IMP

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of lymphocyte mediated immunity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of lymphocyte mediated immunity" (in gray)

Name	Description	Probability	Func Analog Organism
B2M	beta-2-microglobulin	0.988	Mouse
HLA-A	major histocompatibility complex, class I, A	0.979
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.960
HLA-C	major histocompatibility complex, class I, C	0.919	Human
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.846
SLAMF1	signaling lymphocytic activation molecule family member 1	0.841
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.829	Human
SH2D1A	SH2 domain containing 1A	0.800	Mouse
TAPBP	TAP binding protein (tapasin)	0.751
IL4R	interleukin 4 receptor	0.727
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.704
HLA-B	major histocompatibility complex, class I, B	0.685
CCL5	chemokine (C-C motif) ligand 5	0.681	Human
TRAF3	TNF receptor-associated factor 3	0.678	Human
CD84	CD84 molecule	0.639
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.585
CD40	CD40 molecule, TNF receptor superfamily member 5	0.521	Mouse Rat
CCR5	chemokine (C-C motif) receptor 5	0.521
HLA-G	major histocompatibility complex, class I, G	0.517	Human
IL2RB	interleukin 2 receptor, beta	0.491
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.337
CCL4	chemokine (C-C motif) ligand 4	0.270	Human
GRAP2	GRB2-related adaptor protein 2	0.268
CXCL9	chemokine (C-X-C motif) ligand 9	0.246
TRAF1	TNF receptor-associated factor 1	0.239	Human
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.205
FASLG	Fas ligand (TNF superfamily, member 6)	0.204
ITM2B	integral membrane protein 2B	0.199
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	0.197
TRAF2	TNF receptor-associated factor 2	0.190
BIRC3	baculoviral IAP repeat containing 3	0.181
IFNG	interferon, gamma	0.164
IL23A	interleukin 23, alpha subunit p19	0.156	Mouse
INSR	insulin receptor	0.148
SYK	spleen tyrosine kinase	0.146
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.130
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.128
HLA-E	major histocompatibility complex, class I, E	0.123
GBA	glucosidase, beta, acid	0.121
CXCL10	chemokine (C-X-C motif) ligand 10	0.121
GZMK	granzyme K (granzyme 3; tryptase II)	0.117
CD80	CD80 molecule	0.115
ICAM1	intercellular adhesion molecule 1	0.114
IL2RG	interleukin 2 receptor, gamma	0.084
SQSTM1	sequestosome 1	0.078
ENG	endoglin	0.076
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.074
KLRC3	killer cell lectin-like receptor subfamily C, member 3	0.074	Human
CCL2	chemokine (C-C motif) ligand 2	0.070	Human
CD22	CD22 molecule	0.069
CXCL3	chemokine (C-X-C motif) ligand 3	0.067
CFH	complement factor H	0.063
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.061
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.059
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.059
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.058
PRF1	perforin 1 (pore forming protein)	0.055
CXCL11	chemokine (C-X-C motif) ligand 11	0.055
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.054
TP53BP1	tumor protein p53 binding protein 1	0.054
RIPK2	receptor-interacting serine-threonine kinase 2	0.054
PVRL4	poliovirus receptor-related 4	0.053
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.053
TRADD	TNFRSF1A-associated via death domain	0.053
CCR7	chemokine (C-C motif) receptor 7	0.053
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.053
CCL8	chemokine (C-C motif) ligand 8	0.051	Human
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.051
CCR1	chemokine (C-C motif) receptor 1	0.051
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.050
CXCR6	chemokine (C-X-C motif) receptor 6	0.050
HLA-F	major histocompatibility complex, class I, F	0.050	Human
IRF1	interferon regulatory factor 1	0.050
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.050	Human
NUMBL	numb homolog (Drosophila)-like	0.048
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.048
CD8A	CD8a molecule	0.048
FAS	Fas (TNF receptor superfamily, member 6)	0.048
TRAF5	TNF receptor-associated factor 5	0.047	Human
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.044
CCL7	chemokine (C-C motif) ligand 7	0.044	Human
NCSTN	nicastrin	0.044
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.043
GNS	glucosamine (N-acetyl)-6-sulfatase	0.043
CCR4	chemokine (C-C motif) receptor 4	0.040
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.038
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.037
CCL19	chemokine (C-C motif) ligand 19	0.036	Human
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.035	Mouse
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.035
CCL22	chemokine (C-C motif) ligand 22	0.035	Human
IL10RA	interleukin 10 receptor, alpha	0.034
IL18RAP	interleukin 18 receptor accessory protein	0.034
KLRC2	killer cell lectin-like receptor subfamily C, member 2	0.034	Human
GNLY	granulysin	0.033
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.033
CD86	CD86 molecule	0.032
NKG7	natural killer cell group 7 sequence	0.032
TNF	tumor necrosis factor	0.032
JAK2	Janus kinase 2	0.032
IL10	interleukin 10	0.031
GPR171	G protein-coupled receptor 171	0.031
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.031
CCL13	chemokine (C-C motif) ligand 13	0.031	Human
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.031
IL6	interleukin 6 (interferon, beta 2)	0.031
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.031
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.030
DPP4	dipeptidyl-peptidase 4	0.029
EPOR	erythropoietin receptor	0.029
RAB14	RAB14, member RAS oncogene family	0.029
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.029
TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.029	Mouse Rat
JAK1	Janus kinase 1	0.029
IRF4	interferon regulatory factor 4	0.028
TRAF6	TNF receptor-associated factor 6	0.028
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.027
CD160	CD160 molecule	0.027
CD2	CD2 molecule	0.027
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.026
CXCL13	chemokine (C-X-C motif) ligand 13	0.026
GPR65	G protein-coupled receptor 65	0.026
TLR2	toll-like receptor 2	0.026
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.025
STAT4	signal transducer and activator of transcription 4	0.024
IL7R	interleukin 7 receptor	0.024
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.023
TNFRSF17	tumor necrosis factor receptor superfamily, member 17	0.022
IGSF6	immunoglobulin superfamily, member 6	0.022
IL8	interleukin 8	0.022
ICOS	inducible T-cell co-stimulator	0.022
FPR3	formyl peptide receptor 3	0.021
ITK	IL2-inducible T-cell kinase	0.021
NSF	N-ethylmaleimide-sensitive factor	0.021
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.021	Mouse
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.020
STAP2	signal transducing adaptor family member 2	0.020
BCL10	B-cell CLL/lymphoma 10	0.020
KLRF1	killer cell lectin-like receptor subfamily F, member 1	0.020
VCAM1	vascular cell adhesion molecule 1	0.020
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.020
CD96	CD96 molecule	0.019
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.019
FTL	ferritin, light polypeptide	0.019
XCL2	chemokine (C motif) ligand 2	0.019	Human
CCL11	chemokine (C-C motif) ligand 11	0.019	Human
UBASH3B	ubiquitin associated and SH3 domain containing B	0.019
KLRG1	killer cell lectin-like receptor subfamily G, member 1	0.019	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.019
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.019
STX6	syntaxin 6	0.019
CD48	CD48 molecule	0.019
UBD	ubiquitin D	0.018
CARD11	caspase recruitment domain family, member 11	0.018
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.018
CSF1	colony stimulating factor 1 (macrophage)	0.018
IRS1	insulin receptor substrate 1	0.018
SH2D1B	SH2 domain containing 1B	0.017	Mouse
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.017	Human
ZMYND11	zinc finger, MYND-type containing 11	0.017
TRD@	T cell receptor delta locus	0.017
TXK	TXK tyrosine kinase	0.017
CD163	CD163 molecule	0.016
CD40LG	CD40 ligand	0.016
OASL	2'-5'-oligoadenylate synthetase-like	0.016
CD83	CD83 molecule	0.016
CCR2	chemokine (C-C motif) receptor 2	0.015
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.015
IDO1	indoleamine 2,3-dioxygenase 1	0.015
CLTC	clathrin, heavy chain (Hc)	0.015
CCR3	chemokine (C-C motif) receptor 3	0.015
RGS1	regulator of G-protein signaling 1	0.015
MDC1	mediator of DNA-damage checkpoint 1	0.014
XCL1	chemokine (C motif) ligand 1	0.014
SELE	selectin E	0.014
IL2RA	interleukin 2 receptor, alpha	0.014
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.014
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.014
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	0.014
CXCL2	chemokine (C-X-C motif) ligand 2	0.014
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.014
TRAT1	T cell receptor associated transmembrane adaptor 1	0.014
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.014
APLP2	amyloid beta (A4) precursor-like protein 2	0.014
TYROBP	TYRO protein tyrosine kinase binding protein	0.013
ADAMDEC1	ADAM-like, decysin 1	0.013
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.013
PVRL3	poliovirus receptor-related 3	0.013	Human
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.013
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.013	Mouse
DARC	Duffy blood group, chemokine receptor	0.013
TANK	TRAF family member-associated NFKB activator	0.013
HFE	hemochromatosis	0.013	Human
CD8B	CD8b molecule	0.013
SLAMF7	SLAM family member 7	0.013
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.013
IL1B	interleukin 1, beta	0.013
CTSW	cathepsin W	0.013
CD3D	CD3d molecule, delta (CD3-TCR complex)	0.012
PYHIN1	pyrin and HIN domain family, member 1	0.012
ZNF512B	zinc finger protein 512B	0.012
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.012
SLAMF8	SLAM family member 8	0.012
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.012
TRAF3IP2	TRAF3 interacting protein 2	0.012
IL4	interleukin 4	0.012	Mouse
C16orf53	chromosome 16 open reading frame 53	0.012
CLEC10A	C-type lectin domain family 10, member A	0.012
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.012
LITAF	lipopolysaccharide-induced TNF factor	0.012
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.012
SH2D2A	SH2 domain containing 2A	0.012
TPP1	tripeptidyl peptidase I	0.012
VSIG4	V-set and immunoglobulin domain containing 4	0.012
MRAS	muscle RAS oncogene homolog	0.011
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.011
IL21R	interleukin 21 receptor	0.011
C2	complement component 2	0.011
VAMP4	vesicle-associated membrane protein 4	0.011
CH25H	cholesterol 25-hydroxylase	0.011
SNX3	sorting nexin 3	0.011
CFB	complement factor B	0.011
PRKCQ	protein kinase C, theta	0.011
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.011
CMKLR1	chemokine-like receptor 1	0.011
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.011
IL13	interleukin 13	0.011
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.011
CFI	complement factor I	0.011
TLR7	toll-like receptor 7	0.011
SH3BGRL	SH3 domain binding glutamic acid-rich protein like	0.011
HCST	hematopoietic cell signal transducer	0.011
CD1C	CD1c molecule	0.011
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.010
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.010
SOCS1	suppressor of cytokine signaling 1	0.010
GPR18	G protein-coupled receptor 18	0.010
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.010	Human
NUMB	numb homolog (Drosophila)	0.010
KLRC4	killer cell lectin-like receptor subfamily C, member 4	0.010	Human
CCL20	chemokine (C-C motif) ligand 20	0.010	Human