.017
IGF1	insulin-like growth factor 1 (somatomedin C)	0.017	Mouse
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.016
AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.016
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.016
MRC2	mannose receptor, C type 2	0.016
TMEM214	transmembrane protein 214	0.016
CSPG4	chondroitin sulfate proteoglycan 4	0.016
OGN	osteoglycin	0.016
MFAP4	microfibrillar-associated protein 4	0.016	Human
CHPF	chondroitin polymerizing factor	0.016	Human Mouse
A2M	alpha-2-macroglobulin	0.016
DOCK7	dedicator of cytokinesis 7	0.016
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.016
BMX	BMX non-receptor tyrosine kinase	0.016
BCL2A1	BCL2-related protein A1	0.016
ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	0.016
C7	complement component 7	0.016
SLIT2	slit homolog 2 (Drosophila)	0.015
LPAR1	lysophosphatidic acid receptor 1	0.015
WNT3A	wingless-type MMTV integration site family, member 3A	0.015
YIPF2	Yip1 domain family, member 2	0.015
THBS2	thrombospondin 2	0.015
OSMR	oncostatin M receptor	0.015
OMD	osteomodulin	0.015
ZNF431	zinc finger protein 431	0.015
HAS2	hyaluronan synthase 2	0.015
INHBB	inhibin, beta B	0.015
ASPN	asporin	0.015
SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)	0.015
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.015
BICD1	bicaudal D homolog 1 (Drosophila)	0.015
ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6	0.015
GRB7	growth factor receptor-bound protein 7	0.015
CD248	CD248 molecule, endosialin	0.015
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.015
EXTL2	exostoses (multiple)-like 2	0.014
CTSB	cathepsin B	0.014
SLC35B2	solute carrier family 35, member B2	0.014
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.014
PTX3	pentraxin 3, long	0.014
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.014
NME4	non-metastatic cells 4, protein expressed in	0.014
COL6A1	collagen, type VI, alpha 1	0.014
ACVR2B	activin A receptor, type IIB	0.014
CCND2	cyclin D2	0.014
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.014
TREM1	triggering receptor expressed on myeloid cells 1	0.014
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.014
ZDHHC24	zinc finger, DHHC-type containing 24	0.014
ACAN	aggrecan	0.014
GREM1	gremlin 1	0.013
GM2A	GM2 ganglioside activator	0.013
FIGF	c-fos induced growth factor (vascular endothelial growth factor D)	0.013	Human
ZNF358	zinc finger protein 358	0.013
FAM3A	family with sequence similarity 3, member A	0.013
CD163	CD163 molecule	0.013
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.013
FGFR3	fibroblast growth factor receptor 3	0.013
CXCL5	chemokine (C-X-C motif) ligand 5	0.013
CTGF	connective tissue growth factor	0.013
PDPN	podoplanin	0.013
GRINA	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.013
PLXNB3	plexin B3	0.013
BCL10	B-cell CLL/lymphoma 10	0.013
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.013
GAA	glucosidase, alpha; acid	0.013
LZTR1	leucine-zipper-like transcription regulator 1	0.013
CCL20	chemokine (C-C motif) ligand 20	0.013
CCL8	chemokine (C-C motif) ligand 8	0.013
FGB	fibrinogen beta chain	0.013	Human
CPA3	carboxypeptidase A3 (mast cell)	0.013
CLTCL1	clathrin, heavy chain-like 1	0.013
MGP	matrix Gla protein	0.013
CTSA	cathepsin A	0.013
NOV	nephroblastoma overexpressed gene	0.013
CLEC5A	C-type lectin domain family 5, member A	0.013
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.013
CXXC5	CXXC finger protein 5	0.013
PPT1	palmitoyl-protein thioesterase 1	0.013
ADAM9	ADAM metallopeptidase domain 9	0.013
TNIP1	TNFAIP3 interacting protein 1	0.013
IGFBP5	insulin-like growth factor binding protein 5	0.013
G0S2	G0/G1switch 2	0.013
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.013
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.013
C1orf9	chromosome 1 open reading frame 9	0.013
PECAM1	platelet/endothelial cell adhesion molecule	0.012
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.012
FOXF1	forkhead box F1	0.012
HYOU1	hypoxia up-regulated 1	0.012
PYCR1	pyrroline-5-carboxylate reductase 1	0.012
APOD	apolipoprotein D	0.012
SOD3	superoxide dismutase 3, extracellular	0.012
LRP6	low density lipoprotein receptor-related protein 6	0.012	Human
MPG	N-methylpurine-DNA glycosylase	0.012
ATP2C1	ATPase, Ca++ transporting, type 2C, member 1	0.012
ADM	adrenomedullin	0.012
ZEB2	zinc finger E-box binding homeobox 2	0.012
SOAT1	sterol O-acyltransferase 1	0.012
CILP	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	0.012
ACAP2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	0.012
ARG1	arginase, liver	0.012
IL1A	interleukin 1, alpha	0.012	Human
DOK5	docking protein 5	0.012
CHUK	conserved helix-loop-helix ubiquitous kinase	0.012
EPN1	epsin 1	0.012
WNT2	wingless-type MMTV integration site family member 2	0.012
KLF10	Kruppel-like factor 10	0.012
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.012
CALCRL	calcitonin receptor-like	0.012
TMSB4X	thymosin beta 4, X-linked	0.012
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.012
CTSL1	cathepsin L1	0.012
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.012
KLHL5	kelch-like 5 (Drosophila)	0.012
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.012
GMPPA	GDP-mannose pyrophosphorylase A	0.012
EPHA3	EPH receptor A3	0.012
OLFML3	olfactomedin-like 3	0.012
FMO2	flavin containing monooxygenase 2 (non-functional)	0.012
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.012
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.012
MAP2K6	mitogen-activated protein kinase kinase 6	0.012
WISP2	WNT1 inducible signaling pathway protein 2	0.012
DDIT4	DNA-damage-inducible transcript 4	0.012
SSPN	sarcospan (Kras oncogene-associated gene)	0.012
GJA4	gap junction protein, alpha 4, 37kDa	0.012
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.012
TF	transferrin	0.012
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
CCNA1	cyclin A1	0.012
GPR153	G protein-coupled receptor 153	0.011
TMEM100	transmembrane protein 100	0.011
SEP15	15 kDa selenoprotein	0.011
TPST1	tyrosylprotein sulfotransferase 1	0.011
COL4A5	collagen, type IV, alpha 5	0.011
RAB11FIP5	RAB11 family interacting protein 5 (class I)	0.011
SLC39A13	solute carrier family 39 (zinc transporter), member 13	0.011
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.011
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.011
CFHR2	complement factor H-related 2	0.011
ITGB8	integrin, beta 8	0.011
TMEM222	transmembrane protein 222	0.011
IL1F5	interleukin 1 family, member 5 (delta)	0.011
EGFL7	EGF-like-domain, multiple 7	0.011
ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	0.011
MANBA	mannosidase, beta A, lysosomal	0.011
SIL1	SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)	0.011
CAV1	caveolin 1, caveolae protein, 22kDa	0.011
FLT4	fms-related tyrosine kinase 4	0.011
PAMR1	peptidase domain containing associated with muscle regeneration 1	0.011
GLB1	galactosidase, beta 1	0.011
PTPRE	protein tyrosine phosphatase, receptor type, E	0.011
TBC1D9B	TBC1 domain family, member 9B (with GRAM domain)	0.011
WNT5A	wingless-type MMTV integration site family, member 5A	0.011
CD14	CD14 molecule	0.011
DARC	Duffy blood group, chemokine receptor	0.011
LYVE1	lymphatic vessel endothelial hyaluronan receptor 1	0.011	Human Mouse
C1QTNF1	C1q and tumor necrosis factor related protein 1	0.011
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.011
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	0.011
EMILIN1	elastin microfibril interfacer 1	0.011
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.011
IL10	interleukin 10	0.011
LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	0.011
CENPB	centromere protein B, 80kDa	0.011
GPC1	glypican 1	0.011
SOCS3	suppressor of cytokine signaling 3	0.011
CRYAB	crystallin, alpha B	0.011
CA9	carbonic anhydrase IX	0.011
FAM50A	family with sequence similarity 50, member A	0.011
SEZ6L2	seizure related 6 homolog (mouse)-like 2	0.011
HOXD8	homeobox D8	0.011
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.011
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.011
EXT1	exostosin 1	0.010
ATP13A2	ATPase type 13A2	0.010
TGFBR3	transforming growth factor, beta receptor III	0.010
CTSK	cathepsin K	0.010
ALG12	asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)	0.010
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.010
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.010
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.010
PNPLA2	patatin-like phospholipase domain containing 2	0.010
FNDC4	fibronectin type III domain containing 4	0.010
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.010
EDNRB	endothelin receptor type B	0.010
CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1	0.010
ICAM1	intercellular adhesion molecule 1	0.010
ZFPM2	zinc finger protein, multitype 2	0.010
VEGFC	vascular endothelial growth factor C	0.010	Human
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.010
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.010
ACVRL1	activin A receptor type II-like 1	0.010
EMCN	endomucin	0.010
FGF5	fibroblast growth factor 5	0.010
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.010
ABI3BP	ABI family, member 3 (NESH) binding protein	0.010
PLD3	phospholipase D family, member 3	0.010
SIRT6	sirtuin 6	0.010
MOGS	mannosyl-oligosaccharide glucosidase	0.010
SPARCL1	SPARC-like 1 (hevin)	0.010
C16orf58	chromosome 16 open reading frame 58	0.010
EREG	epiregulin	0.010
PFKL	phosphofructokinase, liver	0.010
TGFA	transforming growth factor, alpha	0.010
SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	0.010
EXT2	exostosin 2	0.010
C7orf42	chromosome 7 open reading frame 42	0.010
NAV3	neuron navigator 3	0.010
IGF2	insulin-like growth factor 2 (somatomedin A)	0.010
ARL15	ADP-ribosylation factor-like 15	0.010
NMT2	N-myristoyltransferase 2	0.010
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.010
ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	0.010
GEM	GTP binding protein overexpressed in skeletal muscle	0.010