IMP

Process View

Homo sapiens

21 genes annotated in human

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cellular extravasation

GO:0045123

The migration of a leukocyte from the blood vessels into the surrounding tissue.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular extravasation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular extravasation" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000
FHL2	four and a half LIM domains 2	1.000
FLNA	filamin A, alpha	0.999
FN1	fibronectin 1	0.992
NCF2	neutrophil cytosolic factor 2	0.979
MPZL2	myelin protein zero-like 2	0.948	Human
MPZL3	myelin protein zero-like 3	0.930	Human
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.924	Human
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.920	Human
PDIA3	protein disulfide isomerase family A, member 3	0.874
SELPLG	selectin P ligand	0.872	Mouse
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.855	Human Mouse
ENG	endoglin	0.835
PECAM1	platelet/endothelial cell adhesion molecule	0.819
ITGA6	integrin, alpha 6	0.774	Human
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.731	Human
VCAM1	vascular cell adhesion molecule 1	0.639
PXN	paxillin	0.621
TJP1	tight junction protein 1 (zona occludens 1)	0.596
MSN	moesin	0.565
CCR5	chemokine (C-C motif) receptor 5	0.550
ITGB4	integrin, beta 4	0.533	Human
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.476
BIRC3	baculoviral IAP repeat containing 3	0.468
TBXA2R	thromboxane A2 receptor	0.426	Human
PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	0.417	Human
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.369
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.353
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.244
PTPRC	protein tyrosine phosphatase, receptor type, C	0.236
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.232	Human
ITGB7	integrin, beta 7	0.225
PLEC	plectin	0.219
ICAM1	intercellular adhesion molecule 1	0.207
EPS8	epidermal growth factor receptor pathway substrate 8	0.202
LAPTM5	lysosomal protein transmembrane 5	0.194
DPP4	dipeptidyl-peptidase 4	0.187
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.186
TLN1	talin 1	0.178
ICAM2	intercellular adhesion molecule 2	0.175	Human
FLNB	filamin B, beta	0.165
MYO10	myosin X	0.164
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.162	Zebrafish
FERMT3	fermitin family member 3	0.145
CYTH1	cytohesin 1	0.140
FRS2	fibroblast growth factor receptor substrate 2	0.135
VCL	vinculin	0.117
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.111	Human Mouse Rat
RANBP9	RAN binding protein 9	0.106
RHOA	ras homolog gene family, member A	0.103
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.101	Human
CD63	CD63 molecule	0.096
TSG101	tumor susceptibility gene 101	0.095
TRAF1	TNF receptor-associated factor 1	0.089
ANXA5	annexin A5	0.085
CD9	CD9 molecule	0.080
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.073
FHL3	four and a half LIM domains 3	0.072
SNX20	sorting nexin 20	0.072
ZBP1	Z-DNA binding protein 1	0.066
STK10	serine/threonine kinase 10	0.063
ANGPTL4	angiopoietin-like 4	0.060
PSEN2	presenilin 2 (Alzheimer disease 4)	0.059
LCP1	lymphocyte cytosolic protein 1 (L-plastin)	0.056
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.056
ADAM9	ADAM metallopeptidase domain 9	0.054
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.051
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.051
ITGB5	integrin, beta 5	0.048	Human
DARC	Duffy blood group, chemokine receptor	0.048
CLEC4M	C-type lectin domain family 4, member M	0.047
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.046	Human
THBS1	thrombospondin 1	0.044
IL32	interleukin 32	0.044
IQGAP1	IQ motif containing GTPase activating protein 1	0.042
CCL19	chemokine (C-C motif) ligand 19	0.042
MYO1F	myosin IF	0.041
IL2RG	interleukin 2 receptor, gamma	0.040
TRADD	TNFRSF1A-associated via death domain	0.039
SRGN	serglycin	0.039
VAV1	vav 1 guanine nucleotide exchange factor	0.038
GAB1	GRB2-associated binding protein 1	0.038
COL17A1	collagen, type XVII, alpha 1	0.037
NKG7	natural killer cell group 7 sequence	0.035
CORO1A	coronin, actin binding protein, 1A	0.035
CCL5	chemokine (C-C motif) ligand 5	0.034	Rat
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.034
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.033
ICAM3	intercellular adhesion molecule 3	0.033	Human
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.033
SELL	selectin L	0.033	Human
GMFG	glia maturation factor, gamma	0.032
ITGB1BP1	integrin beta 1 binding protein 1	0.031
HSD3B7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.031
CD34	CD34 molecule	0.031
TRAF3IP3	TRAF3 interacting protein 3	0.031
MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	0.030
PRDX4	peroxiredoxin 4	0.029
IL1B	interleukin 1, beta	0.029
EMCN	endomucin	0.029
DEF6	differentially expressed in FDCP 6 homolog (mouse)	0.029
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.028
CD44	CD44 molecule (Indian blood group)	0.028
CD97	CD97 molecule	0.028
TGFB1	transforming growth factor, beta 1	0.028
CXCR4	chemokine (C-X-C motif) receptor 4	0.027
GHRL	ghrelin/obestatin prepropeptide	0.027
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.026
SELE	selectin E	0.026
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.026
SLAMF7	SLAM family member 7	0.025
ITGA7	integrin, alpha 7	0.023	Human
CFP	complement factor properdin	0.023
CD93	CD93 molecule	0.022
ACVRL1	activin A receptor type II-like 1	0.022
GJA4	gap junction protein, alpha 4, 37kDa	0.022
IL7R	interleukin 7 receptor	0.022
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.022
TM9SF3	transmembrane 9 superfamily member 3	0.022
SLA	Src-like-adaptor	0.022
MYH11	myosin, heavy chain 11, smooth muscle	0.022
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.021
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.021
CYTH4	cytohesin 4	0.021
CCL2	chemokine (C-C motif) ligand 2	0.021
IL10RA	interleukin 10 receptor, alpha	0.020
CST7	cystatin F (leukocystatin)	0.020
MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.019
OSMR	oncostatin M receptor	0.019
PDLIM5	PDZ and LIM domain 5	0.019
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.019
NPNT	nephronectin	0.019
SPTBN1	spectrin, beta, non-erythrocytic 1	0.019
LAMC2	laminin, gamma 2	0.018
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.018
LST1	leukocyte specific transcript 1	0.018
MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.018
LAMB3	laminin, beta 3	0.017
APLNR	apelin receptor	0.017
LMNA	lamin A/C	0.017
CCL20	chemokine (C-C motif) ligand 20	0.017
CAT	catalase	0.017
EVI2B	ecotropic viral integration site 2B	0.017
CLDN5	claudin 5	0.016
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.016
IGF1R	insulin-like growth factor 1 receptor	0.016
CTGF	connective tissue growth factor	0.016
AOAH	acyloxyacyl hydrolase (neutrophil)	0.016
VCAN	versican	0.016
PDZD3	PDZ domain containing 3	0.016
TMC6	transmembrane channel-like 6	0.016
HMHA1	histocompatibility (minor) HA-1	0.015
ALOX5AP	arachidonate 5-lipoxygenase-activating protein	0.015
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.015
LEPR	leptin receptor	0.015
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.015
IQGAP2	IQ motif containing GTPase activating protein 2	0.015
FMNL1	formin-like 1	0.015
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.015
PLEK	pleckstrin	0.014
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.014
IL2RA	interleukin 2 receptor, alpha	0.014
ADAM8	ADAM metallopeptidase domain 8	0.014
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.014
ARHGAP1	Rho GTPase activating protein 1	0.014
SHARPIN	SHANK-associated RH domain interactor	0.014
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.014
GRB2	growth factor receptor-bound protein 2	0.014
CCR7	chemokine (C-C motif) receptor 7	0.014
CYBB	cytochrome b-245, beta polypeptide	0.014
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.014
CCL4	chemokine (C-C motif) ligand 4	0.014
CD52	CD52 molecule	0.014
GNG12	guanine nucleotide binding protein (G protein), gamma 12	0.014
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.013
RAMP3	receptor (G protein-coupled) activity modifying protein 3	0.013
SASH3	SAM and SH3 domain containing 3	0.013
DOCK2	dedicator of cytokinesis 2	0.013
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.013
CCL8	chemokine (C-C motif) ligand 8	0.013
F2RL1	coagulation factor II (thrombin) receptor-like 1	0.012
CD37	CD37 molecule	0.012
MMRN2	multimerin 2	0.012
LIMA1	LIM domain and actin binding 1	0.012
SIPA1	signal-induced proliferation-associated 1	0.012
STAB1	stabilin 1	0.012
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.012
CD83	CD83 molecule	0.012
JAG1	jagged 1	0.012
CD33	CD33 molecule	0.011
IL6	interleukin 6 (interferon, beta 2)	0.011
CLEC1A	C-type lectin domain family 1, member A	0.011
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.011
GPSM3	G-protein signaling modulator 3	0.011
CSF1	colony stimulating factor 1 (macrophage)	0.011
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.011
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.011
CD69	CD69 molecule	0.011
IL2RB	interleukin 2 receptor, beta	0.011
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.011
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.011
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.011
TGFBR1	transforming growth factor, beta receptor 1	0.011
GJA1	gap junction protein, alpha 1, 43kDa	0.011
GJD3	gap junction protein, delta 3, 31.9kDa	0.010
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.010
ACTN4	actinin, alpha 4	0.010
EPHA2	EPH receptor A2	0.010
LAMB1	laminin, beta 1	0.010
FNDC3B	fibronectin type III domain containing 3B	0.010
EZR	ezrin	0.010