IMP

Process View

Mus musculus

16 genes annotated in mouse

ectodermal placode formation

The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ectodermal placode formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ectodermal placode formation" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	0.996
Otx2	orthodenticle homolog 2 (Drosophila)	0.985
Tcfap2a	transcription factor AP-2, alpha	0.888	Zebrafish
Sox2	SRY-box containing gene 2	0.887
Pax2	paired box gene 2	0.883	Zebrafish
Pax3	paired box gene 3	0.870
Prrx1	paired related homeobox 1	0.830
Fgf8	fibroblast growth factor 8	0.824	Zebrafish
Gli3	GLI-Kruppel family member GLI3	0.817
Eya1	eyes absent 1 homolog (Drosophila)	0.785	Fly
Pitx2	paired-like homeodomain transcription factor 2	0.704
Foxg1	forkhead box G1	0.636
Fgf3	fibroblast growth factor 3	0.532	Zebrafish
Shh	sonic hedgehog	0.524
Tbx3	T-box 3	0.495
Hand1	heart and neural crest derivatives expressed transcript 1	0.494
Bmp4	bone morphogenetic protein 4	0.481
Gbx2	gastrulation brain homeobox 2	0.481
Ctnnb1	catenin (cadherin associated protein), beta 1	0.433
Sox11	SRY-box containing gene 11	0.389	Mouse
Msx2	homeobox, msh-like 2	0.356
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.339
Alx1	ALX homeobox 1	0.315
Lrp6	low density lipoprotein receptor-related protein 6	0.311
Dok2	docking protein 2	0.310	Mouse
Hoxa1	homeobox A1	0.302
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.302
Alx4	aristaless-like homeobox 4	0.296
Pitx1	paired-like homeodomain transcription factor 1	0.272
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.239
Dlx5	distal-less homeobox 5	0.230
Lmx1a	LIM homeobox transcription factor 1 alpha	0.225
Nodal	nodal	0.196
Rarg	retinoic acid receptor, gamma	0.194
Hoxd13	homeobox D13	0.191
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.177
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.171
Sall4	sal-like 4 (Drosophila)	0.165
Hmx3	H6 homeobox 3	0.163
Msx1	homeobox, msh-like 1	0.152	Zebrafish
Fgf10	fibroblast growth factor 10	0.152
Lef1	lymphoid enhancer binding factor 1	0.150
Smad6	MAD homolog 6 (Drosophila)	0.144
Nanog	Nanog homeobox	0.138
Runx2	runt related transcription factor 2	0.136
Isl1	ISL1 transcription factor, LIM/homeodomain	0.131
Zeb1	zinc finger E-box binding homeobox 1	0.128
Pou3f3	POU domain, class 3, transcription factor 3	0.128	Mouse
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.124	Mouse
Smo	smoothened homolog (Drosophila)	0.116
Otx1	orthodenticle homolog 1 (Drosophila)	0.116
Pax6	paired box gene 6	0.109
Bdnf	brain derived neurotrophic factor	0.108
Dok1	docking protein 1	0.107	Mouse
Col2a1	collagen, type II, alpha 1	0.106
Pten	phosphatase and tensin homolog	0.105
Pou5f1	POU domain, class 5, transcription factor 1	0.104	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.101
Bmp7	bone morphogenetic protein 7	0.098
Gata3	GATA binding protein 3	0.095	Zebrafish
Tcfap2c	transcription factor AP-2, gamma	0.095	Zebrafish
Gsc	goosecoid homeobox	0.095
Snai1	snail homolog 1 (Drosophila)	0.094
Vangl2	vang-like 2 (van gogh, Drosophila)	0.092
Sall3	sal-like 3 (Drosophila)	0.088
Zic3	zinc finger protein of the cerebellum 3	0.088
Foxc1	forkhead box C1	0.087
Gsk3b	glycogen synthase kinase 3 beta	0.087
Wnt1	wingless-related MMTV integration site 1	0.081
Foxh1	forkhead box H1	0.080
Rarb	retinoic acid receptor, beta	0.078
En2	engrailed 2	0.077
Dlx1	distal-less homeobox 1	0.073
Sox3	SRY-box containing gene 3	0.071	Zebrafish Mouse
Lrp5	low density lipoprotein receptor-related protein 5	0.066	Mouse
Pax9	paired box gene 9	0.065
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.063
Alx3	aristaless-like homeobox 3	0.059
Tbx15	T-box 15	0.058	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.058
Foxa2	forkhead box A2	0.057
Hoxa13	homeobox A13	0.057
Neurod1	neurogenic differentiation 1	0.057
Tbx10	T-box 10	0.055	Mouse
Ece1	endothelin converting enzyme 1	0.054
Nog	noggin	0.054
Grb2	growth factor receptor bound protein 2	0.054
Sim1	single-minded homolog 1 (Drosophila)	0.054
Tbx2	T-box 2	0.054
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.053
Hoxb1	homeobox B1	0.052
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.050
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.049
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.047
Plxnd1	plexin D1	0.047
Sin3a	transcriptional regulator, SIN3A (yeast)	0.046
Lhx1	LIM homeobox protein 1	0.045
Wnt3a	wingless-related MMTV integration site 3A	0.045
Ptk2	PTK2 protein tyrosine kinase 2	0.045
Tbx5	T-box 5	0.044	Mouse
Jag1	jagged 1	0.043
Fgfr1	fibroblast growth factor receptor 1	0.043
Irx3	Iroquois related homeobox 3 (Drosophila)	0.042
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.042
Edar	ectodysplasin-A receptor	0.042
Pou3f1	POU domain, class 3, transcription factor 1	0.041	Mouse
Inpp5d	inositol polyphosphate-5-phosphatase D	0.040
Hand2	heart and neural crest derivatives expressed transcript 2	0.040
Emx1	empty spiracles homolog 1 (Drosophila)	0.038
Rac1	RAS-related C3 botulinum substrate 1	0.037	Mouse
Zic2	zinc finger protein of the cerebellum 2	0.037
T	brachyury	0.037	Mouse
Ptprb	protein tyrosine phosphatase, receptor type, B	0.036
Tlx3	T-cell leukemia, homeobox 3	0.036
Hmha1	histocompatibility (minor) HA-1	0.035
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.035
Pax8	paired box gene 8	0.035	Zebrafish
Foxf1a	forkhead box F1a	0.035
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.034
Hoxb4	homeobox B4	0.034
Foxd2	forkhead box D2	0.033
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.033	Mouse Fly
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.031
Vegfa	vascular endothelial growth factor A	0.031
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.031
Sall1	sal-like 1 (Drosophila)	0.031
Emx2	empty spiracles homolog 2 (Drosophila)	0.031
Phox2a	paired-like homeobox 2a	0.030
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.030
Sox9	SRY-box containing gene 9	0.030	Zebrafish Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.030
Pkd1	polycystic kidney disease 1 homolog	0.030
Gdf3	growth differentiation factor 3	0.030
Tead3	TEA domain family member 3	0.029
Atoh7	atonal homolog 7 (Drosophila)	0.029
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.028
Hes5	hairy and enhancer of split 5 (Drosophila)	0.028
Inhbb	inhibin beta-B	0.027
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.027
Lhx9	LIM homeobox protein 9	0.026
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.026
Fgfr3	fibroblast growth factor receptor 3	0.026
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.026
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.026
Axin1	axin 1	0.025	Zebrafish
Nf1	neurofibromatosis 1	0.024
En1	engrailed 1	0.024
Csk	c-src tyrosine kinase	0.023
Egfr	epidermal growth factor receptor	0.023
Pou3f4	POU domain, class 3, transcription factor 4	0.023	Mouse
Hoxa3	homeobox A3	0.023
Scn5a	sodium channel, voltage-gated, type V, alpha	0.022
Smad1	MAD homolog 1 (Drosophila)	0.022
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.022
Atoh1	atonal homolog 1 (Drosophila)	0.022
Efnb2	ephrin B2	0.022
Pbx1	pre B-cell leukemia transcription factor 1	0.021
Hoxd11	homeobox D11	0.021
Hoxa2	homeobox A2	0.021
Gdnf	glial cell line derived neurotrophic factor	0.021
Yap1	yes-associated protein 1	0.021
Cxadr	coxsackie virus and adenovirus receptor	0.021
Dll4	delta-like 4 (Drosophila)	0.020
Pou4f3	POU domain, class 4, transcription factor 3	0.020	Mouse
She	src homology 2 domain-containing transforming protein E	0.020
Meox2	mesenchyme homeobox 2	0.020
Twist2	twist homolog 2 (Drosophila)	0.020
Inhba	inhibin beta-A	0.020
Hoxd1	homeobox D1	0.020
Zfhx3	zinc finger homeobox 3	0.019
Bcl2	B-cell leukemia/lymphoma 2	0.019
Flt1	FMS-like tyrosine kinase 1	0.019
Gdf11	growth differentiation factor 11	0.019
Npc1	Niemann Pick type C1	0.019
Efna2	ephrin A2	0.018
Hhex	hematopoietically expressed homeobox	0.018
Uncx	UNC homeobox	0.018
Eya4	eyes absent 4 homolog (Drosophila)	0.018	Fly
Rnf2	ring finger protein 2	0.018
Nynrin	NYN domain and retroviral integrase containing	0.018
Htt	huntingtin	0.018
Fzd6	frizzled homolog 6 (Drosophila)	0.018
Onecut1	one cut domain, family member 1	0.017
Sox1	SRY-box containing gene 1	0.017
Prrx2	paired related homeobox 2	0.017
Rdh10	retinol dehydrogenase 10 (all-trans)	0.017
Chrd	chordin	0.017	Zebrafish
Npas1	neuronal PAS domain protein 1	0.017
Shox2	short stature homeobox 2	0.017
Dab1	disabled homolog 1 (Drosophila)	0.017
Gja3	gap junction protein, alpha 3	0.017
Il11	interleukin 11	0.016
Wnt6	wingless-related MMTV integration site 6	0.016
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.016
Dlx6	distal-less homeobox 6	0.016
Insm1	insulinoma-associated 1	0.016
Lyl1	lymphoblastomic leukemia 1	0.016
Hoxa11	homeobox A11	0.016
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.016
Hesx1	homeobox gene expressed in ES cells	0.016
Ighmbp2	immunoglobulin mu binding protein 2	0.016
Tcfcp2l1	transcription factor CP2-like 1	0.016
Plcg1	phospholipase C, gamma 1	0.016
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.016
Dok3	docking protein 3	0.015	Mouse
Foxj1	forkhead box J1	0.015
Sim2	single-minded homolog 2 (Drosophila)	0.015
Bcar1	breast cancer anti-estrogen resistance 1	0.015
Ptk7	PTK7 protein tyrosine kinase 7	0.015
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.015
Rax	retina and anterior neural fold homeobox	0.015
Mc1r	melanocortin 1 receptor	0.015
Irx5	Iroquois related homeobox 5 (Drosophila)	0.015
Skor1	SKI family transcriptional corepressor 1	0.015
Rara	retinoic acid receptor, alpha	0.015
Id1	inhibitor of DNA binding 1	0.015
Zbtb7b	zinc finger and BTB domain containing 7B	0.014
Mmp24	matrix metallopeptidase 24	0.014
Hdac1	histone deacetylase 1	0.014
Anpep	alanyl (membrane) aminopeptidase	0.014
Arid1a	AT rich interactive domain 1A (SWI-like)	0.014
Dlx2	distal-less homeobox 2	0.014
Ybx2	Y box protein 2	0.014
Fmnl1	formin-like 1	0.014
Fgf5	fibroblast growth factor 5	0.014
a	nonagouti	0.014
Foxa1	forkhead box A1	0.014
Notch3	Notch gene homolog 3 (Drosophila)	0.014
Cux1	cut-like homeobox 1	0.013
Nos3	nitric oxide synthase 3, endothelial cell	0.013
Hoxb3	homeobox B3	0.013
Pou2f2	POU domain, class 2, transcription factor 2	0.013	Mouse
Cldn6	claudin 6	0.013
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.013
Fgf4	fibroblast growth factor 4	0.013
Isl2	insulin related protein 2 (islet 2)	0.013
Msi1	Musashi homolog 1(Drosophila)	0.013
Plac1	placental specific protein 1	0.013
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.013
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.013
Cdx2	caudal type homeobox 2	0.013
Xrn1	5'-3' exoribonuclease 1	0.013
Hoxd3	homeobox D3	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.013
Gata6	GATA binding protein 6	0.013
Hif1a	hypoxia inducible factor 1, alpha subunit	0.013
Satb2	special AT-rich sequence binding protein 2	0.013
Pou3f2	POU domain, class 3, transcription factor 2	0.012	Mouse
Aplnr	apelin receptor	0.012
S1pr2	sphingosine-1-phosphate receptor 2	0.012
Apc	adenomatosis polyposis coli	0.012
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.012
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.012
Wnt7b	wingless-related MMTV integration site 7B	0.012
Btbd17	BTB (POZ) domain containing 17	0.012
Gli2	GLI-Kruppel family member GLI2	0.012
Hoxb13	homeobox B13	0.012
Mixl1	Mix1 homeobox-like 1 (Xenopus laevis)	0.012
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.012	Mouse
Plekho1	pleckstrin homology domain containing, family O member 1	0.012
Foxb1	forkhead box B1	0.012
Irx4	Iroquois related homeobox 4 (Drosophila)	0.012
Irx1	Iroquois related homeobox 1 (Drosophila)	0.012
Trp63	transformation related protein 63	0.012
Vax1	ventral anterior homeobox containing gene 1	0.012
Nfia	nuclear factor I/A	0.012
Nppa	natriuretic peptide type A	0.012
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.012
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.012
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.012
Dlx4	distal-less homeobox 4	0.011	Zebrafish
Gas1	growth arrest specific 1	0.011
Msx3	homeobox, msh-like 3	0.011	Zebrafish
Vstm2b	V-set and transmembrane domain containing 2B	0.011
Phox2b	paired-like homeobox 2b	0.011
Axin2	axin2	0.011
Tal1	T-cell acute lymphocytic leukemia 1	0.011
Irx2	Iroquois related homeobox 2 (Drosophila)	0.011
Arhgap1	Rho GTPase activating protein 1	0.011
Pcdh1	protocadherin 1	0.011
Bicc1	bicaudal C homolog 1 (Drosophila)	0.011
Neurog2	neurogenin 2	0.011
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.011
Fgf17	fibroblast growth factor 17	0.011
Esrrb	estrogen related receptor, beta	0.011
Fbrs	fibrosin	0.011
Myf5	myogenic factor 5	0.011
Acvr2b	activin receptor IIB	0.011
Tead1	TEA domain family member 1	0.011
Gata1	GATA binding protein 1	0.011
Sox13	SRY-box containing gene 13	0.011
S1pr4	sphingosine-1-phosphate receptor 4	0.011
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.010
Fes	feline sarcoma oncogene	0.010
Nkx6-1	NK6 homeobox 1	0.010
Krt14	keratin 14	0.010
Lhx5	LIM homeobox protein 5	0.010
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.010
Sept1	septin 1	0.010
Olig2	oligodendrocyte transcription factor 2	0.010
Eomes	eomesodermin homolog (Xenopus laevis)	0.010	Mouse
Cd160	CD160 antigen	0.010
Lhx2	LIM homeobox protein 2	0.010
Sstr5	somatostatin receptor 5	0.010
Rybp	RING1 and YY1 binding protein	0.010
Fhl3	four and a half LIM domains 3	0.010
Vasp	vasodilator-stimulated phosphoprotein	0.010
Card10	caspase recruitment domain family, member 10	0.010
Foxc2	forkhead box C2	0.010
Epas1	endothelial PAS domain protein 1	0.010
Sox4	SRY-box containing gene 4	0.010	Mouse