IMP

Process View

Mus musculus

1 genes annotated in mouse

Multi-species View

regulation of lens epithelial cell proliferation

GO:2001109

Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of lens epithelial cell proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of lens epithelial cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Gli3	GLI-Kruppel family member GLI3	1.000
Pax3	paired box gene 3	0.999
Bmp4	bone morphogenetic protein 4	0.995
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.993
Isl1	ISL1 transcription factor, LIM/homeodomain	0.993
Fgf8	fibroblast growth factor 8	0.988
Tcfap2a	transcription factor AP-2, alpha	0.987
Meox2	mesenchyme homeobox 2	0.963
Pax6	paired box gene 6	0.959
Otx2	orthodenticle homolog 2 (Drosophila)	0.956
Foxc1	forkhead box C1	0.945
Pax2	paired box gene 2	0.919
Eya1	eyes absent 1 homolog (Drosophila)	0.907
Pitx2	paired-like homeodomain transcription factor 2	0.903
Sox11	SRY-box containing gene 11	0.892
Fgf10	fibroblast growth factor 10	0.798
Sox4	SRY-box containing gene 4	0.781	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.768
Fgfr3	fibroblast growth factor receptor 3	0.740
Hand1	heart and neural crest derivatives expressed transcript 1	0.736
Smo	smoothened homolog (Drosophila)	0.729
Foxc2	forkhead box C2	0.723
Nf1	neurofibromatosis 1	0.718
Rarb	retinoic acid receptor, beta	0.690
Fgfr1	fibroblast growth factor receptor 1	0.682
Efnb2	ephrin B2	0.676
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.671
Tgfb2	transforming growth factor, beta 2	0.652
Gli2	GLI-Kruppel family member GLI2	0.627
Prrx1	paired related homeobox 1	0.626
Ptprb	protein tyrosine phosphatase, receptor type, B	0.573
Msx1	homeobox, msh-like 1	0.569
Alx4	aristaless-like homeobox 4	0.557
Prrx2	paired related homeobox 2	0.535
Tbx1	T-box 1	0.527
Vegfa	vascular endothelial growth factor A	0.495
Emx1	empty spiracles homolog 1 (Drosophila)	0.491
Jag1	jagged 1	0.459
Foxg1	forkhead box G1	0.454
Emx2	empty spiracles homolog 2 (Drosophila)	0.440
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.433
Rarg	retinoic acid receptor, gamma	0.409
Gata4	GATA binding protein 4	0.404
Zeb1	zinc finger E-box binding homeobox 1	0.399
Gbx2	gastrulation brain homeobox 2	0.387
Hes1	hairy and enhancer of split 1 (Drosophila)	0.383
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.326
Ctnnb1	catenin (cadherin associated protein), beta 1	0.323
Otx1	orthodenticle homolog 1 (Drosophila)	0.317
Vangl2	vang-like 2 (van gogh, Drosophila)	0.308
Hand2	heart and neural crest derivatives expressed transcript 2	0.303
Bmp7	bone morphogenetic protein 7	0.302
Cdh5	cadherin 5	0.279
Rara	retinoic acid receptor, alpha	0.278
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.267
Fgf3	fibroblast growth factor 3	0.260
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.258
Pou5f1	POU domain, class 5, transcription factor 1	0.257
Sox2	SRY-box containing gene 2	0.254	Mouse
Ret	ret proto-oncogene	0.248
Col1a1	collagen, type I, alpha 1	0.247
She	src homology 2 domain-containing transforming protein E	0.245
Alx1	ALX homeobox 1	0.241
Ednra	endothelin receptor type A	0.232
Sox9	SRY-box containing gene 9	0.204	Mouse
Sall4	sal-like 4 (Drosophila)	0.180
Pitx1	paired-like homeodomain transcription factor 1	0.177
Col2a1	collagen, type II, alpha 1	0.175
Rb1	retinoblastoma 1	0.174
Dlx5	distal-less homeobox 5	0.170
Hes5	hairy and enhancer of split 5 (Drosophila)	0.159
Ptch1	patched homolog 1	0.153
Ntf3	neurotrophin 3	0.146
Alx3	aristaless-like homeobox 3	0.146
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.142
Hoxa1	homeobox A1	0.137
Cldn5	claudin 5	0.137
Sall3	sal-like 3 (Drosophila)	0.133
Rxra	retinoid X receptor alpha	0.117
Gsc	goosecoid homeobox	0.115
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.113
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.106
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.102
Trp63	transformation related protein 63	0.102
Gata3	GATA binding protein 3	0.101
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.099
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.098
Tcfap2c	transcription factor AP-2, gamma	0.092
Trp53	transformation related protein 53	0.091
Lmx1b	LIM homeobox transcription factor 1 beta	0.087
Kdr	kinase insert domain protein receptor	0.083
Pbx1	pre B-cell leukemia transcription factor 1	0.082
Atoh7	atonal homolog 7 (Drosophila)	0.082
Lef1	lymphoid enhancer binding factor 1	0.078
Sox18	SRY-box containing gene 18	0.078	Mouse
Zic3	zinc finger protein of the cerebellum 3	0.076
Tbx3	T-box 3	0.074
Aplnr	apelin receptor	0.073
Nos3	nitric oxide synthase 3, endothelial cell	0.072
Nanog	Nanog homeobox	0.069
Hoxa5	homeobox A5	0.067
Emcn	endomucin	0.066
Hoxa3	homeobox A3	0.060
Robo4	roundabout homolog 4 (Drosophila)	0.056
Tbx15	T-box 15	0.055
Nkx6-1	NK6 homeobox 1	0.054
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.054
Lrp2	low density lipoprotein receptor-related protein 2	0.053
Nog	noggin	0.052
Ldb2	LIM domain binding 2	0.051
Tcf15	transcription factor 15	0.050
Hoxa2	homeobox A2	0.050
Tbx2	T-box 2	0.050
Bmper	BMP-binding endothelial regulator	0.050
Ednrb	endothelin receptor type B	0.047
Fgf4	fibroblast growth factor 4	0.047
Dlx1	distal-less homeobox 1	0.047
Chrd	chordin	0.046
Apc	adenomatosis polyposis coli	0.045
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.045
Bcl6b	B-cell CLL/lymphoma 6, member B	0.045
Kit	kit oncogene	0.044
Rasip1	Ras interacting protein 1	0.043
Pthlh	parathyroid hormone-like peptide	0.043
Msx2	homeobox, msh-like 2	0.043
Wnt3a	wingless-related MMTV integration site 3A	0.042
Esam	endothelial cell-specific adhesion molecule	0.041
Twist2	twist homolog 2 (Drosophila)	0.040
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.039
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.038
Smad6	MAD homolog 6 (Drosophila)	0.038
Bdnf	brain derived neurotrophic factor	0.036
Hoxd13	homeobox D13	0.036
Hoxb13	homeobox B13	0.035
Gata6	GATA binding protein 6	0.034
Hesx1	homeobox gene expressed in ES cells	0.033
Kitl	kit ligand	0.032
Efna2	ephrin A2	0.032
Meox1	mesenchyme homeobox 1	0.032
Lmx1a	LIM homeobox transcription factor 1 alpha	0.031
Lhx1	LIM homeobox protein 1	0.031
Edar	ectodysplasin-A receptor	0.031
Gja4	gap junction protein, alpha 4	0.030
Ushbp1	Usher syndrome 1C binding protein 1	0.030
Pou3f1	POU domain, class 3, transcription factor 1	0.029
Sox3	SRY-box containing gene 3	0.029	Mouse
Btbd17	BTB (POZ) domain containing 17	0.029
Sfn	stratifin	0.029
Hhex	hematopoietically expressed homeobox	0.028
Lhx3	LIM homeobox protein 3	0.027
Adcy4	adenylate cyclase 4	0.026
Pou4f2	POU domain, class 4, transcription factor 2	0.026
Runx2	runt related transcription factor 2	0.026
Bmp2	bone morphogenetic protein 2	0.026
Tek	endothelial-specific receptor tyrosine kinase	0.025
Gdnf	glial cell line derived neurotrophic factor	0.025
Bmp5	bone morphogenetic protein 5	0.025
Wt1	Wilms tumor 1 homolog	0.025
Mesp1	mesoderm posterior 1	0.024
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.024
Krt17	keratin 17	0.024
Flt1	FMS-like tyrosine kinase 1	0.024
Eng	endoglin	0.024
Hoxb3	homeobox B3	0.023
Tbx10	T-box 10	0.023
Notch3	Notch gene homolog 3 (Drosophila)	0.023
Ebf3	early B-cell factor 3	0.023
Tcf21	transcription factor 21	0.023
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.022
Gas1	growth arrest specific 1	0.022
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.021
Phox2b	paired-like homeobox 2b	0.021
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.021
Eda	ectodysplasin-A	0.021
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.020
Krt16	keratin 16	0.020
Mitf	microphthalmia-associated transcription factor	0.020
Pou3f3	POU domain, class 3, transcription factor 3	0.020
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.020
Mmp15	matrix metallopeptidase 15	0.020
Fgf18	fibroblast growth factor 18	0.020
Dll1	delta-like 1 (Drosophila)	0.019
Nrtn	neurturin	0.019
Sall1	sal-like 1 (Drosophila)	0.019
Nkx2-1	NK2 homeobox 1	0.019
Sox17	SRY-box containing gene 17	0.019	Mouse
Icam2	intercellular adhesion molecule 2	0.019
Mn1	meningioma 1	0.019
Wnt6	wingless-related MMTV integration site 6	0.019
Tcfcp2l1	transcription factor CP2-like 1	0.018
Lhx5	LIM homeobox protein 5	0.018
Olig2	oligodendrocyte transcription factor 2	0.018
Insm1	insulinoma-associated 1	0.018
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.017
En2	engrailed 2	0.017
Dll4	delta-like 4 (Drosophila)	0.017
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.017
Foxi3	forkhead box I3	0.017
Pax9	paired box gene 9	0.017
Hrh2	histamine receptor H2	0.016
En1	engrailed 1	0.016
Arx	aristaless related homeobox	0.016
Uncx	UNC homeobox	0.016
Gata2	GATA binding protein 2	0.016
Pou3f4	POU domain, class 3, transcription factor 4	0.016
Ihh	Indian hedgehog	0.015
Tead4	TEA domain family member 4	0.015
Sox7	SRY-box containing gene 7	0.015	Mouse
Mmrn2	multimerin 2	0.015
Kcnk2	potassium channel, subfamily K, member 2	0.015
Gja1	gap junction protein, alpha 1	0.015
Gpr152	G protein-coupled receptor 152	0.014
Lrp6	low density lipoprotein receptor-related protein 6	0.014
Barhl2	BarH-like 2 (Drosophila)	0.014
Acvr1	activin A receptor, type 1	0.014
Egfr	epidermal growth factor receptor	0.014
Neurog2	neurogenin 2	0.014
Nodal	nodal	0.014
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.013
Fxyd2	FXYD domain-containing ion transport regulator 2	0.013
Zic2	zinc finger protein of the cerebellum 2	0.013
Spry4	sprouty homolog 4 (Drosophila)	0.012
Pten	phosphatase and tensin homolog	0.012
Gh	growth hormone	0.012
Pax1	paired box gene 1	0.012
BC024139	cDNA sequence BC024139	0.012
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.012
Foxf2	forkhead box F2	0.012
Neurod1	neurogenic differentiation 1	0.011
Myl7	myosin, light polypeptide 7, regulatory	0.011
LOC639910	hypothetical protein LOC639910	0.011
Pcdh12	protocadherin 12	0.011
Dmrt1	doublesex and mab-3 related transcription factor 1	0.011
Npr3	natriuretic peptide receptor 3	0.011
Hoxa4	homeobox A4	0.011
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.011
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.011
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.011
Irx5	Iroquois related homeobox 5 (Drosophila)	0.011
Bmp6	bone morphogenetic protein 6	0.011
Egfl7	EGF-like domain 7	0.011
Clic3	chloride intracellular channel 3	0.011
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.011
Arhgef15	Rho guanine nucleotide exchange factor (GEF) 15	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.010
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.010
Hoxa13	homeobox A13	0.010
Foxf1a	forkhead box F1a	0.010
Cabp7	calcium binding protein 7	0.010