IMP

Process View

Homo sapiens

1 genes annotated in human

granzyme b production

The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "granzyme b production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "granzyme b production" (in gray)

Name	Description	Probability	Func Analog Organism
CCL4	chemokine (C-C motif) ligand 4	0.997	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.988
CCL5	chemokine (C-C motif) ligand 5	0.950	Human
IL8	interleukin 8	0.937
CCR5	chemokine (C-C motif) receptor 5	0.921
DPP4	dipeptidyl-peptidase 4	0.920
CXCL11	chemokine (C-X-C motif) ligand 11	0.906
CXCL2	chemokine (C-X-C motif) ligand 2	0.886
CCL2	chemokine (C-C motif) ligand 2	0.883	Human
CCL22	chemokine (C-C motif) ligand 22	0.882	Human
IDE	insulin-degrading enzyme	0.872
CXCL10	chemokine (C-X-C motif) ligand 10	0.869
CCL13	chemokine (C-C motif) ligand 13	0.863	Human
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.828	Human
CCL8	chemokine (C-C motif) ligand 8	0.814	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.725
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.657
ICAM1	intercellular adhesion molecule 1	0.650
IL1B	interleukin 1, beta	0.649
IL6	interleukin 6 (interferon, beta 2)	0.556
CCR1	chemokine (C-C motif) receptor 1	0.529
CCL3	chemokine (C-C motif) ligand 3	0.517	Human
CCL7	chemokine (C-C motif) ligand 7	0.509	Human
CD83	CD83 molecule	0.426
IFNG	interferon, gamma	0.342
CXCL13	chemokine (C-X-C motif) ligand 13	0.326
CCR4	chemokine (C-C motif) receptor 4	0.315
IL7R	interleukin 7 receptor	0.304
IL10	interleukin 10	0.287
VCAM1	vascular cell adhesion molecule 1	0.270
SELE	selectin E	0.255
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.241
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.229
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.221
CCL11	chemokine (C-C motif) ligand 11	0.164	Human
CCL19	chemokine (C-C motif) ligand 19	0.159	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.148
FPR3	formyl peptide receptor 3	0.145
STAT4	signal transducer and activator of transcription 4	0.144
TNF	tumor necrosis factor	0.142
CXCL5	chemokine (C-X-C motif) ligand 5	0.137
UBD	ubiquitin D	0.123
TRAF1	TNF receptor-associated factor 1	0.121
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.114
RGS1	regulator of G-protein signaling 1	0.101
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.095
CCR7	chemokine (C-C motif) receptor 7	0.090
CCL20	chemokine (C-C motif) ligand 20	0.090	Human
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.089
IL2RB	interleukin 2 receptor, beta	0.081
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.081
CH25H	cholesterol 25-hydroxylase	0.071
DARC	Duffy blood group, chemokine receptor	0.066
ARRB1	arrestin, beta 1	0.063
EBI3	Epstein-Barr virus induced 3	0.063
IDO1	indoleamine 2,3-dioxygenase 1	0.062
IL2RG	interleukin 2 receptor, gamma	0.061
LAMP3	lysosomal-associated membrane protein 3	0.058
CD80	CD80 molecule	0.053
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.052
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.051
C1QA	complement component 1, q subcomponent, A chain	0.050
CD40	CD40 molecule, TNF receptor superfamily member 5	0.049
CCR3	chemokine (C-C motif) receptor 3	0.047
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.045
GNLY	granulysin	0.045
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.045
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.043
CXCR6	chemokine (C-X-C motif) receptor 6	0.041
IL1A	interleukin 1, alpha	0.039
SLAMF8	SLAM family member 8	0.038
CCL21	chemokine (C-C motif) ligand 21	0.035
IL18RAP	interleukin 18 receptor accessory protein	0.033
ADAMDEC1	ADAM-like, decysin 1	0.033
MSC	musculin	0.032
CCL17	chemokine (C-C motif) ligand 17	0.030	Human
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.029
C1QB	complement component 1, q subcomponent, B chain	0.029
IL1RN	interleukin 1 receptor antagonist	0.027
NNMT	nicotinamide N-methyltransferase	0.025
RGS16	regulator of G-protein signaling 16	0.024
SLAMF7	SLAM family member 7	0.024
BATF	basic leucine zipper transcription factor, ATF-like	0.024
BIRC3	baculoviral IAP repeat containing 3	0.024
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.024
XCL1	chemokine (C motif) ligand 1	0.024
SLAMF1	signaling lymphocytic activation molecule family member 1	0.023
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.023
DNASE1L3	deoxyribonuclease I-like 3	0.023
C2	complement component 2	0.023
IL1R2	interleukin 1 receptor, type II	0.022
CCL23	chemokine (C-C motif) ligand 23	0.022	Human
CCL1	chemokine (C-C motif) ligand 1	0.022	Human
XCL2	chemokine (C motif) ligand 2	0.022	Human
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.021
CD69	CD69 molecule	0.021
IL13	interleukin 13	0.021
IL2RA	interleukin 2 receptor, alpha	0.020
IL32	interleukin 32	0.019
APOC1	apolipoprotein C-I	0.019
ZC3H12A	zinc finger CCCH-type containing 12A	0.019
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.019
IL21R	interleukin 21 receptor	0.018
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.018
CSF1	colony stimulating factor 1 (macrophage)	0.018
TM7SF4	transmembrane 7 superfamily member 4	0.018
BCL2A1	BCL2-related protein A1	0.018
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.018
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.017
CD209	CD209 molecule	0.017
C1QC	complement component 1, q subcomponent, C chain	0.017
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.016
CCBP2	chemokine binding protein 2	0.016
INHBA	inhibin, beta A	0.016
CCRL2	chemokine (C-C motif) receptor-like 2	0.015
IRF4	interferon regulatory factor 4	0.015
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.014
PRDM1	PR domain containing 1, with ZNF domain	0.014
MARCO	macrophage receptor with collagenous structure	0.013
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.012
PLA2G2D	phospholipase A2, group IID	0.012
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.012
IL10RA	interleukin 10 receptor, alpha	0.012
LAG3	lymphocyte-activation gene 3	0.012
OASL	2'-5'-oligoadenylate synthetase-like	0.012
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.012
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.011
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.011
CLEC10A	C-type lectin domain family 10, member A	0.011
PLA1A	phospholipase A1 member A	0.011
CXCR3	chemokine (C-X-C motif) receptor 3	0.010
CHIT1	chitinase 1 (chitotriosidase)	0.010
ACP5	acid phosphatase 5, tartrate resistant	0.010
TNIP3	TNFAIP3 interacting protein 3	0.010
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.010