Process View
A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mitotic dna integrity checkpoint"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
RB1 | retinoblastoma 1 | 1.000 | ||
BRCA1 | breast cancer 1, early onset | 1.000 | ||
TP53 | tumor protein p53 | 1.000 | ||
CDK2 | cyclin-dependent kinase 2 | 0.998 | ||
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.997 | ||
XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.995 | ||
PCNA | proliferating cell nuclear antigen | 0.978 | ||
CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.952 | Zebrafish | |
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.891 | ||
E2F1 | E2F transcription factor 1 | 0.882 | ||
HDAC1 | histone deacetylase 1 | 0.824 | ||
COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.820 | Fly | |
PARP1 | poly (ADP-ribose) polymerase 1 | 0.802 | ||
MCM6 | minichromosome maintenance complex component 6 | 0.777 | ||
JUN | jun proto-oncogene | 0.776 | Human | |
SKP2 | S-phase kinase-associated protein 2 (p45) | 0.698 | ||
CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.663 | ||
MCM7 | minichromosome maintenance complex component 7 | 0.657 | Fly | |
PLK1 | polo-like kinase 1 | 0.639 | ||
XIAP | X-linked inhibitor of apoptosis | 0.616 | ||
RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.599 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.587 | ||
RPA1 | replication protein A1, 70kDa | 0.579 | Fly | |
CCNA2 | cyclin A2 | 0.573 | ||
RAD50 | RAD50 homolog (S. cerevisiae) | 0.530 | ||
MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.527 | Human | |
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.517 | ||
PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.496 | ||
TOPBP1 | topoisomerase (DNA) II binding protein 1 | 0.464 | Fly | |
MSH6 | mutS homolog 6 (E. coli) | 0.458 | ||
CUL4A | cullin 4A | 0.452 | ||
HDAC2 | histone deacetylase 2 | 0.448 | ||
XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.440 | ||
CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 0.413 | ||
WRN | Werner syndrome, RecQ helicase-like | 0.404 | ||
MED1 | mediator complex subunit 1 | 0.401 | ||
CDK6 | cyclin-dependent kinase 6 | 0.390 | ||
NBN | nibrin | 0.387 | ||
PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.347 | Human | |
COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.304 | Fly | |
MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.294 | Mouse Fly | |
RBL1 | retinoblastoma-like 1 (p107) | 0.286 | Fly | |
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.284 | Human | |
CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.256 | Fly | |
CCND3 | cyclin D3 | 0.255 | Human | |
CDK8 | cyclin-dependent kinase 8 | 0.254 | Fly | |
CCND1 | cyclin D1 | 0.253 | ||
APAF1 | apoptotic peptidase activating factor 1 | 0.253 | ||
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.245 | ||
BLM | Bloom syndrome, RecQ helicase-like | 0.244 | ||
CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.241 | ||
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.232 | ||
ATM | ataxia telangiectasia mutated | 0.218 | ||
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.218 | Human | |
CUL2 | cullin 2 | 0.207 | ||
CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.197 | ||
SMAD7 | SMAD family member 7 | 0.193 | ||
FAS | Fas (TNF receptor superfamily, member 6) | 0.190 | ||
POLE3 | polymerase (DNA directed), epsilon 3 (p17 subunit) | 0.173 | ||
FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.173 | ||
RPA2 | replication protein A2, 32kDa | 0.168 | ||
RBBP4 | retinoblastoma binding protein 4 | 0.168 | ||
PAX3 | paired box 3 | 0.162 | ||
WWOX | WW domain containing oxidoreductase | 0.160 | ||
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.158 | ||
COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.152 | Fly | |
EME1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.151 | ||
RBBP8 | retinoblastoma binding protein 8 | 0.133 | ||
CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.133 | ||
CASP8AP2 | caspase 8 associated protein 2 | 0.132 | ||
H2AFX | H2A histone family, member X | 0.130 | ||
CCNE1 | cyclin E1 | 0.126 | ||
MCM3 | minichromosome maintenance complex component 3 | 0.125 | Fly | |
UNG | uracil-DNA glycosylase | 0.124 | ||
UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.123 | ||
CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.118 | ||
MCM2 | minichromosome maintenance complex component 2 | 0.117 | ||
CDT1 | chromatin licensing and DNA replication factor 1 | 0.114 | ||
DAXX | death-domain associated protein | 0.112 | ||
BTG1 | B-cell translocation gene 1, anti-proliferative | 0.110 | ||
DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.108 | ||
RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.105 | ||
POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.104 | ||
POU3F2 | POU class 3 homeobox 2 | 0.102 | ||
CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.101 | ||
RBL2 | retinoblastoma-like 2 (p130) | 0.101 | Fly | |
NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.100 | ||
UBXN7 | UBX domain protein 7 | 0.098 | ||
UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.091 | ||
PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.090 | ||
POLD1 | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 0.088 | ||
FADD | Fas (TNFRSF6)-associated via death domain | 0.087 | ||
SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.083 | ||
POU5F1 | POU class 5 homeobox 1 | 0.082 | ||
UBE3A | ubiquitin protein ligase E3A | 0.080 | ||
YAP1 | Yes-associated protein 1 | 0.078 | ||
CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.076 | Fly | |
CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.075 | ||
GPI | glucose-6-phosphate isomerase | 0.074 | ||
TFDP1 | transcription factor Dp-1 | 0.072 | ||
COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.071 | ||
CDC7 | cell division cycle 7 homolog (S. cerevisiae) | 0.071 | ||
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.070 | Human | |
RFWD2 | ring finger and WD repeat domain 2 | 0.070 | ||
MDC1 | mediator of DNA-damage checkpoint 1 | 0.069 | ||
OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.069 | ||
CDK1 | cyclin-dependent kinase 1 | 0.068 | Mouse Fly | |
FEN1 | flap structure-specific endonuclease 1 | 0.067 | ||
EXO1 | exonuclease 1 | 0.067 | ||
TIMELESS | timeless homolog (Drosophila) | 0.065 | ||
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.065 | ||
IER3 | immediate early response 3 | 0.065 | Mouse | |
DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.064 | ||
UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.063 | Fly | |
MED29 | mediator complex subunit 29 | 0.062 | ||
LRDD | leucine-rich repeats and death domain containing | 0.062 | ||
RAD18 | RAD18 homolog (S. cerevisiae) | 0.061 | ||
ORC1 | origin recognition complex, subunit 1 | 0.060 | ||
DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.059 | ||
FANCD2 | Fanconi anemia, complementation group D2 | 0.059 | ||
RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.059 | ||
CCNC | cyclin C | 0.057 | Fly | |
CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.057 | ||
ATF3 | activating transcription factor 3 | 0.057 | ||
ELAVL1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.056 | ||
MED4 | mediator complex subunit 4 | 0.056 | ||
MED23 | mediator complex subunit 23 | 0.054 | ||
MED28 | mediator complex subunit 28 | 0.053 | ||
E2F4 | E2F transcription factor 4, p107/p130-binding | 0.052 | ||
BTBD2 | BTB (POZ) domain containing 2 | 0.052 | ||
E2F2 | E2F transcription factor 2 | 0.051 | ||
CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.050 | ||
CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.049 | Human | |
DTL | denticleless homolog (Drosophila) | 0.049 | Zebrafish | |
BIRC2 | baculoviral IAP repeat containing 2 | 0.049 | ||
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.048 | ||
HIPK2 | homeodomain interacting protein kinase 2 | 0.048 | ||
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.046 | Human | |
NLRC4 | NLR family, CARD domain containing 4 | 0.045 | ||
ORC2 | origin recognition complex, subunit 2 | 0.045 | ||
GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.045 | ||
SLX4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) | 0.044 | ||
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.043 | ||
RAD1 | RAD1 homolog (S. pombe) | 0.043 | ||
CCNB1 | cyclin B1 | 0.043 | ||
CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.043 | ||
ARRB2 | arrestin, beta 2 | 0.043 | ||
ORC3 | origin recognition complex, subunit 3 | 0.042 | ||
MCM4 | minichromosome maintenance complex component 4 | 0.041 | ||
NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.041 | ||
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.041 | ||
MED13 | mediator complex subunit 13 | 0.039 | ||
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.039 | ||
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.038 | ||
BCL2 | B-cell CLL/lymphoma 2 | 0.038 | ||
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.038 | ||
MED13L | mediator complex subunit 13-like | 0.038 | ||
CBX5 | chromobox homolog 5 | 0.036 | ||
TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.036 | Yeast Fly | |
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.036 | ||
SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.035 | ||
MCM10 | minichromosome maintenance complex component 10 | 0.035 | ||
CFLAR | CASP8 and FADD-like apoptosis regulator | 0.035 | ||
TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.034 | ||
RECQL | RecQ protein-like (DNA helicase Q1-like) | 0.034 | ||
SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.034 | ||
MSH2 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 0.033 | Mouse | |
HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.033 | ||
CDK4 | cyclin-dependent kinase 4 | 0.033 | ||
BRCA2 | breast cancer 2, early onset | 0.032 | ||
UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.032 | Yeast | |
ZNF148 | zinc finger protein 148 | 0.032 | ||
CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.031 | ||
CSNK2B | casein kinase 2, beta polypeptide | 0.031 | ||
HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.031 | ||
RFC2 | replication factor C (activator 1) 2, 40kDa | 0.030 | ||
RPL39 | ribosomal protein L39 | 0.030 | ||
VRK1 | vaccinia related kinase 1 | 0.029 | ||
HABP4 | hyaluronan binding protein 4 | 0.029 | ||
RNF20 | ring finger protein 20 | 0.029 | ||
PRMT1 | protein arginine methyltransferase 1 | 0.029 | ||
CCNE2 | cyclin E2 | 0.029 | ||
TELO2 | TEL2, telomere maintenance 2, homolog (S. cerevisiae) | 0.028 | ||
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.028 | ||
BARD1 | BRCA1 associated RING domain 1 | 0.028 | ||
KAT2B | K(lysine) acetyltransferase 2B | 0.028 | ||
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.027 | Human | |
MED18 | mediator complex subunit 18 | 0.026 | ||
E2F3 | E2F transcription factor 3 | 0.026 | ||
PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.026 | ||
ERH | enhancer of rudimentary homolog (Drosophila) | 0.026 | ||
UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.026 | ||
TRIP13 | thyroid hormone receptor interactor 13 | 0.026 | ||
UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.025 | ||
COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.025 | Fly | |
MIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | 0.025 | ||
BBS1 | Bardet-Biedl syndrome 1 | 0.025 | ||
NCL | nucleolin | 0.025 | ||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.025 | ||
SGOL1 | shugoshin-like 1 (S. pombe) | 0.025 | ||
TOP1 | topoisomerase (DNA) I | 0.024 | ||
CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.024 | Human | |
PRMT6 | protein arginine methyltransferase 6 | 0.023 | ||
GMNN | geminin, DNA replication inhibitor | 0.023 | ||
FOXD3 | forkhead box D3 | 0.023 | ||
BRD7 | bromodomain containing 7 | 0.023 | ||
SIRT1 | sirtuin 1 | 0.023 | ||
FANCA | Fanconi anemia, complementation group A | 0.023 | ||
CHAF1B | chromatin assembly factor 1, subunit B (p60) | 0.023 | ||
MYBL2 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | 0.022 | ||
MAPK14 | mitogen-activated protein kinase 14 | 0.022 | ||
FOXM1 | forkhead box M1 | 0.022 | ||
CSNK1A1 | casein kinase 1, alpha 1 | 0.022 | ||
FASLG | Fas ligand (TNF superfamily, member 6) | 0.022 | ||
TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.022 | ||
TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.022 | ||
TRIM28 | tripartite motif containing 28 | 0.022 | ||
USP9X | ubiquitin specific peptidase 9, X-linked | 0.022 | ||
PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.021 | Human | |
RUNX1 | runt-related transcription factor 1 | 0.021 | ||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.021 | ||
COPS7A | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) | 0.021 | Fly | |
ANAPC5 | anaphase promoting complex subunit 5 | 0.021 | ||
CUX1 | cut-like homeobox 1 | 0.020 | ||
BBS2 | Bardet-Biedl syndrome 2 | 0.020 | ||
MED6 | mediator complex subunit 6 | 0.020 | ||
CCND2 | cyclin D2 | 0.020 | Human | |
CCNG1 | cyclin G1 | 0.020 | ||
JUND | jun D proto-oncogene | 0.020 | Human | |
CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.020 | Human | |
IER2 | immediate early response 2 | 0.020 | ||
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.020 | ||
GTSE1 | G-2 and S-phase expressed 1 | 0.020 | ||
TRIM27 | tripartite motif containing 27 | 0.019 | ||
GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.019 | ||
SUMO2 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) | 0.019 | ||
MED26 | mediator complex subunit 26 | 0.019 | ||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.019 | ||
TDG | thymine-DNA glycosylase | 0.019 | ||
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.019 | ||
HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.018 | ||
HDAC4 | histone deacetylase 4 | 0.018 | ||
UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.018 | ||
TP53BP1 | tumor protein p53 binding protein 1 | 0.018 | ||
ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.018 | ||
UBE2G1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.018 | ||
ATR | ataxia telangiectasia and Rad3 related | 0.018 | Fly | |
HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.018 | ||
PMF1 | polyamine-modulated factor 1 | 0.017 | ||
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.017 | ||
RMI1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae) | 0.017 | ||
ANXA4 | annexin A4 | 0.017 | ||
PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.017 | ||
GORAB | golgin, RAB6-interacting | 0.017 | ||
SATB2 | SATB homeobox 2 | 0.017 | ||
IFI16 | interferon, gamma-inducible protein 16 | 0.016 | ||
AGXT2 | alanine--glyoxylate aminotransferase 2 | 0.016 | ||
PIAS2 | protein inhibitor of activated STAT, 2 | 0.016 | ||
EP300 | E1A binding protein p300 | 0.016 | ||
TCF12 | transcription factor 12 | 0.016 | ||
PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.016 | ||
RBM12 | RNA binding motif protein 12 | 0.016 | ||
TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.016 | ||
PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.016 | ||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.015 | ||
CDC45 | cell division cycle 45 homolog (S. cerevisiae) | 0.015 | Fly | |
DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.015 | ||
MKRN1 | makorin ring finger protein 1 | 0.015 | ||
FKBP3 | FK506 binding protein 3, 25kDa | 0.015 | ||
SFN | stratifin | 0.015 | ||
RFC4 | replication factor C (activator 1) 4, 37kDa | 0.015 | ||
POLE2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.015 | ||
TPI1 | triosephosphate isomerase 1 | 0.015 | ||
FOSL1 | FOS-like antigen 1 | 0.015 | ||
CUL5 | cullin 5 | 0.015 | ||
RB1CC1 | RB1-inducible coiled-coil 1 | 0.015 | ||
MTF2 | metal response element binding transcription factor 2 | 0.015 | ||
BIRC3 | baculoviral IAP repeat containing 3 | 0.015 | ||
MNAT1 | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 0.015 | ||
CCNDBP1 | cyclin D-type binding-protein 1 | 0.015 | ||
COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.015 | Fly | |
COPS7B | COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) | 0.015 | ||
PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.015 | ||
WT1 | Wilms tumor 1 | 0.015 | ||
TNRC6B | trinucleotide repeat containing 6B | 0.014 | ||
ATRIP | ATR interacting protein | 0.014 | ||
CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.014 | ||
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.014 | ||
PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.014 | ||
CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 0.014 | ||
JDP2 | Jun dimerization protein 2 | 0.014 | ||
ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.014 | ||
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.014 | ||
DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.014 | ||
DBF4 | DBF4 homolog (S. cerevisiae) | 0.014 | ||
ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.014 | ||
DEK | DEK oncogene | 0.014 | ||
PPP5C | protein phosphatase 5, catalytic subunit | 0.014 | ||
BTBD1 | BTB (POZ) domain containing 1 | 0.013 | ||
CARD11 | caspase recruitment domain family, member 11 | 0.013 | ||
TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.013 | ||
POLR1A | polymerase (RNA) I polypeptide A, 194kDa | 0.013 | ||
TERF2 | telomeric repeat binding factor 2 | 0.013 | ||
EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.013 | ||
OCIAD1 | OCIA domain containing 1 | 0.013 | ||
PRDX2 | peroxiredoxin 2 | 0.013 | ||
POLH | polymerase (DNA directed), eta | 0.013 | ||
HBP1 | HMG-box transcription factor 1 | 0.013 | ||
AHR | aryl hydrocarbon receptor | 0.013 | ||
XPO1 | exportin 1 (CRM1 homolog, yeast) | 0.013 | ||
HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.013 | ||
ORC6 | origin recognition complex, subunit 6 | 0.013 | ||
UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.013 | Yeast | |
TK1 | thymidine kinase 1, soluble | 0.013 | ||
ERCC3 | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 0.013 | ||
TTI1 | Tel2 interacting protein 1 homolog (S. pombe) | 0.013 | ||
GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.013 | ||
UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.013 | ||
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.013 | ||
CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.012 | ||
HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.012 | ||
MASTL | microtubule associated serine/threonine kinase-like | 0.012 | ||
UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.012 | ||
HUS1 | HUS1 checkpoint homolog (S. pombe) | 0.012 | ||
NAP1L1 | nucleosome assembly protein 1-like 1 | 0.012 | ||
ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.012 | ||
METAP2 | methionyl aminopeptidase 2 | 0.012 | ||
B2M | beta-2-microglobulin | 0.012 | ||
LRR1 | leucine rich repeat protein 1 | 0.012 | Worm | |
MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.012 | ||
ANXA1 | annexin A1 | 0.012 | ||
EGR1 | early growth response 1 | 0.012 | ||
SMC1A | structural maintenance of chromosomes 1A | 0.012 | ||
CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) | 0.012 | ||
C19orf2 | chromosome 19 open reading frame 2 | 0.012 | ||
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.012 | ||
CLSPN | claspin | 0.012 | ||
CUL3 | cullin 3 | 0.012 | ||
VHL | von Hippel-Lindau tumor suppressor | 0.012 | ||
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.012 | ||
MCM8 | minichromosome maintenance complex component 8 | 0.012 | ||
USP37 | ubiquitin specific peptidase 37 | 0.012 | ||
E2F5 | E2F transcription factor 5, p130-binding | 0.012 | ||
RAD17 | RAD17 homolog (S. pombe) | 0.012 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.011 | ||
SSRP1 | structure specific recognition protein 1 | 0.011 | ||
PPME1 | protein phosphatase methylesterase 1 | 0.011 | ||
MAPK1 | mitogen-activated protein kinase 1 | 0.011 | ||
BTBD7 | BTB (POZ) domain containing 7 | 0.011 | ||
SATB1 | SATB homeobox 1 | 0.011 | ||
PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.011 | ||
NLK | nemo-like kinase | 0.011 | ||
NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.011 | ||
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.011 | ||
RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.011 | ||
CDCA2 | cell division cycle associated 2 | 0.011 | ||
VEZF1 | vascular endothelial zinc finger 1 | 0.011 | ||
MEOX2 | mesenchyme homeobox 2 | 0.011 | ||
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.011 | ||
PGAM1 | phosphoglycerate mutase 1 (brain) | 0.011 | ||
KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.011 | ||
RECQL4 | RecQ protein-like 4 | 0.011 | ||
FBXO5 | F-box protein 5 | 0.011 | ||
MTA1 | metastasis associated 1 | 0.011 | ||
MCM5 | minichromosome maintenance complex component 5 | 0.011 | ||
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 0.011 | ||
HSF2 | heat shock transcription factor 2 | 0.011 | ||
RBBP7 | retinoblastoma binding protein 7 | 0.011 | ||
RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.011 | ||
JUNB | jun B proto-oncogene | 0.010 | Human | |
MARCKSL1 | MARCKS-like 1 | 0.010 | ||
SMC4 | structural maintenance of chromosomes 4 | 0.010 | ||
BHLHE40 | basic helix-loop-helix family, member e40 | 0.010 | ||
MEN1 | multiple endocrine neoplasia I | 0.010 | ||
BRWD3 | bromodomain and WD repeat domain containing 3 | 0.010 | ||
TUBB | tubulin, beta | 0.010 | ||
STX5 | syntaxin 5 | 0.010 | ||
UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.010 | ||
RYBP | RING1 and YY1 binding protein | 0.010 | ||
H3F3A | H3 histone, family 3A | 0.010 | ||
CCNA1 | cyclin A1 | 0.010 | ||
MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | 0.010 |