IMP

Process View

Mus musculus

3 genes annotated in mouse

mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis

The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Pou5f1	POU domain, class 5, transcription factor 1	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Sox2	SRY-box containing gene 2	1.000
Eya1	eyes absent 1 homolog (Drosophila)	0.999
Nanog	Nanog homeobox	0.999
Gli3	GLI-Kruppel family member GLI3	0.996
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.996
Fgf8	fibroblast growth factor 8	0.988
Hoxa1	homeobox A1	0.984
Foxc1	forkhead box C1	0.984
Tbx1	T-box 1	0.983
Pax3	paired box gene 3	0.979
Chd7	chromodomain helicase DNA binding protein 7	0.978
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.978
Otx2	orthodenticle homolog 2 (Drosophila)	0.973
Fgf10	fibroblast growth factor 10	0.969
Gbx2	gastrulation brain homeobox 2	0.964
Rarg	retinoic acid receptor, gamma	0.963
Emx2	empty spiracles homolog 2 (Drosophila)	0.957
Foxc2	forkhead box C2	0.953
Foxg1	forkhead box G1	0.947
Tcfcp2l1	transcription factor CP2-like 1	0.946
Vangl2	vang-like 2 (van gogh, Drosophila)	0.945
Lhx1	LIM homeobox protein 1	0.907
Tcfap2a	transcription factor AP-2, alpha	0.901
Dlx5	distal-less homeobox 5	0.885
Msx1	homeobox, msh-like 1	0.884
Zeb1	zinc finger E-box binding homeobox 1	0.858
Esrrb	estrogen related receptor, beta	0.852
Pitx2	paired-like homeodomain transcription factor 2	0.852
Rarb	retinoic acid receptor, beta	0.846
Jag1	jagged 1	0.811
Hoxd11	homeobox D11	0.794
Sall4	sal-like 4 (Drosophila)	0.778	Mouse
Rxra	retinoid X receptor alpha	0.776
Lmx1a	LIM homeobox transcription factor 1 alpha	0.774
Otx1	orthodenticle homolog 1 (Drosophila)	0.773
Hand1	heart and neural crest derivatives expressed transcript 1	0.772
Hoxa3	homeobox A3	0.762
Gli2	GLI-Kruppel family member GLI2	0.719
Fgf3	fibroblast growth factor 3	0.706
Bmp4	bone morphogenetic protein 4	0.701
Sall3	sal-like 3 (Drosophila)	0.700	Mouse
Gata3	GATA binding protein 3	0.682
Fgfr1	fibroblast growth factor receptor 1	0.666
Nog	noggin	0.601
Smo	smoothened homolog (Drosophila)	0.581
Sox9	SRY-box containing gene 9	0.523
Rara	retinoic acid receptor, alpha	0.491
Grhl2	grainyhead-like 2 (Drosophila)	0.461
Lef1	lymphoid enhancer binding factor 1	0.453
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.451
Bmp7	bone morphogenetic protein 7	0.447
Prrx1	paired related homeobox 1	0.438
Wnt9b	wingless-type MMTV integration site 9B	0.416
Tbx10	T-box 10	0.399
Hoxd3	homeobox D3	0.397
Chrd	chordin	0.397
Pax6	paired box gene 6	0.396
Hoxa2	homeobox A2	0.394
Ctnnb1	catenin (cadherin associated protein), beta 1	0.369
Fgfr3	fibroblast growth factor receptor 3	0.365
Msx2	homeobox, msh-like 2	0.309
Hmx3	H6 homeobox 3	0.307
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.287
T	brachyury	0.258
Efnb2	ephrin B2	0.248
Isl1	ISL1 transcription factor, LIM/homeodomain	0.223
Hoxa11	homeobox A11	0.222
Gsc	goosecoid homeobox	0.216
Sox11	SRY-box containing gene 11	0.188
Hoxb3	homeobox B3	0.184
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.178
Hand2	heart and neural crest derivatives expressed transcript 2	0.157
Ednra	endothelin receptor type A	0.153
En1	engrailed 1	0.146
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.140
Zic3	zinc finger protein of the cerebellum 3	0.126
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.119
Zic2	zinc finger protein of the cerebellum 2	0.114
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.102
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.101
Trp63	transformation related protein 63	0.101
Wnt3a	wingless-related MMTV integration site 3A	0.095
Wt1	Wilms tumor 1 homolog	0.094
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.093
Alx3	aristaless-like homeobox 3	0.092
Col2a1	collagen, type II, alpha 1	0.091
Hes5	hairy and enhancer of split 5 (Drosophila)	0.091
Foxi1	forkhead box I1	0.091
Wnt1	wingless-related MMTV integration site 1	0.079
Hoxd13	homeobox D13	0.075
Runx2	runt related transcription factor 2	0.071
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.071
Pou4f3	POU domain, class 4, transcription factor 3	0.067
Ret	ret proto-oncogene	0.064
Tcfap2c	transcription factor AP-2, gamma	0.064
Tgfb2	transforming growth factor, beta 2	0.062
Emx1	empty spiracles homolog 1 (Drosophila)	0.061
Pten	phosphatase and tensin homolog	0.061
Lmx1b	LIM homeobox transcription factor 1 beta	0.061
Hoxa5	homeobox A5	0.060
Sall1	sal-like 1 (Drosophila)	0.057
Mta1	metastasis associated 1	0.056
Hmx2	H6 homeobox 2	0.053
Nkx2-1	NK2 homeobox 1	0.053
Sox3	SRY-box containing gene 3	0.052
Ptch1	patched homolog 1	0.052
Pax1	paired box gene 1	0.051	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.051
Bcl2	B-cell leukemia/lymphoma 2	0.051
Prrx2	paired related homeobox 2	0.051
Twist2	twist homolog 2 (Drosophila)	0.050
Pitx1	paired-like homeodomain transcription factor 1	0.049
Hoxb1	homeobox B1	0.048
Pbx1	pre B-cell leukemia transcription factor 1	0.048
Mta3	metastasis associated 3	0.047
Psen1	presenilin 1	0.046
Thrb	thyroid hormone receptor beta	0.043
Alx4	aristaless-like homeobox 4	0.043
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.041
Dlx2	distal-less homeobox 2	0.041
Lhx3	LIM homeobox protein 3	0.039
Uncx	UNC homeobox	0.038
Fgf15	fibroblast growth factor 15	0.037
Gdf11	growth differentiation factor 11	0.037
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.036
Lrp2	low density lipoprotein receptor-related protein 2	0.035
Gatad2b	GATA zinc finger domain containing 2B	0.035
Grem1	gremlin 1	0.035
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.033
Nodal	nodal	0.032
Sox4	SRY-box containing gene 4	0.032
Hoxc4	homeobox C4	0.031
Ar	androgen receptor	0.029
En2	engrailed 2	0.028
Rb1	retinoblastoma 1	0.028
Dll1	delta-like 1 (Drosophila)	0.028
Hes1	hairy and enhancer of split 1 (Drosophila)	0.028
Gpr50	G-protein-coupled receptor 50	0.027
Bdnf	brain derived neurotrophic factor	0.026
Lhx9	LIM homeobox protein 9	0.026
Kiss1	KiSS-1 metastasis-suppressor	0.026
Sim1	single-minded homolog 1 (Drosophila)	0.025
Hesx1	homeobox gene expressed in ES cells	0.024
Fgf4	fibroblast growth factor 4	0.024
Dll3	delta-like 3 (Drosophila)	0.024
Foxh1	forkhead box H1	0.023
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.023
Hoxa10	homeobox A10	0.022
Nkx3-2	NK3 homeobox 2	0.022
Myo6	myosin VI	0.021
Tshr	thyroid stimulating hormone receptor	0.021
Tlx3	T-cell leukemia, homeobox 3	0.021
Efna2	ephrin A2	0.020
Tbx15	T-box 15	0.020
Vegfa	vascular endothelial growth factor A	0.020
Pax9	paired box gene 9	0.020	Mouse
Foxd2	forkhead box D2	0.020
Meox2	mesenchyme homeobox 2	0.019
Tshz1	teashirt zinc finger family member 1	0.019
Hoxd9	homeobox D9	0.019
Klf5	Kruppel-like factor 5	0.019
Rdh10	retinol dehydrogenase 10 (all-trans)	0.018
Hoxd1	homeobox D1	0.018
Mesp2	mesoderm posterior 2	0.018
Eomes	eomesodermin homolog (Xenopus laevis)	0.018
Hoxc5	homeobox C5	0.018
Lamc1	laminin, gamma 1	0.017
Mesp1	mesoderm posterior 1	0.017
Ptk7	PTK7 protein tyrosine kinase 7	0.016
Csf3	colony stimulating factor 3 (granulocyte)	0.016
Hoxa4	homeobox A4	0.016
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.016
Ihh	Indian hedgehog	0.016
Bmper	BMP-binding endothelial regulator	0.016
Cd8a	CD8 antigen, alpha chain	0.016
Neurog1	neurogenin 1	0.016
Trap1a	tumor rejection antigen P1A	0.015
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.015
Insm1	insulinoma-associated 1	0.015
Esr1	estrogen receptor 1 (alpha)	0.015
Pou4f2	POU domain, class 4, transcription factor 2	0.015
Bmp2	bone morphogenetic protein 2	0.014
Neurog3	neurogenin 3	0.014
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.014
Slc26a4	solute carrier family 26, member 4	0.014
Gdnf	glial cell line derived neurotrophic factor	0.014
Matn3	matrilin 3	0.014
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.014
Dlx1	distal-less homeobox 1	0.014
Lhx5	LIM homeobox protein 5	0.013
Pou3f1	POU domain, class 3, transcription factor 1	0.013
Hoxd12	homeobox D12	0.013
Hoxc8	homeobox C8	0.013
Zfp143	zinc finger protein 143	0.013
Foxa2	forkhead box A2	0.013
Pax8	paired box gene 8	0.013
Zfp219	zinc finger protein 219	0.013
Tbx3	T-box 3	0.013
Phlda2	pleckstrin homology-like domain, family A, member 2	0.013
Onecut1	one cut domain, family member 1	0.013
Tgfbr2	transforming growth factor, beta receptor II	0.013
Wnt6	wingless-related MMTV integration site 6	0.013
Gdf3	growth differentiation factor 3	0.013
Adra2b	adrenergic receptor, alpha 2b	0.012
Tcf21	transcription factor 21	0.012
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.012
Vrtn	vertebrae development homolog (pig)	0.012
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.012
Foxe1	forkhead box E1	0.012
Hoxb9	homeobox B9	0.012
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.012
Alx1	ALX homeobox 1	0.012
Cd19	CD19 antigen	0.011
Wnt4	wingless-related MMTV integration site 4	0.011
Thra	thyroid hormone receptor alpha	0.011
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Zfp42	zinc finger protein 42	0.011
Oc90	otoconin 90	0.011
Hoxb2	homeobox B2	0.011
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.011
Gjb5	gap junction protein, beta 5	0.011
Foxn1	forkhead box N1	0.011
Emid2	EMI domain containing 2	0.011
Ntf3	neurotrophin 3	0.011
Dpf2	D4, zinc and double PHD fingers family 2	0.010
Osr1	odd-skipped related 1 (Drosophila)	0.010
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.010
Chd4	chromodomain helicase DNA binding protein 4	0.010