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Homo sapiens

22 genes annotated in human

dysostosis

DOID:1934

A bone development disease that results in defective ossification of located in bone.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dysostosis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dysostosis" (in gray)

Name	Description	Probability	Func Analog Organism
BMPR1A	bone morphogenetic protein receptor, type IA	1.000	Human
FGF1	fibroblast growth factor 1 (acidic)	0.994
TJP1	tight junction protein 1 (zona occludens 1)	0.966
FSTL1	follistatin-like 1	0.830
BMP2	bone morphogenetic protein 2	0.818
BMPR1B	bone morphogenetic protein receptor, type IB	0.728
FGF10	fibroblast growth factor 10	0.691
FGF2	fibroblast growth factor 2 (basic)	0.547
SETD8	SET domain containing (lysine methyltransferase) 8	0.458
SMAD3	SMAD family member 3	0.327
BMP7	bone morphogenetic protein 7	0.275	Human
GDF5	growth differentiation factor 5	0.271
NOSTRIN	nitric oxide synthase trafficker	0.182
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.167
FGFR1	fibroblast growth factor receptor 1	0.162
NOG	noggin	0.158
FGFR3	fibroblast growth factor receptor 3	0.151	Human
FGF7	fibroblast growth factor 7	0.151
FRS2	fibroblast growth factor receptor substrate 2	0.137
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.125
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.106
SMAD4	SMAD family member 4	0.106
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.095
SKIL	SKI-like oncogene	0.077	Human
C16orf59	chromosome 16 open reading frame 59	0.069
FGFR2	fibroblast growth factor receptor 2	0.067
ZMYND11	zinc finger, MYND-type containing 11	0.065
MSX1	msh homeobox 1	0.061	Human
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.054
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.046
C9orf140	chromosome 9 open reading frame 140	0.041
STK36	serine/threonine kinase 36	0.036
AKAP10	A kinase (PRKA) anchor protein 10	0.034
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.033
ZFYVE9	zinc finger, FYVE domain containing 9	0.031
TROAP	trophinin associated protein (tastin)	0.029
NELL2	NEL-like 2 (chicken)	0.028
CHTF18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.028
E2F2	E2F transcription factor 2	0.026
E2F1	E2F transcription factor 1	0.026
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.023
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.023	Human
STBD1	starch binding domain 1	0.022
POLE	polymerase (DNA directed), epsilon	0.021
HAS2	hyaluronan synthase 2	0.021
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.020
RAD54L	RAD54-like (S. cerevisiae)	0.020
PAQR4	progestin and adipoQ receptor family member IV	0.019
DACH1	dachshund homolog 1 (Drosophila)	0.019
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.019
BMP4	bone morphogenetic protein 4	0.018	Human
STC1	stanniocalcin 1	0.018
GLI2	GLI family zinc finger 2	0.017	Human
AKAP12	A kinase (PRKA) anchor protein 12	0.017
TGFBR1	transforming growth factor, beta receptor 1	0.017	Human
NPTN	neuroplastin	0.017
COL2A1	collagen, type II, alpha 1	0.016
ZBED1	zinc finger, BED-type containing 1	0.015
DOCK9	dedicator of cytokinesis 9	0.015
TONSL	tonsoku-like, DNA repair protein	0.015
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.015
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.014
PLCG1	phospholipase C, gamma 1	0.014
DLX5	distal-less homeobox 5	0.014
C17orf53	chromosome 17 open reading frame 53	0.013
FOXO3	forkhead box O3	0.013
HAND2	heart and neural crest derivatives expressed 2	0.013	Human
FOXF2	forkhead box F2	0.013
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.013
HSPG2	heparan sulfate proteoglycan 2	0.012
INHBA	inhibin, beta A	0.012
KAL1	Kallmann syndrome 1 sequence	0.012
PAM	peptidylglycine alpha-amidating monooxygenase	0.012
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.012
HOXD9	homeobox D9	0.012
MXD3	MAX dimerization protein 3	0.012
PTHLH	parathyroid hormone-like hormone	0.012
HOXD11	homeobox D11	0.012
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.012
WDR62	WD repeat domain 62	0.012
HOXB13	homeobox B13	0.012	Human
PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	0.011	Human
SHB	Src homology 2 domain containing adaptor protein B	0.011
FANCE	Fanconi anemia, complementation group E	0.011
C14orf80	chromosome 14 open reading frame 80	0.011
CTGF	connective tissue growth factor	0.011
FBLN1	fibulin 1	0.011
SERINC3	serine incorporator 3	0.011
SMAD1	SMAD family member 1	0.011
SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	0.011
CHIC2	cysteine-rich hydrophobic domain 2	0.010
CDH13	cadherin 13, H-cadherin (heart)	0.010
LAT	linker for activation of T cells	0.010
TGFB2	transforming growth factor, beta 2	0.010
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.010
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.010
CNTN1	contactin 1	0.010
NCAPH2	non-SMC condensin II complex, subunit H2	0.010
HIPK2	homeodomain interacting protein kinase 2	0.010
TWIST1	twist homolog 1 (Drosophila)	0.008
GLI3	GLI family zinc finger 3	0.006
MSX2	msh homeobox 2	0.006
GJA1	gap junction protein, alpha 1, 43kDa	0.006
HES7	hairy and enhancer of split 7 (Drosophila)	0.006
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.005
HOXD13	homeobox D13	0.004
DLL3	delta-like 3 (Drosophila)	0.004
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.004
PDE4D	phosphodiesterase 4D, cAMP-specific	0.003
IHH	Indian hedgehog	0.002
MESP2	mesoderm posterior 2 homolog (mouse)	0.002
RECQL4	RecQ protein-like 4	0.001
LMBR1	limb region 1 homolog (mouse)	0.001
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.000