Process View
The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation of peptide antigen"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
HLA-A | major histocompatibility complex, class I, A | 1.000 | ||
HLA-DRA | major histocompatibility complex, class II, DR alpha | 1.000 | ||
HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 | 1.000 | ||
TAPBP | TAP binding protein (tapasin) | 0.999 | ||
HLA-F | major histocompatibility complex, class I, F | 0.999 | Human | |
HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.998 | ||
HLA-B | major histocompatibility complex, class I, B | 0.994 | ||
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | 0.994 | Human Mouse | |
HLA-C | major histocompatibility complex, class I, C | 0.963 | ||
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.959 | Mouse | |
HLA-DMB | major histocompatibility complex, class II, DM beta | 0.958 | ||
B2M | beta-2-microglobulin | 0.932 | Mouse | |
HLA-G | major histocompatibility complex, class I, G | 0.925 | Human | |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.915 | ||
HLA-DRB5 | major histocompatibility complex, class II, DR beta 5 | 0.801 | Human | |
HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | 0.674 | ||
HLA-E | major histocompatibility complex, class I, E | 0.489 | ||
SYK | spleen tyrosine kinase | 0.414 | ||
TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.307 | ||
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.287 | ||
GRN | granulin | 0.254 | ||
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.222 | Human | |
PDIA3 | protein disulfide isomerase family A, member 3 | 0.159 | ||
NPC2 | Niemann-Pick disease, type C2 | 0.154 | ||
HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.137 | ||
PSAP | prosaposin | 0.103 | ||
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.095 | ||
CTSA | cathepsin A | 0.072 | ||
PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.044 | ||
NLRC4 | NLR family, CARD domain containing 4 | 0.040 | ||
CST3 | cystatin C | 0.036 | ||
TPP1 | tripeptidyl peptidase I | 0.034 | ||
TAPBPL | TAP binding protein-like | 0.034 | ||
P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.028 | ||
BLNK | B-cell linker | 0.027 | ||
MEFV | Mediterranean fever | 0.026 | ||
MAN2B1 | mannosidase, alpha, class 2B, member 1 | 0.023 | ||
GM2A | GM2 ganglioside activator | 0.022 | ||
CTSS | cathepsin S | 0.022 | ||
LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.020 | ||
UBASH3B | ubiquitin associated and SH3 domain containing B | 0.019 | ||
BAG3 | BCL2-associated athanogene 3 | 0.018 | ||
TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.018 | ||
HLA-DQA2 | major histocompatibility complex, class II, DQ alpha 2 | 0.017 | ||
PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.017 | ||
MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.016 | ||
ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.016 | ||
C1orf38 | chromosome 1 open reading frame 38 | 0.016 | ||
OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.015 | ||
LY86 | lymphocyte antigen 86 | 0.015 | ||
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.015 | ||
CTSH | cathepsin H | 0.015 | ||
TYROBP | TYRO protein tyrosine kinase binding protein | 0.014 | ||
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.014 | ||
HCP5 | HLA complex P5 | 0.014 | ||
CAPG | capping protein (actin filament), gelsolin-like | 0.013 | ||
PELI3 | pellino homolog 3 (Drosophila) | 0.013 | ||
INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.012 | ||
IFI30 | interferon, gamma-inducible protein 30 | 0.011 | Mouse | |
CTSB | cathepsin B | 0.011 |