IMP

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Homo sapiens

15 genes annotated in human

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ephrin receptor signaling pathway

GO:0048013

The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ephrin receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ephrin receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	1.000
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.998
BCAR1	breast cancer anti-estrogen resistance 1	0.998
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.994
FYN	FYN oncogene related to SRC, FGR, YES	0.984
PTK2	PTK2 protein tyrosine kinase 2	0.969
EGFR	epidermal growth factor receptor	0.959
EPHA2	EPH receptor A2	0.953
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.952
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.948
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.920
GRB2	growth factor receptor-bound protein 2	0.915
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.869	Human
EPHA7	EPH receptor A7	0.710
SFN	stratifin	0.664
STAMBP	STAM binding protein	0.620
EFNA1	ephrin-A1	0.586
GRB10	growth factor receptor-bound protein 10	0.488
GAB1	GRB2-associated binding protein 1	0.482
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.456
ZNF746	zinc finger protein 746	0.422
PXN	paxillin	0.375
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.367
EFNA5	ephrin-A5	0.340
GRB7	growth factor receptor-bound protein 7	0.336
PLCG1	phospholipase C, gamma 1	0.323
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.316
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.305
NCK2	NCK adaptor protein 2	0.236
VAV1	vav 1 guanine nucleotide exchange factor	0.173
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.172
PECAM1	platelet/endothelial cell adhesion molecule	0.171
ATF2	activating transcription factor 2	0.150
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.135
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.131
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.120
NOTCH1	notch 1	0.119
CD33	CD33 molecule	0.110
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.095	Human
FRS2	fibroblast growth factor receptor substrate 2	0.091
EPHB3	EPH receptor B3	0.089
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.088
CAV1	caveolin 1, caveolae protein, 22kDa	0.083
SRCIN1	SRC kinase signaling inhibitor 1	0.080
EPHA3	EPH receptor A3	0.076
TNK2	tyrosine kinase, non-receptor, 2	0.075	Human
ATXN1L	ataxin 1-like	0.071
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.069
SYK	spleen tyrosine kinase	0.062
PILRA	paired immunoglobin-like type 2 receptor alpha	0.062
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.060
MATK	megakaryocyte-associated tyrosine kinase	0.049
SH2D3A	SH2 domain containing 3A	0.047
MAPK14	mitogen-activated protein kinase 14	0.041
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.040
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.034
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.033
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.031
FAM118B	family with sequence similarity 118, member B	0.029
CDK5	cyclin-dependent kinase 5	0.029
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.026
VAV2	vav 2 guanine nucleotide exchange factor	0.026
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.025
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.024
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.024
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.023
NCK1	NCK adaptor protein 1	0.022
TNS4	tensin 4	0.022
FES	feline sarcoma oncogene	0.022
MPZL1	myelin protein zero-like 1	0.021
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.021
IRS1	insulin receptor substrate 1	0.021
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.020
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.019
MAML1	mastermind-like 1 (Drosophila)	0.019
SH3KBP1	SH3-domain kinase binding protein 1	0.019
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.018
PTPRF	protein tyrosine phosphatase, receptor type, F	0.018
DOCK1	dedicator of cytokinesis 1	0.017
TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	0.017
DOK4	docking protein 4	0.016
SPRR2A	small proline-rich protein 2A	0.015
NCOR2	nuclear receptor corepressor 2	0.015
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.015
MUC1	mucin 1, cell surface associated	0.014
JAK2	Janus kinase 2	0.014
PRKCA	protein kinase C, alpha	0.014
EGF	epidermal growth factor	0.013
ERRFI1	ERBB receptor feedback inhibitor 1	0.013
BAIAP2	BAI1-associated protein 2	0.013
TNS3	tensin 3	0.013
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.012
CAV2	caveolin 2	0.012
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.012
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.012
CLTC	clathrin, heavy chain (Hc)	0.012
CIR1	corepressor interacting with RBPJ, 1	0.012
IRS4	insulin receptor substrate 4	0.012
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.012
TMSB4X	thymosin beta 4, X-linked	0.011
EFNB1	ephrin-B1	0.011	Human
KIR2DL1	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	0.011
EPOR	erythropoietin receptor	0.011
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.010
EFS	embryonal Fyn-associated substrate	0.010
CISH	cytokine inducible SH2-containing protein	0.010
GAB2	GRB2-associated binding protein 2	0.010