IMP
Process View
Homo sapiens
13 genes annotated in human
human immunodeficiency virus infectious disease
DOID:526
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has material basis in Human immunodeficiency virus 1 or has material basis in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "human immunodeficiency virus infectious disease"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| HLA-G | major histocompatibility complex, class I, G | 0.996 | Human | |
| HLA-A | major histocompatibility complex, class I, A | 0.869 | Human | |
| B2M | beta-2-microglobulin | 0.797 | ||
| HLA-B | major histocompatibility complex, class I, B | 0.763 | ||
| HLA-F | major histocompatibility complex, class I, F | 0.562 | Human | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.527 | ||
| TAPBP | TAP binding protein (tapasin) | 0.427 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.307 | ||
| HLA-E | major histocompatibility complex, class I, E | 0.303 | Human | |
| IL2RG | interleukin 2 receptor, gamma | 0.261 | ||
| IL4 | interleukin 4 | 0.226 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.130 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.076 | Human | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.027 | Human | |
| IL2RB | interleukin 2 receptor, beta | 0.023 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.021 | ||
| CCL8 | chemokine (C-C motif) ligand 8 | 0.020 | Human | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.017 | Human | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.016 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.015 | ||
| BATF2 | basic leucine zipper transcription factor, ATF-like 2 | 0.015 | ||
| CCR4 | chemokine (C-C motif) receptor 4 | 0.014 | Human | |
| IFNG | interferon, gamma | 0.013 | ||
| CCL13 | chemokine (C-C motif) ligand 13 | 0.012 | Human | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.011 | ||
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.011 | ||
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.011 | Human | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.010 | ||
| KIR3DL2 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 | 0.010 | ||
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.010 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.008 | ||
| IL10 | interleukin 10 | 0.007 | ||
| KIR3DL1 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 | 0.003 | ||
| CXCR1 | chemokine (C-X-C motif) receptor 1 | 0.003 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.003 | ||
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.002 | ||
| CD209 | CD209 molecule | 0.002 | ||
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.002 | ||
| TLR3 | toll-like receptor 3 | 0.001 | ||
| IL4R | interleukin 4 receptor | 0.001 | ||
| CCL3L1 | chemokine (C-C motif) ligand 3-like 1 | 0.001 | ||
| HLA-C | major histocompatibility complex, class I, C | 0.000 |