Process View
16 genes annotated in human
DOID:2583
A B cell deficiency that is caused by a reduction in all types of gamma globulins.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "agammaglobulinemia"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 1.000 | Human | |
REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.999 | Human | |
CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.964 | ||
BTK | Bruton agammaglobulinemia tyrosine kinase | 0.931 | ||
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.877 | Human | |
CD19 | CD19 molecule | 0.792 | ||
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.461 | ||
CD79B | CD79b molecule, immunoglobulin-associated beta | 0.446 | ||
CD22 | CD22 molecule | 0.412 | ||
BLNK | B-cell linker | 0.322 | ||
RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.246 | Human | |
IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.188 | ||
CDCP1 | CUB domain containing protein 1 | 0.146 | ||
TRIM9 | tripartite motif containing 9 | 0.134 | ||
NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.116 | ||
PRKCB | protein kinase C, beta | 0.089 | ||
NCF1 | neutrophil cytosolic factor 1 | 0.088 | ||
INO80B | INO80 complex subunit B | 0.081 | ||
BCL3 | B-cell CLL/lymphoma 3 | 0.076 | ||
CD9 | CD9 molecule | 0.073 | Human | |
TCL1A | T-cell leukemia/lymphoma 1A | 0.070 | ||
CYBA | cytochrome b-245, alpha polypeptide | 0.049 | ||
SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.042 | ||
SYK | spleen tyrosine kinase | 0.042 | ||
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.041 | ||
MZB1 | marginal zone B and B1 cell-specific protein | 0.040 | ||
CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.037 | ||
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.036 | ||
BLK | B lymphoid tyrosine kinase | 0.036 | Human | |
PNOC | prepronociceptin | 0.034 | ||
TSPAN4 | tetraspanin 4 | 0.034 | ||
VPREB3 | pre-B lymphocyte 3 | 0.033 | ||
POU2AF1 | POU class 2 associating factor 1 | 0.033 | ||
IGL@ | immunoglobulin lambda locus | 0.027 | ||
ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 0.024 | ||
MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.023 | ||
TNIP2 | TNFAIP3 interacting protein 2 | 0.022 | ||
CD72 | CD72 molecule | 0.022 | ||
TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.021 | ||
ZC3H12A | zinc finger CCCH-type containing 12A | 0.021 | ||
FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.020 | ||
FLNA | filamin A, alpha | 0.018 | ||
RHOH | ras homolog gene family, member H | 0.018 | ||
CD99 | CD99 molecule | 0.018 | ||
TNIP1 | TNFAIP3 interacting protein 1 | 0.017 | ||
SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.017 | ||
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.015 | ||
CXCR5 | chemokine (C-X-C motif) receptor 5 | 0.015 | ||
SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.014 | ||
PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.013 | ||
CD2AP | CD2-associated protein | 0.012 | ||
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.012 | ||
SIT1 | signaling threshold regulating transmembrane adaptor 1 | 0.011 | ||
BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.011 | ||
ACTB | actin, beta | 0.011 | ||
CD151 | CD151 molecule (Raph blood group) | 0.010 | ||
IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.008 | ||
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.007 | ||
CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 0.007 | ||
TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B | 0.003 | ||
ICOS | inducible T-cell co-stimulator | 0.003 | ||
LRRC8A | leucine rich repeat containing 8 family, member A | 0.002 | ||
TNFRSF13C | tumor necrosis factor receptor superfamily, member 13C | 0.002 | ||
CD81 | CD81 molecule | 0.001 | ||
LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.001 | ||
PRKCD | protein kinase C, delta | 0.001 | ||
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.000 |