Process View
The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "modification dependent macromolecule catabolic process"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
UBC | ubiquitin C | 1.000 | ||
UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 1.000 | ||
RNF11 | ring finger protein 11 | 1.000 | ||
PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 1.000 | Yeast Worm | |
VCP | valosin containing protein | 1.000 | ||
PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 1.000 | Yeast | |
SMAD2 | SMAD family member 2 | 1.000 | Human | |
CUL3 | cullin 3 | 1.000 | ||
PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 1.000 | Yeast | |
PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 1.000 | Yeast | |
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 1.000 | ||
TP53 | tumor protein p53 | 1.000 | ||
UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 1.000 | Human Yeast | |
PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.999 | Yeast | |
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.999 | ||
SKP1 | S-phase kinase-associated protein 1 | 0.999 | ||
UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.999 | Mouse | |
COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.998 | Fly | |
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.998 | ||
CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.998 | ||
RB1 | retinoblastoma 1 | 0.998 | ||
CUL1 | cullin 1 | 0.998 | ||
PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.997 | Yeast Fly | |
PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.997 | Yeast | |
BTRC | beta-transducin repeat containing | 0.997 | ||
FBXW11 | F-box and WD repeat domain containing 11 | 0.996 | ||
PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.995 | Yeast | |
PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.994 | Yeast | |
CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.992 | ||
PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.991 | Yeast | |
SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.991 | ||
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.991 | ||
RNF111 | ring finger protein 111 | 0.991 | Mouse | |
RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.990 | ||
PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 0.990 | ||
PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.990 | Yeast | |
XIAP | X-linked inhibitor of apoptosis | 0.990 | Human | |
HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.990 | Yeast | |
UBQLN1 | ubiquilin 1 | 0.989 | Human | |
RNF5 | ring finger protein 5 | 0.989 | ||
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.988 | ||
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.986 | ||
PLK1 | polo-like kinase 1 | 0.986 | ||
PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.982 | ||
SMAD4 | SMAD family member 4 | 0.978 | Human | |
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.978 | ||
PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.975 | ||
CUL2 | cullin 2 | 0.973 | Worm | |
PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.973 | Yeast | |
ARIH2 | ariadne homolog 2 (Drosophila) | 0.970 | ||
PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.968 | Yeast | |
SKP2 | S-phase kinase-associated protein 2 (p45) | 0.967 | Mouse | |
UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.966 | ||
BRCA1 | breast cancer 1, early onset | 0.966 | ||
EXOSC3 | exosome component 3 | 0.965 | Yeast | |
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.965 | ||
TRAF6 | TNF receptor-associated factor 6 | 0.963 | ||
BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.961 | Mouse Fly | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.961 | Human Mouse | |
POMP | proteasome maturation protein | 0.959 | ||
PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.955 | ||
UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.953 | ||
CCNB1 | cyclin B1 | 0.952 | ||
STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.948 | ||
ZNRF1 | zinc and ring finger 1 | 0.945 | Mouse | |
PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.942 | Yeast | |
UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.939 | Worm | |
SMAD7 | SMAD family member 7 | 0.938 | ||
TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.935 | ||
TRIM39 | tripartite motif containing 39 | 0.930 | ||
PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.928 | Yeast | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.926 | ||
MARCH7 | membrane-associated ring finger (C3HC4) 7 | 0.925 | ||
PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.921 | Yeast | |
MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.914 | Human | |
CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.913 | Fly | |
PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.912 | Yeast | |
PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.909 | ||
ANAPC11 | anaphase promoting complex subunit 11 | 0.902 | Yeast | |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.893 | ||
SMAD5 | SMAD family member 5 | 0.890 | Human | |
HDAC1 | histone deacetylase 1 | 0.889 | ||
GSK3B | glycogen synthase kinase 3 beta | 0.884 | Mouse Fly | |
CCNA2 | cyclin A2 | 0.883 | ||
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.883 | ||
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.876 | ||
AMFR | autocrine motility factor receptor | 0.875 | ||
YY1 | YY1 transcription factor | 0.866 | ||
DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.866 | ||
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.864 | ||
PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.859 | Yeast | |
CDK2 | cyclin-dependent kinase 2 | 0.849 | ||
TRIM43 | tripartite motif containing 43 | 0.834 | ||
PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.832 | Zebrafish | |
OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.832 | ||
FAF2 | Fas associated factor family member 2 | 0.832 | ||
UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.830 | Rat | |
ANAPC4 | anaphase promoting complex subunit 4 | 0.830 | ||
HSPA8 | heat shock 70kDa protein 8 | 0.829 | ||
FBXW7 | F-box and WD repeat domain containing 7 | 0.820 | ||
ANAPC7 | anaphase promoting complex subunit 7 | 0.817 | ||
PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.817 | Yeast | |
FBXO5 | F-box protein 5 | 0.809 | ||
PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.808 | ||
ACTB | actin, beta | 0.805 | ||
RAD23B | RAD23 homolog B (S. cerevisiae) | 0.804 | ||
EP300 | E1A binding protein p300 | 0.802 | ||
PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.801 | Yeast Mouse | |
RFWD2 | ring finger and WD repeat domain 2 | 0.785 | ||
RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.783 | ||
BIRC2 | baculoviral IAP repeat containing 2 | 0.774 | ||
FBXW2 | F-box and WD repeat domain containing 2 | 0.774 | ||
PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.772 | ||
DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.771 | ||
PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.771 | ||
PJA2 | praja ring finger 2 | 0.769 | ||
UBXN7 | UBX domain protein 7 | 0.766 | Yeast | |
CUL5 | cullin 5 | 0.766 | ||
TRIM21 | tripartite motif containing 21 | 0.762 | Human | |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.762 | ||
KLHL12 | kelch-like 12 (Drosophila) | 0.749 | Human | |
HUWE1 | HECT, UBA and WWE domain containing 1 | 0.747 | Human Yeast | |
ATXN3 | ataxin 3 | 0.746 | Mouse | |
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.744 | ||
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.739 | ||
RYBP | RING1 and YY1 binding protein | 0.735 | Fly | |
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.716 | ||
DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.716 | Human | |
EXOSC7 | exosome component 7 | 0.714 | Yeast | |
DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.706 | ||
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.697 | ||
AXIN1 | axin 1 | 0.695 | Mouse Rat | |
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.691 | ||
PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.688 | ||
UBE2E2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | 0.681 | ||
SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.677 | ||
HDAC2 | histone deacetylase 2 | 0.671 | ||
SUMO1 | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 0.668 | ||
CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.668 | Yeast Fly | |
CUL4A | cullin 4A | 0.665 | Mouse | |
UBXN1 | UBX domain protein 1 | 0.660 | ||
ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.659 | Human Mouse Fly | |
ZMYND11 | zinc finger, MYND-type containing 11 | 0.659 | ||
CSNK1A1 | casein kinase 1, alpha 1 | 0.657 | Fly | |
BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.652 | Worm Fly | |
PPP5C | protein phosphatase 5, catalytic subunit | 0.651 | ||
HSPA4 | heat shock 70kDa protein 4 | 0.648 | ||
DIS3L | DIS3 mitotic control homolog (S. cerevisiae)-like | 0.648 | ||
TADA3 | transcriptional adaptor 3 | 0.647 | ||
RBL2 | retinoblastoma-like 2 (p130) | 0.647 | Human | |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.642 | Mouse | |
ARRB1 | arrestin, beta 1 | 0.642 | ||
CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.624 | ||
ANKRD17 | ankyrin repeat domain 17 | 0.622 | ||
USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.622 | ||
CSNK1E | casein kinase 1, epsilon | 0.622 | Mouse Fly | |
ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.621 | ||
RNF14 | ring finger protein 14 | 0.618 | ||
STAG1 | stromal antigen 1 | 0.618 | ||
UBE2E1 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 0.611 | ||
SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.609 | ||
SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | 0.607 | ||
PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.606 | Yeast | |
EXOSC2 | exosome component 2 | 0.603 | Yeast | |
SMAD3 | SMAD family member 3 | 0.594 | Human | |
UBE2H | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | 0.585 | Yeast Mouse | |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.581 | ||
PRKCA | protein kinase C, alpha | 0.577 | ||
CHD4 | chromodomain helicase DNA binding protein 4 | 0.566 | ||
ADRM1 | adhesion regulating molecule 1 | 0.564 | ||
UBE2L3 | ubiquitin-conjugating enzyme E2L 3 | 0.558 | ||
MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.553 | ||
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.552 | ||
FBXO7 | F-box protein 7 | 0.550 | ||
RNF20 | ring finger protein 20 | 0.549 | ||
EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.548 | ||
PDCD6IP | programmed cell death 6 interacting protein | 0.542 | ||
NCF1 | neutrophil cytosolic factor 1 | 0.538 | ||
CREBBP | CREB binding protein | 0.537 | ||
DAXX | death-domain associated protein | 0.533 | ||
UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.532 | ||
TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.531 | ||
RNF7 | ring finger protein 7 | 0.528 | ||
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.525 | ||
NCOA3 | nuclear receptor coactivator 3 | 0.522 | ||
RNF2 | ring finger protein 2 | 0.516 | ||
CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.514 | ||
TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.513 | ||
MIB1 | mindbomb homolog 1 (Drosophila) | 0.512 | ||
SNX9 | sorting nexin 9 | 0.507 | ||
AURKB | aurora kinase B | 0.504 | ||
PSEN1 | presenilin 1 | 0.502 | Mouse | |
RNF38 | ring finger protein 38 | 0.502 | ||
PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.495 | ||
UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.494 | Human Yeast Fly | |
EXOSC9 | exosome component 9 | 0.492 | ||
RNF144B | ring finger protein 144B | 0.482 | ||
ECSIT | ECSIT homolog (Drosophila) | 0.477 | ||
NCF2 | neutrophil cytosolic factor 2 | 0.468 | ||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.465 | Yeast | |
MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.463 | ||
CDK1 | cyclin-dependent kinase 1 | 0.454 | ||
TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.452 | ||
MKRN1 | makorin ring finger protein 1 | 0.452 | ||
MYST2 | MYST histone acetyltransferase 2 | 0.447 | Human | |
CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.443 | ||
MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.436 | ||
HDAC6 | histone deacetylase 6 | 0.434 | Mouse | |
BAG2 | BCL2-associated athanogene 2 | 0.432 | ||
PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.430 | ||
CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.427 | ||
HSPA13 | heat shock protein 70kDa family, member 13 | 0.427 | ||
NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.426 | ||
ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.423 | ||
PTTG1 | pituitary tumor-transforming 1 | 0.423 | ||
USP9X | ubiquitin specific peptidase 9, X-linked | 0.422 | Fly | |
SEC24B | SEC24 family, member B (S. cerevisiae) | 0.415 | ||
SELS | selenoprotein S | 0.414 | ||
ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.414 | ||
BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.414 | Human | |
PML | promyelocytic leukemia | 0.411 | ||
ANAPC5 | anaphase promoting complex subunit 5 | 0.408 | ||
ERBB2IP | erbb2 interacting protein | 0.408 | ||
PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.403 | Human | |
FOXM1 | forkhead box M1 | 0.402 | ||
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.398 | ||
USP15 | ubiquitin specific peptidase 15 | 0.398 | Human | |
UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.395 | Human | |
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.394 | ||
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.392 | Mouse | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.391 | ||
ZNF263 | zinc finger protein 263 | 0.388 | ||
DERL1 | Der1-like domain family, member 1 | 0.387 | ||
CDT1 | chromatin licensing and DNA replication factor 1 | 0.384 | ||
TRIM5 | tripartite motif containing 5 | 0.379 | Human | |
PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.376 | ||
KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.374 | ||
UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.373 | Human | |
RNF10 | ring finger protein 10 | 0.370 | ||
HIPK3 | homeodomain interacting protein kinase 3 | 0.369 | ||
UBE2G1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | 0.367 | Human | |
RNF31 | ring finger protein 31 | 0.366 | ||
PIAS1 | protein inhibitor of activated STAT, 1 | 0.365 | Mouse | |
SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.365 | ||
UBASH3B | ubiquitin associated and SH3 domain containing B | 0.364 | ||
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.363 | ||
CDK6 | cyclin-dependent kinase 6 | 0.360 | ||
FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.355 | ||
SMAD1 | SMAD family member 1 | 0.354 | Human | |
NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.347 | Yeast | |
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.345 | ||
AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 | 0.340 | ||
TRIM23 | tripartite motif containing 23 | 0.339 | ||
BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.337 | Fly | |
EAPP | E2F-associated phosphoprotein | 0.337 | ||
UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.336 | Mouse | |
EXOSC1 | exosome component 1 | 0.332 | Yeast | |
UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.330 | Human Yeast | |
TRIM27 | tripartite motif containing 27 | 0.329 | Human | |
ANXA7 | annexin A7 | 0.325 | ||
VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.325 | ||
USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.324 | Human | |
CSNK1D | casein kinase 1, delta | 0.322 | Mouse Fly | |
MYST1 | MYST histone acetyltransferase 1 | 0.322 | Human | |
DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.322 | Yeast | |
PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.322 | Human | |
PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.319 | ||
BIRC3 | baculoviral IAP repeat containing 3 | 0.319 | Human | |
FBXW5 | F-box and WD repeat domain containing 5 | 0.318 | ||
EPOR | erythropoietin receptor | 0.316 | ||
CCNB2 | cyclin B2 | 0.312 | ||
DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.311 | ||
COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.310 | ||
GFM1 | G elongation factor, mitochondrial 1 | 0.309 | ||
DCAF7 | DDB1 and CUL4 associated factor 7 | 0.309 | ||
MED21 | mediator complex subunit 21 | 0.307 | ||
IGF1R | insulin-like growth factor 1 receptor | 0.307 | ||
TRIM32 | tripartite motif containing 32 | 0.306 | ||
ATXN1 | ataxin 1 | 0.306 | ||
MED15 | mediator complex subunit 15 | 0.306 | ||
CHMP4B | chromatin modifying protein 4B | 0.304 | ||
PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.302 | Yeast | |
CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.300 | ||
HSPA1B | heat shock 70kDa protein 1B | 0.299 | ||
FLNB | filamin B, beta | 0.299 | ||
STRN3 | striatin, calmodulin binding protein 3 | 0.298 | ||
UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.296 | Mouse | |
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.294 | Human | |
SSR1 | signal sequence receptor, alpha | 0.290 | ||
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.287 | ||
INO80 | INO80 homolog (S. cerevisiae) | 0.286 | ||
RNF168 | ring finger protein 168 | 0.285 | ||
ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.284 | ||
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.284 | ||
EXOSC10 | exosome component 10 | 0.280 | ||
HIPK2 | homeodomain interacting protein kinase 2 | 0.276 | ||
FBXO33 | F-box protein 33 | 0.275 | ||
AR | androgen receptor | 0.275 | ||
ZNF496 | zinc finger protein 496 | 0.275 | ||
PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.274 | ||
RAD23A | RAD23 homolog A (S. cerevisiae) | 0.272 | ||
TBK1 | TANK-binding kinase 1 | 0.266 | ||
FBXO3 | F-box protein 3 | 0.264 | ||
KCTD10 | potassium channel tetramerisation domain containing 10 | 0.262 | Human | |
UBE2K | ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) | 0.261 | Yeast Mouse | |
DTX3L | deltex 3-like (Drosophila) | 0.261 | ||
QKI | quaking homolog, KH domain RNA binding (mouse) | 0.260 | ||
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.257 | ||
FBXL15 | F-box and leucine-rich repeat protein 15 | 0.257 | ||
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.255 | ||
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.252 | ||
NBN | nibrin | 0.251 | ||
STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.247 | ||
RNF185 | ring finger protein 185 | 0.247 | Human | |
DIS3 | DIS3 mitotic control homolog (S. cerevisiae) | 0.247 | ||
SEC63 | SEC63 homolog (S. cerevisiae) | 0.246 | ||
GCLM | glutamate-cysteine ligase, modifier subunit | 0.246 | ||
UBXN6 | UBX domain protein 6 | 0.244 | ||
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.243 | ||
CYLD | cylindromatosis (turban tumor syndrome) | 0.242 | ||
TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.240 | ||
UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.237 | ||
UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.231 | ||
PCM1 | pericentriolar material 1 | 0.229 | ||
USP38 | ubiquitin specific peptidase 38 | 0.227 | ||
SLX1B | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | 0.227 | ||
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.227 | ||
MBD3 | methyl-CpG binding domain protein 3 | 0.226 | ||
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.226 | ||
ANKRD13A | ankyrin repeat domain 13A | 0.224 | ||
PIAS4 | protein inhibitor of activated STAT, 4 | 0.223 | ||
MTA2 | metastasis associated 1 family, member 2 | 0.223 | Human | |
CUL4B | cullin 4B | 0.221 | ||
NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.220 | ||
VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.219 | ||
CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.219 | ||
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.217 | Human | |
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.217 | ||
UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.216 | Mouse | |
RANBP9 | RAN binding protein 9 | 0.216 | ||
CCDC101 | coiled-coil domain containing 101 | 0.215 | ||
GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.212 | ||
CDYL | chromodomain protein, Y-like | 0.209 | ||
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.209 | ||
VPRBP | Vpr (HIV-1) binding protein | 0.208 | ||
CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.207 | ||
RANBP2 | RAN binding protein 2 | 0.206 | ||
SIRT2 | sirtuin 2 | 0.206 | ||
PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.204 | ||
NSFL1C | NSFL1 (p97) cofactor (p47) | 0.202 | Yeast | |
SNIP1 | Smad nuclear interacting protein 1 | 0.202 | ||
NCAM1 | neural cell adhesion molecule 1 | 0.201 | ||
RNF8 | ring finger protein 8 | 0.201 | ||
CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.199 | ||
INCENP | inner centromere protein antigens 135/155kDa | 0.198 | ||
SIRT1 | sirtuin 1 | 0.198 | ||
PAIP2 | poly(A) binding protein interacting protein 2 | 0.198 | ||
CHFR | checkpoint with forkhead and ring finger domains | 0.196 | ||
WDR26 | WD repeat domain 26 | 0.195 | ||
SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.195 | ||
DLG1 | discs, large homolog 1 (Drosophila) | 0.195 | ||
RNF4 | ring finger protein 4 | 0.194 | ||
PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.193 | Mouse | |
CLOCK | clock homolog (mouse) | 0.191 | Mouse | |
TP53BP1 | tumor protein p53 binding protein 1 | 0.191 | ||
CAND1 | cullin-associated and neddylation-dissociated 1 | 0.191 | ||
APC | adenomatous polyposis coli | 0.190 | ||
VHL | von Hippel-Lindau tumor suppressor | 0.190 | ||
RNF126 | ring finger protein 126 | 0.189 | ||
PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.189 | ||
MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.189 | ||
PCBP2 | poly(rC) binding protein 2 | 0.186 | ||
UBE3A | ubiquitin protein ligase E3A | 0.181 | Mouse Fly | |
AXIN2 | axin 2 | 0.181 | ||
PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.180 | ||
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.179 | Yeast | |
NCK2 | NCK adaptor protein 2 | 0.179 | ||
UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.178 | ||
BMI1 | BMI1 polycomb ring finger oncogene | 0.178 | ||
TPBG | trophoblast glycoprotein | 0.178 | ||
TRAF4 | TNF receptor-associated factor 4 | 0.178 | ||
UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.178 | Mouse | |
MYO1C | myosin IC | 0.177 | ||
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.177 | ||
RC3H2 | ring finger and CCCH-type domains 2 | 0.176 | ||
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.176 | ||
USP2 | ubiquitin specific peptidase 2 | 0.175 | Yeast | |
RBL1 | retinoblastoma-like 1 (p107) | 0.174 | Human | |
CCND1 | cyclin D1 | 0.173 | ||
ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.173 | Mouse | |
LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.171 | ||
RNF114 | ring finger protein 114 | 0.170 | ||
TRIM25 | tripartite motif containing 25 | 0.167 | ||
PDIA6 | protein disulfide isomerase family A, member 6 | 0.166 | ||
PPME1 | protein phosphatase methylesterase 1 | 0.166 | ||
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.166 | ||
C11orf58 | chromosome 11 open reading frame 58 | 0.166 | ||
LRRK2 | leucine-rich repeat kinase 2 | 0.166 | Mouse | |
ORC1 | origin recognition complex, subunit 1 | 0.166 | ||
LPXN | leupaxin | 0.166 | Human | |
BABAM1 | BRISC and BRCA1 A complex member 1 | 0.165 | ||
FEM1B | fem-1 homolog b (C. elegans) | 0.163 | ||
UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | 0.162 | ||
COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.161 | ||
EXOSC4 | exosome component 4 | 0.160 | Yeast | |
TFDP1 | transcription factor Dp-1 | 0.160 | ||
SNAI1 | snail homolog 1 (Drosophila) | 0.157 | ||
KDM1A | lysine (K)-specific demethylase 1A | 0.156 | ||
DCTN4 | dynactin 4 (p62) | 0.156 | ||
CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.155 | ||
CDKN2AIP | CDKN2A interacting protein | 0.155 | ||
TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.155 | ||
TLK1 | tousled-like kinase 1 | 0.154 | Human | |
AIMP1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | 0.154 | ||
FBXL5 | F-box and leucine-rich repeat protein 5 | 0.154 | ||
GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.154 | ||
NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.153 | ||
PRC1 | protein regulator of cytokinesis 1 | 0.153 | ||
ATF3 | activating transcription factor 3 | 0.153 | ||
NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.153 | ||
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.153 | Human | |
DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.152 | ||
SFN | stratifin | 0.152 | ||
EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.151 | ||
ATM | ataxia telangiectasia mutated | 0.151 | ||
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.150 | ||
ING2 | inhibitor of growth family, member 2 | 0.149 | ||
MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.149 | Rat | |
HERC2 | hect domain and RLD 2 | 0.149 | ||
RPN1 | ribophorin I | 0.149 | ||
UBXN2A | UBX domain protein 2A | 0.149 | ||
XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.148 | ||
TMEM173 | transmembrane protein 173 | 0.148 | ||
WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.147 | Human Yeast Mouse | |
CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.147 | ||
TRIM37 | tripartite motif containing 37 | 0.147 | ||
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.146 | Human | |
MLL2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.145 | ||
ATF5 | activating transcription factor 5 | 0.145 | ||
CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.145 | ||
C11orf2 | chromosome 11 open reading frame 2 | 0.144 | ||
ZFAND5 | zinc finger, AN1-type domain 5 | 0.143 | ||
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.143 | ||
TSG101 | tumor susceptibility gene 101 | 0.143 | ||
RNF181 | ring finger protein 181 | 0.142 | ||
PRKCD | protein kinase C, delta | 0.142 | ||
ZYG11B | zyg-11 homolog B (C. elegans) | 0.142 | ||
KIAA0232 | KIAA0232 | 0.142 | ||
PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 0.141 | ||
NOMO1 | NODAL modulator 1 | 0.140 | ||
KPNB1 | karyopherin (importin) beta 1 | 0.140 | ||
IER3 | immediate early response 3 | 0.139 | ||
HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.139 | ||
TGS1 | trimethylguanosine synthase 1 | 0.139 | ||
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.139 | ||
BTBD10 | BTB (POZ) domain containing 10 | 0.138 | ||
TBP | TATA box binding protein | 0.137 | ||
SGOL2 | shugoshin-like 2 (S. pombe) | 0.135 | ||
NCOR1 | nuclear receptor corepressor 1 | 0.135 | ||
RBBP7 | retinoblastoma binding protein 7 | 0.134 | ||
ADAM15 | ADAM metallopeptidase domain 15 | 0.133 | ||
NUDCD3 | NudC domain containing 3 | 0.133 | ||
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.133 | ||
STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.133 | ||
FAF1 | Fas (TNFRSF6) associated factor 1 | 0.133 | ||
BFAR | bifunctional apoptosis regulator | 0.133 | ||
MAVS | mitochondrial antiviral signaling protein | 0.132 | ||
ILK | integrin-linked kinase | 0.131 | ||
SKA1 | spindle and kinetochore associated complex subunit 1 | 0.131 | ||
NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.131 | ||
GATAD2B | GATA zinc finger domain containing 2B | 0.130 | ||
PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.130 | ||
PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.130 | ||
TRIM33 | tripartite motif containing 33 | 0.130 | ||
TRIM41 | tripartite motif containing 41 | 0.129 | Human | |
UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.129 | Mouse | |
COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.128 | ||
DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.128 | ||
BAG1 | BCL2-associated athanogene | 0.128 | ||
CDC37L1 | cell division cycle 37 homolog (S. cerevisiae)-like 1 | 0.127 | ||
RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.127 | ||
RNF130 | ring finger protein 130 | 0.127 | ||
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.127 | ||
FBXO28 | F-box protein 28 | 0.126 | ||
ZNF207 | zinc finger protein 207 | 0.126 | ||
KARS | lysyl-tRNA synthetase | 0.125 | ||
SAE1 | SUMO1 activating enzyme subunit 1 | 0.125 | ||
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.124 | Yeast | |
SKIL | SKI-like oncogene | 0.124 | ||
STIP1 | stress-induced-phosphoprotein 1 | 0.123 | ||
NEURL4 | neuralized homolog 4 (Drosophila) | 0.123 | ||
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.123 | ||
PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.123 | ||
MTA1 | metastasis associated 1 | 0.122 | ||
HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.122 | ||
UBD | ubiquitin D | 0.122 | ||
ANKRD13C | ankyrin repeat domain 13C | 0.122 | ||
NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.121 | ||
GFI1B | growth factor independent 1B transcription repressor | 0.120 | ||
ARNT | aryl hydrocarbon receptor nuclear translocator | 0.119 | ||
ASF1A | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) | 0.119 | ||
ANAPC10 | anaphase promoting complex subunit 10 | 0.118 | Yeast | |
ZMYM2 | zinc finger, MYM-type 2 | 0.118 | ||
CCDC99 | coiled-coil domain containing 99 | 0.117 | ||
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.117 | Human | |
UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.117 | ||
UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.117 | ||
TRAF2 | TNF receptor-associated factor 2 | 0.117 | ||
CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.117 | ||
RIOK2 | RIO kinase 2 (yeast) | 0.117 | ||
RHOB | ras homolog gene family, member B | 0.117 | ||
PRKCB | protein kinase C, beta | 0.116 | ||
KEAP1 | kelch-like ECH-associated protein 1 | 0.116 | Human | |
VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | 0.116 | ||
RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.116 | ||
ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.116 | ||
LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.116 | Human | |
RFWD3 | ring finger and WD repeat domain 3 | 0.115 | ||
MTMR6 | myotubularin related protein 6 | 0.115 | ||
MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.115 | ||
PAPOLA | poly(A) polymerase alpha | 0.115 | ||
BTBD2 | BTB (POZ) domain containing 2 | 0.113 | ||
RANGAP1 | Ran GTPase activating protein 1 | 0.113 | ||
SIAH2 | seven in absentia homolog 2 (Drosophila) | 0.113 | Human | |
TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.112 | ||
TOR1AIP2 | torsin A interacting protein 2 | 0.112 | ||
SEC31A | SEC31 homolog A (S. cerevisiae) | 0.112 | ||
UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.112 | ||
DERL2 | Der1-like domain family, member 2 | 0.112 | ||
GORAB | golgin, RAB6-interacting | 0.111 | ||
SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.111 | ||
HSPA1A | heat shock 70kDa protein 1A | 0.111 | ||
ATMIN | ATM interactor | 0.111 | ||
LAP3 | leucine aminopeptidase 3 | 0.111 | ||
KSR1 | kinase suppressor of ras 1 | 0.110 | Human | |
RBBP5 | retinoblastoma binding protein 5 | 0.109 | ||
MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.109 | ||
DAPK1 | death-associated protein kinase 1 | 0.109 | ||
PHF20 | PHD finger protein 20 | 0.109 | ||
MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.109 | ||
RNF103 | ring finger protein 103 | 0.108 | ||
GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.108 | ||
TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.108 | ||
KIF5B | kinesin family member 5B | 0.108 | ||
AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.107 | ||
UBE2S | ubiquitin-conjugating enzyme E2S | 0.107 | ||
CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon | 0.106 | ||
PHF21A | PHD finger protein 21A | 0.106 | ||
BTBD1 | BTB (POZ) domain containing 1 | 0.106 | ||
RAD18 | RAD18 homolog (S. cerevisiae) | 0.106 | ||
OTUD5 | OTU domain containing 5 | 0.105 | ||
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.105 | ||
LIN28B | lin-28 homolog B (C. elegans) | 0.105 | ||
CSDE1 | cold shock domain containing E1, RNA-binding | 0.105 | ||
MAPK9 | mitogen-activated protein kinase 9 | 0.105 | ||
COIL | coilin | 0.105 | ||
LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.104 | ||
STMN1 | stathmin 1 | 0.104 | ||
CCND3 | cyclin D3 | 0.103 | ||
PIAS2 | protein inhibitor of activated STAT, 2 | 0.102 | ||
VTA1 | Vps20-associated 1 homolog (S. cerevisiae) | 0.102 | ||
SLC38A2 | solute carrier family 38, member 2 | 0.102 | ||
HDAC11 | histone deacetylase 11 | 0.102 | ||
MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.102 | ||
COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.102 | Fly | |
E2F1 | E2F transcription factor 1 | 0.101 | ||
UBB | ubiquitin B | 0.101 | ||
ATF7IP | activating transcription factor 7 interacting protein | 0.100 | ||
UBQLN4 | ubiquilin 4 | 0.100 | ||
CDK17 | cyclin-dependent kinase 17 | 0.100 | ||
DEPDC1 | DEP domain containing 1 | 0.099 | ||
CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.098 | ||
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.098 | ||
RBBP8 | retinoblastoma binding protein 8 | 0.097 | ||
USO1 | USO1 vesicle docking protein homolog (yeast) | 0.097 | ||
JUN | jun proto-oncogene | 0.097 | ||
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.096 | ||
FBXW9 | F-box and WD repeat domain containing 9 | 0.096 | ||
KLHL2 | kelch-like 2, Mayven (Drosophila) | 0.096 | Human | |
TRIM34 | tripartite motif containing 34 | 0.096 | ||
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.096 | ||
DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.095 | ||
PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.095 | ||
NPEPPS | aminopeptidase puromycin sensitive | 0.095 | ||
THOC3 | THO complex 3 | 0.095 | ||
USP25 | ubiquitin specific peptidase 25 | 0.095 | ||
ARRB2 | arrestin, beta 2 | 0.095 | ||
IFI16 | interferon, gamma-inducible protein 16 | 0.095 | ||
UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.094 | ||
PAWR | PRKC, apoptosis, WT1, regulator | 0.094 | ||
TRIM63 | tripartite motif containing 63 | 0.094 | Human Mouse | |
VCL | vinculin | 0.094 | ||
CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.093 | ||
ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.093 | ||
AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.093 | ||
EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.093 | ||
PXN | paxillin | 0.093 | Human | |
CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.093 | ||
HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.093 | ||
CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.093 | Fly | |
BCL2L1 | BCL2-like 1 | 0.093 | ||
GLI1 | GLI family zinc finger 1 | 0.092 | ||
SLU7 | SLU7 splicing factor homolog (S. cerevisiae) | 0.091 | ||
SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 | 0.091 | ||
MID1 | midline 1 (Opitz/BBB syndrome) | 0.090 | ||
CBX5 | chromobox homolog 5 | 0.090 | ||
WDR13 | WD repeat domain 13 | 0.090 | ||
RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.090 | ||
UNC45A | unc-45 homolog A (C. elegans) | 0.090 | ||
PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.090 | ||
PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.089 | ||
ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.089 | ||
DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 0.089 | ||
RING1 | ring finger protein 1 | 0.089 | ||
RAB21 | RAB21, member RAS oncogene family | 0.089 | ||
USPL1 | ubiquitin specific peptidase like 1 | 0.089 | ||
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.089 | ||
TROVE2 | TROVE domain family, member 2 | 0.088 | ||
IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.088 | ||
CTR9 | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.088 | ||
SOCS5 | suppressor of cytokine signaling 5 | 0.087 | ||
TOM1L1 | target of myb1 (chicken)-like 1 | 0.087 | ||
HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.087 | ||
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.087 | ||
MAK | male germ cell-associated kinase | 0.087 | ||
OSTC | oligosaccharyltransferase complex subunit | 0.087 | ||
NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.086 | ||
MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.086 | ||
CARD11 | caspase recruitment domain family, member 11 | 0.085 | ||
FBXO30 | F-box protein 30 | 0.085 | ||
BIRC8 | baculoviral IAP repeat containing 8 | 0.085 | Human | |
ARMC7 | armadillo repeat containing 7 | 0.085 | ||
EEF1G | eukaryotic translation elongation factor 1 gamma | 0.085 | ||
RLIM | ring finger protein, LIM domain interacting | 0.085 | Mouse | |
AUP1 | ancient ubiquitous protein 1 | 0.085 | ||
SETX | senataxin | 0.085 | ||
TRIM9 | tripartite motif containing 9 | 0.085 | ||
TXNL1 | thioredoxin-like 1 | 0.084 | ||
BBS10 | Bardet-Biedl syndrome 10 | 0.084 | ||
KDM4A | lysine (K)-specific demethylase 4A | 0.084 | ||
SRP54 | signal recognition particle 54kDa | 0.084 | ||
TUBB2C | tubulin, beta 2C | 0.083 | ||
MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.083 | ||
FBXO4 | F-box protein 4 | 0.083 | ||
CCDC50 | coiled-coil domain containing 50 | 0.083 | ||
PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.083 | ||
PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.083 | ||
POLH | polymerase (DNA directed), eta | 0.083 | ||
UBE2C | ubiquitin-conjugating enzyme E2C | 0.083 | ||
HIST2H2AC | histone cluster 2, H2ac | 0.083 | ||
TRAF1 | TNF receptor-associated factor 1 | 0.083 | ||
DBP | D site of albumin promoter (albumin D-box) binding protein | 0.083 | ||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.083 | ||
UBOX5 | U-box domain containing 5 | 0.082 | ||
MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.082 | ||
PNPLA8 | patatin-like phospholipase domain containing 8 | 0.082 | ||
RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.082 | ||
CD44 | CD44 molecule (Indian blood group) | 0.082 | ||
SH3GL2 | SH3-domain GRB2-like 2 | 0.082 | ||
FAM175B | family with sequence similarity 175, member B | 0.082 | ||
FYN | FYN oncogene related to SRC, FGR, YES | 0.081 | ||
ANKRD28 | ankyrin repeat domain 28 | 0.081 | ||
XBP1 | X-box binding protein 1 | 0.081 | ||
CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.081 | ||
KALRN | kalirin, RhoGEF kinase | 0.081 | ||
MEX3B | mex-3 homolog B (C. elegans) | 0.081 | ||
C19orf39 | chromosome 19 open reading frame 39 | 0.081 | ||
SNX18 | sorting nexin 18 | 0.081 | ||
SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.081 | ||
SP100 | SP100 nuclear antigen | 0.080 | ||
VBP1 | von Hippel-Lindau binding protein 1 | 0.080 | ||
IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.080 | ||
TRIB3 | tribbles homolog 3 (Drosophila) | 0.080 | Fly | |
TRIP12 | thyroid hormone receptor interactor 12 | 0.080 | ||
MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.080 | ||
KIF2C | kinesin family member 2C | 0.080 | ||
TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.080 | ||
PHF20L1 | PHD finger protein 20-like 1 | 0.079 | ||
EIF4E | eukaryotic translation initiation factor 4E | 0.079 | ||
KPNA6 | karyopherin alpha 6 (importin alpha 7) | 0.079 | ||
RBM4 | RNA binding motif protein 4 | 0.079 | ||
RNF40 | ring finger protein 40 | 0.079 | Human Rat | |
MTDH | metadherin | 0.078 | ||
NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.078 | ||
RIF1 | RAP1 interacting factor homolog (yeast) | 0.078 | ||
SLC25A36 | solute carrier family 25, member 36 | 0.077 | ||
CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.077 | ||
KLHL13 | kelch-like 13 (Drosophila) | 0.077 | Human | |
RCHY1 | ring finger and CHY zinc finger domain containing 1 | 0.077 | ||
MYD88 | myeloid differentiation primary response gene (88) | 0.077 | ||
RNF26 | ring finger protein 26 | 0.077 | ||
SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.077 | ||
FUNDC2 | FUN14 domain containing 2 | 0.076 | ||
TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.076 | ||
SOCS2 | suppressor of cytokine signaling 2 | 0.076 | Human | |
FEN1 | flap structure-specific endonuclease 1 | 0.075 | ||
DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.075 | ||
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.075 | ||
MRPL10 | mitochondrial ribosomal protein L10 | 0.075 | ||
PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.075 | ||
RCOR1 | REST corepressor 1 | 0.075 | ||
C12orf44 | chromosome 12 open reading frame 44 | 0.075 | ||
MKI67 | antigen identified by monoclonal antibody Ki-67 | 0.075 | ||
MYO6 | myosin VI | 0.074 | ||
LNX1 | ligand of numb-protein X 1 | 0.074 | Mouse | |
UBA7 | ubiquitin-like modifier activating enzyme 7 | 0.074 | ||
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.074 | ||
KLF5 | Kruppel-like factor 5 (intestinal) | 0.074 | ||
SQSTM1 | sequestosome 1 | 0.074 | ||
RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.074 | ||
DTX3 | deltex homolog 3 (Drosophila) | 0.073 | ||
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.073 | ||
STAU1 | staufen, RNA binding protein, homolog 1 (Drosophila) | 0.073 | ||
SNX16 | sorting nexin 16 | 0.073 | ||
CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.073 | ||
TRIP13 | thyroid hormone receptor interactor 13 | 0.073 | ||
SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.073 | ||
TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 0.073 | ||
KIAA1524 | KIAA1524 | 0.073 | ||
GRSF1 | G-rich RNA sequence binding factor 1 | 0.073 | ||
SHPRH | SNF2 histone linker PHD RING helicase | 0.073 | ||
DHPS | deoxyhypusine synthase | 0.072 | ||
WDR45 | WD repeat domain 45 | 0.072 | ||
MAPK6 | mitogen-activated protein kinase 6 | 0.072 | ||
COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.072 | Worm | |
SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | 0.072 | ||
TCP1 | t-complex 1 | 0.072 | ||
RAB18 | RAB18, member RAS oncogene family | 0.072 | ||
MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.072 | ||
MBD1 | methyl-CpG binding domain protein 1 | 0.071 | ||
POLD1 | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 0.071 | ||
SORBS3 | sorbin and SH3 domain containing 3 | 0.071 | ||
TGFBR1 | transforming growth factor, beta receptor 1 | 0.071 | ||
NCSTN | nicastrin | 0.071 | ||
MPHOSPH6 | M-phase phosphoprotein 6 | 0.071 | ||
S100A4 | S100 calcium binding protein A4 | 0.070 | ||
PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.070 | ||
IRF9 | interferon regulatory factor 9 | 0.070 | ||
PINK1 | PTEN induced putative kinase 1 | 0.070 | Fly | |
WAC | WW domain containing adaptor with coiled-coil | 0.070 | ||
FKBP3 | FK506 binding protein 3, 25kDa | 0.070 | ||
HSF1 | heat shock transcription factor 1 | 0.070 | ||
POLR2C | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 0.070 | ||
KCTD3 | potassium channel tetramerisation domain containing 3 | 0.070 | ||
OTUD4 | OTU domain containing 4 | 0.069 | ||
RIC8A | resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | 0.069 | ||
DPP8 | dipeptidyl-peptidase 8 | 0.069 | ||
SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.069 | ||
SOD1 | superoxide dismutase 1, soluble | 0.069 | ||
MATK | megakaryocyte-associated tyrosine kinase | 0.069 | Human |